Gene Symbol | UGCG |
Entrez ID | 7357 |
Uniprot ID | Q16739 |
Description | UDP-glucose ceramide glucosyltransferase |
Chromosomal Location | chr9: 111,896,766-111,935,369 |
Ontology | GO ID | GO Term | Definition | Evidence |
---|---|---|---|---|
BP |
GO:0006679 |
glucosylceramide biosynthetic process |
The chemical reactions and pathways resulting in the formation of glucosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of glucose by a ceramide group. |
TAS |
BP |
GO:0006687 |
glycosphingolipid metabolic process |
The chemical reactions and pathways involving glycosphingolipids, any compound with residues of sphingoid and at least one monosaccharide. |
TAS |
BP |
GO:0006688 |
glycosphingolipid biosynthetic process |
The chemical reactions and pathways resulting in the formation of glycosphingolipid, a compound with residues of sphingoid and at least one monosaccharide. |
TAS |
BP |
GO:0008544 |
epidermis development |
The process whose specific outcome is the progression of the epidermis over time, from its formation to the mature structure. The epidermis is the outer epithelial layer of an animal, it may be a single layer that produces an extracellular material (e.g. the cuticle of arthropods) or a complex stratified squamous epithelium, as in the case of many vertebrate species. |
TAS |
BP |
GO:1903955 |
positive regulation of protein targeting to mitochondrion |
Any process that activates or increases the frequency, rate or extent of protein targeting to mitochondrion. |
IMP |
CC |
GO:0000139 |
Golgi membrane |
The lipid bilayer surrounding any of the compartments of the Golgi apparatus. |
TAS |
CC |
GO:0016020 |
membrane |
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it. |
TAS |
CC |
GO:0016021 |
integral component of membrane |
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
IEA |
MF |
GO:0008120 |
ceramide glucosyltransferase activity |
Catalysis of the reaction: UDP-glucose + N-acylsphingosine = UDP + D-glucosyl-N-acylsphingosine. |
TAS |
Domain ID | Description |
---|---|
IPR025993 |
Ceramide glucosyltransferase |
IPR029044 |
Nucleotide-diphospho-sugar transferases |
Pathway ID | Pathway Term | Pathway Source |
---|---|---|
hsa00600 |
Sphingolipid metabolism |
KEGG |
hsa01100 |
Metabolic pathways |
KEGG |
UMLS CUI | UMLS Term |
---|---|
C0017661 |
Iga Glomerulonephritis |
C0151744 |
Myocardial Ischemia |
Tissue | Cell Type |
---|---|
kidney |
cells in tubules |
liver |
hepatocytes |
tonsil |
non-germinal center cells |
Pubmed ID | Author | Year | Title |
---|---|---|---|
22617121 |
Ouandaogo et al. |
2012 |
Differences in transcriptomic profiles of human cumulus cells isolated from oocytes at GV, MI and MII stages after in vivo andin vitro oocyte maturation |
Gene Symbol | Entrez ID | Uniprot ID | Score |
---|---|---|---|
APP |
351 |
P05067 |
0.56 |
RTN1 |
6252 |
Q16799 |
0.86 |
TNFRSF10B |
8795 |
O14763 |
0.63 |
PICK1 |
9463 |
Q9NRD5 |
0.63 |
TSPAN3 |
10099 |
O60637 |
0.63 |
RTN3 |
10313 |
O95197 |
0.63 |
TMEM231 |
79583 |
Q9H6L2 |
0.63 |
HEPACAM2 |
253012 |
A8MVW5 |
0.63 |
CHMP4B |
128866 |
Q9H444 |
0.72 |