Protein Description

Gene Symbol PAEP
Entrez ID 5047
Uniprot ID P09466
Description progestagen-associated endometrial protein
Chromosomal Location chr9: 135,561,756-135,566,955
Ontology GO ID GO Term Definition Evidence

BP

GO:0006810

transport

The directed movement of substances (such as macromolecules, small molecules, ions) or cellular components (such as complexes and organelles) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter, pore or motor protein.

IEA

BP

GO:0006915

apoptotic process

A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died.

IDA

BP

GO:0007275

multicellular organism development

The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).

TAS

BP

GO:0032725

positive regulation of granulocyte macrophage colony-stimulating factor production

Any process that activates or increases the frequency, rate, or extent of granulocyte macrophage colony-stimulating factor production.

IDA

BP

GO:2000667

positive regulation of interleukin-13 secretion

Any process that activates or increases the frequency, rate or extent of interleukin-13 secretion.

IDA

BP

GO:2000778

positive regulation of interleukin-6 secretion

Any process that activates or increases the frequency, rate or extent of interleukin-6 secretion.

IDA

CC

GO:0005576

extracellular region

The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.

IEA

MF

GO:0005515

protein binding

Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).

IPI

MF

GO:0036094

small molecule binding

Interacting selectively and non-covalently with a small molecule, any low molecular weight, monomeric, non-encoded molecule.

IEA

Domain ID Description

IPR000566

Lipocalin/cytosolic fatty-acid binding domain

IPR002345

Lipocalin

IPR002447

Beta-lactoglobulin

IPR012674

Calycin

IPR022272

Lipocalin family conserved site

No pathways found.

UMLS CUI UMLS Term

C0000786

Spontaneous Abortion

C1458155

Mammary Neoplasms

No tissues found.

Database Name

DisGeNET

DGA

No sources found.

Gene Symbol Entrez ID Uniprot ID Score

APP

351

P05067

0.56

SMAD3

4088

P84022

0.59

XRCC6

2547

P12956

0.63

UBE2E1

7324

P51965

0.63

COPS6

10980

Q7L5N1

0.63

RIF1

55183

Q5UIP0

0.63

LRIF1

55791

Q5T3J3

0.63

ESYT2

57488

A0FGR8

0.63

GRAMD3

65983

Q96HH9

0.63

IGSF21

84966

Q96ID5

0.63

DDOST

1650

P39656

0.72

GTF3C2

2976

Q8WUA4

0.72

UBL4A

8266

P11441

0.72

SLC25A12

8604

O75746

0.72

DNAJB5

25822

O75953

0.72

ZFP91

80829

Q96JP5

0.72

A2M

2

P01023

0.76

PTPRC

5788

P08575

0.52

EEF1A1

1915

P68104

0.63

IFI16

3428

Q16666

0.63

BANF1

8815

O75531

0.63