Protein Description

Gene Symbol RPL13
Entrez ID 6137
Uniprot ID P26373
Description ribosomal protein L13
Chromosomal Location chr16: 89,560,657-89,566,828
Ontology GO ID GO Term Definition Evidence

BP

GO:0000184

nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

The nonsense-mediated decay pathway for nuclear-transcribed mRNAs degrades mRNAs in which an amino-acid codon has changed to a nonsense codon; this prevents the translation of such mRNAs into truncated, and potentially harmful, proteins.

TAS

BP

GO:0006364

rRNA processing

Any process involved in the conversion of a primary ribosomal RNA (rRNA) transcript into one or more mature rRNA molecules.

TAS

BP

GO:0006412

translation

The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA. Translation ends with the release of a polypeptide chain from the ribosome.

NAS

BP

GO:0006413

translational initiation

The process preceding formation of the peptide bond between the first two amino acids of a protein. This includes the formation of a complex of the ribosome, mRNA, and an initiation complex that contains the first aminoacyl-tRNA.

TAS

BP

GO:0006614

SRP-dependent cotranslational protein targeting to membrane

The targeting of proteins to a membrane that occurs during translation and is dependent upon two key components, the signal-recognition particle (SRP) and the SRP receptor. SRP is a cytosolic particle that transiently binds to the endoplasmic reticulum (ER) signal sequence in a nascent protein, to the large ribosomal unit, and to the SRP receptor in the ER membrane.

TAS

BP

GO:0019083

viral transcription

The process by which a viral genome, or part of a viral genome, is transcribed within the host cell.

TAS

CC

GO:0005634

nucleus

A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

IDA

CC

GO:0005829

cytosol

The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

TAS

CC

GO:0016020

membrane

A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.

IDA

CC

GO:0022625

cytosolic large ribosomal subunit

The large subunit of a ribosome located in the cytosol.

IDA

CC

GO:0022626

cytosolic ribosome

A ribosome located in the cytosol.

TAS

MF

GO:0003723

RNA binding

Interacting selectively and non-covalently with an RNA molecule or a portion thereof.

TAS

MF

GO:0003735

structural constituent of ribosome

The action of a molecule that contributes to the structural integrity of the ribosome.

NAS

MF

GO:0005515

protein binding

Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).

IPI

MF

GO:0044822

poly(A) RNA binding

Interacting non-covalently with a poly(A) RNA, a RNA molecule which has a tail of adenine bases.

IDA

Domain ID Description

IPR001380

Ribosomal protein L13e

IPR018256

Ribosomal protein L13e, conserved site

IPR034295

Ribosomal protein L13, eukaryotic

Pathway ID Pathway Term Pathway Source

hsa03010

Ribosome

KEGG

WP477

Cytoplasmic Ribosomal Proteins

WikiPathways

UMLS CUI UMLS Term

C0038356

Stomach Neoplasms

C0242656

Disease Progression

Tissue Cell Type

appendix

glandular cells

cerebellum

Purkinje cells

duodenum

glandular cells

esophagus

squamous epithelial cells

fallopian tube

glandular cells

gallbladder

glandular cells

hippocampus

neuronal cells

kidney

cells in tubules

nasopharynx

respiratory epithelial cells

oral mucosa

squamous epithelial cells

pancreas

exocrine glandular cells

placenta

decidual cells

rectum

glandular cells

skin

epidermal cells

small intestine

glandular cells

stomach

glandular cells

tonsil

squamous epithelial cells

urinary bladder

urothelial cells

vagina

squamous epithelial cells

No databases found.

Pubmed ID Author Year Title

22951915

Haozi et al.

2012

Altered gene expression profile in cumulus cells of mature MII oocytes from patients with polycystic ovary syndrome

Gene Symbol Entrez ID Uniprot ID Score

RPSA

3921

P08865

0.49

RPL17

6139

P18621

0.49

RPL27

6155

P61353

0.49

RPL28

6158

P46779

0.49

RPL34

6164

P49207

0.49

RPL35A

6165

P18077

0.49

RPLP1

6176

P05386

0.49

RPS5

6193

P46782

0.49

RPS14

6208

P62263

0.49

RPS15

6209

P62841

0.49

RPS18

6222

P62269

0.49

RPS26

6231

P62854

0.49

RPS27

6232

P42677

0.49

RPS28

6234

P62857

0.49

RPL13A

23521

P40429

0.49

RPS27L

51065

Q71UM5

0.49

RPLP0P6

220717

Q8NHW5

0.49

RPS21

100291837

P63220

0.49

RPL9; RPL9P7; RPL9P8; RPL9P9

6133

P32969

0.49

FAU

2197

P62861

0.59

RPL4

6124

P36578

0.59

RPL5

6125

P46777

0.59

RPL6

6128

Q02878

0.59

RPL7

6129

P18124

0.59

RPL22

6146

P35268

0.59

RPL30

6156

P62888

0.59

RPL27A

6157

P46776

0.59

RPL37A

6168

P61513

0.59

RPS2

6187

P15880

0.59

RPS3

6188

P23396

0.59

RPS3A

6189

P61247

0.59

RPS4X

6191

P62701

0.59

RPS6

6194

P62753

0.59

RPS7

6201

P62081

0.59

RPS8

6202

P62241

0.59

RPS13

6207

P62277

0.59

RPS15A

6210

P62244

0.59

RPS16

6217

P62249

0.59

RPS20

6224

P60866

0.59

RPS23

6228

P62266

0.59

RPS25

6230

P62851

0.59

RPL14

9045

P50914

0.59

RPL23

9349

P62829

0.59

BRCA1

672

P38398

0.63

DARS

1615

P14868

0.63

GRB2

2885

P62993

0.63

GTF3C1

2975

Q12789

0.63

GTF3C2

2976

Q8WUA4

0.63

ICT1

3396

Q14197

0.63

MARS

4141

P56192

0.63

NCK1

4690

P16333

0.63

PIK3R1

5295

P27986

0.63

PLCG1

5335

P19174

0.63

QARS

5859

P47897

0.63

TRO

7216

Q12816

0.63

AIMP1

9255

Q12904

0.63

GTF3C3

9330

Q9Y5Q9

0.63

VPRBP

9730

Q9Y4B6

0.63

MRPL28

10573

Q13084

0.63

MRPS30

10884

Q9NP92

0.63

RBM34

23029

P42696

0.63

MRPS27

23107

Q92552

0.63

SENP3

26168

Q9H4L4

0.63

RANBP6

26953

O60518

0.63

PELP1

27043

Q8IZL8

0.63

MRPL42

28977

Q9Y6G3

0.63

MRPL13

28998

Q9BYD1

0.63

MRPL18

29074

Q9H0U6

0.63

MRPL30

51263

Q8TCC3

0.63

MRPL27

51264

Q9P0M9

0.63

MRPL48

51642

Q96GC5

0.63

MRPS33

51650

Q9Y291

0.63

TUBA8

51807

Q9NY65

0.63

MRPL50

54534

Q8N5N7

0.63

TEX10

54881

Q9NXF1

0.63

MRPL16

54948

Q9NX20

0.63

PTCD3

55037

Q96EY7

0.63

MRPL20

55052

Q9BYC9

0.63

MRPS18A

55168

Q9NVS2

0.63

PPAN

56342

Q9NQ55

0.63

MRPL47

57129

Q9HD33

0.63

MRPL17

63875

Q9NRX2

0.63

MRPS24

64951

Q96EL2

0.63

MRPS9

64965

P82933

0.63

MRPS5

64969

P82675

0.63

MRPL40

64976

Q9NQ50

0.63

MRPL38

64978

Q96DV4

0.63

MRPL34

64981

Q9BQ48

0.63

MRPL32

64983

Q9BYC8

0.63

MRPL9

65005

Q9BYD2

0.63

MRPL1

65008

Q9BYD6

0.63

CEP70

80321

Q8NHQ1

0.63

GADD45GIP1

90480

Q8TAE8

0.63

MRPL55

128308

Q7Z7F7

0.63

NSUN4

387338

Q96CB9

0.63

CSNK2A1

1457

P68400

0.70

RPL26

6154

P61254

0.73

NSA2

10412

O95478

0.73

RPL26L1

51121

Q9UNX3

0.73

RPL7A

6130

P62424

0.74

RPL15

6138

P61313

0.74

RPL18

6141

Q07020

0.74

RPL19

6143

P84098

0.74

RPL21

6144

P46778

0.74

RPL23A

6147

P62750

0.74

RPL24

6152

P83731

0.74

RPLP0

6175

P05388

0.74

RPL36

25873

Q9Y3U8

0.74

RPL10

6134

P27635

0.82

ILF3

3609

Q12906

0.49

RPL3

6122

P39023

0.49

RPL3L

6123

Q92901

0.49

RPL18A

6142

Q02543

0.49

RPL31

6160

P62899

0.49

RPL38

6169

P63173

0.49

RPS10

6204

P46783

0.49

RPS11

6205

P62280

0.49

RPS12

6206

P25398

0.49

RPS19

6223

P39019

0.49

UBA52

7311

P62987

0.49

RACK1

10399

P63244

0.49

MYL12A

10627

P19105

0.49

RPL35

11224

P42766

0.49

SRPK2

6733

P78362

0.52

PTEN

5728

P60484

0.56

RPL8

6132

P62917

0.56

SUMO1

7341

P63165

0.56

RPL10A

4736

P62906

0.59

RPL11

6135

P62913

0.59

RPL12

6136

P30050

0.59

PABPC1

26986

P11940

0.59

ANXA7

310

P20073

0.63

CD81

975

P60033

0.63

CDK2

1017

P24941

0.63

CDK5

1020

Q00535

0.63

MAPK14

1432

Q16539

0.63

CSNK1A1

1452

P48729

0.63

CSNK1E

1454

P49674

0.63

CSNK2A2

1459

P19784

0.63

CSNK2B

1460

P67870

0.63

DAXX

1616

Q9UER7

0.63

EIF2S1

1965

P05198

0.63

FN1

2335

P02751

0.63

SFN

2810

P31947

0.63

GSK3B

2932

P49841

0.63

ICAM1

3383

P05362

0.63

ITGA4

3676

P13612

0.63

JUN

3725

P05412

0.63

MCM2

4171

P49736

0.63

MDM2

4193

Q00987

0.63

MOV10

4343

Q9HCE1

0.63

NFX1

4799

Q12986

0.63

NTRK1

4914

P04629

0.63

PARK2

5071

O60260

0.63

PHKG2

5261

P15735

0.63

PRKAA1

5562

Q13131

0.63

PRKACB

5567

P22694

0.63

PRKCD

5580

Q05655

0.63

MAP2K3

5606

P46734

0.63

EIF2AK2

5610

P19525

0.63

RAD21

5885

O60216

0.63

RELA

5970

Q04206

0.63

RPS6KA1

6195

Q15418

0.63

RPS6KB2

6199

Q9UBS0

0.63

SPP1

6696

P10451

0.63

SRC

6714

P12931

0.63

STAU1

6780

O95793

0.63

TCF3

6929

P15923

0.63

TK1

7083

P04183

0.63

TP53

7157

P04637

0.63

TUBG1

7283

P23258

0.63

VCP

7415

P55072

0.63

YWHAZ

7534

P63104

0.63

GAN

8139

Q9H2C0

0.63

UBL4A

8266

P11441

0.63

STK24

8428

Q9Y6E0

0.63

CUL4B

8450

Q13620

0.63

CUL3

8452

Q13618

0.63

CUL2

8453

Q13617

0.63

CUL1

8454

Q13616

0.63

MAPKAPK5

8550

Q8IW41

0.63

EEF1E1

9521

O43324

0.63

KIAA0101

9768

Q15004

0.63

CUL7

9820

Q14999

0.63

PAN2

9924

Q504Q3

0.63

OXSR1

9943

O95747

0.63

HDAC5

10014

Q9UQL6

0.63

HUWE1

10075

Q7Z6Z7

0.63

NXF1

10482

Q9UBU9

0.63

NOP56

10528

O00567

0.63

AHSA1

10598

O95433

0.63

EBNA1BP2

10969

Q99848

0.63

COPS5

10987

Q92905

0.63

CEP250

11190

Q9BV73

0.63

GABARAP

11337

O95166

0.63

GABARAPL2

11345

P60520

0.63

SNW1

22938

Q13573

0.63

OBSL1

23363

O75147

0.63

TARDBP

23435

Q13148

0.63

TRIM29

23650

Q14134

0.63

GABARAPL1

23710

Q9H0R8

0.63

UPF2

26019

Q9HAU5

0.63

AGO1

26523

Q9UL18

0.63

TUBGCP4

27229

Q9UGJ1

0.63

STK26

51765

Q9P289

0.63

RIOK2

55781

Q9BVS4

0.63

CAND1

55832

Q86VP6

0.63

ZNF317

57693

Q96PQ6

0.63

NOM1

64434

Q5C9Z4

0.63

THAP7

80764

Q9BT49

0.63

MAP1LC3A

84557

Q9H492

0.63

IGSF8

93185

Q969P0

0.63

TP53RK

112858

Q96S44

0.63

NEDD1

121441

Q8NHV4

0.63

DCC

1630

P43146

0.72

HNRNPU

3192

Q00839

0.72

MAGOH

4116

P61326

0.72

MAP3K1

4214

Q13233

0.72

MYC

4609

P01106

0.72

NEDD8

4738

Q15843

0.72

NFKB2

4791

Q00653

0.72

NPM1

4869

P06748

0.72

MAP3K14

9020

Q99558

0.72

EIF4A3

9775

P38919

0.72

TBK1

29110

Q9UHD2

0.72

EXOSC4

54512

Q9NPD3

0.72

RICTOR

253260

Q6R327

0.72

RPS9

6203

P46781

0.73

IPO5

3843

O00410

0.75

TERF2

7014

Q15554

0.75

LRRK2

120892

Q5S007

0.75

ESR1

2099

P03372

0.77

ILK

3611

Q13418

0.82

VCAM1

7412

P19320

0.82

SMN1; SMN2

6606

Q16637

0.82

CDC5L

988

Q99459

0.87