Gene Symbol | TNFAIP6 |
Entrez ID | 7130 |
Uniprot ID | P98066 |
Description | TNF alpha induced protein 6 |
Chromosomal Location | chr2: 151,357,592-151,380,048 |
Ontology | GO ID | GO Term | Definition | Evidence |
---|---|---|---|---|
BP |
GO:0006954 |
inflammatory response |
The immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The process is characterized by local vasodilation, extravasation of plasma into intercellular spaces and accumulation of white blood cells and macrophages. |
TAS |
BP |
GO:0007155 |
cell adhesion |
The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules. |
IEA |
BP |
GO:0007165 |
signal transduction |
The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell. |
TAS |
BP |
GO:0007267 |
cell-cell signaling |
Any process that mediates the transfer of information from one cell to another. This process includes signal transduction in the receiving cell and, where applicable, release of a ligand and any processes that actively facilitate its transport and presentation to the receiving cell. Examples include signaling via soluble ligands, via cell adhesion molecules and via gap junctions. |
TAS |
BP |
GO:0030335 |
positive regulation of cell migration |
Any process that activates or increases the frequency, rate or extent of cell migration. |
IEA |
BP |
GO:0030728 |
ovulation |
The release of a mature ovum/oocyte from an ovary. |
IEA |
BP |
GO:0050728 |
negative regulation of inflammatory response |
Any process that stops, prevents, or reduces the frequency, rate or extent of the inflammatory response. |
IDA |
CC |
GO:0005615 |
extracellular space |
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid. |
IEA |
MF |
GO:0005515 |
protein binding |
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules). |
IPI |
MF |
GO:0005540 |
hyaluronic acid binding |
Interacting selectively and non-covalently with hyaluronic acid, a polymer composed of repeating dimeric units of glucuronic acid and N-acetyl glucosamine. |
IEA |
Domain ID | Description |
---|---|
IPR000538 |
Link domain |
IPR000859 |
CUB domain |
IPR016186 |
C-type lectin-like/link domain |
IPR016187 |
C-type lectin fold |
UMLS CUI | UMLS Term |
---|---|
C0021400 |
Influenza |
C0037274 |
Dermatologic Disorders |
C0162820 |
Dermatitis, Allergic Contact |
C0311375 |
Arsenic Poisoning |
C0740392 |
Infarction, Middle Cerebral Artery |
C3495559 |
Juvenile Arthritis |
Pubmed ID | Author | Year | Title |
---|---|---|---|
22344199 |
Chazenbalk et al. |
2012 |
Abnormal Expression of Genes Involved in Inflammation, Lipid Metabolism, and Wnt Signaling in the Adipose Tissue of Polycystic Ovary Syndrome |
22617121 |
Ouandaogo et al. |
2012 |
Differences in transcriptomic profiles of human cumulus cells isolated from oocytes at GV, MI and MII stages after in vivo andin vitro oocyte maturation |
22951915 |
Haozi et al. |
2012 |
Altered gene expression profile in cumulus cells of mature MII oocytes from patients with polycystic ovary syndrome |
23824412 |
Piltonen et al. |
2013 |
Mesenchymal Stem/Progenitors and Other Endometrial Cell Types From Women With Polycystic Ovary Syndrome (PCOS) Display Inflammatory and Oncogenic Potential |
25393639 |
Ambekar et al. |
2014 |
Proteomics of follicular fluid from women with polycystic ovary syndrome suggests molecular defects in follicular development |
Gene Symbol | Entrez ID | Uniprot ID | Score |
---|---|---|---|
THBS1 |
7057 |
P07996 |
0.52 |
ACAN |
176 |
P16112 |
0.75 |