Gene Symbol | TACC1 |
Entrez ID | 6867 |
Uniprot ID | O75410 |
Description | transforming, acidic coiled-coil containing protein 1 |
Chromosomal Location | chr8: 38,728,186-38,853,028 |
Ontology | GO ID | GO Term | Definition | Evidence |
---|---|---|---|---|
BP |
GO:0000226 |
microtubule cytoskeleton organization |
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins. |
IBA |
BP |
GO:0007049 |
cell cycle |
The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division. |
IEA |
BP |
GO:0008283 |
cell proliferation |
The multiplication or reproduction of cells, resulting in the expansion of a cell population. |
IBA |
BP |
GO:0021987 |
cerebral cortex development |
The progression of the cerebral cortex over time from its initial formation until its mature state. The cerebral cortex is the outer layered region of the telencephalon. |
IBA |
BP |
GO:0051301 |
cell division |
The process resulting in division and partitioning of components of a cell to form more cells; may or may not be accompanied by the physical separation of a cell into distinct, individually membrane-bounded daughter cells. |
IEA |
CC |
GO:0005634 |
nucleus |
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
IEA |
CC |
GO:0005737 |
cytoplasm |
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
IBA|IDA |
CC |
GO:0005815 |
microtubule organizing center |
An intracellular structure that can catalyze gamma-tubulin-dependent microtubule nucleation and that can anchor microtubules by interacting with their minus ends, plus ends or sides. |
IEA |
CC |
GO:0015630 |
microtubule cytoskeleton |
The part of the cytoskeleton (the internal framework of a cell) composed of microtubules and associated proteins. |
IBA|IDA |
CC |
GO:0016020 |
membrane |
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it. |
IEA |
CC |
GO:0030496 |
midbody |
A thin cytoplasmic bridge formed between daughter cells at the end of cytokinesis. The midbody forms where the contractile ring constricts, and may persist for some time before finally breaking to complete cytokinesis. |
IEA |
CC |
GO:0045111 |
intermediate filament cytoskeleton |
Cytoskeletal structure made from intermediate filaments, typically organized in the cytosol as an extended system that stretches from the nuclear envelope to the plasma membrane. Some intermediate filaments run parallel to the cell surface, while others traverse the cytosol; together they form an internal framework that helps support the shape and resilience of the cell. |
IDA |
MF |
GO:0005515 |
protein binding |
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules). |
IPI |
Domain ID | Description |
---|---|
IPR007707 |
Transforming acidic coiled-coil-containing protein |
UMLS CUI | UMLS Term |
---|---|
C0206726 |
Gliosarcoma |
C0334588 |
Giant Cell Glioblastoma |
Tissue | Cell Type |
---|---|
bone marrow |
hematopoietic cells |
bronchus |
respiratory epithelial cells |
colon |
glandular cells |
colon |
peripheral nerve/ganglion |
fallopian tube |
glandular cells |
gallbladder |
glandular cells |
lung |
macrophages |
pancreas |
exocrine glandular cells |
placenta |
decidual cells |
placenta |
trophoblastic cells |
rectum |
glandular cells |
testis |
cells in seminiferous ducts |
Pubmed ID | Author | Year | Title |
---|---|---|---|
17148555 |
Wood et al. |
2007 |
Molecular Abnormalities in Oocytes from Women with Polycystic Ovary Syndrome Revealed by Microarray Analysis |
22617121 |
Ouandaogo et al. |
2012 |
Differences in transcriptomic profiles of human cumulus cells isolated from oocytes at GV, MI and MII stages after in vivo andin vitro oocyte maturation |
Gene Symbol | Entrez ID | Uniprot ID | Score |
---|---|---|---|
BTRC |
8945 |
Q9Y297 |
0.63 |
TACC2 |
10579 |
O95359 |
0.63 |
SH2D4A |
63898 |
Q9H788 |
0.63 |
TACC1 |
6867 |
O75410 |
0.67 |
LYST |
1130 |
Q99698 |
0.72 |
BRD3 |
8019 |
Q15059 |
0.72 |
RB1CC1 |
9821 |
Q8TDY2 |
0.72 |
BAIAP2L1 |
55971 |
Q9UHR4 |
0.72 |
AURKB |
9212 |
Q96GD4 |
0.77 |
YEATS4 |
8089 |
O95619 |
0.78 |
SNRPG |
6637 |
P62308 |
0.89 |
LSM7 |
51690 |
Q9UK45 |
0.89 |
CKAP5 |
9793 |
Q14008 |
0.90 |
S100A11 |
6282 |
P31949 |
0.49 |
SLC9A3R1 |
9368 |
O14745 |
0.49 |
PLXNB2 |
23654 |
O15031 |
0.49 |
NIF3L1 |
60491 |
Q9GZT8 |
0.49 |
C12orf57 |
113246 |
Q99622 |
0.49 |
KAT2A |
2648 |
Q92830 |
0.59 |
THAP12 |
5612 |
O43422 |
0.63 |
STX5 |
6811 |
Q13190 |
0.63 |
VAPB |
9217 |
O95292 |
0.63 |
ITSN2 |
50618 |
Q9NZM3 |
0.63 |
DTNBP1 |
84062 |
Q96EV8 |
0.63 |
BARD1 |
580 |
Q99728 |
0.72 |
VAPA |
9218 |
Q9P0L0 |
0.72 |
KDM1A |
23028 |
O60341 |
0.72 |
HTT |
3064 |
P42858 |
0.73 |
FBXW11 |
23291 |
Q9UKB1 |
0.73 |
MEMO1 |
51072 |
Q9Y316 |
0.73 |
TDRD7 |
23424 |
Q8NHU6 |
0.79 |
AURKA |
6790 |
O14965 |
0.88 |