Protein Description

Gene Symbol TMPO
Entrez ID 7112
Uniprot ID P42166
Description thymopoietin
Chromosomal Location chr12: 98,515,512-98,550,379
Ontology GO ID GO Term Definition Evidence

BP

GO:0006355

regulation of transcription, DNA-templated

Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.

IEA

BP

GO:0098609

cell-cell adhesion

The attachment of one cell to another cell via adhesion molecules.

IEA

CC

GO:0000785

chromatin

The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome.

IDA

CC

GO:0005634

nucleus

A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

IDA

CC

GO:0005635

nuclear envelope

The double lipid bilayer enclosing the nucleus and separating its contents from the rest of the cytoplasm; includes the intermembrane space, a gap of width 20-40 nm (also called the perinuclear space).

TAS

CC

GO:0005637

nuclear inner membrane

The inner, i.e. lumen-facing, lipid bilayer of the nuclear envelope.

IEA

CC

GO:0005789

endoplasmic reticulum membrane

The lipid bilayer surrounding the endoplasmic reticulum.

IEA

CC

GO:0005913

cell-cell adherens junction

An adherens junction which connects a cell to another cell.

IDA

MF

GO:0003677

DNA binding

Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).

IEA

MF

GO:0005521

lamin binding

Interacting selectively and non-covalently with lamin; any of a group of intermediate-filament proteins that form the fibrous matrix on the inner surface of the nuclear envelope.

TAS

MF

GO:0098641

cadherin binding involved in cell-cell adhesion

Any cadherin binding that occurs as part of the process of cell-cell adhesion.

IDA

Domain ID Description

IPR003887

LEM domain

IPR011015

LEM/LEM-like domain

IPR013146

LEM-like domain

IPR021623

Lamina-associated polypeptide 2 alpha

No pathways found.

UMLS CUI UMLS Term

C0003873

Rheumatoid Arthritis

C0007193

Cardiomyopathy, Dilated

C0017661

Iga Glomerulonephritis

C0151744

Myocardial Ischemia

Tissue Cell Type

appendix

glandular cells

appendix

lymphoid tissue

bone marrow

hematopoietic cells

bronchus

respiratory epithelial cells

cerebral cortex

neuronal cells

cervix, uterine

glandular cells

cervix, uterine

squamous epithelial cells

colon

endothelial cells

colon

glandular cells

duodenum

glandular cells

endometrium

cells in endometrial stroma

endometrium

glandular cells

esophagus

squamous epithelial cells

fallopian tube

glandular cells

lung

pneumocytes

lymph node

germinal center cells

lymph node

non-germinal center cells

nasopharynx

respiratory epithelial cells

oral mucosa

squamous epithelial cells

prostate

glandular cells

rectum

glandular cells

skin

fibroblasts

skin

keratinocytes

skin

Langerhans

skin

melanocytes

skin

epidermal cells

small intestine

glandular cells

spleen

cells in red pulp

spleen

cells in white pulp

stomach

glandular cells

tonsil

germinal center cells

tonsil

non-germinal center cells

vagina

squamous epithelial cells

No databases found.

Pubmed ID Author Year Title

22617121

Ouandaogo et al.

2012

Differences in transcriptomic profiles of human cumulus cells isolated from oocytes at GV, MI and MII stages after in vivo andin vitro oocyte maturation

Gene Symbol Entrez ID Uniprot ID Score

MRE11A

4361

P49959

0.49

LARS

51520

Q9P2J5

0.49

ATRX

546

P46100

0.63

BST2

684

Q10589

0.63

CHD1

1105

O14646

0.63

STOM

2040

P27105

0.63

HSPG2

3339

P98160

0.63

LIG3

3980

P49916

0.63

PHB

5245

P35232

0.63

RRBP1

6238

Q9P2E9

0.63

SDC2

6383

P34741

0.63

SUPT6H

6830

Q7KZ85

0.63

TUBG1

7283

P23258

0.63

UBTF

7343

P17480

0.63

VARS

7407

P26640

0.63

PCGF2

7703

P35227

0.63

MLLT10

8028

P55197

0.63

HIST1H2BC; HIST1H2BE; HIST1H2BF; HIST1H2BG; HIST1H2BI

8339

P62807

0.63

HIRIP3

8479

Q9BW71

0.63

ATP6V0D1

9114

P61421

0.63

NOLC1

9221

Q14978

0.63

KAT7

11143

O95251

0.63

RPL35

11224

P42766

0.63

PHB2

11331

Q99623

0.63

EXOSC8

11340

Q96B26

0.63

BRD1

23774

O95696

0.63

NUSAP1

51203

Q9BXS6

0.63

PHIP

55023

Q8WWQ0

0.63

JADE1

79960

Q6IE81

0.63

LMNB2

84823

Q03252

0.63

PRKCDBP

112464

Q969G5

0.63

SGMS2

166929

Q8NHU3

0.63

OIP5

11339

O43482

0.72

HDAC3

8841

O15379

0.75

RB1

5925

P06400

0.83

USP7

7874

Q93009

0.86

LMNA

4000

P02545

0.89

LMNB1

4001

P20700

0.89

CIRBP

1153

Q14011

0.49

ILF3

3609

Q12906

0.49

PXN

5829

P49023

0.49

MESDC2

23184

Q14696

0.49

NUP160

23279

Q12769

0.49

TCTN3

26123

Q6NUS6

0.49

HP1BP3

50809

Q5SSJ5

0.49

TMEM216

51259

Q9P0N5

0.49

NUP133

55746

Q8WUM0

0.49

TCTN2

79867

Q96GX1

0.49

NUP35

129401

Q8NFH5

0.49

CLK1

1195

P49759

0.52

CSNK2A1

1457

P68400

0.52

SRPK2

6733

P78362

0.52

SGTB

54557

Q96EQ0

0.52

PFKP

5214

Q01813

0.59

SGTA

6449

O43765

0.62

GMCL1

64395

Q96IK5

0.62

FMNL1

752

O95466

0.63

CD81

975

P60033

0.63

CDC5L

988

Q99459

0.63

CLN3

1201

Q13286

0.63

CRY2

1408

Q49AN0

0.63

JUN

3725

P05412

0.63

LGALS3

3958

P17931

0.63

MDM2

4193

Q00987

0.63

NTRK1

4914

P04629

0.63

MAPK13

5603

O15264

0.63

RAD21

5885

O60216

0.63

ABCE1

6059

P61221

0.63

RPA1

6117

P27694

0.63

RPA2

6118

P15927

0.63

RPA3

6119

P35244

0.63

SUMO3

6612

P55854

0.63

TP53BP1

7158

Q12888

0.63

SUMO1

7341

P63165

0.63

VCAM1

7412

P19320

0.63

WHSC1

7468

O96028

0.63

XRCC3

7517

O43542

0.63

YWHAE

7531

P62258

0.63

HIST1H3A

8350

P68431

0.63

EED

8726

O75530

0.63

MED26

9441

O95402

0.63

HDAC9

9734

Q9UKV0

0.63

CUL7

9820

Q14999

0.63

PTBP3

9991

O95758

0.63

ZWINT

11130

O95229

0.63

AP4S1

11154

Q9Y587

0.63

SNW1

22938

Q13573

0.63

PAXIP1

22976

Q6ZW49

0.63

OBSL1

23363

O75147

0.63

FBXO6

26270

Q9NRD1

0.63

MED9

55090

Q9NWA0

0.63

TMEM63B

55362

Q5T3F8

0.63

MED29

55588

Q9NX70

0.63

SMARCAD1

56916

Q9H4L7

0.63

SMURF1

57154

Q9HCE7

0.63

HDAC11

79885

Q96DB2

0.63

SPRTN

83932

Q9H040

0.63

CCDC8

83987

Q9H0W5

0.63

UNK

85451

Q9C0B0

0.63

RNF185

91445

Q96GF1

0.63

LRRK2

120892

Q5S007

0.63

PYHIN1

149628

Q6K0P9

0.63

MED19

219541

A0JLT2

0.63

SCARNA22

677770

N/A

0.63

SMN1; SMN2

6606

Q16637

0.63

ARRB1

408

P49407

0.72

ARRB2

409

P32121

0.72

HDGF

3068

P51858

0.72

MYC

4609

P01106

0.72

XRCC5

7520

P13010

0.72

FYCO1

79443

Q9BQS8

0.72

SUMO2

6613

P61956

0.79

BANF1

8815

O75531

0.88

AKAP8L

26993

Q9ULX6

0.89