| Gene Symbol | PGM1 |
| Entrez ID | 5236 |
| Uniprot ID | P36871 |
| Description | phosphoglucomutase 1 |
| Chromosomal Location | chr1: 63,593,276-63,660,245 |
| Ontology | GO ID | GO Term | Definition | Evidence |
|---|---|---|---|---|
|
BP |
GO:0005978 |
glycogen biosynthetic process |
The chemical reactions and pathways resulting in the formation of glycogen, a polydisperse, highly branched glucan composed of chains of D-glucose residues. |
IBA|TAS |
|
BP |
GO:0005980 |
glycogen catabolic process |
The chemical reactions and pathways resulting in the breakdown of glycogen, a polydisperse, highly branched glucan composed of chains of D-glucose residues. |
TAS |
|
BP |
GO:0006006 |
glucose metabolic process |
The chemical reactions and pathways involving glucose, the aldohexose gluco-hexose. D-glucose is dextrorotatory and is sometimes known as dextrose; it is an important source of energy for living organisms and is found free as well as combined in homo- and hetero-oligosaccharides and polysaccharides. |
IDA|NAS |
|
BP |
GO:0006094 |
gluconeogenesis |
The formation of glucose from noncarbohydrate precursors, such as pyruvate, amino acids and glycerol. |
TAS |
|
BP |
GO:0006096 |
glycolytic process |
The chemical reactions and pathways resulting in the breakdown of a carbohydrate into pyruvate, with the concomitant production of a small amount of ATP and the reduction of NAD(P) to NAD(P)H. Glycolysis begins with the metabolism of a carbohydrate to generate products that can enter the pathway and ends with the production of pyruvate. Pyruvate may be converted to acetyl-coenzyme A, ethanol, lactate, or other small molecules. |
TAS |
|
BP |
GO:0019388 |
galactose catabolic process |
The chemical reactions and pathways resulting in the breakdown of galactose, the aldohexose galacto-hexose. |
IBA|TAS |
|
CC |
GO:0005737 |
cytoplasm |
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
NAS |
|
CC |
GO:0005829 |
cytosol |
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. |
IBA|TAS |
|
CC |
GO:0015629 |
actin cytoskeleton |
The part of the cytoskeleton (the internal framework of a cell) composed of actin and associated proteins. Includes actin cytoskeleton-associated complexes. |
IDA |
|
CC |
GO:0070062 |
extracellular exosome |
A membrane-bounded vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm. |
IDA |
|
MF |
GO:0000287 |
magnesium ion binding |
Interacting selectively and non-covalently with magnesium (Mg) ions. |
IDA |
|
MF |
GO:0004614 |
phosphoglucomutase activity |
Catalysis of the reaction: alpha-D-glucose 1-phosphate = alpha-D-glucose 6-phosphate. |
EXP|IDA|TAS |
| Domain ID | Description |
|---|---|
|
IPR005841 |
Alpha-D-phosphohexomutase superfamily |
|
IPR005843 |
Alpha-D-phosphohexomutase, C-terminal |
|
IPR005844 |
Alpha-D-phosphohexomutase, alpha/beta/alpha domain I |
|
IPR005845 |
Alpha-D-phosphohexomutase, alpha/beta/alpha domain II |
|
IPR005846 |
Alpha-D-phosphohexomutase, alpha/beta/alpha domain III |
|
IPR016055 |
Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III |
|
IPR016066 |
Alpha-D-phosphohexomutase, conserved site |
| Pathway ID | Pathway Term | Pathway Source |
|---|---|---|
|
hsa00010 |
Glycolysis / Gluconeogenesis |
KEGG |
|
hsa00030 |
Pentose phosphate pathway |
KEGG |
|
hsa00052 |
Galactose metabolism |
KEGG |
|
hsa00230 |
Purine metabolism |
KEGG |
|
hsa00500 |
Starch and sucrose metabolism |
KEGG |
|
hsa00520 |
Amino sugar and nucleotide sugar metabolism |
KEGG |
|
hsa01100 |
Metabolic pathways |
KEGG |
|
WP698 |
Glucuronidation |
WikiPathways |
|
WP2858 |
Ectoderm Differentiation |
WikiPathways |
|
WP500 |
Glycogen Metabolism |
WikiPathways |
| UMLS CUI | UMLS Term |
|---|---|
|
C0011854 |
Diabetes Mellitus, Insulin-Dependent |
|
C0151744 |
Myocardial Ischemia |
| Tissue | Cell Type |
|---|---|
|
liver |
hepatocytes |
| Pubmed ID | Author | Year | Title |
|---|---|---|---|
|
19141577 |
Kim et al. |
2009 |
Transcriptional Profiling with a Pathway-Oriented Analysis Identifies Dysregulated Molecular Phenotypes in the Endometrium of Patients with Polycystic Ovary Syndrome |
| Gene Symbol | Entrez ID | Uniprot ID | Score |
|---|---|---|---|
|
CAT |
847 |
P04040 |
0.49 |
|
ENO1 |
2023 |
P06733 |
0.49 |
|
GALK2 |
2585 |
Q01415 |
0.49 |
|
GPI |
2821 |
P06744 |
0.49 |
|
LTA4H |
4048 |
P09960 |
0.49 |
|
PGM3 |
5238 |
O95394 |
0.49 |
|
TPI1 |
7167 |
P60174 |
0.49 |
|
PRDX6 |
9588 |
P30041 |
0.49 |
|
SCCPDH |
51097 |
Q8NBX0 |
0.49 |
|
EXOC2 |
55770 |
Q96KP1 |
0.49 |
|
APP |
351 |
P05067 |
0.56 |
|
ATIC |
471 |
P31939 |
0.56 |
|
TALDO1 |
6888 |
P37837 |
0.59 |
|
PGM2 |
55276 |
Q96G03 |
0.59 |
|
ENO3 |
2027 |
P13929 |
0.63 |
|
DNAJB6 |
10049 |
O75190 |
0.63 |
|
ABAT |
18 |
P80404 |
0.49 |
|
ALDH2 |
217 |
P05091 |
0.49 |
|
ALDH1B1 |
219 |
P30837 |
0.49 |
|
FAH |
2184 |
P16930 |
0.49 |
|
FH |
2271 |
P07954 |
0.49 |
|
LDHA |
3939 |
P00338 |
0.49 |
|
LDHB |
3945 |
P07195 |
0.49 |
|
SORD |
6652 |
Q00796 |
0.49 |
|
UQCRFS1 |
7386 |
P47985 |
0.49 |
|
FUBP1 |
8880 |
Q96AE4 |
0.49 |
|
GPD1L |
23171 |
Q8N335 |
0.49 |
|
KYAT3 |
56267 |
Q6YP21 |
0.49 |
|
NIT2 |
56954 |
Q9NQR4 |
0.49 |
|
ABHD11 |
83451 |
Q8NFV4 |
0.49 |
|
OAT |
4942 |
P04181 |
0.56 |
|
SOD1 |
6647 |
P00441 |
0.56 |
|
MDH1 |
4190 |
P40925 |
0.59 |
|
GRHPR |
9380 |
Q9UBQ7 |
0.59 |
|
FUS |
2521 |
P35637 |
0.63 |
|
HSPB2 |
3316 |
Q16082 |
0.63 |
|
NTRK1 |
4914 |
P04629 |
0.63 |
|
USP4 |
7375 |
Q13107 |
0.63 |
|
PAXIP1 |
22976 |
Q6ZW49 |
0.63 |
|
KIF1B |
23095 |
O60333 |
0.63 |
|
UBA5 |
79876 |
Q9GZZ9 |
0.72 |
|
TERF1 |
7013 |
P54274 |
0.73 |
|
POT1 |
25913 |
Q9NUX5 |
0.73 |
|
TERF2IP |
54386 |
Q9NYB0 |
0.73 |
|
TINF2 |
26277 |
Q9BSI4 |
0.75 |
|
S100A1 |
6271 |
P23297 |
0.86 |
|
S100B |
6285 |
P04271 |
0.86 |