Protein Description

Gene Symbol PGM1
Entrez ID 5236
Uniprot ID P36871
Description phosphoglucomutase 1
Chromosomal Location chr1: 63,593,276-63,660,245
Ontology GO ID GO Term Definition Evidence

BP

GO:0005978

glycogen biosynthetic process

The chemical reactions and pathways resulting in the formation of glycogen, a polydisperse, highly branched glucan composed of chains of D-glucose residues.

IBA|TAS

BP

GO:0005980

glycogen catabolic process

The chemical reactions and pathways resulting in the breakdown of glycogen, a polydisperse, highly branched glucan composed of chains of D-glucose residues.

TAS

BP

GO:0006006

glucose metabolic process

The chemical reactions and pathways involving glucose, the aldohexose gluco-hexose. D-glucose is dextrorotatory and is sometimes known as dextrose; it is an important source of energy for living organisms and is found free as well as combined in homo- and hetero-oligosaccharides and polysaccharides.

IDA|NAS

BP

GO:0006094

gluconeogenesis

The formation of glucose from noncarbohydrate precursors, such as pyruvate, amino acids and glycerol.

TAS

BP

GO:0006096

glycolytic process

The chemical reactions and pathways resulting in the breakdown of a carbohydrate into pyruvate, with the concomitant production of a small amount of ATP and the reduction of NAD(P) to NAD(P)H. Glycolysis begins with the metabolism of a carbohydrate to generate products that can enter the pathway and ends with the production of pyruvate. Pyruvate may be converted to acetyl-coenzyme A, ethanol, lactate, or other small molecules.

TAS

BP

GO:0019388

galactose catabolic process

The chemical reactions and pathways resulting in the breakdown of galactose, the aldohexose galacto-hexose.

IBA|TAS

CC

GO:0005737

cytoplasm

All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

NAS

CC

GO:0005829

cytosol

The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

IBA|TAS

CC

GO:0015629

actin cytoskeleton

The part of the cytoskeleton (the internal framework of a cell) composed of actin and associated proteins. Includes actin cytoskeleton-associated complexes.

IDA

CC

GO:0070062

extracellular exosome

A membrane-bounded vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.

IDA

MF

GO:0000287

magnesium ion binding

Interacting selectively and non-covalently with magnesium (Mg) ions.

IDA

MF

GO:0004614

phosphoglucomutase activity

Catalysis of the reaction: alpha-D-glucose 1-phosphate = alpha-D-glucose 6-phosphate.

EXP|IDA|TAS

Domain ID Description

IPR005841

Alpha-D-phosphohexomutase superfamily

IPR005843

Alpha-D-phosphohexomutase, C-terminal

IPR005844

Alpha-D-phosphohexomutase, alpha/beta/alpha domain I

IPR005845

Alpha-D-phosphohexomutase, alpha/beta/alpha domain II

IPR005846

Alpha-D-phosphohexomutase, alpha/beta/alpha domain III

IPR016055

Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III

IPR016066

Alpha-D-phosphohexomutase, conserved site

Pathway ID Pathway Term Pathway Source

hsa00010

Glycolysis / Gluconeogenesis

KEGG

hsa00030

Pentose phosphate pathway

KEGG

hsa00052

Galactose metabolism

KEGG

hsa00230

Purine metabolism

KEGG

hsa00500

Starch and sucrose metabolism

KEGG

hsa00520

Amino sugar and nucleotide sugar metabolism

KEGG

hsa01100

Metabolic pathways

KEGG

WP698

Glucuronidation

WikiPathways

WP2858

Ectoderm Differentiation

WikiPathways

WP500

Glycogen Metabolism

WikiPathways

UMLS CUI UMLS Term

C0011854

Diabetes Mellitus, Insulin-Dependent

C0151744

Myocardial Ischemia

Tissue Cell Type

liver

hepatocytes

No databases found.

Pubmed ID Author Year Title

19141577

Kim et al.

2009

Transcriptional Profiling with a Pathway-Oriented Analysis Identifies Dysregulated Molecular Phenotypes in the Endometrium of Patients with Polycystic Ovary Syndrome

Gene Symbol Entrez ID Uniprot ID Score

CAT

847

P04040

0.49

ENO1

2023

P06733

0.49

GALK2

2585

Q01415

0.49

GPI

2821

P06744

0.49

LTA4H

4048

P09960

0.49

PGM3

5238

O95394

0.49

TPI1

7167

P60174

0.49

PRDX6

9588

P30041

0.49

SCCPDH

51097

Q8NBX0

0.49

EXOC2

55770

Q96KP1

0.49

APP

351

P05067

0.56

ATIC

471

P31939

0.56

TALDO1

6888

P37837

0.59

PGM2

55276

Q96G03

0.59

ENO3

2027

P13929

0.63

DNAJB6

10049

O75190

0.63

ABAT

18

P80404

0.49

ALDH2

217

P05091

0.49

ALDH1B1

219

P30837

0.49

FAH

2184

P16930

0.49

FH

2271

P07954

0.49

LDHA

3939

P00338

0.49

LDHB

3945

P07195

0.49

SORD

6652

Q00796

0.49

UQCRFS1

7386

P47985

0.49

FUBP1

8880

Q96AE4

0.49

GPD1L

23171

Q8N335

0.49

KYAT3

56267

Q6YP21

0.49

NIT2

56954

Q9NQR4

0.49

ABHD11

83451

Q8NFV4

0.49

OAT

4942

P04181

0.56

SOD1

6647

P00441

0.56

MDH1

4190

P40925

0.59

GRHPR

9380

Q9UBQ7

0.59

FUS

2521

P35637

0.63

HSPB2

3316

Q16082

0.63

NTRK1

4914

P04629

0.63

USP4

7375

Q13107

0.63

PAXIP1

22976

Q6ZW49

0.63

KIF1B

23095

O60333

0.63

UBA5

79876

Q9GZZ9

0.72

TERF1

7013

P54274

0.73

POT1

25913

Q9NUX5

0.73

TERF2IP

54386

Q9NYB0

0.73

TINF2

26277

Q9BSI4

0.75

S100A1

6271

P23297

0.86

S100B

6285

P04271

0.86