BP

GO:0000435

positive regulation of transcription from RNA polymerase II promoter by galactose

Any process involving galactose that activates or increases the rate of transcription from an RNA polymerase II promoter.

IDA

BP

GO:0002155

regulation of thyroid hormone mediated signaling pathway

Any process that modulates the frequency, rate or extent of a thyroid hormone mediated signaling pathway.

IEA

BP

GO:0006351

transcription, DNA-templated

The cellular synthesis of RNA on a template of DNA.

IDA

BP

GO:0007595

lactation

The secretion of milk by the mammary gland.

IEA

BP

GO:0008584

male gonad development

The process whose specific outcome is the progression of the male gonad over time, from its formation to the mature structure.

IEA

BP

GO:0015721

bile acid and bile salt transport

The directed movement of bile acid and bile salts into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

TAS

BP

GO:0021549

cerebellum development

The process whose specific outcome is the progression of the cerebellum over time, from its formation to the mature structure. The cerebellum is the portion of the brain in the back of the head between the cerebrum and the pons. In mice, the cerebellum controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills.

IEA

BP

GO:0021766

hippocampus development

The progression of the hippocampus over time from its initial formation until its mature state.

IEA

BP

GO:0021854

hypothalamus development

The progression of the hypothalamus region of the forebrain, from its initial formation to its mature state.

IEA

BP

GO:0021987

cerebral cortex development

The progression of the cerebral cortex over time from its initial formation until its mature state. The cerebral cortex is the outer layered region of the telencephalon.

IEA

BP

GO:0030521

androgen receptor signaling pathway

Any series of molecular signals generated as a consequence of an androgen binding to its receptor.

NAS

BP

GO:0030522

intracellular receptor signaling pathway

Any series of molecular signals initiated by a ligand binding to an receptor located within a cell.

IBA

BP

GO:0032355

response to estradiol

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by estradiol, a C18 steroid hormone hydroxylated at C3 and C17 that acts as a potent estrogen.

IEA

BP

GO:0032526

response to retinoic acid

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a retinoic acid stimulus.

IEA

BP

GO:0032570

response to progesterone

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a progesterone stimulus.

IEA

BP

GO:0032870

cellular response to hormone stimulus

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hormone stimulus.

IBA

BP

GO:0043065

positive regulation of apoptotic process

Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process.

IEA

BP

GO:0043967

histone H4 acetylation

The modification of histone H4 by the addition of an acetyl group.

IEA

BP

GO:0044255

cellular lipid metabolic process

The chemical reactions and pathways involving lipids, as carried out by individual cells.

TAS

BP

GO:0044849

estrous cycle

A type of ovulation cycle, which occurs in most mammalian therian females, where the endometrium is resorbed if pregnancy does not occur.

IEA

BP

GO:0045666

positive regulation of neuron differentiation

Any process that activates or increases the frequency, rate or extent of neuron differentiation.

IEA

BP

GO:0045893

positive regulation of transcription, DNA-templated

Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.

IDA|NAS

BP

GO:0045925

positive regulation of female receptivity

Any process that activates or increases the receptiveness of a female to male advances.

IEA

BP

GO:0045944

positive regulation of transcription from RNA polymerase II promoter

Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.

IDA|NAS

BP

GO:0060179

male mating behavior

The specific behavior of a male organism that is associated with reproduction.

IEA

BP

GO:0060713

labyrinthine layer morphogenesis

The process in which the labyrinthine layer of the placenta is generated and organized.

IEA

BP

GO:1904017

cellular response to Thyroglobulin triiodothyronine

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a Thyroglobulin triiodothyronine stimulus.

IEA

BP

GO:2001038

regulation of cellular response to drug

Any process that modulates the frequency, rate or extent of cellular response to drug.

IEA

CC

GO:0000790

nuclear chromatin

The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome in the nucleus.

IDA

CC

GO:0005654

nucleoplasm

That part of the nuclear content other than the chromosomes or the nucleolus.

TAS

CC

GO:0005737

cytoplasm

All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

IEA

CC

GO:0043005

neuron projection

A prolongation or process extending from a nerve cell, e.g. an axon or dendrite.

IEA

MF

GO:0001012

RNA polymerase II regulatory region DNA binding

Interacting selectively and non-covalently with a DNA region that controls the transcription of a region of DNA by RNA polymerase II. Binding may occur as a sequence specific interaction or as an interaction observed only once a factor has been recruited to the DNA by other factors.

IEA

MF

GO:0001105

RNA polymerase II transcription coactivator activity

Interacting selectively and non-covalently with an RNA polymerase II (RNAP II) regulatory transcription factor and also with the RNAP II basal transcription machinery in order to increase the frequency, rate or extent of transcription. Cofactors generally do not bind DNA, but rather mediate protein-protein interactions between activating transcription factors and the basal RNAP II transcription machinery.

NAS

MF

GO:0003682

chromatin binding

Interacting selectively and non-covalently with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.

IEA

MF

GO:0003713

transcription coactivator activity

Interacting selectively and non-covalently with a activating transcription factor and also with the basal transcription machinery in order to increase the frequency, rate or extent of transcription. Cofactors generally do not bind the template nucleic acid, but rather mediate protein-protein interactions between activating transcription factors and the basal transcription machinery.

IDA|NAS

MF

GO:0004402

histone acetyltransferase activity

Catalysis of the reaction: acetyl-CoA + histone = CoA + acetyl-histone.

IEA

MF

GO:0005515

protein binding

Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).

IPI

MF

GO:0016922

ligand-dependent nuclear receptor binding

Interacting selectively and non-covalently, in a ligand dependent manner, with a nuclear receptor protein.

IPI

MF

GO:0019899

enzyme binding

Interacting selectively and non-covalently with any enzyme.

IPI

MF

GO:0030331

estrogen receptor binding

Interacting selectively and non-covalently with an estrogen receptor.

IEA

MF

GO:0030374

ligand-dependent nuclear receptor transcription coactivator activity

The function of a transcription cofactor that activates transcription in conjuction with a ligand-dependent nuclear receptor from a RNA polymerase II promoter; does not bind DNA itself.

IDA

MF

GO:0032403

protein complex binding

Interacting selectively and non-covalently with any protein complex (a complex of two or more proteins that may include other nonprotein molecules).

IEA

MF

GO:0033142

progesterone receptor binding

Interacting selectively and non-covalently with a progesterone receptor.

IEA

MF

GO:0035257

nuclear hormone receptor binding

Interacting selectively and non-covalently with a nuclear hormone receptor, a ligand-dependent receptor found in the nucleus of the cell.

IDA

MF

GO:0046965

retinoid X receptor binding

Interacting selectively and non-covalently with a retinoid X receptor.

IEA

MF

GO:0046983

protein dimerization activity

The formation of a protein dimer, a macromolecular structure consists of two noncovalently associated identical or nonidentical subunits.

IEA

MF

GO:0047485

protein N-terminus binding

Interacting selectively and non-covalently with a protein N-terminus, the end of any peptide chain at which the 2-amino (or 2-imino) function of a constituent amino acid is not attached in peptide linkage to another amino-acid residue.

IPI

MF

GO:0050681

androgen receptor binding

Interacting selectively and non-covalently with an androgen receptor.

NAS