BP

GO:0006119

oxidative phosphorylation

The phosphorylation of ADP to ATP that accompanies the oxidation of a metabolite through the operation of the respiratory chain. Oxidation of compounds establishes a proton gradient across the membrane, providing the energy for ATP synthesis.

NAS

BP

GO:0006754

ATP biosynthetic process

The chemical reactions and pathways resulting in the formation of ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.

NAS|TAS

BP

GO:0015986

ATP synthesis coupled proton transport

The transport of protons across a membrane to generate an electrochemical gradient (proton-motive force) that powers ATP synthesis.

IBA

BP

GO:0042776

mitochondrial ATP synthesis coupled proton transport

The transport of protons across a mitochondrial membrane to generate an electrochemical gradient (proton-motive force) that powers ATP synthesis.

IC|NAS|TAS

BP

GO:0046688

response to copper ion

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a copper ion stimulus.

NAS

CC

GO:0000275

mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)

The catalytic sector of the mitochondrial hydrogen-transporting ATP synthase; it comprises the catalytic core and central stalk, and is peripherally associated with the mitochondrial inner membrane when the entire ATP synthase is assembled.

IBA|NAS

CC

GO:0005739

mitochondrion

A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.

NAS

CC

GO:0005743

mitochondrial inner membrane

The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae.

ISS

CC

GO:0005753

mitochondrial proton-transporting ATP synthase complex

A proton-transporting ATP synthase complex found in the mitochondrial membrane.

IDA|NAS

CC

GO:0005759

mitochondrial matrix

The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation.

TAS

MF

GO:0005215

transporter activity

Enables the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells.

NAS

MF

GO:0005524

ATP binding

Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.

NAS

MF

GO:0016887

ATPase activity

Catalysis of the reaction: ATP + H2O = ADP + phosphate + 2 H+. May or may not be coupled to another reaction.

IDA

MF

GO:0022857

transmembrane transporter activity

Enables the transfer of a substance from one side of a membrane to the other.

IC

MF

GO:0043531

ADP binding

Interacting selectively and non-covalently with ADP, adenosine 5'-diphosphate.

NAS

MF

GO:0046933

proton-transporting ATP synthase activity, rotational mechanism

Catalysis of the transfer of protons from one side of a membrane to the other according to the reaction: ADP + H2O + phosphate + H+(in) = ATP + H+(out), by a rotational mechanism.

IBA

MF

GO:0046961

proton-transporting ATPase activity, rotational mechanism

Catalysis of the transfer of protons from one side of a membrane to the other according to the reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out), by a rotational mechanism.

IEA