Protein Description

Gene Symbol RRAD
Entrez ID 6236
Uniprot ID P55042
Description Ras-related associated with diabetes
Chromosomal Location chr16: 66,921,679-66,925,644
Ontology GO ID GO Term Definition Evidence

BP

GO:0007264

small GTPase mediated signal transduction

Any series of molecular signals in which a small monomeric GTPase relays one or more of the signals.

IEA

CC

GO:0005622

intracellular

The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.

IEA

CC

GO:0005886

plasma membrane

The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

IEA

MF

GO:0003924

GTPase activity

Catalysis of the reaction: GTP + H2O = GDP + phosphate.

TAS

MF

GO:0005515

protein binding

Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).

IPI

MF

GO:0005516

calmodulin binding

Interacting selectively and non-covalently with calmodulin, a calcium-binding protein with many roles, both in the calcium-bound and calcium-free states.

IEA

MF

GO:0005525

GTP binding

Interacting selectively and non-covalently with GTP, guanosine triphosphate.

IEA

Domain ID Description

IPR001806

Small GTPase superfamily

IPR005225

Small GTP-binding protein domain

IPR017358

Small GTPase superfamily, GEM/REM/Rad

IPR020849

Small GTPase superfamily, Ras type

IPR027417

P-loop containing nucleoside triphosphate hydrolase

IPR028869

GTP-binding protein Rad

Pathway ID Pathway Term Pathway Source

WP481

Insulin Signaling

WikiPathways

UMLS CUI UMLS Term

C0007131

Non-Small Cell Lung Carcinoma

C0018800

Cardiomegaly

C1458155

Mammary Neoplasms

Tissue Cell Type

bronchus

respiratory epithelial cells

cerebral cortex

neuropil

fallopian tube

glandular cells

nasopharynx

respiratory epithelial cells

oral mucosa

squamous epithelial cells

placenta

decidual cells

No databases found.

Pubmed ID Author Year Title

22617121

Ouandaogo et al.

2012

Differences in transcriptomic profiles of human cumulus cells isolated from oocytes at GV, MI and MII stages after in vivo andin vitro oocyte maturation

Gene Symbol Entrez ID Uniprot ID Score

CCDC141

285025

Q6ZP82

0.63

CALM2

805

P62158

0.71

CALM3

808

P62158

0.71

CCNDBP1

23582

O95273

0.75

NME1

4830

P15531

0.84

CSNK2B

1460

P67870

0.52

PRKCB

5579

P05771

0.62

MMP14

4323

P50281

0.63

CSNK2A1

1457

P68400

0.65

PRKACA

5566

P17612

0.65

PRKCA

5578

P17252

0.65

TPM2

7169

P07951

0.79

YWHAZ

7534

P63104

0.80

CAMK2G

818

Q13555

0.89