Protein Description

Gene Symbol COLQ
Entrez ID 8292
Uniprot ID Q9Y215
Description collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase
Chromosomal Location chr3: 15,450,133-15,521,751
Ontology GO ID GO Term Definition Evidence

BP

GO:0001507

acetylcholine catabolic process in synaptic cleft

The chemical reactions and pathways resulting in the breakdown of acetylcholine that occurs in the synaptic cleft during synaptic transmission.

TAS

BP

GO:0008105

asymmetric protein localization

Any process in which a protein is transported to, or maintained in, a specific location such that it is distributed asymmetrically.

TAS

BP

GO:0008582

regulation of synaptic growth at neuromuscular junction

Any process that modulates the frequency, rate or extent of synaptic growth at neuromuscular junctions.

IEA

BP

GO:0071340

skeletal muscle acetylcholine-gated channel clustering

The accumulation of acetylcholine-gated cation channels in a narrow, central region of muscle fibers, in apposition to nerve terminals.

IEA

BP

GO:0090150

establishment of protein localization to membrane

The directed movement of a protein to a specific location in a membrane.

IEA

CC

GO:0005581

collagen trimer

A protein complex consisting of three collagen chains assembled into a left-handed triple helix. These trimers typically assemble into higher order structures.

IEA

CC

GO:0005605

basal lamina

A thin sheet of proteoglycans and glycoproteins, especially laminin, secreted by cells as an extracellular matrix.

TAS

CC

GO:0005615

extracellular space

That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.

TAS

CC

GO:0005886

plasma membrane

The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

IEA

CC

GO:0030054

cell junction

A cellular component that forms a specialized region of connection between two or more cells or between a cell and the extracellular matrix. At a cell junction, anchoring proteins extend through the plasma membrane to link cytoskeletal proteins in one cell to cytoskeletal proteins in neighboring cells or to proteins in the extracellular matrix.

IEA

CC

GO:0031594

neuromuscular junction

The junction between the axon of a motor neuron and a muscle fiber. In response to the arrival of action potentials, the presynaptic button releases molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane of the muscle fiber, leading to a change in post-synaptic potential.

IEA

CC

GO:0043083

synaptic cleft

The narrow gap that separates the presynaptic and postsynaptic membranes, into which neurotransmitter is released.

IEA

Domain ID Description

IPR011936

Myxococcus cysteine-rich repeat

No pathways found.

No diseases found.

No tissues found.

No databases found.

Pubmed ID Author Year Title

22617121

Ouandaogo et al.

2012

Differences in transcriptomic profiles of human cumulus cells isolated from oocytes at GV, MI and MII stages after in vivo andin vitro oocyte maturation

Gene Symbol Entrez ID Uniprot ID Score

MUSK

4593

O15146

0.52

BCHE

590

P06276

0.58

ACHE

43

P22303

0.85