Protein Description

Gene Symbol UGCG
Entrez ID 7357
Uniprot ID Q16739
Description UDP-glucose ceramide glucosyltransferase
Chromosomal Location chr9: 111,896,766-111,935,369
Ontology GO ID GO Term Definition Evidence

BP

GO:0006679

glucosylceramide biosynthetic process

The chemical reactions and pathways resulting in the formation of glucosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of glucose by a ceramide group.

TAS

BP

GO:0006687

glycosphingolipid metabolic process

The chemical reactions and pathways involving glycosphingolipids, any compound with residues of sphingoid and at least one monosaccharide.

TAS

BP

GO:0006688

glycosphingolipid biosynthetic process

The chemical reactions and pathways resulting in the formation of glycosphingolipid, a compound with residues of sphingoid and at least one monosaccharide.

TAS

BP

GO:0008544

epidermis development

The process whose specific outcome is the progression of the epidermis over time, from its formation to the mature structure. The epidermis is the outer epithelial layer of an animal, it may be a single layer that produces an extracellular material (e.g. the cuticle of arthropods) or a complex stratified squamous epithelium, as in the case of many vertebrate species.

TAS

BP

GO:1903955

positive regulation of protein targeting to mitochondrion

Any process that activates or increases the frequency, rate or extent of protein targeting to mitochondrion.

IMP

CC

GO:0000139

Golgi membrane

The lipid bilayer surrounding any of the compartments of the Golgi apparatus.

TAS

CC

GO:0016020

membrane

A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.

TAS

CC

GO:0016021

integral component of membrane

The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

IEA

MF

GO:0008120

ceramide glucosyltransferase activity

Catalysis of the reaction: UDP-glucose + N-acylsphingosine = UDP + D-glucosyl-N-acylsphingosine.

TAS

Domain ID Description

IPR025993

Ceramide glucosyltransferase

IPR029044

Nucleotide-diphospho-sugar transferases

Pathway ID Pathway Term Pathway Source

hsa00600

Sphingolipid metabolism

KEGG

hsa01100

Metabolic pathways

KEGG

UMLS CUI UMLS Term

C0017661

Iga Glomerulonephritis

C0151744

Myocardial Ischemia

Tissue Cell Type

kidney

cells in tubules

liver

hepatocytes

tonsil

non-germinal center cells

No databases found.

Pubmed ID Author Year Title

22617121

Ouandaogo et al.

2012

Differences in transcriptomic profiles of human cumulus cells isolated from oocytes at GV, MI and MII stages after in vivo andin vitro oocyte maturation

Gene Symbol Entrez ID Uniprot ID Score

APP

351

P05067

0.56

RTN1

6252

Q16799

0.86

TNFRSF10B

8795

O14763

0.63

PICK1

9463

Q9NRD5

0.63

TSPAN3

10099

O60637

0.63

RTN3

10313

O95197

0.63

TMEM231

79583

Q9H6L2

0.63

HEPACAM2

253012

A8MVW5

0.63

CHMP4B

128866

Q9H444

0.72