Gene Symbol | RRAD |
Entrez ID | 6236 |
Uniprot ID | P55042 |
Description | Ras-related associated with diabetes |
Chromosomal Location | chr16: 66,921,679-66,925,644 |
Ontology | GO ID | GO Term | Definition | Evidence |
---|---|---|---|---|
BP |
GO:0007264 |
small GTPase mediated signal transduction |
Any series of molecular signals in which a small monomeric GTPase relays one or more of the signals. |
IEA |
CC |
GO:0005622 |
intracellular |
The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm. |
IEA |
CC |
GO:0005886 |
plasma membrane |
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
IEA |
MF |
GO:0003924 |
GTPase activity |
Catalysis of the reaction: GTP + H2O = GDP + phosphate. |
TAS |
MF |
GO:0005515 |
protein binding |
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules). |
IPI |
MF |
GO:0005516 |
calmodulin binding |
Interacting selectively and non-covalently with calmodulin, a calcium-binding protein with many roles, both in the calcium-bound and calcium-free states. |
IEA |
MF |
GO:0005525 |
GTP binding |
Interacting selectively and non-covalently with GTP, guanosine triphosphate. |
IEA |
Domain ID | Description |
---|---|
IPR001806 |
Small GTPase superfamily |
IPR005225 |
Small GTP-binding protein domain |
IPR017358 |
Small GTPase superfamily, GEM/REM/Rad |
IPR020849 |
Small GTPase superfamily, Ras type |
IPR027417 |
P-loop containing nucleoside triphosphate hydrolase |
IPR028869 |
GTP-binding protein Rad |
Pathway ID | Pathway Term | Pathway Source |
---|---|---|
WP481 |
Insulin Signaling |
WikiPathways |
UMLS CUI | UMLS Term |
---|---|
C0007131 |
Non-Small Cell Lung Carcinoma |
C0018800 |
Cardiomegaly |
C1458155 |
Mammary Neoplasms |
Tissue | Cell Type |
---|---|
bronchus |
respiratory epithelial cells |
cerebral cortex |
neuropil |
fallopian tube |
glandular cells |
nasopharynx |
respiratory epithelial cells |
oral mucosa |
squamous epithelial cells |
placenta |
decidual cells |
Pubmed ID | Author | Year | Title |
---|---|---|---|
22617121 |
Ouandaogo et al. |
2012 |
Differences in transcriptomic profiles of human cumulus cells isolated from oocytes at GV, MI and MII stages after in vivo andin vitro oocyte maturation |
Gene Symbol | Entrez ID | Uniprot ID | Score |
---|---|---|---|
CCDC141 |
285025 |
Q6ZP82 |
0.63 |
CALM2 |
805 |
P62158 |
0.71 |
CALM3 |
808 |
P62158 |
0.71 |
CCNDBP1 |
23582 |
O95273 |
0.75 |
NME1 |
4830 |
P15531 |
0.84 |
CSNK2B |
1460 |
P67870 |
0.52 |
PRKCB |
5579 |
P05771 |
0.62 |
MMP14 |
4323 |
P50281 |
0.63 |
CSNK2A1 |
1457 |
P68400 |
0.65 |
PRKACA |
5566 |
P17612 |
0.65 |
PRKCA |
5578 |
P17252 |
0.65 |
TPM2 |
7169 |
P07951 |
0.79 |
YWHAZ |
7534 |
P63104 |
0.80 |
CAMK2G |
818 |
Q13555 |
0.89 |