Protein Description

Gene Symbol S100P
Entrez ID 6286
Uniprot ID P25815
Description S100 calcium binding protein P
Chromosomal Location chr4: 6,693,069-6,697,170
Ontology GO ID GO Term Definition Evidence

BP

GO:0010033

response to organic substance

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic substance stimulus.

IEP

BP

GO:0043542

endothelial cell migration

The orderly movement of an endothelial cell into the extracellular matrix to form an endothelium.

IMP

BP

GO:0098609

cell-cell adhesion

The attachment of one cell to another cell via adhesion molecules.

IEA

CC

GO:0005634

nucleus

A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

IDA

CC

GO:0005737

cytoplasm

All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

IDA|TAS

CC

GO:0005913

cell-cell adherens junction

An adherens junction which connects a cell to another cell.

IDA

CC

GO:0031528

microvillus membrane

The portion of the plasma membrane surrounding a microvillus.

IEA

CC

GO:0070062

extracellular exosome

A membrane-bounded vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.

IDA

MF

GO:0000287

magnesium ion binding

Interacting selectively and non-covalently with magnesium (Mg) ions.

TAS

MF

GO:0005509

calcium ion binding

Interacting selectively and non-covalently with calcium ions (Ca2+).

IEA

MF

GO:0005515

protein binding

Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).

IPI

MF

GO:0048306

calcium-dependent protein binding

Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules), in the presence of calcium.

IPI

MF

GO:0050786

RAGE receptor binding

Interacting selectively and non-covalently with the RAGE receptor, the receptor for advanced glycation end-products.

IEA

MF

GO:0098641

cadherin binding involved in cell-cell adhesion

Any cadherin binding that occurs as part of the process of cell-cell adhesion.

IDA

Domain ID Description

IPR001751

S100/Calbindin-D9k, conserved site

IPR002048

EF-hand domain

IPR011992

EF-hand domain pair

IPR013787

S100/CaBP-9k-type, calcium binding, subdomain

IPR028494

Protein S100-P

IPR034325

S-100

Pathway ID Pathway Term Pathway Source

WP2361

Gastric Cancer Network 1

WikiPathways

No diseases found.

Tissue Cell Type

bone marrow

hematopoietic cells

placenta

trophoblastic cells

stomach

glandular cells

urinary bladder

urothelial cells

Database Name

DisGeNET

Pubmed ID Author Year Title

21411543

Savaris et al.

2011

Progesterone Resistance in PCOS Endometrium: A Microarray Analysis in Clomiphene Citrate-Treated and Artificial Menstrual Cycles

Gene Symbol Entrez ID Uniprot ID Score

MOK

5891

Q9UQ07

0.63

TFIP11

24144

Q9UBB9

0.63

S100A2

6273

P29034

0.65

S100A4

6275

P26447

0.65

AGER

177

Q15109

0.86

EZR

7430

P15311

0.88

S100P

6286

P25815

0.90

IGBP1

3476

P78318

0.49

PPM1G

5496

O15355

0.49

PSMD4

5710

P55036

0.49

SNRPF

6636

P62306

0.49

LRRC45

201255

Q96CN5

0.49

SUGT1

10910

Q9Y2Z0

0.62

CACYBP

27101

Q9HB71

0.62

BAG3

9531

O95817

0.63

NUSAP1

51203

Q9BXS6

0.63

STUB1

10273

Q9UNE7

0.65

MYH9

4627

P35579

0.72

TERF2IP

54386

Q9NYB0

0.75

S100Z

170591

Q8WXG8

0.78

S100B

6285

P04271

0.86

S100A1

6271

P23297

0.90