Gene Symbol | SERPINB5 |
Entrez ID | 5268 |
Uniprot ID | P36952 |
Description | serpin peptidase inhibitor, clade B (ovalbumin), member 5 |
Chromosomal Location | chr18: 63,476,761-63,505,085 |
Ontology | GO ID | GO Term | Definition | Evidence |
---|---|---|---|---|
BP |
GO:0002009 |
morphogenesis of an epithelium |
The process in which the anatomical structures of epithelia are generated and organized. An epithelium consists of closely packed cells arranged in one or more layers, that covers the outer surfaces of the body or lines any internal cavity or tube. |
IEA |
BP |
GO:0006928 |
movement of cell or subcellular component |
The directed, self-propelled movement of a cell or subcellular component without the involvement of an external agent such as a transporter or a pore. |
TAS |
BP |
GO:0010951 |
negative regulation of endopeptidase activity |
Any process that decreases the frequency, rate or extent of endopeptidase activity, the endohydrolysis of peptide bonds within proteins. |
IEA |
BP |
GO:0030198 |
extracellular matrix organization |
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an extracellular matrix. |
IEA |
BP |
GO:0050678 |
regulation of epithelial cell proliferation |
Any process that modulates the frequency, rate or extent of epithelial cell proliferation. |
IEA |
BP |
GO:0060512 |
prostate gland morphogenesis |
The process in which the anatomical structures of a prostate gland are generated and organized. |
IEA |
CC |
GO:0005615 |
extracellular space |
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid. |
IBA |
CC |
GO:0005737 |
cytoplasm |
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
IDA |
CC |
GO:0070062 |
extracellular exosome |
A membrane-bounded vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm. |
IDA |
MF |
GO:0004867 |
serine-type endopeptidase inhibitor activity |
Stops, prevents or reduces the activity of serine-type endopeptidases, enzymes that catalyze the hydrolysis of nonterminal peptide bonds in a polypeptide chain; a serine residue (and a histidine residue) are at the active center of the enzyme. |
IBA |
MF |
GO:0005515 |
protein binding |
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules). |
IPI |
Domain ID | Description |
---|---|
IPR000215 |
Serpin family |
IPR000240 |
Serpin B9/maspin |
IPR023795 |
Serpin, conserved site |
IPR023796 |
Serpin domain |
IPR033836 |
Maspin |
Pathway ID | Pathway Term | Pathway Source |
---|---|---|
hsa04115 |
p53 signaling pathway |
KEGG |
hsa05206 |
MicroRNAs in cancer |
KEGG |
UMLS CUI | UMLS Term |
---|---|
C0009375 |
Colonic Neoplasms |
C0009404 |
Colorectal Neoplasms |
C0022548 |
Keloid |
C0027627 |
Neoplasm Metastasis |
C1134719 |
Invasive Ductal Breast Carcinoma |
C1458155 |
Mammary Neoplasms |
Tissue | Cell Type |
---|---|
esophagus |
squamous epithelial cells |
skin |
keratinocytes |
urinary bladder |
urothelial cells |
Pubmed ID | Author | Year | Title |
---|---|---|---|
17148555 |
Wood et al. |
2007 |
Molecular Abnormalities in Oocytes from Women with Polycystic Ovary Syndrome Revealed by Microarray Analysis |
Gene Symbol | Entrez ID | Uniprot ID | Score |
---|---|---|---|
ITPA |
3704 |
Q9BY32 |
0.49 |
TPI1 |
7167 |
P60174 |
0.49 |
PRDX6 |
9588 |
P30041 |
0.49 |
PPIL3 |
53938 |
Q9H2H8 |
0.49 |
AKT1 |
207 |
P31749 |
0.63 |
ALDH2 |
217 |
P05091 |
0.63 |
RHOA |
387 |
P61586 |
0.63 |
CBFB |
865 |
Q13951 |
0.63 |
HDLBP |
3069 |
Q00341 |
0.63 |
HMGCS1 |
3157 |
Q01581 |
0.63 |
SMAD4 |
4089 |
Q13485 |
0.63 |
NARS |
4677 |
O43776 |
0.63 |
PLS1 |
5357 |
Q14651 |
0.63 |
STK11 |
6794 |
Q15831 |
0.63 |
VRK1 |
7443 |
Q99986 |
0.63 |
XRCC3 |
7517 |
O43542 |
0.63 |
EIF2S2 |
8894 |
P20042 |
0.63 |
ZRANB2 |
9406 |
O95218 |
0.63 |
ZC3H11A |
9877 |
O75152 |
0.63 |
DDX46 |
9879 |
Q7L014 |
0.63 |
SF3A1 |
10291 |
Q15459 |
0.63 |
UBA6 |
55236 |
A0AVT1 |
0.63 |
NAA50 |
80218 |
Q9GZZ1 |
0.63 |
EIF2A |
83939 |
Q9BY44 |
0.63 |
HDGFRP2 |
84717 |
Q7Z4V5 |
0.63 |
RAP1BL |
643752 |
A6NIZ1 |
0.63 |
KHDRBS3 |
10656 |
O75525 |
0.72 |
FBXO32 |
114907 |
Q969P5 |
0.72 |
ADA |
100 |
P00813 |
0.49 |
SOD1 |
6647 |
P00441 |
0.49 |
C11orf54 |
28970 |
Q9H0W9 |
0.49 |
GLOD4 |
51031 |
Q9HC38 |
0.49 |
UCHL5 |
51377 |
Q9Y5K5 |
0.56 |
CASP8 |
841 |
Q14790 |
0.63 |
ESR1 |
2099 |
P03372 |
0.63 |
GPR18 |
2841 |
Q14330 |
0.63 |
KIR3DS1 |
3813 |
Q14943 |
0.63 |
KRAS |
3845 |
P01116 |
0.63 |
MAPK9 |
5601 |
P45984 |
0.63 |
SUMO2 |
6613 |
P61956 |
0.63 |
BCAR3 |
8412 |
O75815 |
0.63 |
RAB11B |
9230 |
Q15907 |
0.63 |
ISG15 |
9636 |
P05161 |
0.63 |
DDX19B |
11269 |
Q9UMR2 |
0.63 |
RAB9B |
51209 |
Q9NP90 |
0.63 |
WWOX |
51741 |
Q9NZC7 |
0.63 |
UGT1A10 |
54575 |
Q9HAW8 |
0.63 |
PALB2 |
79728 |
Q86YC2 |
0.63 |
SLX4 |
84464 |
Q8IY92 |
0.63 |
LACC1 |
144811 |
Q8IV20 |
0.63 |
PYHIN1 |
149628 |
Q6K0P9 |
0.63 |
SGO2 |
151246 |
Q562F6 |
0.63 |
RBM24 |
221662 |
Q9BX46 |
0.63 |
HDAC1 |
3065 |
Q13547 |
0.68 |
PRSS21 |
10942 |
Q9Y6M0 |
0.78 |