Protein Description

Gene Symbol SELL
Entrez ID 6402
Uniprot ID P14151
Description selectin L
Chromosomal Location chr1: 169,690,667-169,711,698
Ontology GO ID GO Term Definition Evidence

BP

GO:0007155

cell adhesion

The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules.

IEA

BP

GO:0033198

response to ATP

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ATP (adenosine 5'-triphosphate) stimulus.

IEA

BP

GO:0050776

regulation of immune response

Any process that modulates the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.

TAS

BP

GO:0050900

leukocyte migration

The movement of a leukocyte within or between different tissues and organs of the body.

TAS

CC

GO:0005886

plasma membrane

The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

TAS

CC

GO:0005887

integral component of plasma membrane

The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

TAS

CC

GO:0009897

external side of plasma membrane

The leaflet of the plasma membrane that faces away from the cytoplasm and any proteins embedded or anchored in it or attached to its surface.

IEA

MF

GO:0002020

protease binding

Interacting selectively and non-covalently with any protease or peptidase.

IPI

MF

GO:0005515

protein binding

Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).

IPI

MF

GO:0008201

heparin binding

Interacting selectively and non-covalently with heparin, any member of a group of glycosaminoglycans found mainly as an intracellular component of mast cells and which consist predominantly of alternating alpha-(1->4)-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues.

TAS

MF

GO:0030246

carbohydrate binding

Interacting selectively and non-covalently with any carbohydrate, which includes monosaccharides, oligosaccharides and polysaccharides as well as substances derived from monosaccharides by reduction of the carbonyl group (alditols), by oxidation of one or more hydroxy groups to afford the corresponding aldehydes, ketones, or carboxylic acids, or by replacement of one or more hydroxy group(s) by a hydrogen atom. Cyclitols are generally not regarded as carbohydrates.

IEA

MF

GO:0043208

glycosphingolipid binding

Interacting selectively and non-covalently with glycosphingolipid, a compound with residues of sphingoid and at least one monosaccharide.

TAS

MF

GO:0050839

cell adhesion molecule binding

Interacting selectively and non-covalently with a cell adhesion molecule.

IEA

Domain ID Description

IPR000436

Sushi/SCR/CCP domain

IPR000742

EGF-like domain

IPR001304

C-type lectin-like

IPR002396

Selectin superfamily

IPR013032

EGF-like, conserved site

IPR016186

C-type lectin-like/link domain

IPR016187

C-type lectin fold

IPR016348

L-selectin

IPR018378

C-type lectin, conserved site

IPR033991

Selectin, C-type lectin-like domain

Pathway ID Pathway Term Pathway Source

hsa04514

Cell adhesion molecules (CAMs)

KEGG

h_granulocytesPathway

Adhesion and Diapedesis of Granulocytes

BioCarta

h_lympathway

Adhesion and Diapedesis of Lymphocytes

BioCarta

h_lymphocytePathway

Adhesion Molecules on Lymphocyte

BioCarta

h_monocytePathway

Monocyte and its Surface Molecules

BioCarta

h_neutrophilPathway

Neutrophil and Its Surface Molecules

BioCarta

UMLS CUI UMLS Term

C0017661

Iga Glomerulonephritis

C0027051

Myocardial Infarction

Tissue Cell Type

appendix

lymphoid tissue

bone marrow

hematopoietic cells

lymph node

non-germinal center cells

spleen

cells in white pulp

tonsil

germinal center cells

tonsil

non-germinal center cells

No databases found.

Pubmed ID Author Year Title

25393639

Ambekar et al.

2014

Proteomics of follicular fluid from women with polycystic ovary syndrome suggests molecular defects in follicular development

Gene Symbol Entrez ID Uniprot ID Score

CD4

920

P01730

0.52

SELPLG

6404

Q14242

0.55

PRKCQ

5588

Q04759

0.56

GRB2

2885

P62993

0.73

PODXL

5420

O00592

0.73

SELE

6401

P16581

0.73

VCAN

1462

P13611

0.75

CFH

3075

P08603

0.75

MSN

4478

P26038

0.75

EZR

7430

P15311

0.75

PRKG1

5592

Q13976

0.52

PRKCA

5578

P17252

0.70

EMCN

51705

Q9ULC0

0.73

MUC7

4589

Q8TAX7

0.75

PODXL2

50512

Q9NZ53

0.75