BP

GO:0006897

endocytosis

A vesicle-mediated transport process in which cells take up external materials or membrane constituents by the invagination of a small region of the plasma membrane to form a new membrane-bounded vesicle.

IMP

BP

GO:0006906

vesicle fusion

Fusion of the membrane of a transport vesicle with its target membrane.

IMP

BP

GO:0016189

synaptic vesicle to endosome fusion

Fusion of a synaptic vesicle with an endosome.

TAS

BP

GO:0039694

viral RNA genome replication

The replication of a viral RNA genome.

IMP

BP

GO:0045022

early endosome to late endosome transport

The directed movement of substances, in membrane-bounded vesicles, from the early sorting endosomes to the late sorting endosomes; transport occurs along microtubules and can be experimentally blocked with microtubule-depolymerizing drugs.

NAS

CC

GO:0005737

cytoplasm

All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

TAS

CC

GO:0005769

early endosome

A membrane-bounded organelle that receives incoming material from primary endocytic vesicles that have been generated by clathrin-dependent and clathrin-independent endocytosis; vesicles fuse with the early endosome to deliver cargo for sorting into recycling or degradation pathways.

IDA

CC

GO:0005829

cytosol

The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

IDA

CC

GO:0005969

serine-pyruvate aminotransferase complex

An enzyme complex that catalyzes the formation of hydroxypyruvate and alanine from serine and pyruvate.

IEA

CC

GO:0016020

membrane

A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.

TAS

CC

GO:0019897

extrinsic component of plasma membrane

The component of a plasma membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.

IDA

CC

GO:0031410

cytoplasmic vesicle

A vesicle found in the cytoplasm of a cell.

IEA

CC

GO:0031901

early endosome membrane

The lipid bilayer surrounding an early endosome.

IEA

CC

GO:0044308

axonal spine

A spine that originates from the axon, usually from the initial segment.

IEA

CC

GO:0055037

recycling endosome

An organelle consisting of a network of tubules that functions in targeting molecules, such as receptors transporters and lipids, to the plasma membrane.

IEA

CC

GO:0070062

extracellular exosome

A membrane-bounded vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.

IDA

CC

GO:0098793

presynapse

The part of a synapse that is part of the presynaptic cell.

IEA

MF

GO:0005515

protein binding

Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).

IPI

MF

GO:0005516

calmodulin binding

Interacting selectively and non-covalently with calmodulin, a calcium-binding protein with many roles, both in the calcium-bound and calcium-free states.

NAS

MF

GO:0005545

1-phosphatidylinositol binding

Interacting selectively and non-covalently with phosphatidylinositol, any glycophospholipid with its sn-glycerol 3-phosphate residue is esterified to the 1-hydroxyl group of 1D-myo-inositol.

IDA

MF

GO:0008270

zinc ion binding

Interacting selectively and non-covalently with zinc (Zn) ions.

TAS

MF

GO:0030742

GTP-dependent protein binding

Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules) using energy from the hydrolysis of GTP.

IDA

MF

GO:0042803

protein homodimerization activity

Interacting selectively and non-covalently with an identical protein to form a homodimer.

IDA