| Gene Symbol | PPM1G |
| Entrez ID | 5496 |
| Uniprot ID | O15355 |
| Description | protein phosphatase, Mg2+/Mn2+ dependent 1G |
| Chromosomal Location | chr2: 27,381,194-27,409,687 |
| Ontology | GO ID | GO Term | Definition | Evidence |
|---|---|---|---|---|
|
BP |
GO:0006470 |
protein dephosphorylation |
The process of removing one or more phosphoric residues from a protein. |
TAS |
|
BP |
GO:0007050 |
cell cycle arrest |
A regulatory process that halts progression through the cell cycle during one of the normal phases (G1, S, G2, M). |
IEA |
|
BP |
GO:0035970 |
peptidyl-threonine dephosphorylation |
The removal of phosphoric residues from peptidyl-O-phospho-L-threonine to form peptidyl-threonine. |
IDA |
|
CC |
GO:0005634 |
nucleus |
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
TAS |
|
CC |
GO:0005654 |
nucleoplasm |
That part of the nuclear content other than the chromosomes or the nucleolus. |
IDA |
|
CC |
GO:0005737 |
cytoplasm |
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
IEA |
|
CC |
GO:0016020 |
membrane |
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it. |
IEA |
|
MF |
GO:0004722 |
protein serine/threonine phosphatase activity |
Catalysis of the reaction: protein serine phosphate + H2O = protein serine + phosphate, and protein threonine phosphate + H2O = protein threonine + phosphate. |
IDA |
|
MF |
GO:0046872 |
metal ion binding |
Interacting selectively and non-covalently with any metal ion. |
IEA |
| Domain ID | Description |
|---|---|
|
IPR000222 |
PPM-type phosphatase, divalent cation binding |
|
IPR001932 |
PPM-type phosphatase domain |
|
IPR015655 |
Protein phosphatase 2C family |
| Pathway ID | Pathway Term | Pathway Source |
|---|---|---|
|
WP411 |
mRNA Processing |
WikiPathways |
| Tissue | Cell Type |
|---|---|
|
adrenal gland |
glandular cells |
|
bone marrow |
hematopoietic cells |
|
breast |
adipocytes |
|
breast |
glandular cells |
|
breast |
myoepithelial cells |
|
bronchus |
respiratory epithelial cells |
|
cerebellum |
Purkinje cells |
|
cerebral cortex |
neuronal cells |
|
cervix, uterine |
squamous epithelial cells |
|
colon |
endothelial cells |
|
colon |
glandular cells |
|
colon |
peripheral nerve/ganglion |
|
duodenum |
glandular cells |
|
esophagus |
squamous epithelial cells |
|
kidney |
cells in glomeruli |
|
kidney |
cells in tubules |
|
liver |
bile duct cells |
|
liver |
hepatocytes |
|
lymph node |
germinal center cells |
|
nasopharynx |
respiratory epithelial cells |
|
oral mucosa |
squamous epithelial cells |
|
pancreas |
exocrine glandular cells |
|
rectum |
glandular cells |
|
salivary gland |
glandular cells |
|
skeletal muscle |
myocytes |
|
skin |
fibroblasts |
|
skin |
Langerhans |
|
skin |
melanocytes |
|
skin |
epidermal cells |
|
small intestine |
glandular cells |
|
soft tissue |
adipocytes |
|
soft tissue |
chondrocytes |
|
soft tissue |
fibroblasts |
|
soft tissue |
peripheral nerve |
|
stomach |
glandular cells |
|
testis |
cells in seminiferous ducts |
|
testis |
Leydig cells |
|
thyroid gland |
glandular cells |
|
tonsil |
germinal center cells |
|
tonsil |
squamous epithelial cells |
|
urinary bladder |
urothelial cells |
|
vagina |
squamous epithelial cells |
| Pubmed ID | Author | Year | Title |
|---|---|---|---|
|
22617121 |
Ouandaogo et al. |
2012 |
Differences in transcriptomic profiles of human cumulus cells isolated from oocytes at GV, MI and MII stages after in vivo andin vitro oocyte maturation |
| Gene Symbol | Entrez ID | Uniprot ID | Score |
|---|---|---|---|
|
STMN1 |
3925 |
P16949 |
0.49 |
|
PSMA1 |
5682 |
P25786 |
0.49 |
|
S100P |
6286 |
P25815 |
0.49 |
|
SPR |
6697 |
P35270 |
0.49 |
|
STAT6 |
6778 |
P42226 |
0.49 |
|
SULT1A1 |
6817 |
P50225 |
0.49 |
|
THOP1 |
7064 |
P52888 |
0.49 |
|
TLE3 |
7090 |
Q04726 |
0.49 |
|
STAM |
8027 |
Q92783 |
0.49 |
|
SNX3 |
8724 |
O60493 |
0.49 |
|
PAIP1 |
10605 |
Q9H074 |
0.49 |
|
UBE2C |
11065 |
O00762 |
0.49 |
|
STMN2 |
11075 |
Q93045 |
0.49 |
|
MED4 |
29079 |
Q9NPJ6 |
0.49 |
|
SNX12 |
29934 |
Q9UMY4 |
0.49 |
|
SRXN1 |
140809 |
Q9BYN0 |
0.49 |
|
TTC9C |
283237 |
Q8N5M4 |
0.49 |
|
SBK1 |
388228 |
Q52WX2 |
0.49 |
|
GRIA3 |
2892 |
P42263 |
0.55 |
|
AHCYL1 |
10768 |
O43865 |
0.59 |
|
CARS |
833 |
P49589 |
0.63 |
|
GARS |
2617 |
P41250 |
0.63 |
|
YBX1 |
4904 |
P67809 |
0.63 |
|
SNRPA |
6626 |
P09012 |
0.63 |
|
TROVE2 |
6738 |
P10155 |
0.63 |
|
TTC1 |
7265 |
Q99614 |
0.63 |
|
HIRIP3 |
8479 |
Q9BW71 |
0.63 |
|
HSPH1 |
10808 |
Q92598 |
0.63 |
|
PUF60 |
22827 |
Q9UHX1 |
0.63 |
|
XPO7 |
23039 |
Q9UIA9 |
0.63 |
|
CAND1 |
55832 |
Q86VP6 |
0.63 |
|
MAPK14 |
1432 |
Q16539 |
0.49 |
|
EWSR1 |
2130 |
Q01844 |
0.49 |
|
LMNA |
4000 |
P02545 |
0.49 |
|
PFDN4 |
5203 |
Q9NQP4 |
0.49 |
|
PKN1 |
5585 |
Q16512 |
0.49 |
|
MAPK11 |
5600 |
Q15759 |
0.49 |
|
PTK7 |
5754 |
Q13308 |
0.49 |
|
SARS |
6301 |
P49591 |
0.49 |
|
SRPK1 |
6732 |
Q96SB4 |
0.49 |
|
SRPK2 |
6733 |
P78362 |
0.49 |
|
TPD52L2 |
7165 |
O43399 |
0.49 |
|
HIST3H3 |
8290 |
Q16695 |
0.49 |
|
HIST1H2BC; HIST1H2BE; HIST1H2BF; HIST1H2BG; HIST1H2BI |
8339 |
P62807 |
0.49 |
|
KYNU |
8942 |
Q16719 |
0.49 |
|
IPO8 |
10526 |
O15397 |
0.49 |
|
IPO7 |
10527 |
O95373 |
0.49 |
|
BTRC |
8945 |
Q9Y297 |
0.52 |
|
APEH |
327 |
P13798 |
0.63 |
|
BARD1 |
580 |
Q99728 |
0.63 |
|
ECT2 |
1894 |
Q9H8V3 |
0.63 |
|
H2AFX |
3014 |
P16104 |
0.63 |
|
HSPA4 |
3308 |
P34932 |
0.63 |
|
IFI16 |
3428 |
Q16666 |
0.63 |
|
JUN |
3725 |
P05412 |
0.63 |
|
LRPAP1 |
4043 |
P30533 |
0.63 |
|
NCBP1 |
4686 |
Q09161 |
0.63 |
|
NPM1 |
4869 |
P06748 |
0.63 |
|
NTRK1 |
4914 |
P04629 |
0.63 |
|
PAWR |
5074 |
Q96IZ0 |
0.63 |
|
ABCE1 |
6059 |
P61221 |
0.63 |
|
RPS3A |
6189 |
P61247 |
0.63 |
|
RPS6KA1 |
6195 |
Q15418 |
0.63 |
|
RPS6KB2 |
6199 |
Q9UBS0 |
0.63 |
|
SNRNP70 |
6625 |
P08621 |
0.63 |
|
TP53 |
7157 |
P04637 |
0.63 |
|
TRAF6 |
7189 |
Q9Y4K3 |
0.63 |
|
UGP2 |
7360 |
Q16851 |
0.63 |
|
SPHK1 |
8877 |
Q9NYA1 |
0.63 |
|
POP1 |
10940 |
Q99575 |
0.63 |
|
FAF1 |
11124 |
Q9UNN5 |
0.63 |
|
JMJD6 |
23210 |
Q6NYC1 |
0.63 |
|
SIRT7 |
51547 |
Q9NRC8 |
0.63 |
|
VPS29 |
51699 |
Q9UBQ0 |
0.63 |
|
OTUB1 |
55611 |
Q96FW1 |
0.63 |
|
FBXO38 |
81545 |
Q6PIJ6 |
0.63 |
|
SLX4 |
84464 |
Q8IY92 |
0.63 |
|
HIST1H4A; HIST1H4B; HIST1H4C; HIST1H4D; HIST1H4E; HIST1H4F; HIST1H4H; HIST1H4I; HIST1H4J; HIST1H4K; HIST1H4L; HIST2H4A; HIST2H4B; HIST4H4 |
121504 |
P62805 |
0.63 |
|
PYHIN1 |
149628 |
Q6K0P9 |
0.63 |
|
HIST1H2BA |
255626 |
Q96A08 |
0.63 |
|
MSL1 |
339287 |
Q68DK7 |
0.63 |
|
IRF5 |
3663 |
Q13568 |
0.72 |
|
OAS3 |
4940 |
Q9Y6K5 |
0.72 |
|
RBM4 |
5936 |
Q9BWF3 |
0.72 |
|
TFEB |
7942 |
P19484 |
0.72 |
|
YEATS4 |
8089 |
O95619 |
0.72 |
|
LRIF1 |
55791 |
Q5T3J3 |
0.72 |
|
RBM45 |
129831 |
Q8IUH3 |
0.72 |
|
TERF2 |
7014 |
Q15554 |
0.73 |
|
TERF2IP |
54386 |
Q9NYB0 |
0.73 |
|
SUMO2 |
6613 |
P61956 |
0.74 |
|
MTNR1B |
4544 |
P49286 |
0.75 |
|
TERF1 |
7013 |
P54274 |
0.75 |
|
USP7 |
7874 |
Q93009 |
0.76 |
|
BAP1 |
8314 |
Q92560 |
0.76 |
|
USP49 |
25862 |
Q70CQ1 |
0.76 |
|
USP36 |
57602 |
Q9P275 |
0.76 |