| Gene Symbol | ATP5G2 |
| Entrez ID | 517 |
| Uniprot ID | Q06055 |
| Description | ATP synthase, H+ transporting, mitochondrial Fo complex subunit C2 (subunit 9) |
| Chromosomal Location | chr12: 53,632,726-53,677,408 |
| Ontology | GO ID | GO Term | Definition | Evidence |
|---|---|---|---|---|
|
BP |
GO:0006754 |
ATP biosynthetic process |
The chemical reactions and pathways resulting in the formation of ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
TAS |
|
BP |
GO:0015986 |
ATP synthesis coupled proton transport |
The transport of protons across a membrane to generate an electrochemical gradient (proton-motive force) that powers ATP synthesis. |
IBA |
|
BP |
GO:0015991 |
ATP hydrolysis coupled proton transport |
The transport of protons against an electrochemical gradient, using energy from ATP hydrolysis. |
IEA |
|
BP |
GO:0042776 |
mitochondrial ATP synthesis coupled proton transport |
The transport of protons across a mitochondrial membrane to generate an electrochemical gradient (proton-motive force) that powers ATP synthesis. |
TAS |
|
CC |
GO:0000276 |
mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) |
All non-F1 subunits of the mitochondrial hydrogen-transporting ATP synthase, including integral and peripheral mitochondrial inner membrane proteins. |
IBA |
|
CC |
GO:0005741 |
mitochondrial outer membrane |
The outer, i.e. cytoplasm-facing, lipid bilayer of the mitochondrial envelope. |
TAS |
|
CC |
GO:0005753 |
mitochondrial proton-transporting ATP synthase complex |
A proton-transporting ATP synthase complex found in the mitochondrial membrane. |
TAS |
|
CC |
GO:0016021 |
integral component of membrane |
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
IEA |
|
MF |
GO:0005215 |
transporter activity |
Enables the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells. |
NAS |
|
MF |
GO:0008289 |
lipid binding |
Interacting selectively and non-covalently with a lipid. |
IEA |
|
MF |
GO:0046933 |
proton-transporting ATP synthase activity, rotational mechanism |
Catalysis of the transfer of protons from one side of a membrane to the other according to the reaction: ADP + H2O + phosphate + H+(in) = ATP + H+(out), by a rotational mechanism. |
IBA |
| Domain ID | Description |
|---|---|
|
IPR000454 |
ATP synthase, F0 complex, subunit C |
|
IPR002379 |
V-ATPase proteolipid subunit C-like domain |
|
IPR020537 |
ATP synthase, F0 complex, subunit C, DCCD-binding site |
| Pathway ID | Pathway Term | Pathway Source |
|---|---|---|
|
hsa00190 |
Oxidative phosphorylation |
KEGG |
|
hsa01100 |
Metabolic pathways |
KEGG |
|
hsa05010 |
Alzheimer's disease |
KEGG |
|
hsa05012 |
Parkinson's disease |
KEGG |
|
hsa05016 |
Huntington's disease |
KEGG |
|
WP111 |
Electron Transport Chain |
WikiPathways |
|
WP623 |
Oxidative phosphorylation |
WikiPathways |
| Tissue | Cell Type |
|---|---|
|
cerebral cortex |
endothelial cells |
|
cervix, uterine |
glandular cells |
|
colon |
glandular cells |
|
duodenum |
glandular cells |
|
gallbladder |
glandular cells |
|
kidney |
cells in tubules |
|
nasopharynx |
respiratory epithelial cells |
|
pancreas |
exocrine glandular cells |
|
prostate |
glandular cells |
|
rectum |
glandular cells |
|
small intestine |
glandular cells |
|
smooth muscle |
smooth muscle cells |
|
stomach |
glandular cells |
|
testis |
Leydig cells |
| Pubmed ID | Author | Year | Title |
|---|---|---|---|
|
22951915 |
Haozi et al. |
2012 |
Altered gene expression profile in cumulus cells of mature MII oocytes from patients with polycystic ovary syndrome |
| Gene Symbol | Entrez ID | Uniprot ID | Score |
|---|---|---|---|
|
ATP13A2 |
23400 |
Q9NQ11 |
0.72 |
|
TDP2 |
51567 |
O95551 |
0.63 |
|
XRN1 |
54464 |
Q8IZH2 |
0.63 |