Protein Description

Gene Symbol ATP5G2
Entrez ID 517
Uniprot ID Q06055
Description ATP synthase, H+ transporting, mitochondrial Fo complex subunit C2 (subunit 9)
Chromosomal Location chr12: 53,632,726-53,677,408
Ontology GO ID GO Term Definition Evidence

BP

GO:0006754

ATP biosynthetic process

The chemical reactions and pathways resulting in the formation of ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.

TAS

BP

GO:0015986

ATP synthesis coupled proton transport

The transport of protons across a membrane to generate an electrochemical gradient (proton-motive force) that powers ATP synthesis.

IBA

BP

GO:0015991

ATP hydrolysis coupled proton transport

The transport of protons against an electrochemical gradient, using energy from ATP hydrolysis.

IEA

BP

GO:0042776

mitochondrial ATP synthesis coupled proton transport

The transport of protons across a mitochondrial membrane to generate an electrochemical gradient (proton-motive force) that powers ATP synthesis.

TAS

CC

GO:0000276

mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)

All non-F1 subunits of the mitochondrial hydrogen-transporting ATP synthase, including integral and peripheral mitochondrial inner membrane proteins.

IBA

CC

GO:0005741

mitochondrial outer membrane

The outer, i.e. cytoplasm-facing, lipid bilayer of the mitochondrial envelope.

TAS

CC

GO:0005753

mitochondrial proton-transporting ATP synthase complex

A proton-transporting ATP synthase complex found in the mitochondrial membrane.

TAS

CC

GO:0016021

integral component of membrane

The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

IEA

MF

GO:0005215

transporter activity

Enables the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells.

NAS

MF

GO:0008289

lipid binding

Interacting selectively and non-covalently with a lipid.

IEA

MF

GO:0046933

proton-transporting ATP synthase activity, rotational mechanism

Catalysis of the transfer of protons from one side of a membrane to the other according to the reaction: ADP + H2O + phosphate + H+(in) = ATP + H+(out), by a rotational mechanism.

IBA

Domain ID Description

IPR000454

ATP synthase, F0 complex, subunit C

IPR002379

V-ATPase proteolipid subunit C-like domain

IPR020537

ATP synthase, F0 complex, subunit C, DCCD-binding site

Pathway ID Pathway Term Pathway Source

hsa00190

Oxidative phosphorylation

KEGG

hsa01100

Metabolic pathways

KEGG

hsa05010

Alzheimer's disease

KEGG

hsa05012

Parkinson's disease

KEGG

hsa05016

Huntington's disease

KEGG

WP111

Electron Transport Chain

WikiPathways

WP623

Oxidative phosphorylation

WikiPathways

No diseases found.

Tissue Cell Type

cerebral cortex

endothelial cells

cervix, uterine

glandular cells

colon

glandular cells

duodenum

glandular cells

gallbladder

glandular cells

kidney

cells in tubules

nasopharynx

respiratory epithelial cells

pancreas

exocrine glandular cells

prostate

glandular cells

rectum

glandular cells

small intestine

glandular cells

smooth muscle

smooth muscle cells

stomach

glandular cells

testis

Leydig cells

No databases found.

Pubmed ID Author Year Title

22951915

Haozi et al.

2012

Altered gene expression profile in cumulus cells of mature MII oocytes from patients with polycystic ovary syndrome

Gene Symbol Entrez ID Uniprot ID Score

ATP13A2

23400

Q9NQ11

0.72

TDP2

51567

O95551

0.63

XRN1

54464

Q8IZH2

0.63