Gene Symbol | BCS1L |
Entrez ID | 617 |
Uniprot ID | Q9Y276 |
Description | BCS1 homolog, ubiquinol-cytochrome c reductase complex chaperone |
Chromosomal Location | chr2: 218,658,764-218,663,443 |
Ontology | GO ID | GO Term | Definition | Evidence |
---|---|---|---|---|
BP |
GO:0007005 |
mitochondrion organization |
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a mitochondrion; includes mitochondrial morphogenesis and distribution, and replication of the mitochondrial genome as well as synthesis of new mitochondrial components. |
IMP |
BP |
GO:0032981 |
mitochondrial respiratory chain complex I assembly |
The aggregation, arrangement and bonding together of a set of components to form mitochondrial respiratory chain complex I. |
IMP |
BP |
GO:0033617 |
mitochondrial respiratory chain complex IV assembly |
The aggregation, arrangement and bonding together of a set of components to form respiratory chain complex IV (also known as cytochrome c oxidase) in the mitochondrial inner membrane. |
IMP |
BP |
GO:0034551 |
mitochondrial respiratory chain complex III assembly |
The aggregation, arrangement and bonding together of a set of components to form the cytochrome bc(1) complex (also known as ubiquinol-cytochrome c reductase), in the mitochondrial inner membrane. |
IMP |
CC |
GO:0005739 |
mitochondrion |
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration. |
IDA |
CC |
GO:0005750 |
mitochondrial respiratory chain complex III |
A protein complex located in the mitochondrial inner membrane that forms part of the mitochondrial respiratory chain. Contains about 10 polypeptide subunits including four redox centers: cytochrome b/b6, cytochrome c1 and an 2Fe-2S cluster. Catalyzes the oxidation of ubiquinol by oxidized cytochrome c1. |
TAS |
MF |
GO:0005515 |
protein binding |
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules). |
IPI |
MF |
GO:0005524 |
ATP binding |
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
IEA |
Domain ID | Description |
---|---|
IPR003593 |
AAA+ ATPase domain |
IPR003959 |
ATPase, AAA-type, core |
IPR003960 |
ATPase, AAA-type, conserved site |
IPR014851 |
BCS1, N-terminal |
IPR027243 |
Mitochondrial chaperone BCS1 |
IPR027417 |
P-loop containing nucleoside triphosphate hydrolase |
UMLS CUI | UMLS Term |
---|---|
C0023264 |
Leigh Disease |
Tissue | Cell Type |
---|---|
adrenal gland |
glandular cells |
appendix |
glandular cells |
colon |
glandular cells |
duodenum |
glandular cells |
esophagus |
squamous epithelial cells |
fallopian tube |
glandular cells |
gallbladder |
glandular cells |
liver |
hepatocytes |
lung |
macrophages |
ovary |
follicle cells |
pancreas |
islets of Langerhans |
placenta |
trophoblastic cells |
rectum |
glandular cells |
small intestine |
glandular cells |
stomach |
glandular cells |
testis |
Leydig cells |
Pubmed ID | Author | Year | Title |
---|---|---|---|
22789864 |
Yan et al. |
2012 |
Expression of apoptosis-related genes in the endometrium of polycystic ovary syndrome patients during the window of implantation |
Gene Symbol | Entrez ID | Uniprot ID | Score |
---|---|---|---|
UQCRFS1 |
7386 |
P47985 |
0.49 |
AIFM1 |
9131 |
O95831 |
0.49 |
VAPA |
9218 |
Q9P0L0 |
0.49 |
MRPL10 |
124995 |
Q7Z7H8 |
0.49 |
DNAJA1 |
3301 |
P31689 |
0.63 |
LETM1 |
3954 |
O95202 |
0.63 |
DDX24 |
57062 |
Q9GZR7 |
0.63 |
UCKL1 |
54963 |
Q9NWZ5 |
0.49 |
FUS |
2521 |
P35637 |
0.63 |
TMEFF1 |
8577 |
Q8IYR6 |
0.63 |
UBD |
10537 |
O15205 |
0.63 |
RBFOX2 |
23543 |
O43251 |
0.63 |
VPS26A |
9559 |
O75436 |
0.72 |