| Gene Symbol | SSB |
| Entrez ID | 6741 |
| Uniprot ID | P05455 |
| Description | Sjogren syndrome antigen B |
| Chromosomal Location | chr2: 169,791,933-169,812,064 |
| Ontology | GO ID | GO Term | Definition | Evidence |
|---|---|---|---|---|
|
BP |
GO:0006400 |
tRNA modification |
The covalent alteration of one or more nucleotides within a tRNA molecule to produce a tRNA molecule with a sequence that differs from that coded genetically. |
TAS |
|
BP |
GO:0008334 |
histone mRNA metabolic process |
The chemical reactions and pathways involving an mRNA encoding a histone. |
TAS |
|
BP |
GO:0075522 |
IRES-dependent viral translational initiation |
Process by which viral mRNA translation is initiated, where a domain in the 5' untranslated region (UTR) of the viral mRNA called an internal ribosome entry site (IRES) binds the host 43S preinitiation complex, circumventing regular cap-dependent translation initiation. |
IDA |
|
BP |
GO:1903608 |
protein localization to cytoplasmic stress granule |
A process in which a protein is transported to, or maintained in, a location within a cytoplasmic stress granule. |
IDA |
|
CC |
GO:0000784 |
nuclear chromosome, telomeric region |
The terminal region of a linear nuclear chromosome that includes the telomeric DNA repeats and associated proteins. |
IDA |
|
CC |
GO:0005634 |
nucleus |
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
IDA |
|
CC |
GO:0030529 |
intracellular ribonucleoprotein complex |
An intracellular macromolecular complex containing both protein and RNA molecules. |
IEA |
|
MF |
GO:0000049 |
tRNA binding |
Interacting selectively and non-covalently with transfer RNA. |
TAS |
|
MF |
GO:0000166 |
nucleotide binding |
Interacting selectively and non-covalently with a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose or deoxyribose. |
IEA |
|
MF |
GO:0003729 |
mRNA binding |
Interacting selectively and non-covalently with messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns. |
TAS |
|
MF |
GO:0005515 |
protein binding |
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules). |
IPI |
|
MF |
GO:0044822 |
poly(A) RNA binding |
Interacting non-covalently with a poly(A) RNA, a RNA molecule which has a tail of adenine bases. |
IDA |
| Domain ID | Description |
|---|---|
|
IPR000504 |
RNA recognition motif domain |
|
IPR002344 |
Lupus La protein |
|
IPR006630 |
RNA-binding protein Lupus La |
|
IPR011991 |
Winged helix-turn-helix DNA-binding domain |
|
IPR014886 |
La protein, RNA-binding domain |
| Pathway ID | Pathway Term | Pathway Source |
|---|---|---|
|
hsa05322 |
Systemic lupus erythematosus |
KEGG |
|
h_RNApol3Pathway |
RNA polymerase III transcription |
BioCarta |
| Tissue | Cell Type |
|---|---|
|
adrenal gland |
glandular cells |
|
appendix |
glandular cells |
|
breast |
glandular cells |
|
bronchus |
respiratory epithelial cells |
|
caudate |
glial cells |
|
cerebellum |
cells in granular layer |
|
cerebellum |
cells in molecular layer |
|
cerebellum |
Purkinje cells |
|
cerebral cortex |
glial cells |
|
cerebral cortex |
neuronal cells |
|
cervix, uterine |
glandular cells |
|
cervix, uterine |
squamous epithelial cells |
|
colon |
glandular cells |
|
endometrium |
glandular cells |
|
epididymis |
glandular cells |
|
esophagus |
squamous epithelial cells |
|
fallopian tube |
glandular cells |
|
gallbladder |
glandular cells |
|
hippocampus |
glial cells |
|
kidney |
cells in glomeruli |
|
kidney |
cells in tubules |
|
liver |
bile duct cells |
|
liver |
hepatocytes |
|
lung |
macrophages |
|
lung |
pneumocytes |
|
nasopharynx |
respiratory epithelial cells |
|
oral mucosa |
squamous epithelial cells |
|
ovary |
ovarian stroma cells |
|
pancreas |
exocrine glandular cells |
|
pancreas |
islets of Langerhans |
|
parathyroid gland |
glandular cells |
|
placenta |
decidual cells |
|
placenta |
trophoblastic cells |
|
prostate |
glandular cells |
|
rectum |
glandular cells |
|
salivary gland |
glandular cells |
|
seminal vesicle |
glandular cells |
|
skin |
epidermal cells |
|
small intestine |
glandular cells |
|
spleen |
cells in red pulp |
|
stomach |
glandular cells |
|
testis |
cells in seminiferous ducts |
|
testis |
Leydig cells |
|
thyroid gland |
glandular cells |
|
tonsil |
non-germinal center cells |
|
tonsil |
squamous epithelial cells |
|
urinary bladder |
urothelial cells |
|
vagina |
squamous epithelial cells |
| Pubmed ID | Author | Year | Title |
|---|---|---|---|
|
22951915 |
Haozi et al. |
2012 |
Altered gene expression profile in cumulus cells of mature MII oocytes from patients with polycystic ovary syndrome |
| Gene Symbol | Entrez ID | Uniprot ID | Score |
|---|---|---|---|
|
EEF1A1 |
1915 |
P68104 |
0.49 |
|
NR3C1 |
2908 |
P04150 |
0.49 |
|
IL7R |
3575 |
P16871 |
0.49 |
|
TPM2 |
7169 |
P07951 |
0.49 |
|
SMC3 |
9126 |
Q9UQE7 |
0.49 |
|
POLR1C |
9533 |
O15160 |
0.49 |
|
RBM34 |
23029 |
P42696 |
0.49 |
|
LARP7 |
51574 |
Q4G0J3 |
0.49 |
|
TRMT6 |
51605 |
Q9UJA5 |
0.49 |
|
WDR74 |
54663 |
Q6RFH5 |
0.49 |
|
NAT10 |
55226 |
Q9H0A0 |
0.49 |
|
ANKMY2 |
57037 |
Q8IV38 |
0.49 |
|
NIFK |
84365 |
Q9BYG3 |
0.49 |
|
SSB |
6741 |
P05455 |
0.55 |
|
APP |
351 |
P05067 |
0.56 |
|
POLE |
5426 |
Q07864 |
0.56 |
|
ZNF593 |
51042 |
O00488 |
0.56 |
|
CTTN |
2017 |
Q14247 |
0.63 |
|
KARS |
3735 |
Q15046 |
0.63 |
|
PPP2CA |
5515 |
P67775 |
0.63 |
|
CSNK2A1 |
1457 |
P68400 |
0.86 |
|
EWSR1 |
2130 |
Q01844 |
0.49 |
|
MYH9 |
4627 |
P35579 |
0.49 |
|
EXOSC10 |
5394 |
Q01780 |
0.49 |
|
RPL31 |
6160 |
P62899 |
0.49 |
|
RPS3 |
6188 |
P23396 |
0.49 |
|
RXRB |
6257 |
P28702 |
0.49 |
|
SNRPA1 |
6627 |
P09661 |
0.49 |
|
SNRPB2 |
6629 |
P08579 |
0.49 |
|
SAFB2 |
9667 |
Q14151 |
0.49 |
|
ABI1 |
10006 |
Q8IZP0 |
0.49 |
|
NOP56 |
10528 |
O00567 |
0.49 |
|
CDC37 |
11140 |
Q16543 |
0.49 |
|
SCHIP1 |
29970 |
Q9P0W5 |
0.49 |
|
PUS7 |
54517 |
Q96PZ0 |
0.49 |
|
DDX27 |
55661 |
Q96GQ7 |
0.49 |
|
DDX54 |
79039 |
Q8TDD1 |
0.49 |
|
CSNK2B |
1460 |
P67870 |
0.52 |
|
GZMH |
2999 |
P20718 |
0.52 |
|
XIAP |
331 |
P98170 |
0.63 |
|
BARD1 |
580 |
Q99728 |
0.63 |
|
BMI1 |
648 |
P35226 |
0.63 |
|
CDK2 |
1017 |
P24941 |
0.63 |
|
ELAVL1 |
1994 |
Q15717 |
0.63 |
|
EMD |
2010 |
P50402 |
0.63 |
|
ESR1 |
2099 |
P03372 |
0.63 |
|
H2AFX |
3014 |
P16104 |
0.63 |
|
HDGF |
3068 |
P51858 |
0.63 |
|
HNRNPA1 |
3178 |
P09651 |
0.63 |
|
HTR7 |
3363 |
P34969 |
0.63 |
|
JUN |
3725 |
P05412 |
0.63 |
|
MDM2 |
4193 |
Q00987 |
0.63 |
|
NEDD8 |
4738 |
Q15843 |
0.63 |
|
NME2 |
4831 |
P22392 |
0.63 |
|
YBX1 |
4904 |
P67809 |
0.63 |
|
NTRK1 |
4914 |
P04629 |
0.63 |
|
PRKAB1 |
5564 |
Q9Y478 |
0.63 |
|
RABGGTA |
5875 |
Q92696 |
0.63 |
|
RNF2 |
6045 |
Q99496 |
0.63 |
|
SUMO2 |
6613 |
P61956 |
0.63 |
|
SOX2 |
6657 |
P48431 |
0.63 |
|
SPIB |
6689 |
Q01892 |
0.63 |
|
SPP1 |
6696 |
P10451 |
0.63 |
|
TROVE2 |
6738 |
P10155 |
0.63 |
|
SURF2 |
6835 |
Q15527 |
0.63 |
|
TADA2A |
6871 |
O75478 |
0.63 |
|
TRAF6 |
7189 |
Q9Y4K3 |
0.63 |
|
VBP1 |
7411 |
P61758 |
0.63 |
|
VHL |
7428 |
P40337 |
0.63 |
|
ANP32A |
8125 |
P39687 |
0.63 |
|
CUL4B |
8450 |
Q13620 |
0.63 |
|
CUL3 |
8452 |
Q13618 |
0.63 |
|
CUL2 |
8453 |
Q13617 |
0.63 |
|
CUL1 |
8454 |
Q13616 |
0.63 |
|
TNFRSF14 |
8764 |
Q92956 |
0.63 |
|
IKBKE |
9641 |
Q14164 |
0.63 |
|
KIAA0101 |
9768 |
Q15004 |
0.63 |
|
UBA2 |
10054 |
Q9UBT2 |
0.63 |
|
DNM1L |
10059 |
O00429 |
0.63 |
|
HUWE1 |
10075 |
Q7Z6Z7 |
0.63 |
|
COPS5 |
10987 |
Q92905 |
0.63 |
|
GABARAP |
11337 |
O95166 |
0.63 |
|
GABARAPL2 |
11345 |
P60520 |
0.63 |
|
PAXIP1 |
22976 |
Q6ZW49 |
0.63 |
|
TARDBP |
23435 |
Q13148 |
0.63 |
|
SUZ12 |
23512 |
Q15022 |
0.63 |
|
GABARAPL1 |
23710 |
Q9H0R8 |
0.63 |
|
SIRT7 |
51547 |
Q9NRC8 |
0.63 |
|
LYAR |
55646 |
Q9NX58 |
0.63 |
|
NPLOC4 |
55666 |
Q8TAT6 |
0.63 |
|
CAND1 |
55832 |
Q86VP6 |
0.63 |
|
SMURF1 |
57154 |
Q9HCE7 |
0.63 |
|
LIN28A |
79727 |
Q9H9Z2 |
0.63 |
|
MAP1LC3B |
81631 |
Q9GZQ8 |
0.63 |
|
YWHAZ |
7534 |
P63104 |
0.68 |
|
CCNA2 |
890 |
P20248 |
0.72 |
|
FN1 |
2335 |
P02751 |
0.72 |
|
HMGA1 |
3159 |
P17096 |
0.72 |
|
IFIT3 |
3437 |
O14879 |
0.72 |
|
PRKCI |
5584 |
P41743 |
0.72 |
|
EIF2AK2 |
5610 |
P19525 |
0.72 |
|
SNCA |
6622 |
P37840 |
0.72 |
|
MAP3K14 |
9020 |
Q99558 |
0.72 |
|
ARFGEF1 |
10565 |
Q9Y6D6 |
0.72 |
|
TBC1D9 |
23158 |
Q6ZT07 |
0.72 |
|
CBX6 |
23466 |
O95503 |
0.72 |
|
TRIM33 |
51592 |
Q9UPN9 |
0.72 |
|
MRPL1 |
65008 |
Q9BYD6 |
0.72 |
|
ARMC6 |
93436 |
Q6NXE6 |
0.72 |
|
PMVK |
10654 |
Q15126 |
0.76 |
|
PUF60 |
22827 |
Q9UHX1 |
0.76 |
|
NCL |
4691 |
P19338 |
0.88 |