| Gene Symbol | S100A10 |
| Entrez ID | 6281 |
| Uniprot ID | P60903 |
| Description | S100 calcium binding protein A10 |
| Chromosomal Location | chr1: 151,982,915-151,994,390 |
| Ontology | GO ID | GO Term | Definition | Evidence |
|---|---|---|---|---|
|
BP |
GO:0001765 |
membrane raft assembly |
The aggregation, arrangement and bonding together of a set of components to form a membrane raft, a small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalizes cellular processes. |
IDA |
|
BP |
GO:0006900 |
membrane budding |
The evagination of a membrane, resulting in formation of a vesicle. |
IDA |
|
BP |
GO:0043547 |
positive regulation of GTPase activity |
Any process that activates or increases the activity of a GTPase. |
IMP |
|
BP |
GO:0051099 |
positive regulation of binding |
Any process that activates or increases the rate or extent of binding, the selective interaction of a molecule with one or more specific sites on another molecule. |
IEA |
|
BP |
GO:0051290 |
protein heterotetramerization |
The formation of a protein heterotetramer, a macromolecular structure consisting of four noncovalently associated subunits, of which not all are identical. |
IDA |
|
BP |
GO:0051496 |
positive regulation of stress fiber assembly |
Any process that activates or increases the frequency, rate or extent of the assembly of a stress fiber, a bundle of microfilaments and other proteins found in fibroblasts. |
IMP |
|
BP |
GO:0051894 |
positive regulation of focal adhesion assembly |
Any process that activates or increases the frequency, rate or extent of focal adhesion assembly, the establishment and maturation of focal adhesions. |
IMP |
|
BP |
GO:0090002 |
establishment of protein localization to plasma membrane |
The directed movement of a protein to a specific location in the plasma membrane. |
IDA |
|
BP |
GO:1900026 |
positive regulation of substrate adhesion-dependent cell spreading |
Any process that activates or increases the frequency, rate or extent of substrate adhesion-dependent cell spreading. |
IMP |
|
CC |
GO:0019897 |
extrinsic component of plasma membrane |
The component of a plasma membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region. |
IEA |
|
CC |
GO:0045121 |
membrane raft |
Any of the small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes. Small rafts can sometimes be stabilized to form larger platforms through protein-protein and protein-lipid interactions. |
IDA |
|
CC |
GO:0070062 |
extracellular exosome |
A membrane-bounded vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm. |
IDA |
|
MF |
GO:0005509 |
calcium ion binding |
Interacting selectively and non-covalently with calcium ions (Ca2+). |
IEA |
|
MF |
GO:0005515 |
protein binding |
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules). |
IPI |
|
MF |
GO:0042803 |
protein homodimerization activity |
Interacting selectively and non-covalently with an identical protein to form a homodimer. |
IDA |
|
MF |
GO:0044325 |
ion channel binding |
Interacting selectively and non-covalently with one or more specific sites on an ion channel, a protein complex that spans a membrane and forms a water-filled channel across the phospholipid bilayer allowing selective ion transport down its electrochemical gradient. |
IPI |
| Domain ID | Description |
|---|---|
|
IPR001751 |
S100/Calbindin-D9k, conserved site |
|
IPR011992 |
EF-hand domain pair |
|
IPR013787 |
S100/CaBP-9k-type, calcium binding, subdomain |
|
IPR028476 |
Protein S100-A10 |
| Pathway ID | Pathway Term | Pathway Source |
|---|---|---|
|
WP98 |
Prostaglandin Synthesis and Regulation |
WikiPathways |
| UMLS CUI | UMLS Term |
|---|---|
|
C0011581 |
Depressive Disorder |
|
C0022548 |
Keloid |
|
C0023467 |
Leukemia, Myelocytic, Acute |
|
C0025149 |
Medulloblastoma |
| Tissue | Cell Type |
|---|---|
|
adrenal gland |
glandular cells |
|
appendix |
glandular cells |
|
breast |
glandular cells |
|
bronchus |
respiratory epithelial cells |
|
cerebral cortex |
endothelial cells |
|
cervix, uterine |
squamous epithelial cells |
|
colon |
glandular cells |
|
duodenum |
glandular cells |
|
endometrium |
glandular cells |
|
esophagus |
squamous epithelial cells |
|
fallopian tube |
glandular cells |
|
gallbladder |
glandular cells |
|
kidney |
cells in glomeruli |
|
lung |
macrophages |
|
lung |
pneumocytes |
|
lymph node |
non-germinal center cells |
|
nasopharynx |
respiratory epithelial cells |
|
oral mucosa |
squamous epithelial cells |
|
ovary |
ovarian stroma cells |
|
pancreas |
exocrine glandular cells |
|
placenta |
trophoblastic cells |
|
prostate |
glandular cells |
|
rectum |
glandular cells |
|
seminal vesicle |
glandular cells |
|
skin |
fibroblasts |
|
skin |
keratinocytes |
|
skin |
melanocytes |
|
skin |
epidermal cells |
|
small intestine |
glandular cells |
|
soft tissue |
fibroblasts |
|
soft tissue |
peripheral nerve |
|
spleen |
cells in red pulp |
|
testis |
Leydig cells |
|
tonsil |
squamous epithelial cells |
|
vagina |
squamous epithelial cells |
| Pubmed ID | Author | Year | Title |
|---|---|---|---|
|
22951915 |
Haozi et al. |
2012 |
Altered gene expression profile in cumulus cells of mature MII oocytes from patients with polycystic ovary syndrome |
| Gene Symbol | Entrez ID | Uniprot ID | Score |
|---|---|---|---|
|
ATP6V1E1 |
529 |
P36543 |
0.49 |
|
HDLBP |
3069 |
Q00341 |
0.49 |
|
SIN3A |
25942 |
Q96ST3 |
0.49 |
|
ZFR |
51663 |
Q96KR1 |
0.49 |
|
UBAP2 |
55833 |
Q5T6F2 |
0.49 |
|
SRPRB |
58477 |
Q9Y5M8 |
0.49 |
|
WDR92 |
116143 |
Q96MX6 |
0.49 |
|
TMEM65 |
157378 |
Q6PI78 |
0.49 |
|
SRP9 |
653226 |
P49458 |
0.49 |
|
SUPT6H |
6830 |
Q7KZ85 |
0.63 |
|
SETDB1 |
9869 |
Q15047 |
0.63 |
|
DLC1 |
10395 |
Q96QB1 |
0.63 |
|
COPS6 |
10980 |
Q7L5N1 |
0.63 |
|
TRPV5 |
56302 |
Q9NQA5 |
0.77 |
|
S100A10 |
6281 |
P60903 |
0.90 |
|
CD55 |
1604 |
P08174 |
0.49 |
|
ELAVL1 |
1994 |
Q15717 |
0.49 |
|
RPL10A |
4736 |
P62906 |
0.49 |
|
RPL12 |
6136 |
P30050 |
0.49 |
|
PPIF |
10105 |
P30405 |
0.49 |
|
FLOT1 |
10211 |
O75955 |
0.49 |
|
ZMPSTE24 |
10269 |
O75844 |
0.49 |
|
FAF2 |
23197 |
Q96CS3 |
0.49 |
|
PHF5A |
84844 |
Q7RTV0 |
0.49 |
|
RPL10L |
140801 |
Q96L21 |
0.49 |
|
ANXA7 |
310 |
P20073 |
0.62 |
|
CD81 |
975 |
P60033 |
0.63 |
|
EEF1G |
1937 |
P26641 |
0.63 |
|
ERBB3 |
2065 |
P21860 |
0.63 |
|
FSHR |
2492 |
P23945 |
0.63 |
|
GDNF |
2668 |
P39905 |
0.63 |
|
NPM1 |
4869 |
P06748 |
0.63 |
|
CDK16 |
5127 |
Q00536 |
0.63 |
|
PDYN |
5173 |
P01213 |
0.63 |
|
PLA2G4A |
5321 |
P47712 |
0.63 |
|
ABCE1 |
6059 |
P61221 |
0.63 |
|
UQCRB |
7381 |
P14927 |
0.63 |
|
PLG |
5340 |
P00747 |
0.65 |
|
HLTF |
6596 |
Q14527 |
0.68 |
|
ATF2 |
1386 |
P15336 |
0.72 |
|
FLNA |
2316 |
P21333 |
0.72 |
|
PLA2G4C |
8605 |
Q9UP65 |
0.75 |
|
AHNAK |
79026 |
Q09666 |
0.76 |
|
KCNK3 |
3777 |
O14649 |
0.78 |
|
TRPV6 |
55503 |
Q9H1D0 |
0.85 |
|
BAD |
572 |
Q92934 |
0.87 |
|
CTSB |
1508 |
P07858 |
0.87 |
|
ANXA2 |
302 |
P07355 |
0.90 |