BP

GO:0001934

positive regulation of protein phosphorylation

Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to amino acids within a protein.

IMP

BP

GO:0030033

microvillus assembly

Formation of a microvillus, a thin cylindrical membrane-covered projection on the surface of a cell.

IMP

BP

GO:0030336

negative regulation of cell migration

Any process that stops, prevents, or reduces the frequency, rate or extent of cell migration.

IEA

BP

GO:0031532

actin cytoskeleton reorganization

A process that is carried out at the cellular level which results in dynamic structural changes to the arrangement of constituent parts of cytoskeletal structures comprising actin filaments and their associated proteins.

IDA

BP

GO:0031954

positive regulation of protein autophosphorylation

Any process that activates or increases the frequency, rate or extent of the phosphorylation by a protein of one or more of its own residues.

IDA

BP

GO:0032486

Rap protein signal transduction

A series of molecular signals within the cell that are mediated by a member of the Rap family of proteins switching to a GTP-bound active state.

ISS

BP

GO:0034613

cellular protein localization

Any process in which a protein is transported to, and/or maintained in, a specific location at the level of a cell. Localization at the cellular level encompasses movement within the cell, from within the cell to the cell surface, or from one location to another at the surface of a cell.

IDA

BP

GO:0035690

cellular response to drug

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a drug stimulus. A drug is a substance used in the diagnosis, treatment or prevention of a disease.

IDA

BP

GO:0045184

establishment of protein localization

The directed movement of a protein to a specific location.

IDA

BP

GO:0046328

regulation of JNK cascade

Any process that modulates the frequency, rate or extent of signal transduction mediated by the JNK cascade.

IDA

BP

GO:0048814

regulation of dendrite morphogenesis

Any process that modulates the frequency, rate or extent of dendrite morphogenesis.

IDA

BP

GO:0072659

protein localization to plasma membrane

A process in which a protein is transported to, or maintained in, a specific location in the plasma membrane.

IMP

CC

GO:0005829

cytosol

The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

IEA

CC

GO:0005886

plasma membrane

The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

IDA

CC

GO:0030496

midbody

A thin cytoplasmic bridge formed between daughter cells at the end of cytokinesis. The midbody forms where the contractile ring constricts, and may persist for some time before finally breaking to complete cytokinesis.

IEA

CC

GO:0055037

recycling endosome

An organelle consisting of a network of tubules that functions in targeting molecules, such as receptors transporters and lipids, to the plasma membrane.

IDA

CC

GO:0055038

recycling endosome membrane

The lipid bilayer surrounding a recycling endosome.

IDA

CC

GO:0070062

extracellular exosome

A membrane-bounded vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.

IDA

MF

GO:0003924

GTPase activity

Catalysis of the reaction: GTP + H2O = GDP + phosphate.

IDA

MF

GO:0005515

protein binding

Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).

IPI

MF

GO:0005525

GTP binding

Interacting selectively and non-covalently with GTP, guanosine triphosphate.

IDA