| Gene Symbol | YWHAE |
| Entrez ID | 7531 |
| Uniprot ID | P62258 |
| Description | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon |
| Chromosomal Location | chr17: 1,344,272-1,400,378 |
| Ontology | GO ID | GO Term | Definition | Evidence |
|---|---|---|---|---|
|
BP |
GO:0000086 |
G2/M transition of mitotic cell cycle |
The mitotic cell cycle transition by which a cell in G2 commits to M phase. The process begins when the kinase activity of M cyclin/CDK complex reaches a threshold high enough for the cell cycle to proceed. This is accomplished by activating a positive feedback loop that results in the accumulation of unphosphorylated and active M cyclin/CDK complex. |
TAS |
|
BP |
GO:0001764 |
neuron migration |
The characteristic movement of an immature neuron from germinal zones to specific positions where they will reside as they mature. |
IEA |
|
BP |
GO:0003064 |
regulation of heart rate by hormone |
The process in which the hormones modulates the rate of heart muscle contraction. A hormone is one of a group of substances formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells, in the same organism, upon which they have a specific regulatory action. |
NAS |
|
BP |
GO:0006605 |
protein targeting |
The process of targeting specific proteins to particular regions of the cell, typically membrane-bounded subcellular organelles. Usually requires an organelle specific protein sequence motif. |
IEA |
|
BP |
GO:0016032 |
viral process |
A multi-organism process in which a virus is a participant. The other participant is the host. Includes infection of a host cell, replication of the viral genome, and assembly of progeny virus particles. In some cases the viral genetic material may integrate into the host genome and only subsequently, under particular circumstances, 'complete' its life cycle. |
IEA |
|
BP |
GO:0021762 |
substantia nigra development |
The progression of the substantia nigra over time from its initial formation until its mature state. The substantia nigra is the layer of gray substance that separates the posterior parts of the cerebral peduncles (tegmentum mesencephali) from the anterior parts; it normally includes a posterior compact part with many pigmented cells (pars compacta) and an anterior reticular part whose cells contain little pigment (pars reticularis). |
IEP |
|
BP |
GO:0021766 |
hippocampus development |
The progression of the hippocampus over time from its initial formation until its mature state. |
IEA |
|
BP |
GO:0021987 |
cerebral cortex development |
The progression of the cerebral cortex over time from its initial formation until its mature state. The cerebral cortex is the outer layered region of the telencephalon. |
IEA |
|
BP |
GO:0035329 |
hippo signaling |
The series of molecular signals mediated by the serine/threonine kinase Hippo or one of its orthologs. In Drosophila, Hippo in complex with the scaffold protein Salvador (Sav), phosphorylates and activates Warts (Wts), which in turn phosphorylates and inactivates the Yorkie (Yki) transcriptional activator. The core fly components hippo, sav, wts and mats are conserved in mammals as STK4/3 (MST1/2), SAV1/WW45, LATS1/2 and MOB1. |
TAS |
|
BP |
GO:0035556 |
intracellular signal transduction |
The process in which a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell. |
TAS |
|
BP |
GO:0043154 |
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process |
Any process that stops, prevents, or reduces the frequency, rate or extent of a cysteine-type endopeptidase activity involved in the apoptotic process. |
TAS |
|
BP |
GO:0060306 |
regulation of membrane repolarization |
Any process that modulates the establishment or extent of a membrane potential in the polarizing direction towards the resting potential, usually from positive to negative. |
IDA |
|
BP |
GO:0061024 |
membrane organization |
A process which results in the assembly, arrangement of constituent parts, or disassembly of a membrane. A membrane is a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins. |
TAS |
|
BP |
GO:0086013 |
membrane repolarization during cardiac muscle cell action potential |
The process in which ions are transported across a membrane such that the cardiac muscle cell plasma membrane potential changes in the direction from the positive membrane potential at the peak of the action potential towards the negative resting potential. |
IC |
|
BP |
GO:0086091 |
regulation of heart rate by cardiac conduction |
A cardiac conduction process that modulates the frequency or rate of heart contraction. |
IC |
|
BP |
GO:0098609 |
cell-cell adhesion |
The attachment of one cell to another cell via adhesion molecules. |
IEA |
|
BP |
GO:1900034 |
regulation of cellular response to heat |
Any process that modulates the frequency, rate or extent of cellular response to heat. |
TAS |
|
BP |
GO:1900740 |
positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway |
Any process that activates or increases the frequency, rate or extent of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway. |
TAS |
|
BP |
GO:1901016 |
regulation of potassium ion transmembrane transporter activity |
Any process that modulates the frequency, rate or extent of potassium ion transmembrane transporter activity. |
IDA |
|
BP |
GO:1902309 |
negative regulation of peptidyl-serine dephosphorylation |
Any process that stops, prevents or reduces the frequency, rate or extent of peptidyl-serine dephosphorylation. |
IDA |
|
CC |
GO:0005739 |
mitochondrion |
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration. |
IEA |
|
CC |
GO:0005829 |
cytosol |
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. |
TAS |
|
CC |
GO:0005871 |
kinesin complex |
Any complex that includes a dimer of molecules from the kinesin superfamily, a group of related proteins that contain an extended region of predicted alpha-helical coiled coil in the main chain that likely produces dimerization. The native complexes of several kinesin family members have also been shown to contain additional peptides, often designated light chains as all of the noncatalytic subunits that are currently known are smaller than the chain that contains the motor unit. Kinesin complexes generally possess a force-generating enzymatic activity, or motor, which converts the free energy of the gamma phosphate bond of ATP into mechanical work. |
IEA |
|
CC |
GO:0005913 |
cell-cell adherens junction |
An adherens junction which connects a cell to another cell. |
IDA |
|
CC |
GO:0005925 |
focal adhesion |
Small region on the surface of a cell that anchors the cell to the extracellular matrix and that forms a point of termination of actin filaments. |
IDA |
|
CC |
GO:0016020 |
membrane |
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it. |
IDA |
|
CC |
GO:0030424 |
axon |
The long process of a neuron that conducts nerve impulses, usually away from the cell body to the terminals and varicosities, which are sites of storage and release of neurotransmitter. |
IEA |
|
CC |
GO:0030659 |
cytoplasmic vesicle membrane |
The lipid bilayer surrounding a cytoplasmic vesicle. |
TAS |
|
CC |
GO:0042470 |
melanosome |
A tissue-specific, membrane-bounded cytoplasmic organelle within which melanin pigments are synthesized and stored. Melanosomes are synthesized in melanocyte cells. |
IEA |
|
CC |
GO:0070062 |
extracellular exosome |
A membrane-bounded vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm. |
IDA |
|
MF |
GO:0005515 |
protein binding |
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules). |
IPI |
|
MF |
GO:0015459 |
potassium channel regulator activity |
Modulates the activity of a potassium channel. |
IDA |
|
MF |
GO:0019899 |
enzyme binding |
Interacting selectively and non-covalently with any enzyme. |
IPI |
|
MF |
GO:0019904 |
protein domain specific binding |
Interacting selectively and non-covalently with a specific domain of a protein. |
IEA |
|
MF |
GO:0023026 |
MHC class II protein complex binding |
Interacting selectively and non-covalently with the class II major histocompatibility complex. |
IDA |
|
MF |
GO:0031625 |
ubiquitin protein ligase binding |
Interacting selectively and non-covalently with a ubiquitin protein ligase enzyme, any of the E3 proteins. |
IPI |
|
MF |
GO:0042826 |
histone deacetylase binding |
Interacting selectively and non-covalently with the enzyme histone deacetylase. |
IPI |
|
MF |
GO:0044325 |
ion channel binding |
Interacting selectively and non-covalently with one or more specific sites on an ion channel, a protein complex that spans a membrane and forms a water-filled channel across the phospholipid bilayer allowing selective ion transport down its electrochemical gradient. |
IPI |
|
MF |
GO:0044822 |
poly(A) RNA binding |
Interacting non-covalently with a poly(A) RNA, a RNA molecule which has a tail of adenine bases. |
IDA |
|
MF |
GO:0046982 |
protein heterodimerization activity |
Interacting selectively and non-covalently with a nonidentical protein to form a heterodimer. |
IPI |
|
MF |
GO:0050815 |
phosphoserine binding |
Interacting selectively and non-covalently with a phosphorylated serine residue within a protein. |
IPI |
|
MF |
GO:0051219 |
phosphoprotein binding |
Interacting selectively and non-covalently with a phosphorylated protein. |
IPI |
|
MF |
GO:0098641 |
cadherin binding involved in cell-cell adhesion |
Any cadherin binding that occurs as part of the process of cell-cell adhesion. |
IDA |
| Domain ID | Description |
|---|---|
|
IPR000308 |
14-3-3 protein |
|
IPR023409 |
14-3-3 protein, conserved site |
|
IPR023410 |
14-3-3 domain |
| Pathway ID | Pathway Term | Pathway Source |
|---|---|---|
|
hsa04110 |
Cell cycle |
KEGG |
|
hsa04114 |
Oocyte meiosis |
KEGG |
|
hsa04151 |
PI3K-Akt signaling pathway |
KEGG |
|
hsa04390 |
Hippo signaling pathway |
KEGG |
|
hsa04722 |
Neurotrophin signaling pathway |
KEGG |
|
hsa05169 |
Epstein-Barr virus infection |
KEGG |
|
hsa05203 |
Viral carcinogenesis |
KEGG |
|
WP536 |
Calcium Regulation in the Cardiac Cell |
WikiPathways |
|
WP706 |
Sudden Infant Death Syndrome (SIDS) Susceptibility Pathways |
WikiPathways |
|
WP289 |
Myometrial Relaxation and Contraction Pathways |
WikiPathways |
|
WP179 |
Cell Cycle |
WikiPathways |
|
WP3888 |
VEGFA-VEGFR2 Signaling Pathway |
WikiPathways |
| UMLS CUI | UMLS Term |
|---|---|
|
C0027627 |
Neoplasm Metastasis |
|
C0206630 |
Endometrial Stromal Sarcoma |
|
C0265219 |
Miller Dieker Syndrome |
|
C1955870 |
Classical Lissencephalies And Subcortical Band Heterotopias |
| Tissue | Cell Type |
|---|---|
|
adrenal gland |
glandular cells |
|
appendix |
lymphoid tissue |
|
bone marrow |
hematopoietic cells |
|
caudate |
neuronal cells |
|
cerebellum |
cells in molecular layer |
|
cerebral cortex |
neuronal cells |
|
endometrium |
glandular cells |
|
epididymis |
glandular cells |
|
fallopian tube |
glandular cells |
|
hippocampus |
neuronal cells |
|
liver |
bile duct cells |
|
lymph node |
germinal center cells |
|
lymph node |
non-germinal center cells |
|
parathyroid gland |
glandular cells |
|
placenta |
decidual cells |
|
placenta |
trophoblastic cells |
|
rectum |
glandular cells |
|
seminal vesicle |
glandular cells |
|
skin |
fibroblasts |
|
spleen |
cells in white pulp |
|
stomach |
glandular cells |
|
testis |
cells in seminiferous ducts |
|
tonsil |
non-germinal center cells |
|
tonsil |
squamous epithelial cells |
|
urinary bladder |
urothelial cells |
| Pubmed ID | Author | Year | Title |
|---|---|---|---|
|
22951915 |
Haozi et al. |
2012 |
Altered gene expression profile in cumulus cells of mature MII oocytes from patients with polycystic ovary syndrome |
| Gene Symbol | Entrez ID | Uniprot ID | Score |
|---|---|---|---|
|
ACAT2 |
39 |
Q9BWD1 |
0.49 |
|
ACTA2 |
59 |
P62736 |
0.49 |
|
CALR |
811 |
P27797 |
0.49 |
|
CENPE |
1062 |
Q02224 |
0.49 |
|
MAPK14 |
1432 |
Q16539 |
0.49 |
|
IL7R |
3575 |
P16871 |
0.49 |
|
POLR2D |
5433 |
O15514 |
0.49 |
|
SHMT2 |
6472 |
P34897 |
0.49 |
|
SNRPD1 |
6632 |
P62314 |
0.49 |
|
ZPR1 |
8882 |
O75312 |
0.49 |
|
CBX3 |
11335 |
Q13185 |
0.49 |
|
MACF1 |
23499 |
Q9UPN3 |
0.49 |
|
MCFD2 |
90411 |
Q8NI22 |
0.49 |
|
TBC1D3 |
414059 |
Q8IZP1 |
0.49 |
|
SNCA |
6622 |
P37840 |
0.52 |
|
TAZ |
6901 |
Q16635 |
0.52 |
|
TCEB3 |
6924 |
Q14241 |
0.52 |
|
BRD4 |
23476 |
O60885 |
0.52 |
|
VIM |
7431 |
P08670 |
0.55 |
|
PSMB2 |
5690 |
P49721 |
0.56 |
|
TBP |
6908 |
P20226 |
0.56 |
|
SAMSN1 |
64092 |
Q9NSI8 |
0.56 |
|
KRT18 |
3875 |
P05783 |
0.62 |
|
RGS3 |
5998 |
P49796 |
0.62 |
|
SRC |
6714 |
P12931 |
0.62 |
|
ADH1B |
125 |
P00325 |
0.63 |
|
ADH4 |
127 |
P08319 |
0.63 |
|
AGXT |
189 |
P21549 |
0.63 |
|
SLC25A6 |
293 |
P12236 |
0.63 |
|
SHROOM2 |
357 |
Q13796 |
0.63 |
|
ATP5A1 |
498 |
P25705 |
0.63 |
|
ATP5B |
506 |
P06576 |
0.63 |
|
ZFP36L2 |
678 |
P47974 |
0.63 |
|
CLNS1A |
1207 |
P54105 |
0.63 |
|
EEF1A2 |
1917 |
Q05639 |
0.63 |
|
EEF1G |
1937 |
P26641 |
0.63 |
|
EIF4B |
1975 |
P23588 |
0.63 |
|
HNRNPA1 |
3178 |
P09651 |
0.63 |
|
HNRNPA2B1 |
3181 |
P22626 |
0.63 |
|
HNRNPC |
3183 |
P07910 |
0.63 |
|
DNAJA1 |
3301 |
P31689 |
0.63 |
|
HSPA1A |
3303 |
P0DMV8 |
0.63 |
|
HSPA1B |
3304 |
P0DMV9 |
0.63 |
|
HSPA8 |
3312 |
P11142 |
0.63 |
|
HSP90AB1 |
3326 |
P08238 |
0.63 |
|
IGHG1 |
3500 |
P01857 |
0.63 |
|
ILF2 |
3608 |
Q12905 |
0.63 |
|
EIF3E |
3646 |
P60228 |
0.63 |
|
KIF5B |
3799 |
P33176 |
0.63 |
|
KLC1 |
3831 |
Q07866 |
0.63 |
|
ABLIM1 |
3983 |
O14639 |
0.63 |
|
LMO7 |
4008 |
Q8WWI1 |
0.63 |
|
LRMP |
4033 |
Q12912 |
0.63 |
|
MAP3K5 |
4217 |
Q99683 |
0.63 |
|
MLLT4 |
4301 |
P55196 |
0.63 |
|
NCBP1 |
4686 |
Q09161 |
0.63 |
|
PAFAH1B2 |
5049 |
P68402 |
0.63 |
|
PCBP1 |
5093 |
Q15365 |
0.63 |
|
CDK18 |
5129 |
Q07002 |
0.63 |
|
PFKFB2 |
5208 |
O60825 |
0.63 |
|
PHB |
5245 |
P35232 |
0.63 |
|
PPM1B |
5495 |
O75688 |
0.63 |
|
PPP1R2 |
5504 |
P41236 |
0.63 |
|
PRKCI |
5584 |
P41743 |
0.63 |
|
PRPS1 |
5631 |
P60891 |
0.63 |
|
PRPSAP1 |
5635 |
Q14558 |
0.63 |
|
PRPSAP2 |
5636 |
O60256 |
0.63 |
|
RAP1GDS1 |
5910 |
P52306 |
0.63 |
|
RBMY1A1 |
5940 |
P0DJD3 |
0.63 |
|
RCN2 |
5955 |
Q14257 |
0.63 |
|
RPL4 |
6124 |
P36578 |
0.63 |
|
RPL6 |
6128 |
Q02878 |
0.63 |
|
RPLP0 |
6175 |
P05388 |
0.63 |
|
RPS3 |
6188 |
P23396 |
0.63 |
|
RPS8 |
6202 |
P62241 |
0.63 |
|
SRSF1 |
6426 |
Q07955 |
0.63 |
|
SRSF2 |
6427 |
Q01130 |
0.63 |
|
SRSF4 |
6429 |
Q08170 |
0.63 |
|
SRSF6 |
6431 |
Q13247 |
0.63 |
|
SRSF7 |
6432 |
Q16629 |
0.63 |
|
TRA2B |
6434 |
P62995 |
0.63 |
|
MAP3K7 |
6885 |
O43318 |
0.63 |
|
TIAM1 |
7074 |
Q13009 |
0.63 |
|
TMPO |
7112 |
P42166 |
0.63 |
|
TP53BP2 |
7159 |
Q13625 |
0.63 |
|
TUBB2A |
7280 |
Q13885 |
0.63 |
|
UVRAG |
7405 |
Q9P2Y5 |
0.63 |
|
VASP |
7408 |
P50552 |
0.63 |
|
VCL |
7414 |
P18206 |
0.63 |
|
TUBA1A |
7846 |
Q71U36 |
0.63 |
|
RBM10 |
8241 |
P98175 |
0.63 |
|
VAMP8 |
8673 |
Q9BV40 |
0.63 |
|
KSR1 |
8844 |
Q8IVT5 |
0.63 |
|
RABEP1 |
9135 |
Q15276 |
0.63 |
|
DDX21 |
9188 |
Q9NR30 |
0.63 |
|
NOLC1 |
9221 |
Q14978 |
0.63 |
|
TRIP11 |
9321 |
Q15643 |
0.63 |
|
EIF4E2 |
9470 |
O60573 |
0.63 |
|
KIF23 |
9493 |
Q02241 |
0.63 |
|
BCAR1 |
9564 |
P56945 |
0.63 |
|
RUBCN |
9711 |
Q92622 |
0.63 |
|
GPRIN2 |
9721 |
O60269 |
0.63 |
|
KIAA0232 |
9778 |
Q92628 |
0.63 |
|
TLK1 |
9874 |
Q9UKI8 |
0.63 |
|
TBC1D4 |
9882 |
O60343 |
0.63 |
|
CHAF1A |
10036 |
Q13111 |
0.63 |
|
DCAF7 |
10238 |
P61962 |
0.63 |
|
PAK4 |
10298 |
O96013 |
0.63 |
|
TUBB4B |
10383 |
P68371 |
0.63 |
|
BAIAP2 |
10458 |
Q9UQB8 |
0.63 |
|
IPO8 |
10526 |
O15397 |
0.63 |
|
RUVBL2 |
10856 |
Q9Y230 |
0.63 |
|
SPIN1 |
10927 |
Q9Y657 |
0.63 |
|
CDC37 |
11140 |
Q16543 |
0.63 |
|
CEP250 |
11190 |
Q9BV73 |
0.63 |
|
PROSC |
11212 |
O94903 |
0.63 |
|
RASSF8 |
11228 |
Q8NHQ8 |
0.63 |
|
RAB11FIP2 |
22841 |
Q7L804 |
0.63 |
|
MAST3 |
23031 |
O60307 |
0.63 |
|
KIF1B |
23095 |
O60333 |
0.63 |
|
CLASP2 |
23122 |
O75122 |
0.63 |
|
MAST2 |
23139 |
Q6P0Q8 |
0.63 |
|
CLASP1 |
23332 |
Q7Z460 |
0.63 |
|
CRTC1 |
23373 |
Q6UUV9 |
0.63 |
|
SRGAP2 |
23380 |
O75044 |
0.63 |
|
HMHA1 |
23526 |
Q92619 |
0.63 |
|
SH3BP4 |
23677 |
Q9P0V3 |
0.63 |
|
TNFAIP8 |
25816 |
O95379 |
0.63 |
|
RCHY1 |
25898 |
Q96PM5 |
0.63 |
|
OSBPL3 |
26031 |
Q9H4L5 |
0.63 |
|
TBK1 |
29110 |
Q9UHD2 |
0.63 |
|
TMOD3 |
29766 |
Q9NYL9 |
0.63 |
|
PIK3R4 |
30849 |
Q99570 |
0.63 |
|
STOML2 |
30968 |
Q9UJZ1 |
0.63 |
|
UBXN1 |
51035 |
Q04323 |
0.63 |
|
PDZD11 |
51248 |
Q5EBL8 |
0.63 |
|
FAM13B |
51306 |
Q9NYF5 |
0.63 |
|
LIMA1 |
51474 |
Q9UHB6 |
0.63 |
|
LSR |
51599 |
Q86X29 |
0.63 |
|
ADAM22 |
53616 |
Q9P0K1 |
0.63 |
|
QPCTL |
54814 |
Q9NXS2 |
0.63 |
|
PARD3 |
56288 |
Q8TEW0 |
0.63 |
|
CGN |
57530 |
Q9P2M7 |
0.63 |
|
KLC2 |
64837 |
Q9H0B6 |
0.63 |
|
RASAL3 |
64926 |
Q86YV0 |
0.63 |
|
REEP1 |
65055 |
Q9H902 |
0.63 |
|
WNK1 |
65125 |
Q9H4A3 |
0.63 |
|
NADK |
65220 |
O95544 |
0.63 |
|
DOK3 |
79930 |
Q7L591 |
0.63 |
|
CFAP43 |
80217 |
Q8NDM7 |
0.63 |
|
RAB11FIP1 |
80223 |
Q6WKZ4 |
0.63 |
|
PLEKHO2 |
80301 |
Q8TD55 |
0.63 |
|
ENKD1 |
84080 |
Q9H0I2 |
0.63 |
|
TBC1D3F |
84218 |
A6NER0 |
0.63 |
|
CGNL1 |
84952 |
Q0VF96 |
0.63 |
|
KLC4 |
89953 |
Q9NSK0 |
0.63 |
|
CEP95 |
90799 |
Q96GE4 |
0.63 |
|
TUBA3E |
112714 |
Q6PEY2 |
0.63 |
|
HDX |
139324 |
Q7Z353 |
0.63 |
|
C11orf84 |
144097 |
Q9BUA3 |
0.63 |
|
KLC3 |
147700 |
Q6P597 |
0.63 |
|
SGK223 |
157285 |
Q86YV5 |
0.63 |
|
TUBB |
203068 |
P07437 |
0.63 |
|
HNRNPA3 |
220988 |
P51991 |
0.63 |
|
TUBB2B |
347733 |
Q9BVA1 |
0.63 |
|
ANKHD1 |
404734 |
Q8IWZ3 |
0.63 |
|
KAT8 |
84148 |
Q9H7Z6 |
0.65 |
|
CDK11B |
984 |
P21127 |
0.68 |
|
KANK1 |
23189 |
Q14678 |
0.68 |
|
KPNB1 |
3837 |
Q14974 |
0.70 |
|
PKP2 |
5318 |
Q99959 |
0.70 |
|
XPO1 |
7514 |
O14980 |
0.70 |
|
SF3B1 |
23451 |
O75533 |
0.70 |
|
STAC |
6769 |
Q99469 |
0.72 |
|
C1QBP |
708 |
Q07021 |
0.73 |
|
CSNK1A1 |
1452 |
P48729 |
0.73 |
|
NPM1 |
4869 |
P06748 |
0.73 |
|
TOP2A |
7153 |
P11388 |
0.73 |
|
SORBS2 |
8470 |
O94875 |
0.73 |
|
DENND4A |
10260 |
Q7Z401 |
0.73 |
|
TBC1D1 |
23216 |
Q86TI0 |
0.73 |
|
KIAA0930 |
23313 |
Q6ICG6 |
0.73 |
|
LARP1 |
23367 |
Q6PKG0 |
0.73 |
|
DISC1 |
27185 |
Q9NRI5 |
0.73 |
|
HIST1H4A; HIST1H4B; HIST1H4C; HIST1H4D; HIST1H4E; HIST1H4F; HIST1H4H; HIST1H4I; HIST1H4J; HIST1H4K; HIST1H4L; HIST2H4A; HIST2H4B; HIST4H4 |
121504 |
P62805 |
0.73 |
|
MAP3K10 |
4294 |
Q02779 |
0.76 |
|
IGF1R |
3480 |
P08069 |
0.78 |
|
KCNH2 |
3757 |
Q12809 |
0.79 |
|
USP8 |
9101 |
P40818 |
0.79 |
|
CALM2 |
805 |
P62158 |
0.80 |
|
CALM3 |
808 |
P62158 |
0.80 |
|
IRS2 |
8660 |
Q9Y4H2 |
0.80 |
|
CDKN1B |
1027 |
P46527 |
0.81 |
|
TSC2 |
7249 |
P49815 |
0.81 |
|
YWHAE |
7531 |
P62258 |
0.82 |
|
FAM53C |
51307 |
Q9NYF3 |
0.82 |
|
YWHAG |
7532 |
P61981 |
0.84 |
|
BAD |
572 |
Q92934 |
0.85 |
|
CDC25C |
995 |
P30307 |
0.85 |
|
KIF1C |
10749 |
O43896 |
0.85 |
|
TNFAIP3 |
7128 |
P21580 |
0.86 |
|
ARAF |
369 |
P10398 |
0.87 |
|
IRS1 |
3667 |
P35568 |
0.88 |
|
ATXN1 |
6310 |
P54253 |
0.88 |
|
TGFB1 |
7040 |
P01137 |
0.88 |
|
YWHAH |
7533 |
Q04917 |
0.88 |
|
MAP3K1 |
4214 |
Q13233 |
0.89 |
|
RAF1 |
5894 |
P04049 |
0.89 |
|
BEX3 |
27018 |
Q00994 |
0.89 |
|
CDC25B |
994 |
P30305 |
0.90 |
|
CRK |
1398 |
P46108 |
0.00 |
|
CSNK1D |
1453 |
P48730 |
0.00 |
|
CSNK1G2 |
1455 |
P78368 |
0.00 |
|
CSNK1G3 |
1456 |
Q9Y6M4 |
0.00 |
|
CTNNB1 |
1499 |
P35222 |
0.00 |
|
PLK1 |
5347 |
P53350 |
0.00 |
|
CSNK1G1 |
53944 |
Q9HCP0 |
0.00 |
|
APAF1 |
317 |
O14727 |
0.07 |
|
HNRNPL |
3191 |
P14866 |
0.49 |
|
PGK1 |
5230 |
P00558 |
0.49 |
|
PSMC1 |
5700 |
P62191 |
0.49 |
|
NPM3 |
10360 |
O75607 |
0.49 |
|
CENPJ |
55835 |
Q9HC77 |
0.49 |
|
ACTR6 |
64431 |
Q9GZN1 |
0.49 |
|
BCR |
613 |
P11274 |
0.52 |
|
RPGR |
6103 |
Q92834 |
0.52 |
|
SLC8A1 |
6546 |
P32418 |
0.52 |
|
SLC8A3 |
6547 |
P57103 |
0.52 |
|
PRDX6 |
9588 |
P30041 |
0.52 |
|
NCOR2 |
9612 |
Q9Y618 |
0.52 |
|
ARHGEF28 |
64283 |
Q8N1W1 |
0.52 |
|
PRKCG |
5582 |
P05129 |
0.55 |
|
AKAP13 |
11214 |
Q12802 |
0.55 |
|
GTF2B |
2959 |
Q00403 |
0.56 |
|
PPP2R2B |
5521 |
Q00005 |
0.56 |
|
FSCN1 |
6624 |
Q16658 |
0.56 |
|
TAF9 |
6880 |
Q16594 |
0.56 |
|
MEX3C |
51320 |
Q5U5Q3 |
0.56 |
|
DYRK1A |
1859 |
Q13627 |
0.62 |
|
ARHGEF2 |
9181 |
Q92974 |
0.62 |
|
HLA-DRB4 |
3126 |
P13762 |
0.63 |
|
AKT1 |
207 |
P31749 |
0.63 |
|
ASNS |
440 |
P08243 |
0.63 |
|
ATP2B1 |
490 |
P20020 |
0.63 |
|
ATP2B2 |
491 |
Q01814 |
0.63 |
|
ATP2B3 |
492 |
Q16720 |
0.63 |
|
ATP2B4 |
493 |
P23634 |
0.63 |
|
ALDH7A1 |
501 |
P49419 |
0.63 |
|
CAPN2 |
824 |
P17655 |
0.63 |
|
CAPNS1 |
826 |
P04632 |
0.63 |
|
CDC5L |
988 |
Q99459 |
0.63 |
|
CDK2 |
1017 |
P24941 |
0.63 |
|
TBCB |
1155 |
Q99426 |
0.63 |
|
CRY1 |
1407 |
Q16526 |
0.63 |
|
CRY2 |
1408 |
Q49AN0 |
0.63 |
|
CSNK1E |
1454 |
P49674 |
0.63 |
|
EGFR |
1956 |
P00533 |
0.63 |
|
EIF5 |
1983 |
P55010 |
0.63 |
|
EMD |
2010 |
P50402 |
0.63 |
|
DMTN |
2039 |
Q08495 |
0.63 |
|
ESR1 |
2099 |
P03372 |
0.63 |
|
FTH1 |
2495 |
P02794 |
0.63 |
|
G6PD |
2539 |
P11413 |
0.63 |
|
GAPDH |
2597 |
P04406 |
0.63 |
|
GLI1 |
2735 |
P08151 |
0.63 |
|
GLI3 |
2737 |
P10071 |
0.63 |
|
GP1BA |
2811 |
P07359 |
0.63 |
|
GSS |
2937 |
P48637 |
0.63 |
|
GSTA1 |
2938 |
P08263 |
0.63 |
|
HIVEP2 |
3097 |
P31629 |
0.63 |
|
HLA-DRA |
3122 |
P01903 |
0.63 |
|
HLA-DRB1 |
3123 |
P04229 |
0.63 |
|
HLA-DRB3 |
3125 |
P79483 |
0.63 |
|
HLA-DRB5 |
3127 |
Q30154 |
0.63 |
|
HSPB1 |
3315 |
P04792 |
0.63 |
|
ILK |
3611 |
Q13418 |
0.63 |
|
ITGA4 |
3676 |
P13612 |
0.63 |
|
JUN |
3725 |
P05412 |
0.63 |
|
MARK1 |
4139 |
Q9P0L2 |
0.63 |
|
MCM2 |
4171 |
P49736 |
0.63 |
|
MT-CO2 |
4513 |
P00403 |
0.63 |
|
MYH10 |
4628 |
P35580 |
0.63 |
|
NEDD8 |
4738 |
Q15843 |
0.63 |
|
NOS2 |
4843 |
P35228 |
0.63 |
|
NTRK1 |
4914 |
P04629 |
0.63 |
|
PAK2 |
5062 |
Q13177 |
0.63 |
|
PARK2 |
5071 |
O60260 |
0.63 |
|
PDHB |
5162 |
P11177 |
0.63 |
|
PHKG2 |
5261 |
P15735 |
0.63 |
|
PNLIP |
5406 |
P16233 |
0.63 |
|
PRKACA |
5566 |
P17612 |
0.63 |
|
PTMA |
5757 |
P06454 |
0.63 |
|
RARRES3 |
5920 |
Q9UL19 |
0.63 |
|
RPS6KA1 |
6195 |
Q15418 |
0.63 |
|
SUMO2 |
6613 |
P61956 |
0.63 |
|
SSFA2 |
6744 |
P28290 |
0.63 |
|
STK3 |
6788 |
Q13188 |
0.63 |
|
STK4 |
6789 |
Q13043 |
0.63 |
|
SYN2 |
6854 |
Q92777 |
0.63 |
|
HNF1A |
6927 |
P20823 |
0.63 |
|
UBE3A |
7337 |
Q05086 |
0.63 |
|
VCP |
7415 |
P55072 |
0.63 |
|
UBL4A |
8266 |
P11441 |
0.63 |
|
CUL3 |
8452 |
Q13618 |
0.63 |
|
CUL1 |
8454 |
Q13616 |
0.63 |
|
HDAC3 |
8841 |
O15379 |
0.63 |
|
BTRC |
8945 |
Q9Y297 |
0.63 |
|
GRAP2 |
9402 |
O75791 |
0.63 |
|
BAG3 |
9531 |
O95817 |
0.63 |
|
PDIA4 |
9601 |
P13667 |
0.63 |
|
NCOR1 |
9611 |
O75376 |
0.63 |
|
CEP57 |
9702 |
Q86XR8 |
0.63 |
|
ULK2 |
9706 |
Q8IYT8 |
0.63 |
|
KIAA0101 |
9768 |
Q15004 |
0.63 |
|
CUL7 |
9820 |
Q14999 |
0.63 |
|
PAN2 |
9924 |
Q504Q3 |
0.63 |
|
OXSR1 |
9943 |
O95747 |
0.63 |
|
RANBP9 |
10048 |
Q96S59 |
0.63 |
|
HUWE1 |
10075 |
Q7Z6Z7 |
0.63 |
|
CAP2 |
10486 |
P40123 |
0.63 |
|
STK25 |
10494 |
O00506 |
0.63 |
|
UBD |
10537 |
O15205 |
0.63 |
|
FERMT2 |
10979 |
Q96AC1 |
0.63 |
|
ADRM1 |
11047 |
Q16186 |
0.63 |
|
GABARAP |
11337 |
O95166 |
0.63 |
|
GABARAPL2 |
11345 |
P60520 |
0.63 |
|
FAN1 |
22909 |
Q9Y2M0 |
0.63 |
|
TRIM32 |
22954 |
Q13049 |
0.63 |
|
RAP1GAP2 |
23108 |
Q684P5 |
0.63 |
|
OBSL1 |
23363 |
O75147 |
0.63 |
|
SNAPIN |
23557 |
O95295 |
0.63 |
|
GABARAPL1 |
23710 |
Q9H0R8 |
0.63 |
|
CBY1 |
25776 |
Q9Y3M2 |
0.63 |
|
FBXO6 |
26270 |
Q9NRD1 |
0.63 |
|
MCTS1 |
28985 |
Q9ULC4 |
0.63 |
|
EEF2K |
29904 |
O00418 |
0.63 |
|
TRAT1 |
50852 |
Q6PIZ9 |
0.63 |
|
ISOC1 |
51015 |
Q96CN7 |
0.63 |
|
DACT1 |
51339 |
Q9NYF0 |
0.63 |
|
UCHL5 |
51377 |
Q9Y5K5 |
0.63 |
|
STK26 |
51765 |
Q9P289 |
0.63 |
|
DCUN1D1 |
54165 |
Q96GG9 |
0.63 |
|
ERRFI1 |
54206 |
Q9UJM3 |
0.63 |
|
UBE2R2 |
54926 |
Q712K3 |
0.63 |
|
MSL2 |
55167 |
Q9HCI7 |
0.63 |
|
OGFOD1 |
55239 |
Q8N543 |
0.63 |
|
ZNF839 |
55778 |
A8K0R7 |
0.63 |
|
MARK4 |
57787 |
Q96L34 |
0.63 |
|
SCPEP1 |
59342 |
Q9HB40 |
0.63 |
|
CCDC8 |
83987 |
Q9H0W5 |
0.63 |
|
MEX3B |
84206 |
Q6ZN04 |
0.63 |
|
NKD2 |
85409 |
Q969F2 |
0.63 |
|
UNK |
85451 |
Q9C0B0 |
0.63 |
|
SIK1 |
150094 |
P57059 |
0.63 |
|
TEX33 |
339669 |
O43247 |
0.63 |
|
KCNK3 |
3777 |
O14649 |
0.65 |
|
SLC8A2 |
6543 |
Q9UPR5 |
0.65 |
|
KCNK9 |
51305 |
Q9NPC2 |
0.65 |
|
KCNK15 |
60598 |
Q9H427 |
0.65 |
|
RASGRF1 |
5923 |
Q13972 |
0.67 |
|
REM1 |
28954 |
O75628 |
0.67 |
|
HSF1 |
3297 |
Q00613 |
0.69 |
|
ING1 |
3621 |
Q9UK53 |
0.70 |
|
PAK1 |
5058 |
Q13153 |
0.70 |
|
TWF2 |
11344 |
Q6IBS0 |
0.70 |
|
ARRB1 |
408 |
P49407 |
0.72 |
|
ARRB2 |
409 |
P32121 |
0.72 |
|
BRAF |
673 |
P15056 |
0.72 |
|
FN1 |
2335 |
P02751 |
0.72 |
|
GRB2 |
2885 |
P62993 |
0.72 |
|
H2AFX |
3014 |
P16104 |
0.72 |
|
PRICKLE3 |
4007 |
O43900 |
0.72 |
|
MYC |
4609 |
P01106 |
0.72 |
|
MYH11 |
4629 |
P35749 |
0.72 |
|
CDK16 |
5127 |
Q00536 |
0.72 |
|
CDK14 |
5218 |
O94921 |
0.72 |
|
MAP2K1 |
5604 |
Q02750 |
0.72 |
|
RAD52 |
5893 |
P43351 |
0.72 |
|
TSNAX |
7257 |
Q99598 |
0.72 |
|
IRS4 |
8471 |
O14654 |
0.72 |
|
TNK1 |
8711 |
Q13470 |
0.72 |
|
RASSF2 |
9770 |
P50749 |
0.72 |
|
RIPK3 |
11035 |
Q9Y572 |
0.72 |
|
MAST1 |
22983 |
Q9Y2H9 |
0.72 |
|
TAB2 |
23118 |
Q9NYJ8 |
0.72 |
|
EPB41L3 |
23136 |
Q9Y2J2 |
0.72 |
|
WWC1 |
23286 |
Q8IX03 |
0.72 |
|
DTL |
51514 |
Q9NZJ0 |
0.72 |
|
CCDC88A |
55704 |
Q3V6T2 |
0.72 |
|
SAV1 |
60485 |
Q9H4B6 |
0.72 |
|
LRFN4 |
78999 |
Q6PJG9 |
0.72 |
|
PARD6G |
84552 |
Q9BYG4 |
0.72 |
|
TPH2 |
121278 |
Q8IWU9 |
0.72 |
|
LCA5 |
167691 |
Q86VQ0 |
0.72 |
|
POLR3H |
171568 |
Q9Y535 |
0.72 |
|
ATIC |
471 |
P31939 |
0.73 |
|
PTPN14 |
5784 |
Q15678 |
0.73 |
|
FBXW11 |
23291 |
Q9UKB1 |
0.73 |
|
SRRM2 |
23524 |
Q9UQ35 |
0.73 |
|
POT1 |
25913 |
Q9NUX5 |
0.73 |
|
PAPOLA |
10914 |
P51003 |
0.74 |
|
CASP3 |
836 |
P42574 |
0.75 |
|
GRB10 |
2887 |
Q13322 |
0.75 |
|
ACD |
65057 |
Q96AP0 |
0.75 |
|
TSC1 |
7248 |
Q92574 |
0.76 |
|
CBX4 |
8535 |
O00257 |
0.76 |
|
USP43 |
124739 |
Q70EL4 |
0.76 |
|
FBXO4 |
26272 |
Q9UKT5 |
0.77 |
|
MLF1 |
4291 |
P58340 |
0.78 |
|
RIN1 |
9610 |
Q13671 |
0.78 |
|
PRKAA1 |
5562 |
Q13131 |
0.79 |
|
TFDP2 |
7029 |
Q14188 |
0.81 |
|
CBL |
867 |
P22681 |
0.82 |
|
MAPK7 |
5598 |
Q13164 |
0.82 |
|
VCAM1 |
7412 |
P19320 |
0.82 |
|
HDAC9 |
9734 |
Q9UKV0 |
0.82 |
|
GAB2 |
9846 |
Q9UQC2 |
0.82 |
|
YAP1 |
10413 |
P46937 |
0.82 |
|
SIK2 |
23235 |
Q9H0K1 |
0.82 |
|
SIK3 |
23387 |
Q9Y2K2 |
0.82 |
|
RICTOR |
253260 |
Q6R327 |
0.82 |
|
MARK2 |
2011 |
Q7KZI7 |
0.83 |
|
FOXO3 |
2309 |
O43524 |
0.83 |
|
ABL1 |
25 |
P00519 |
0.84 |
|
MST1R |
4486 |
Q04912 |
0.84 |
|
EXO1 |
9156 |
Q9UQ84 |
0.84 |
|
YWHAQ |
10971 |
P27348 |
0.84 |
|
TP53 |
7157 |
P04637 |
0.86 |
|
MDM4 |
4194 |
O15151 |
0.88 |
|
HIST1H3A |
8350 |
P68431 |
0.88 |
|
WWTR1 |
25937 |
Q9GZV5 |
0.88 |
|
LRRK2 |
120892 |
Q5S007 |
0.88 |
|
CDC25A |
993 |
P30304 |
0.89 |
|
MARK3 |
4140 |
P27448 |
0.89 |
|
HDAC7 |
51564 |
Q8WUI4 |
0.89 |
|
NDEL1 |
81565 |
Q9GZM8 |
0.89 |
|
MAP3K3 |
4215 |
Q99759 |
0.90 |
|
HDAC4 |
9759 |
P56524 |
0.90 |
|
HDAC5 |
10014 |
Q9UQL6 |
0.90 |
|
MAP3K2 |
10746 |
Q9Y2U5 |
0.90 |
|
YWHAB |
7529 |
P31946 |
0.94 |
|
YWHAZ |
7534 |
P63104 |
0.96 |