PCOSBase

Protein Description

Gene Symbol	RPL31
Entrez ID	6160
Uniprot ID	P62899
Description	ribosomal protein L31
Chromosomal Location	chr2: 101,001,715-101,024,032

Download CSV

Ontology	GO ID	GO Term	Definition	Evidence
BP	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	The nonsense-mediated decay pathway for nuclear-transcribed mRNAs degrades mRNAs in which an amino-acid codon has changed to a nonsense codon; this prevents the translation of such mRNAs into truncated, and potentially harmful, proteins.	TAS
BP	GO:0002181	cytoplasmic translation	The chemical reactions and pathways resulting in the formation of a protein in the cytoplasm. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein.	IBA
BP	GO:0006364	rRNA processing	Any process involved in the conversion of a primary ribosomal RNA (rRNA) transcript into one or more mature rRNA molecules.	TAS
BP	GO:0006412	translation	The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA. Translation ends with the release of a polypeptide chain from the ribosome.	NAS
BP	GO:0006413	translational initiation	The process preceding formation of the peptide bond between the first two amino acids of a protein. This includes the formation of a complex of the ribosome, mRNA, and an initiation complex that contains the first aminoacyl-tRNA.	TAS
BP	GO:0006614	SRP-dependent cotranslational protein targeting to membrane	The targeting of proteins to a membrane that occurs during translation and is dependent upon two key components, the signal-recognition particle (SRP) and the SRP receptor. SRP is a cytosolic particle that transiently binds to the endoplasmic reticulum (ER) signal sequence in a nascent protein, to the large ribosomal unit, and to the SRP receptor in the ER membrane.	TAS
BP	GO:0019083	viral transcription	The process by which a viral genome, or part of a viral genome, is transcribed within the host cell.	TAS
CC	GO:0005829	cytosol	The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.	TAS
CC	GO:0005925	focal adhesion	Small region on the surface of a cell that anchors the cell to the extracellular matrix and that forms a point of termination of actin filaments.	IDA
CC	GO:0016020	membrane	A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.	IDA
CC	GO:0022625	cytosolic large ribosomal subunit	The large subunit of a ribosome located in the cytosol.	IDA
CC	GO:0070062	extracellular exosome	A membrane-bounded vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.	IDA
MF	GO:0003723	RNA binding	Interacting selectively and non-covalently with an RNA molecule or a portion thereof.	TAS
MF	GO:0003735	structural constituent of ribosome	The action of a molecule that contributes to the structural integrity of the ribosome.	NAS
MF	GO:0005515	protein binding	Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).	IPI
MF	GO:0044822	poly(A) RNA binding	Interacting non-covalently with a poly(A) RNA, a RNA molecule which has a tail of adenine bases.	IDA

Download CSV

Domain ID	Description
IPR000054	Ribosomal protein L31e
IPR020052	Ribosomal protein L31e, conserved site
IPR023621	Ribosomal protein L31e domain

Download CSV

Pathway ID	Pathway Term	Pathway Source
hsa03010	Ribosome	KEGG
WP477	Cytoplasmic Ribosomal Proteins	WikiPathways

Download CSV

UMLS CUI	UMLS Term
C1458155	Mammary Neoplasms

Download CSV

Tissue	Cell Type
appendix	glandular cells
breast	glandular cells
caudate	neuronal cells
cerebellum	cells in molecular layer
cerebellum	Purkinje cells
cerebral cortex	neuronal cells
cervix, uterine	squamous epithelial cells
colon	glandular cells
duodenum	glandular cells
endometrium	cells in endometrial stroma
endometrium	glandular cells
esophagus	squamous epithelial cells
fallopian tube	glandular cells
gallbladder	glandular cells
hippocampus	neuronal cells
pancreas	exocrine glandular cells
placenta	trophoblastic cells
rectum	glandular cells
seminal vesicle	glandular cells
skin	keratinocytes
skin	epidermal cells
small intestine	glandular cells
spleen	cells in white pulp
stomach	glandular cells
testis	cells in seminiferous ducts
thyroid gland	glandular cells
tonsil	germinal center cells
tonsil	squamous epithelial cells

No databases found.

Download CSV

Pubmed ID	Author	Year	Title
15291743	Diao et al.	2004	The molecular characteristics of polycystic ovary syndrome (PCOS) ovary defined by human ovary cDNA microarray

Download CSV

Gene Symbol	Entrez ID	Uniprot ID	Score
IL7R	3575	P16871	0.49
RPL3	6122	P39023	0.49
RPL13	6137	P26373	0.49
RPL27A	6157	P46776	0.49
RPL34	6164	P49207	0.49
RPL38	6169	P63173	0.49
RPLP1	6176	P05386	0.49
RPS9	6203	P46781	0.49
RPS17	6218	P08708	0.49
RPS25	6230	P62851	0.49
RPS27	6232	P42677	0.49
RPS27A	6233	P62979	0.49
SSB	6741	P05455	0.49
PES1	23481	O00541	0.49
RPL13A	23521	P40429	0.49
RPL36	25873	Q9Y3U8	0.49
RPS27L	51065	Q71UM5	0.49
DDX27	55661	Q96GQ7	0.49
RPLP0P6	220717	Q8NHW5	0.49
RPS21	100291837	P63220	0.49
RPL35A	6165	P18077	0.56
RPS24	6229	P62847	0.56
RPSA	3921	P08865	0.59
RPL4	6124	P36578	0.59
RPL5	6125	P46777	0.59
RPL6	6128	Q02878	0.59
RPL7	6129	P18124	0.59
RPL7A	6130	P62424	0.59
RPL8	6132	P62917	0.59
RPL37A	6168	P61513	0.59
RPLP0	6175	P05388	0.59
RPS2	6187	P15880	0.59
RPS3	6188	P23396	0.59
RPS3A	6189	P61247	0.59
RPS4X	6191	P62701	0.59
RPS5	6193	P46782	0.59
RPS6	6194	P62753	0.59
RPS7	6201	P62081	0.59
RPS8	6202	P62241	0.59
RPS10	6204	P46783	0.59
RPS11	6205	P62280	0.59
RPS12	6206	P25398	0.59
RPS13	6207	P62277	0.59
RPS14	6208	P62263	0.59
RPS15A	6210	P62244	0.59
RPS16	6217	P62249	0.59
RPS23	6228	P62266	0.59
RPS26	6231	P62854	0.59
RPL35	11224	P42766	0.59
RPL9; RPL9P7; RPL9P8; RPL9P9	6133	P32969	0.59
ALB	213	P02768	0.63
COL6A2	1292	P12110	0.63
CRKL	1399	P46109	0.63
DSP	1832	P15924	0.63
FLNB	2317	O75369	0.63
FLNC	2318	Q14315	0.63
FUS	2521	P35637	0.63
GATM	2628	P50440	0.63
GPR20	2843	Q99678	0.63
HSPA5	3309	P11021	0.63
TNC	3371	P24821	0.63
KPNB1	3837	Q14974	0.63
MDM2	4193	Q00987	0.63
MKI67	4288	P46013	0.63
NASP	4678	P49321	0.63
RPL31	6160	P62899	0.63
TKT	7086	P29401	0.63
VIM	7431	P08670	0.63
CDK5R2	8941	Q13319	0.63
KLF4	9314	O43474	0.63
TTC37	9652	Q6PGP7	0.63
CTCF	10664	P49711	0.63
KIAA0907	22889	Q7Z7F0	0.63
SRRM2	23524	Q9UQ35	0.63
TERF2IP	54386	Q9NYB0	0.63
TMEM57	55219	Q8N5G2	0.63
CCDC88A	55704	Q3V6T2	0.63
KIAA1217	56243	Q5T5P2	0.63
CPXM1	56265	Q96SM3	0.63
DDRGK1	65992	Q96HY6	0.63
RPS19	6223	P39019	0.65
APP	351	P05067	0.66
SLC25A5	292	P05141	0.49
DHX9	1660	Q08211	0.49
DHX15	1665	O43143	0.49
EEF1A1	1915	P68104	0.49
EEF2	1938	P13639	0.49
ILF2	3608	Q12905	0.49
ILF3	3609	Q12906	0.49
MOV10	4343	Q9HCE1	0.49
HNRNPM	4670	P52272	0.49
NAP1L1	4673	P55209	0.49
SNU13	4809	P55769	0.49
RPL17	6139	P18621	0.49
RPLP2	6181	P05387	0.49
RPS15	6209	P62841	0.49
RPS20	6224	P60866	0.49
SRP68	6730	Q9UHB9	0.49
TUFM	7284	P49411	0.49
MOGS	7841	Q13724	0.49
EIF4A3	9775	P38919	0.49
HNRNPR	10236	O43390	0.49
EBNA1BP2	10969	Q99848	0.49
RBMX	27316	P38159	0.49
MRTO4	51154	Q9UKD2	0.49
FTSJ3	117246	Q8IY81	0.49
RPL10L	140801	Q96L21	0.49
GRB2	2885	P62993	0.56
PTEN	5728	P60484	0.56
RPS18	6222	P62269	0.56
RPL10A	4736	P62906	0.59
RPL11	6135	P62913	0.59
RPL12	6136	P30050	0.59
RPL15	6138	P61313	0.59
RPL18	6141	Q07020	0.59
RPL19	6143	P84098	0.59
RPL21	6144	P46778	0.59
RPL22	6146	P35268	0.59
RPL23A	6147	P62750	0.59
RPL24	6152	P83731	0.59
RPL27	6155	P61353	0.59
RPL30	6156	P62888	0.59
RPL14	9045	P50914	0.59
RPL23	9349	P62829	0.59
NIFK	84365	Q9BYG3	0.59
ADRBK1	156	P25098	0.63
RHOC	389	P08134	0.63
BLVRB	645	P30043	0.63
LDLRAD4	753	O15165	0.63
CACNA1A	773	O00555	0.63
CALD1	800	Q05682	0.63
CD81	975	P60033	0.63
CDC5L	988	Q99459	0.63
CDK4	1019	P11802	0.63
CENPF	1063	P49454	0.63
CHD1	1105	O14646	0.63
CLDN3	1365	O15551	0.63
CR1	1378	P17927	0.63
CS	1431	O75390	0.63
MAPK14	1432	Q16539	0.63
CSK	1445	P41240	0.63
CSNK1A1	1452	P48729	0.63
CSNK1E	1454	P49674	0.63
CSNK2A2	1459	P19784	0.63
EIF1AX	1964	P47813	0.63
EIF4B	1975	P23588	0.63
ESR1	2099	P03372	0.63
FASN	2194	P49327	0.63
FDPS	2224	P14324	0.63
GSK3B	2932	P49841	0.63
MSH6	2956	P52701	0.63
HLA-E	3133	P13747	0.63
ICAM1	3383	P05362	0.63
ILK	3611	Q13418	0.63
JUN	3725	P05412	0.63
IPO5	3843	O00410	0.63
LAMB1	3912	P07942	0.63
MCM2	4171	P49736	0.63
MMP1	4312	P03956	0.63
MMP8	4317	P22894	0.63
MUC4	4585	Q99102	0.63
NACA	4666	Q13765	0.63
NOS2	4843	P35228	0.63
NOTCH1	4851	P46531	0.63
OAZ1	4946	P54368	0.63
P4HA1	5033	P13674	0.63
PAK1	5058	Q13153	0.63
PFN1	5216	P07737	0.63
PHKG2	5261	P15735	0.63
POU5F1	5460	Q01860	0.63
PRKAA1	5562	Q13131	0.63
PRKACA	5566	P17612	0.63
EIF2AK2	5610	P19525	0.63
PTPN13	5783	Q12923	0.63
RCN1	5954	Q15293	0.63
RNF2	6045	Q99496	0.63
RPS6KA1	6195	Q15418	0.63
STK3	6788	Q13188	0.63
TCF3	6929	P15923	0.63
TP53	7157	P04637	0.63
TPT1	7178	P13693	0.63
TTC3	7267	P53804	0.63
TUBG1	7283	P23258	0.63
VCAM1	7412	P19320	0.63
CUL5	8065	Q93034	0.63
USP11	8237	P51784	0.63
UBL4A	8266	P11441	0.63
FZD1	8321	Q9UP38	0.63
HIST1H3A	8350	P68431	0.63
STK24	8428	Q9Y6E0	0.63
CUL4B	8450	Q13620	0.63
CUL3	8452	Q13618	0.63
CUL2	8453	Q13617	0.63
CUL1	8454	Q13616	0.63
CAMK1	8536	Q14012	0.63
APOL1	8542	O14791	0.63
EED	8726	O75530	0.63
ITM2B	9445	Q9Y287	0.63
NFE2L3	9603	Q9Y4A8	0.63
IKBKE	9641	Q14164	0.63
KIAA0101	9768	Q15004	0.63
PAN2	9924	Q504Q3	0.63
OXSR1	9943	O95747	0.63
PPP4R1	9989	Q8TF05	0.63
EIF1B	10289	O60739	0.63
TUBGCP3	10426	Q96CW5	0.63
BAIAP2	10458	Q9UQB8	0.63
STK25	10494	O00506	0.63
CHERP	10523	Q8IWX8	0.63
AHSA1	10598	O95433	0.63
COPS6	10980	Q7L5N1	0.63
COPS5	10987	Q92905	0.63
CEP250	11190	Q9BV73	0.63
SEC23IP	11196	Q9Y6Y8	0.63
GABARAP	11337	O95166	0.63
GABARAPL2	11345	P60520	0.63
SNW1	22938	Q13573	0.63
UNC13A	23025	Q9UPW8	0.63
XPO6	23214	Q96QU8	0.63
ADGRL2	23266	O95490	0.63
FNBP4	23360	Q8N3X1	0.63
TARDBP	23435	Q13148	0.63
GABARAPL1	23710	Q9H0R8	0.63
AGO1	26523	Q9UL18	0.63
AGO2	27161	Q9UKV8	0.63
EEF2K	29904	O00418	0.63
CRIM1	51232	Q9NZV1	0.63
PCF11	51585	O94913	0.63
STK26	51765	Q9P289	0.63
CCSER2	54462	Q9H7U1	0.63
TRIM44	54765	Q96DX7	0.63
TMEM39A	55254	Q9NV64	0.63
WDR33	55339	Q9C0J8	0.63
RIOK2	55781	Q9BVS4	0.63
CAND1	55832	Q86VP6	0.63
PARD3	56288	Q8TEW0	0.63
XAB2	56949	Q9HCS7	0.63
SMURF1	57154	Q9HCE7	0.63
ZXDC	79364	Q2QGD7	0.63
CEP76	79959	Q8TAP6	0.63
MED25	81857	Q71SY5	0.63
MAP1LC3A	84557	Q9H492	0.63
MUM1	84939	Q2TAK8	0.63
GADD45GIP1	90480	Q8TAE8	0.63
IGSF8	93185	Q969P0	0.63
TP53RK	112858	Q96S44	0.63
CSMD2	114784	Q7Z408	0.63
HNRNPA1L2	144983	Q32P51	0.63
SPRED2	200734	Q7Z698	0.63
MED19	219541	A0JLT2	0.63
IYD	389434	Q6PHW0	0.63
EIF6	3692	P56537	0.65
RPL18A	6142	Q02543	0.65
ARRB2	409	P32121	0.72
FN1	2335	P02751	0.72
IFIT2	3433	P09913	0.72
TCEAL9	51186	Q9UHQ7	0.72
CDK2	1017	P24941	0.73
SUMO2	6613	P61956	0.73
DDX21	9188	Q9NR30	0.73
NOP56	10528	O00567	0.73
MAGEB2	4113	O15479	0.76
YWHAZ	7534	P63104	0.76
CNBP	7555	P62633	0.76
PSTPIP1	9051	O43586	0.76
PINX1	54984	Q96BK5	0.76
ASF1B	55723	Q9NVP2	0.76
BRCA1	672	P38398	0.77
NEDD8	4738	Q15843	0.82
PRKAB1	5564	Q9Y478	0.82
EWSR1	2130	Q01844	0.83
RPL10	6134	P27635	0.83
DDX56	54606	Q9NY93	0.83
LYAR	55646	Q9NX58	0.86