BP

GO:0000413

protein peptidyl-prolyl isomerization

The modification of a protein by cis-trans isomerization of a proline residue.

IEA

BP

GO:0001975

response to amphetamine

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amphetamine stimulus. Amphetamines consist of a group of compounds related to alpha-methylphenethylamine.

IEA

BP

GO:0006406

mRNA export from nucleus

The directed movement of mRNA from the nucleus to the cytoplasm.

TAS

BP

GO:0006409

tRNA export from nucleus

The directed movement of tRNA from the nucleus to the cytoplasm.

TAS

BP

GO:0006457

protein folding

The process of assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure.

IEA

BP

GO:0006607

NLS-bearing protein import into nucleus

The directed movement of a protein bearing a nuclear localization signal (NLS) from the cytoplasm into the nucleus, across the nuclear membrane.

IMP

BP

GO:0007062

sister chromatid cohesion

The cell cycle process in which the sister chromatids of a replicated chromosome become tethered to each other.

TAS

BP

GO:0007077

mitotic nuclear envelope disassembly

The cell cycle process in which the controlled breakdown of the nuclear envelope during mitotic cell division occurs.

TAS

BP

GO:0010827

regulation of glucose transport

Any process that modulates the frequency, rate or extent of glucose transport. Glucose transport is the directed movement of the hexose monosaccharide glucose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

TAS

BP

GO:0016032

viral process

A multi-organism process in which a virus is a participant. The other participant is the host. Includes infection of a host cell, replication of the viral genome, and assembly of progeny virus particles. In some cases the viral genetic material may integrate into the host genome and only subsequently, under particular circumstances, 'complete' its life cycle.

TAS

BP

GO:0016925

protein sumoylation

The process in which a SUMO protein (small ubiquitin-related modifier) is conjugated to a target protein via an isopeptide bond between the carboxyl terminus of SUMO with an epsilon-amino group of a lysine residue of the target protein.

IDA|IEA|TAS

BP

GO:0019083

viral transcription

The process by which a viral genome, or part of a viral genome, is transcribed within the host cell.

TAS

BP

GO:0031047

gene silencing by RNA

Any process in which RNA molecules inactivate expression of target genes.

TAS

BP

GO:0033132

negative regulation of glucokinase activity

Any process that stops, prevents, or reduces the frequency, rate or extent of glucokinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a glucose molecule.

IBA

BP

GO:0075733

intracellular transport of virus

The directed movement of a virus, or part of a virus, within the host cell.

TAS

BP

GO:0090526

regulation of gluconeogenesis involved in cellular glucose homeostasis

Any process that modulates the frequency, rate or extent of gluconeogenesis as an integral part of cellular glucose homeostasis.

IBA

BP

GO:1900034

regulation of cellular response to heat

Any process that modulates the frequency, rate or extent of cellular response to heat.

TAS

CC

GO:0005635

nuclear envelope

The double lipid bilayer enclosing the nucleus and separating its contents from the rest of the cytoplasm; includes the intermembrane space, a gap of width 20-40 nm (also called the perinuclear space).

TAS

CC

GO:0005643

nuclear pore

Any of the numerous similar discrete openings in the nuclear envelope of a eukaryotic cell, where the inner and outer nuclear membranes are joined.

IDA

CC

GO:0005739

mitochondrion

A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.

IBA

CC

GO:0005829

cytosol

The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

TAS

CC

GO:0005875

microtubule associated complex

Any multimeric complex connected to a microtubule.

IBA

CC

GO:0016020

membrane

A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.

IDA

CC

GO:0031965

nuclear membrane

Either of the lipid bilayers that surround the nucleus and form the nuclear envelope; excludes the intermembrane space.

IDA

CC

GO:0042405

nuclear inclusion body

An intranuclear focus at which aggregated proteins have been sequestered.

IDA

CC

GO:0044614

nuclear pore cytoplasmic filaments

Filamentous extensions on cytoplasmic face of the nuclear pore complex (NPC). In S. cerevisiae, Nup159p, Nup82p, and Nup42p contribute to the cytoplasmic filaments. In vertebrates, Nup358 is a major component.

IDA

CC

GO:0044615

nuclear pore nuclear basket

A filamentous, cage-like assembly on the nuclear face of the nuclear pore complex (NPC). In S. cerevisiae, Mlp1p and Mlp2p are two major components of the NPC nuclear basket. In vertebrates, Tpr is a major component.

IDA

CC

GO:1990723

cytoplasmic periphery of the nuclear pore complex

Cytoplasm situated in close proximity to a nuclear pore complex.

IEA

MF

GO:0003723

RNA binding

Interacting selectively and non-covalently with an RNA molecule or a portion thereof.

IEA

MF

GO:0003755

peptidyl-prolyl cis-trans isomerase activity

Catalysis of the reaction: peptidyl-proline (omega=180) = peptidyl-proline (omega=0).

IEA

MF

GO:0005515

protein binding

Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).

IPI

MF

GO:0008270

zinc ion binding

Interacting selectively and non-covalently with zinc (Zn) ions.

IEA

MF

GO:0008536

Ran GTPase binding

Interacting selectively and non-covalently with Ran, a conserved Ras-like GTP-binding protein, implicated in nucleocytoplasmic transport, cell cycle progression, spindle assembly, nuclear organization and nuclear envelope (NE) assembly.

IPI

MF

GO:0016874

ligase activity

Catalysis of the joining of two substances, or two groups within a single molecule, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.

IEA

MF

GO:0019789

SUMO transferase activity

Catalysis of the transfer of SUMO from one protein to another via the reaction X-SUMO + Y --> Y-SUMO + X, where both X-SUMO and Y-SUMO are covalent linkages.

EXP

MF

GO:0032403

protein complex binding

Interacting selectively and non-covalently with any protein complex (a complex of two or more proteins that may include other nonprotein molecules).

IEA