Gene Symbol | MRPS12 |
Entrez ID | 6183 |
Uniprot ID | O15235 |
Description | mitochondrial ribosomal protein S12 |
Chromosomal Location | chr19: 38,930,548-38,933,162 |
Ontology | GO ID | GO Term | Definition | Evidence |
---|---|---|---|---|
BP |
GO:0006412 |
translation |
The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA. Translation ends with the release of a polypeptide chain from the ribosome. |
IBA |
BP |
GO:0032543 |
mitochondrial translation |
The chemical reactions and pathways resulting in the formation of a protein in a mitochondrion. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein; the mitochondrion has its own ribosomes and transfer RNAs, and uses a genetic code that differs from the nuclear code. |
ISS |
BP |
GO:0070125 |
mitochondrial translational elongation |
The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis in a mitochondrion. |
TAS |
BP |
GO:0070126 |
mitochondrial translational termination |
The process resulting in the release of a polypeptide chain from the ribosome in a mitochondrion, usually in response to a termination codon (note that mitochondria use variants of the universal genetic code that differ between different taxa). |
TAS |
CC |
GO:0005743 |
mitochondrial inner membrane |
The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae. |
TAS |
CC |
GO:0005761 |
mitochondrial ribosome |
A ribosome found in the mitochondrion of a eukaryotic cell; contains a characteristic set of proteins distinct from those of cytosolic ribosomes. |
TAS |
CC |
GO:0005763 |
mitochondrial small ribosomal subunit |
The smaller of the two subunits of a mitochondrial ribosome. |
ISS |
MF |
GO:0003735 |
structural constituent of ribosome |
The action of a molecule that contributes to the structural integrity of the ribosome. |
ISS |
MF |
GO:0044822 |
poly(A) RNA binding |
Interacting non-covalently with a poly(A) RNA, a RNA molecule which has a tail of adenine bases. |
IDA |
Domain ID | Description |
---|---|
IPR005679 |
Ribosomal protein S12, bacterial-type |
IPR006032 |
Ribosomal protein S12/S23 |
IPR012340 |
Nucleic acid-binding, OB-fold |
Pathway ID | Pathway Term | Pathway Source |
---|---|---|
hsa03010 |
Ribosome |
KEGG |
Tissue | Cell Type |
---|---|
adrenal gland |
glandular cells |
appendix |
glandular cells |
breast |
glandular cells |
breast |
myoepithelial cells |
bronchus |
respiratory epithelial cells |
cerebellum |
cells in granular layer |
colon |
glandular cells |
duodenum |
glandular cells |
endometrium |
glandular cells |
esophagus |
squamous epithelial cells |
fallopian tube |
glandular cells |
gallbladder |
glandular cells |
heart muscle |
myocytes |
hippocampus |
neuronal cells |
kidney |
cells in tubules |
liver |
hepatocytes |
nasopharynx |
respiratory epithelial cells |
parathyroid gland |
glandular cells |
placenta |
decidual cells |
rectum |
glandular cells |
salivary gland |
glandular cells |
seminal vesicle |
glandular cells |
small intestine |
glandular cells |
soft tissue |
fibroblasts |
stomach |
glandular cells |
testis |
cells in seminiferous ducts |
testis |
Leydig cells |
thyroid gland |
glandular cells |
vagina |
squamous epithelial cells |
Pubmed ID | Author | Year | Title |
---|---|---|---|
19141487 |
Kenigsberg et al. |
2009 |
Gene expression microarray profiles of cumulus cells in lean and overweightobese polycystic ovary syndrome patients |
22617121 |
Ouandaogo et al. |
2012 |
Differences in transcriptomic profiles of human cumulus cells isolated from oocytes at GV, MI and MII stages after in vivo andin vitro oocyte maturation |
22951915 |
Haozi et al. |
2012 |
Altered gene expression profile in cumulus cells of mature MII oocytes from patients with polycystic ovary syndrome |
Gene Symbol | Entrez ID | Uniprot ID | Score |
---|---|---|---|
UNC119 |
9094 |
Q13432 |
0.63 |
C14orf1 |
11161 |
Q9UKR5 |
0.63 |
RIF1 |
55183 |
Q5UIP0 |
0.63 |
LRIF1 |
55791 |
Q5T3J3 |
0.63 |
RPS3 |
6188 |
P23396 |
0.56 |
CRMP1 |
1400 |
Q14194 |
0.63 |
RIOK2 |
55781 |
Q9BVS4 |
0.63 |
CNOT2 |
4848 |
Q9NZN8 |
0.72 |
CKAP5 |
9793 |
Q14008 |
0.72 |
MPHOSPH8 |
54737 |
Q99549 |
0.72 |
ZSCAN5A |
79149 |
Q9BUG6 |
0.72 |
USP43 |
124739 |
Q70EL4 |
0.72 |
SPINK7 |
84651 |
P58062 |
0.73 |