BP

GO:0006468

protein phosphorylation

The process of introducing a phosphate group on to a protein.

IDA

BP

GO:0006913

nucleocytoplasmic transport

The directed movement of molecules between the nucleus and the cytoplasm.

IEA

BP

GO:0007049

cell cycle

The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division.

IEA

BP

GO:0007165

signal transduction

The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.

IEA

BP

GO:0010976

positive regulation of neuron projection development

Any process that increases the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites).

IDA

BP

GO:0032091

negative regulation of protein binding

Any process that stops, prevents, or reduces the frequency, rate or extent of protein binding.

IDA

BP

GO:0032880

regulation of protein localization

Any process that modulates the frequency, rate or extent of any process in which a protein is transported to, or maintained in, a specific location.

IDA

BP

GO:0033138

positive regulation of peptidyl-serine phosphorylation

Any process that activates or increases the frequency, rate or extent of the phosphorylation of peptidyl-serine.

IMP

BP

GO:0043393

regulation of protein binding

Any process that modulates the frequency, rate or extent of protein binding.

IDA

BP

GO:0045944

positive regulation of transcription from RNA polymerase II promoter

Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.

IMP

BP

GO:0046827

positive regulation of protein export from nucleus

Any process that activates or increases the frequency, rate or extent of directed movement of proteins from the nucleus into the cytoplasm.

IDA

BP

GO:0051147

regulation of muscle cell differentiation

Any process that modulates the frequency, rate or extent of muscle cell differentiation.

IDA

BP

GO:0051149

positive regulation of muscle cell differentiation

Any process that activates or increases the frequency, rate or extent of muscle cell differentiation.

IMP

BP

GO:0051835

positive regulation of synapse structural plasticity

Any process that activates, maintains or increases the frequency, rate or extent of synaptic structural plasticity.

IMP

BP

GO:0060143

positive regulation of syncytium formation by plasma membrane fusion

Any process that increases the frequency, rate or extent of the formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells.

IMP

BP

GO:0060999

positive regulation of dendritic spine development

Any process that increases the rate, frequency, or extent of dendritic spine development, the process whose specific outcome is the progression of the dendritic spine over time, from its formation to the mature structure.

IMP

BP

GO:0071902

positive regulation of protein serine/threonine kinase activity

Any process that increases the rate, frequency, or extent of protein serine/threonine kinase activity.

IDA

BP

GO:1901985

positive regulation of protein acetylation

Any process that activates or increases the frequency, rate or extent of protein acetylation.

IMP

CC

GO:0005634

nucleus

A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

IEA

CC

GO:0005737

cytoplasm

All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

IEA

MF

GO:0004683

calmodulin-dependent protein kinase activity

Catalysis of the reactions: ATP + a protein serine = ADP + protein serine phosphate; and ATP + a protein threonine = ADP + protein threonine phosphate. These reactions require the presence of calcium-bound calmodulin.

ISS

MF

GO:0005515

protein binding

Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).

IPI

MF

GO:0005516

calmodulin binding

Interacting selectively and non-covalently with calmodulin, a calcium-binding protein with many roles, both in the calcium-bound and calcium-free states.

IEA

MF

GO:0005524

ATP binding

Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.

IEA