| Gene Symbol | TCEA3 |
| Entrez ID | 6920 |
| Uniprot ID | O75764 |
| Description | transcription elongation factor A (SII), 3 |
| Chromosomal Location | chr1: 23,381,061-23,424,740 |
| Ontology | GO ID | GO Term | Definition | Evidence |
|---|---|---|---|---|
|
BP |
GO:0006351 |
transcription, DNA-templated |
The cellular synthesis of RNA on a template of DNA. |
IEA |
|
BP |
GO:0006357 |
regulation of transcription from RNA polymerase II promoter |
Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter. |
IEA |
|
BP |
GO:0032784 |
regulation of DNA-templated transcription, elongation |
Any process that modulates the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides catalyzed by a DNA-dependent RNA polymerase. |
IEA |
|
CC |
GO:0005634 |
nucleus |
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
IEA |
|
MF |
GO:0003677 |
DNA binding |
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). |
IEA |
|
MF |
GO:0008270 |
zinc ion binding |
Interacting selectively and non-covalently with zinc (Zn) ions. |
IEA |
| Domain ID | Description |
|---|---|
|
IPR001222 |
Zinc finger, TFIIS-type |
|
IPR003617 |
Transcription elongation factor, TFIIS/CRSP70, N-terminal, sub-type |
|
IPR003618 |
Transcription elongation factor S-II, central domain |
|
IPR006289 |
Transcription elongation factor, TFIIS |
|
IPR017923 |
Transcription factor IIS, N-terminal |
| Tissue | Cell Type |
|---|---|
|
appendix |
glandular cells |
|
bone marrow |
hematopoietic cells |
|
bronchus |
respiratory epithelial cells |
|
cerebellum |
Purkinje cells |
|
cerebral cortex |
endothelial cells |
|
cervix, uterine |
glandular cells |
|
cervix, uterine |
squamous epithelial cells |
|
colon |
glandular cells |
|
duodenum |
glandular cells |
|
endometrium |
glandular cells |
|
esophagus |
squamous epithelial cells |
|
gallbladder |
glandular cells |
|
heart muscle |
myocytes |
|
hippocampus |
neuronal cells |
|
liver |
hepatocytes |
|
nasopharynx |
respiratory epithelial cells |
|
pancreas |
exocrine glandular cells |
|
rectum |
glandular cells |
|
salivary gland |
glandular cells |
|
skeletal muscle |
myocytes |
|
skin |
epidermal cells |
|
smooth muscle |
smooth muscle cells |
|
stomach |
glandular cells |
|
thyroid gland |
glandular cells |
|
tonsil |
squamous epithelial cells |
|
vagina |
squamous epithelial cells |
| Pubmed ID | Author | Year | Title |
|---|---|---|---|
|
22617121 |
Ouandaogo et al. |
2012 |
Differences in transcriptomic profiles of human cumulus cells isolated from oocytes at GV, MI and MII stages after in vivo andin vitro oocyte maturation |
|
22951915 |
Haozi et al. |
2012 |
Altered gene expression profile in cumulus cells of mature MII oocytes from patients with polycystic ovary syndrome |
| Gene Symbol | Entrez ID | Uniprot ID | Score |
|---|---|---|---|
|
RPH3AL |
9501 |
Q9UNE2 |
0.63 |