Gene Symbol | PVR |
Entrez ID | 5817 |
Uniprot ID | P15151 |
Description | poliovirus receptor |
Chromosomal Location | chr19: 44,643,798-44,663,583 |
Ontology | GO ID | GO Term | Definition | Evidence |
---|---|---|---|---|
BP |
GO:0002860 |
positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target |
Any process that activates or increases the frequency, rate, or extent of natural killer cell mediated cytotoxicity directed against tumor cell target. |
IMP |
BP |
GO:0007156 |
homophilic cell adhesion via plasma membrane adhesion molecules |
The attachment of a plasma membrane adhesion molecule in one cell to an identical molecule in an adjacent cell. |
IBA |
BP |
GO:0007157 |
heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules |
The attachment of an adhesion molecule in one cell to a nonidentical adhesion molecule in an adjacent cell. |
IBA |
BP |
GO:0008037 |
cell recognition |
The process in which a cell in an organism interprets its surroundings. |
IBA |
BP |
GO:0034332 |
adherens junction organization |
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an adherens junction. An adherens junction is a cell junction at which the cytoplasmic face of the plasma membrane is attached to actin filaments. |
TAS |
BP |
GO:0042271 |
susceptibility to natural killer cell mediated cytotoxicity |
The process of causing a cell to become susceptible to natural killer cell mediated cytotoxicity. |
IMP |
BP |
GO:0045954 |
positive regulation of natural killer cell mediated cytotoxicity |
Any process that activates or increases the frequency, rate or extent of natural killer cell mediated cytotoxicity. |
IMP |
BP |
GO:0046718 |
viral entry into host cell |
The process that occurs after viral attachment by which a virus, or viral nucleic acid, breaches the plasma membrane or cell envelope and enters the host cell. The process ends when the viral nucleic acid is released into the host cell cytoplasm. |
IEA |
BP |
GO:0050776 |
regulation of immune response |
Any process that modulates the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus. |
TAS |
BP |
GO:0060370 |
susceptibility to T cell mediated cytotoxicity |
The process of causing a cell to become susceptible to T cell mediated cytotoxicity. |
IDA |
CC |
GO:0005615 |
extracellular space |
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid. |
TAS |
CC |
GO:0005737 |
cytoplasm |
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
TAS |
CC |
GO:0005886 |
plasma membrane |
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
TAS |
CC |
GO:0005887 |
integral component of plasma membrane |
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
IBA |
CC |
GO:0005913 |
cell-cell adherens junction |
An adherens junction which connects a cell to another cell. |
IBA |
CC |
GO:0005925 |
focal adhesion |
Small region on the surface of a cell that anchors the cell to the extracellular matrix and that forms a point of termination of actin filaments. |
IDA |
CC |
GO:0009986 |
cell surface |
The external part of the cell wall and/or plasma membrane. |
IDA |
CC |
GO:0016021 |
integral component of membrane |
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
IDA |
CC |
GO:0070062 |
extracellular exosome |
A membrane-bounded vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm. |
IDA |
MF |
GO:0001618 |
virus receptor activity |
Combining with a virus component and mediating entry of the virus into the cell. |
IEA |
MF |
GO:0004872 |
receptor activity |
Combining with an extracellular or intracellular messenger to initiate a change in cell activity. |
TAS |
MF |
GO:0005102 |
receptor binding |
Interacting selectively and non-covalently with one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function. |
IBA |
MF |
GO:0005515 |
protein binding |
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules). |
IPI |
MF |
GO:0042803 |
protein homodimerization activity |
Interacting selectively and non-covalently with an identical protein to form a homodimer. |
IBA |
MF |
GO:0050839 |
cell adhesion molecule binding |
Interacting selectively and non-covalently with a cell adhesion molecule. |
IPI |
Domain ID | Description |
---|---|
IPR003599 |
Immunoglobulin subtype |
IPR007110 |
Immunoglobulin-like domain |
IPR013106 |
Immunoglobulin V-set domain |
IPR013162 |
CD80-like, immunoglobulin C2-set |
IPR013783 |
Immunoglobulin-like fold |
Pathway ID | Pathway Term | Pathway Source |
---|---|---|
hsa04514 |
Cell adhesion molecules (CAMs) |
KEGG |
UMLS CUI | UMLS Term |
---|---|
C0026769 |
Multiple Sclerosis |
C0032371 |
Poliomyelitis |
Tissue | Cell Type |
---|---|
heart muscle |
myocytes |
placenta |
decidual cells |
testis |
Leydig cells |
Pubmed ID | Author | Year | Title |
---|---|---|---|
22617121 |
Ouandaogo et al. |
2012 |
Differences in transcriptomic profiles of human cumulus cells isolated from oocytes at GV, MI and MII stages after in vivo andin vitro oocyte maturation |
Gene Symbol | Entrez ID | Uniprot ID | Score |
---|---|---|---|
ZC3HAV1 |
56829 |
Q7Z2W4 |
0.49 |
PVR |
5817 |
P15151 |
0.52 |
TJP1 |
7082 |
Q07157 |
0.52 |
SLC30A2 |
7780 |
Q9BRI3 |
0.63 |
KRTAP10-7 |
386675 |
P60409 |
0.63 |
KRTAP10-9 |
386676 |
P60411 |
0.63 |
KRTAP10-8 |
386681 |
P60410 |
0.63 |
KRTAP10-3 |
386682 |
P60369 |
0.63 |
NOTCH2NL |
388677 |
Q7Z3S9 |
0.63 |
DYNLT1 |
6993 |
P63172 |
0.76 |
CDH1 |
999 |
P12830 |
0.52 |
NECTIN1 |
5818 |
Q15223 |
0.52 |
TNFRSF12A |
51330 |
Q9NP84 |
0.56 |
DYNLT3 |
6990 |
P51808 |
0.62 |
ELAVL1 |
1994 |
Q15717 |
0.63 |
PLA2G3 |
50487 |
Q9NZ20 |
0.63 |
WNK1 |
65125 |
Q9H4A3 |
0.63 |
TIGIT |
201633 |
Q495A1 |
0.68 |
AP1M2 |
10053 |
Q9Y6Q5 |
0.75 |
CD96 |
10225 |
P40200 |
0.75 |
VTN |
7448 |
P04004 |
0.85 |
NECTIN3 |
25945 |
Q9NQS3 |
0.85 |
CD226 |
10666 |
Q15762 |
0.87 |