Protein Description

Gene Symbol SSR4
Entrez ID 6748
Uniprot ID P51571
Description signal sequence receptor, delta
Chromosomal Location chrX: 153,793,516-153,798,505
Ontology GO ID GO Term Definition Evidence

CC

GO:0005784

Sec61 translocon complex

A translocon complex that contains a core heterotrimer of conserved alpha, beta and gamma subunits, and may contain additional proteins (translocon-associated proteins or TRAPs); in budding yeast the core proteins are Sec61p, Sbh1p, and Sss1p. The Sec61 translocon complex functions in cotranslational and posttranslational translocation events.

NAS

CC

GO:0016021

integral component of membrane

The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

IEA

CC

GO:0070062

extracellular exosome

A membrane-bounded vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.

IDA

Domain ID Description

IPR008855

Translocon-associated

Pathway ID Pathway Term Pathway Source

hsa04141

Protein processing in endoplasmic reticulum

KEGG

No diseases found.

Tissue Cell Type

bone marrow

hematopoietic cells

cerebellum

Purkinje cells

pancreas

exocrine glandular cells

placenta

decidual cells

salivary gland

glandular cells

seminal vesicle

glandular cells

stomach

glandular cells

No databases found.

Pubmed ID Author Year Title

22951915

Haozi et al.

2012

Altered gene expression profile in cumulus cells of mature MII oocytes from patients with polycystic ovary syndrome

Gene Symbol Entrez ID Uniprot ID Score

KDSR

2531

Q06136

0.49

RPN2

6185

P04844

0.49

CCT7

10574

Q99832

0.49

TIMM10

26519

P62072

0.49

ARL8B

55207

Q9NVJ2

0.49

IPO9

55705

Q96P70

0.49

NCLN

56926

Q969V3

0.49

MAGT1

84061

Q9H0U3

0.49

POMP

51371

Q9Y244

0.63

WRAP73

49856

Q9P2S5

0.72

ATP5A1

498

P25705

0.49

ATP5C1

509

P36542

0.49

CDH2

1000

P19022

0.49

COX4I1

1327

P13073

0.49

CTSV

1515

O60911

0.49

ECE1

1889

P42892

0.49

HSP90AA1

3320

P07900

0.49

HSP90AB1

3326

P08238

0.49

ILF2

3608

Q12905

0.49

ILF3

3609

Q12906

0.49

RPSA

3921

P08865

0.49

MT-CO2

4513

P00403

0.49

SLC25A3

5250

Q00325

0.49

RAB2A

5862

P61019

0.49

RPN1

6184

P04843

0.49

SCD

6319

O00767

0.49

SFPQ

6421

P23246

0.49

SNRPD3

6634

P62318

0.49

UQCRC2

7385

P22695

0.49

SUCLA2

8803

Q9P2R7

0.49

VAPB

9217

O95292

0.49

PPT2

9374

Q9UMR5

0.49

TECR

9524

Q9NZ01

0.49

NENF

29937

Q9UMX5

0.49

TOMM22

56993

Q9NS69

0.49

PRKCDBP

112464

Q969G5

0.49

SSR3

6747

Q9UNL2

0.52

PTEN

5728

P60484

0.56

DDOST

1650

P39656

0.59

ADRB2

154

P07550

0.63

ARF6

382

P62330

0.63

BMI1

648

P35226

0.63

CASP4

837

P49662

0.63

CDK2

1017

P24941

0.63

CLN3

1201

Q13286

0.63

EGFR

1956

P00533

0.63

HLA-A

3105

P30457

0.63

JUN

3725

P05412

0.63

MCM2

4171

P49736

0.63

NOS2

4843

P35228

0.63

PHKG2

5261

P15735

0.63

PRKAB1

5564

Q9Y478

0.63

CUL5

8065

Q93034

0.63

UBL4A

8266

P11441

0.63

CUL3

8452

Q13618

0.63

TNFRSF14

8764

Q92956

0.63

TSC22D1

8848

Q15714

0.63

HUWE1

10075

Q7Z6Z7

0.63

EIF1B

10289

O60739

0.63

GIPC1

10755

O14908

0.63

COPS5

10987

Q92905

0.63

PTP4A3

11156

O75365

0.63

GABARAP

11337

O95166

0.63

GABARAPL2

11345

P60520

0.63

SUZ12

23512

Q15022

0.63

CDK20

23552

Q8IZL9

0.63

GABARAPL1

23710

Q9H0R8

0.63

FBXO6

26270

Q9NRD1

0.63

AGO2

27161

Q9UKV8

0.63

TMBIM4

51643

Q9HC24

0.63

ASB1

51665

Q9Y576

0.63

OTUB1

55611

Q96FW1

0.63

CAND1

55832

Q86VP6

0.63

CBWD1

55871

Q9BRT8

0.63

MAP1LC3A

84557

Q9H492

0.63

LRRK2

120892

Q5S007

0.63

ASB17

127247

Q8WXJ9

0.63

ASB14

142686

A6NK59

0.63

HIPK4

147746

Q8NE63

0.63

MAP3K1

4214

Q13233

0.72

MME

4311

P08473

0.72

MYC

4609

P01106

0.72

SOD1

6647

P00441

0.72

TNFRSF1A

7132

P19438

0.72

TNFRSF1B

7133

P20333

0.72

AATK

9625

Q6ZMQ8

0.72

MAD2L2

10459

Q9UI95

0.72

TUBA1C

84790

Q9BQE3

0.72

SSR1

6745

P43307

0.73

RIOK3

8780

O14730

0.76

PHLDA3

23612

Q9Y5J5

0.76

C20orf24

55969

Q9BUV8

0.76

ILK

3611

Q13418

0.82

HECW1

23072

Q76N89

0.86