Protein Description

Gene Symbol ABCE1
Entrez ID 6059
Uniprot ID P61221
Description ATP binding cassette subfamily E member 1
Chromosomal Location chr4: 145,097,932-145,129,179
Ontology GO ID GO Term Definition Evidence

BP

GO:0000054

ribosomal subunit export from nucleus

The directed movement of a ribosomal subunit from the nucleus into the cytoplasm.

IBA

BP

GO:0006413

translational initiation

The process preceding formation of the peptide bond between the first two amino acids of a protein. This includes the formation of a complex of the ribosome, mRNA, and an initiation complex that contains the first aminoacyl-tRNA.

IBA

BP

GO:0006415

translational termination

The process resulting in the release of a polypeptide chain from the ribosome, usually in response to a termination codon (UAA, UAG, or UGA in the universal genetic code).

IBA

BP

GO:0016032

viral process

A multi-organism process in which a virus is a participant. The other participant is the host. Includes infection of a host cell, replication of the viral genome, and assembly of progeny virus particles. In some cases the viral genetic material may integrate into the host genome and only subsequently, under particular circumstances, 'complete' its life cycle.

IEA

BP

GO:0055085

transmembrane transport

The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other

TAS

BP

GO:0060702

negative regulation of endoribonuclease activity

Any process that decreases the rate, frequency or extent of the catalysis of the hydrolysis of ester linkages within ribonucleic acid by creating internal breaks.

IDA

CC

GO:0005737

cytoplasm

All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

IDA

CC

GO:0005739

mitochondrion

A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.

IDA

CC

GO:0005759

mitochondrial matrix

The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation.

TAS

CC

GO:0005852

eukaryotic translation initiation factor 3 complex

A complex of several polypeptides that plays at least two important roles in protein synthesis: First, eIF3 binds to the 40S ribosome and facilitates loading of the Met-tRNA/eIF2.GTP ternary complex to form the 43S preinitiation complex. Subsequently, eIF3 apparently assists eIF4 in recruiting mRNAs to the 43S complex. The eIF3 complex contains five conserved core subunits, and may contain several additional proteins; the non-core subunits are thought to mediate association of the complex with specific sets of mRNAs.

IBA

CC

GO:0016020

membrane

A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.

IDA

MF

GO:0005506

iron ion binding

Interacting selectively and non-covalently with iron (Fe) ions.

IBA

MF

GO:0005515

protein binding

Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).

IPI

MF

GO:0005524

ATP binding

Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.

IBA

MF

GO:0016887

ATPase activity

Catalysis of the reaction: ATP + H2O = ADP + phosphate + 2 H+. May or may not be coupled to another reaction.

IEA

MF

GO:0043024

ribosomal small subunit binding

Interacting selectively and non-covalently with any part of the small ribosomal subunit.

IBA

MF

GO:0060698

endoribonuclease inhibitor activity

Stops, prevents or reduces the activity of an endoribonuclease, any enzyme that catalyzes the hydrolysis of ester linkages within ribonucleic acid by creating internal breaks.

IDA

Domain ID Description

IPR003439

ABC transporter-like

IPR003593

AAA+ ATPase domain

IPR007209

RNase L inhibitor RLI, possible metal-binding domain

IPR013283

RLI1

IPR017871

ABC transporter, conserved site

IPR017896

4Fe-4S ferredoxin-type, iron-sulphur binding domain

IPR017900

4Fe-4S ferredoxin, iron-sulphur binding, conserved site

IPR027417

P-loop containing nucleoside triphosphate hydrolase

IPR034348

RLI, domain 1

No pathways found.

UMLS CUI UMLS Term

C0009404

Colorectal Neoplasms

C0017661

Iga Glomerulonephritis

Tissue Cell Type

appendix

glandular cells

bone marrow

hematopoietic cells

breast

glandular cells

cerebellum

Purkinje cells

cerebral cortex

neuronal cells

colon

glandular cells

duodenum

glandular cells

endometrium

glandular cells

esophagus

squamous epithelial cells

fallopian tube

glandular cells

gallbladder

glandular cells

lung

macrophages

lymph node

non-germinal center cells

oral mucosa

squamous epithelial cells

ovary

follicle cells

pancreas

exocrine glandular cells

placenta

decidual cells

placenta

trophoblastic cells

rectum

glandular cells

salivary gland

glandular cells

skin

fibroblasts

skin

epidermal cells

small intestine

glandular cells

soft tissue

fibroblasts

stomach

glandular cells

testis

cells in seminiferous ducts

thyroid gland

glandular cells

tonsil

germinal center cells

tonsil

non-germinal center cells

tonsil

squamous epithelial cells

urinary bladder

urothelial cells

vagina

squamous epithelial cells

No databases found.

Pubmed ID Author Year Title

22617121

Ouandaogo et al.

2012

Differences in transcriptomic profiles of human cumulus cells isolated from oocytes at GV, MI and MII stages after in vivo andin vitro oocyte maturation

Gene Symbol Entrez ID Uniprot ID Score

RNASE2

6036

P10153

0.55

RPL4

6124

P36578

0.58

AARS

16

P49588

0.63

ABCF1

23

Q8NE71

0.63

ACAT1

38

P24752

0.63

AP1B1

162

Q10567

0.63

AK2

204

P54819

0.63

ANK2

287

Q01484

0.63

APEX1

328

P27695

0.63

ASNS

440

P08243

0.63

ATP6V1A

523

P38606

0.63

CACNA2D1

781

P54289

0.63

CBR3

874

O75828

0.63

CD44

960

P16070

0.63

CD59

966

P13987

0.63

TPP1

1200

O14773

0.63

CSTB

1476

P04080

0.63

DSG2

1829

Q14126

0.63

DUT

1854

P33316

0.63

EPB41

2035

P11171

0.63

EPB41L2

2037

O43491

0.63

EWSR1

2130

Q01844

0.63

FDPS

2224

P14324

0.63

FLNA

2316

P21333

0.63

FLNB

2317

O75369

0.63

FLOT2

2319

Q14254

0.63

FYN

2534

P06241

0.63

GLB1

2720

P16278

0.63

GNA11

2767

P29992

0.63

GNAQ

2776

P50148

0.63

GNAZ

2781

P19086

0.63

GNB1

2782

P62873

0.63

GNG5

2787

P63218

0.63

GNS

2799

P15586

0.63

PDIA3

2923

P30101

0.63

GSPT1

2935

P15170

0.63

HIST1H1C

3006

P16403

0.63

HEXB

3074

P07686

0.63

HSPE1

3336

P61604

0.63

IGF2R

3482

P11717

0.63

JUP

3728

P14923

0.63

KARS

3735

Q15046

0.63

KIF5B

3799

P33176

0.63

ABLIM1

3983

O14639

0.63

LMNA

4000

P02545

0.63

LMNB1

4001

P20700

0.63

LYN

4067

P07948

0.63

MAP1B

4131

P46821

0.63

MAP4

4134

P27816

0.63

MFGE8

4240

Q08431

0.63

MSN

4478

P26038

0.63

MYO6

4646

Q9UM54

0.63

NDUFA4

4697

O00483

0.63

NDUFA5

4698

Q16718

0.63

PNP

4860

P00491

0.63

NUMA1

4926

Q14980

0.63

NUP98

4928

P52948

0.63

PEBP1

5037

P30086

0.63

PAK3

5063

O75914

0.63

PDHA1

5160

P08559

0.63

PFDN2

5202

Q9UHV9

0.63

PFKL

5211

P17858

0.63

CTSA

5476

P10619

0.63

PPM1G

5496

O15355

0.63

PPP1CB

5500

P62140

0.63

PPP1CC

5501

P36873

0.63

PPP2R2A

5520

P63151

0.63

PPP6C

5537

O00743

0.63

PRCP

5547

P42785

0.63

PRKACA

5566

P17612

0.63

PRKAR2A

5576

P13861

0.63

MAPK1

5594

P28482

0.63

PSMA2

5683

P25787

0.63

PSMA5

5686

P28066

0.63

PSMB3

5691

P49720

0.63

PSMC2

5701

P35998

0.63

PSMD1

5707

Q99460

0.63

PSMD4

5710

P55036

0.63

PSMD8

5714

P48556

0.63

PSMD13

5719

Q9UNM6

0.63

TWF1

5756

Q12792

0.63

PTPRF

5792

P10586

0.63

RALA

5898

P11233

0.63

RAP2B

5912

P61225

0.63

RBBP7

5931

Q16576

0.63

RFC4

5984

P35249

0.63

ABCE1

6059

P61221

0.63

RP2

6102

O75695

0.63

RPL21

6144

P46778

0.63

RPL32

6161

P62910

0.63

RPL35A

6165

P18077

0.63

RPS12

6206

P25398

0.63

RPS25

6230

P62851

0.63

RPS27

6232

P42677

0.63

RPS29

6235

P62273

0.63

S100A10

6281

P60903

0.63

SAFB

6294

Q15424

0.63

SDHB

6390

P21912

0.63

SNRPF

6636

P62306

0.63

SRC

6714

P12931

0.63

SRM

6723

P19623

0.63

SSFA2

6744

P28290

0.63

SURF4

6836

O15260

0.63

TBCD

6904

Q9BTW9

0.63

TCEB1

6921

Q15369

0.63

TFAM

7019

Q00059

0.63

TMPO

7112

P42166

0.63

TP53

7157

P04637

0.63

TSN

7247

Q15631

0.63

DNAJC7

7266

Q99615

0.63

VDAC2

7417

P45880

0.63

VDAC3

7419

Q9Y277

0.63

VIM

7431

P08670

0.63

YWHAH

7533

Q04917

0.63

ZNF207

7756

O43670

0.63

USP7

7874

Q93009

0.63

SMC1A

8243

Q14683

0.63

NAA10

8260

P41227

0.63

CUL4A

8451

Q13619

0.63

SMARCA5

8467

O60264

0.63

DYNLL1

8655

P63167

0.63

EIF3D

8664

O15371

0.63

SNAP23

8773

O00161

0.63

SUCLG2

8801

Q96I99

0.63

IQGAP1

8826

P46940

0.63

FUBP3

8939

Q96I24

0.63

AIFM1

9131

O95831

0.63

MED23

9439

Q9ULK4

0.63

TECR

9524

Q9NZ01

0.63

TTC37

9652

Q6PGP7

0.63

EIF4A3

9775

P38919

0.63

TOMM20

9804

Q15388

0.63

DDX46

9879

Q7L014

0.63

WDR1

9948

O75083

0.63

HDAC6

10013

Q9UBN7

0.63

SMC4

10051

Q9NTJ3

0.63

SAE1

10055

Q9UBE0

0.63

ARPC5

10092

O15511

0.63

FLOT1

10211

O75955

0.63

PSMD14

10213

O00487

0.63

SF3A1

10291

Q15459

0.63

HMGB1P1

10357

B2RPK0

0.63

HAX1

10456

O00165

0.63

EBP

10682

Q15125

0.63

PTGES3

10728

Q15185

0.63

IMMT

10989

Q16891

0.63

RAB35

11021

Q15286

0.63

PSIP1

11168

O75475

0.63

STRAP

11171

Q9Y3F4

0.63

SUPT16H

11198

Q9Y5B9

0.63

ATXN2L

11273

Q8WWM7

0.63

CBX3

11335

Q13185

0.63

MAPRE1

22919

Q15691

0.63

RRP1B

23076

Q14684

0.63

PEG10

23089

Q86TG7

0.63

EPB41L3

23136

Q9Y2J2

0.63

MDN1

23195

Q9NU22

0.63

UFL1

23376

O94874

0.63

CBX5

23468

P45973

0.63

MACF1

23499

Q9UPN3

0.63

SRRM2

23524

Q9UQ35

0.63

CORO1C

23603

Q9ULV4

0.63

ATXN10

25814

Q9UBB4

0.63

RPL36

25873

Q9Y3U8

0.63

NDUFAF4

29078

Q9P032

0.63

TIMM21

29090

Q9BVV7

0.63

CNIH4

29097

Q9P003

0.63

NDUFA13

51079

Q9P0J0

0.63

SDF4

51150

Q9BRK5

0.63

DCXR

51181

Q7Z4W1

0.63

ISYNA1

51477

Q9NPH2

0.63

C14orf166

51637

Q9Y224

0.63

CPSF3

51692

Q9UKF6

0.63

CPVL

54504

Q9H3G5

0.63

EXOSC4

54512

Q9NPD3

0.63

FANCI

55215

Q9NVI1

0.63

CISD1

55847

Q9NZ45

0.63

DIABLO

56616

Q9NR28

0.63

YAE1D1

57002

Q9NRH1

0.63

STARD9

57519

Q9P2P6

0.63

KIAA1524

57650

Q8TCG1

0.63

RPRD1B

58490

Q9NQG5

0.63

GNB4

59345

Q9HAV0

0.63

WDR77

79084

Q9BQA1

0.63

ULBP3

79465

Q9BZM4

0.63

C2orf47

79568

Q8WWC4

0.63

HM13

81502

Q8TCT9

0.63

AIF1L

83543

Q9BQI0

0.63

TTC29

83894

Q8NA56

0.63

POLR1B

84172

Q9H9Y6

0.63

LMNB2

84823

Q03252

0.63

GADD45GIP1

90480

Q8TAE8

0.63

SFXN4

119559

Q6P4A7

0.63

RAVER1

125950

Q8IY67

0.63

CCNY

219771

Q8ND76

0.63

ORAOV1

220064

Q8WV07

0.63

GAS2L3

283431

Q86XJ1

0.63

C16orf96

342346

A6NNT2

0.63

H3F3C

440093

Q6NXT2

0.63

HIST2H2BF

440689

Q5QNW6

0.63

SRP9

653226

P49458

0.63

TIMM23

100287932

O14925

0.63

SLC25A4

291

P12235

0.70

DKC1

1736

O60832

0.70

FBL

2091

P22087

0.70

ETF1

2107

P62495

0.70

DDX18

8886

Q9NVP1

0.70

RRP12

23223

Q5JTH9

0.70

NAT10

55226

Q9H0A0

0.70

RNASEL

6041

Q05823

0.75

VAPB

9217

O95292

0.49

VAPA

9218

Q9P0L0

0.49

PTER

9317

Q96BW5

0.49

TMEM216

51259

Q9P0N5

0.49

CENPJ

55835

Q9HC77

0.49

POC5

134359

Q8NA72

0.49

TMEM17

200728

Q86X19

0.49

RPL7

6129

P18124

0.56

RPS3A

6189

P61247

0.56

ITGA4

3676

P13612

0.63

JUN

3725

P05412

0.63

MCM2

4171

P49736

0.63

NTRK1

4914

P04629

0.63

PARK2

5071

O60260

0.63

RNF2

6045

Q99496

0.63

SUMO2

6613

P61956

0.63

STAU1

6780

O95793

0.63

VCAM1

7412

P19320

0.63

XPO1

7514

O14980

0.63

CUL3

8452

Q13618

0.63

FBXO6

26270

Q9NRD1

0.63

SIRT7

51547

Q9NRC8

0.63

FAM96B

51647

Q9Y3D0

0.63

UBASH3A

53347

P57075

0.63

LRRK2

120892

Q5S007

0.63

DCP2

167227

Q8IU60

0.63

ILK

3611

Q13418

0.72

XRCC5

7520

P13010

0.72

EIF3F

8665

O00303

0.72

CIAO1

9391

O76071

0.73

MMS19

64210

Q96T76

0.73

EIF3H

8667

O15372

0.76

USP50

373509

Q70EL3

0.76