| Gene Symbol | WRB |
| Entrez ID | 7485 |
| Uniprot ID | O00258 |
| Description | tryptophan rich basic protein |
| Chromosomal Location | chr21: 39,380,244-39,428,528 |
| Ontology | GO ID | GO Term | Definition | Evidence |
|---|---|---|---|---|
|
BP |
GO:0071816 |
tail-anchored membrane protein insertion into ER membrane |
A process of protein insertion into the endoplasmic reticulum (ER) membrane in which a tail-anchored (TA) transmembrane protein is incorporated into an endoplasmic reticulum (ER) membrane. TA transmembrane protein, also named type II transmembrane proteins, contain a single C- terminal transmembrane region. |
IEA |
|
CC |
GO:0005634 |
nucleus |
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
TAS |
|
CC |
GO:0005789 |
endoplasmic reticulum membrane |
The lipid bilayer surrounding the endoplasmic reticulum. |
IEA |
|
CC |
GO:0016021 |
integral component of membrane |
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
IEA |
| Domain ID | Description |
|---|---|
|
IPR028945 |
WRB/Get1 family |
| UMLS CUI | UMLS Term |
|---|---|
|
C0013080 |
Down Syndrome |
|
C0151786 |
Muscle Weakness |
| Tissue | Cell Type |
|---|---|
|
adrenal gland |
glandular cells |
|
bronchus |
respiratory epithelial cells |
|
caudate |
neuronal cells |
|
cerebellum |
cells in granular layer |
|
cerebral cortex |
endothelial cells |
|
cerebral cortex |
neuronal cells |
|
cerebral cortex |
neuropil |
|
colon |
glandular cells |
|
duodenum |
glandular cells |
|
endometrium |
cells in endometrial stroma |
|
gallbladder |
glandular cells |
|
hippocampus |
neuronal cells |
|
liver |
hepatocytes |
|
nasopharynx |
respiratory epithelial cells |
|
placenta |
decidual cells |
|
rectum |
glandular cells |
|
skin |
melanocytes |
|
skin |
epidermal cells |
|
small intestine |
glandular cells |
|
soft tissue |
adipocytes |
|
stomach |
glandular cells |
|
testis |
cells in seminiferous ducts |
|
thyroid gland |
glandular cells |
|
tonsil |
squamous epithelial cells |
|
urinary bladder |
urothelial cells |
| Pubmed ID | Author | Year | Title |
|---|---|---|---|
|
23824412 |
Piltonen et al. |
2013 |
Mesenchymal Stem/Progenitors and Other Endometrial Cell Types From Women With Polycystic Ovary Syndrome (PCOS) Display Inflammatory and Oncogenic Potential |
| Gene Symbol | Entrez ID | Uniprot ID | Score |
|---|---|---|---|
|
FAS |
355 |
P25445 |
0.63 |
|
CAMLG |
819 |
P49069 |
0.63 |
|
SERPINA6 |
866 |
P08185 |
0.63 |
|
ITGB8 |
3696 |
P26012 |
0.63 |
|
LPAR6 |
10161 |
P43657 |
0.63 |
|
ERGIC3 |
51614 |
Q9Y282 |
0.63 |
|
MCOLN3 |
55283 |
Q8TDD5 |
0.63 |
|
DPEP2 |
64174 |
Q9H4A9 |
0.63 |
|
TOR3A |
64222 |
Q9H497 |
0.63 |
|
CNDP1 |
84735 |
Q96KN2 |
0.63 |
|
HTR3C |
170572 |
Q8WXA8 |
0.63 |