Gene Symbol | NTS |
Entrez ID | 4922 |
Uniprot ID | P30990 |
Description | neurotensin |
Chromosomal Location | chr12: 85,874,295-85,882,992 |
Ontology | GO ID | GO Term | Definition | Evidence |
---|---|---|---|---|
BP |
GO:0007165 |
signal transduction |
The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell. |
NAS |
BP |
GO:0050880 |
regulation of blood vessel size |
Any process that modulates the size of blood vessels. |
IEA |
CC |
GO:0005576 |
extracellular region |
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite. |
TAS |
CC |
GO:0030133 |
transport vesicle |
Any of the vesicles of the constitutive secretory pathway, which carry cargo from the endoplasmic reticulum to the Golgi, between Golgi cisternae, from the Golgi to the ER (retrograde transport) or to destinations within or outside the cell. |
IEA |
CC |
GO:0043679 |
axon terminus |
Terminal inflated portion of the axon, containing the specialized apparatus necessary to release neurotransmitters. The axon terminus is considered to be the whole region of thickening and the terminal button is a specialized region of it. |
IBA |
MF |
GO:0005184 |
neuropeptide hormone activity |
The action characteristic of a neuropeptide hormone, any peptide hormone that acts in the central nervous system. A neuropeptide is any of several types of molecules found in brain tissue, composed of short chains of amino acids; they include endorphins, enkephalins, vasopressin, and others. They are often localized in axon terminals at synapses and are classified as putative neurotransmitters, although some are also hormones. |
IBA |
Domain ID | Description |
---|---|
IPR008055 |
Neurotensin/neuromedin N |
UMLS CUI | UMLS Term |
---|---|
C0007370 |
Catalepsy |
C0026837 |
Muscle Rigidity |
C0424295 |
Hyperactive Behavior |
C0428977 |
Bradycardia |
Pubmed ID | Author | Year | Title |
---|---|---|---|
22617121 |
Ouandaogo et al. |
2012 |
Differences in transcriptomic profiles of human cumulus cells isolated from oocytes at GV, MI and MII stages after in vivo andin vitro oocyte maturation |
22951915 |
Haozi et al. |
2012 |
Altered gene expression profile in cumulus cells of mature MII oocytes from patients with polycystic ovary syndrome |
Gene Symbol | Entrez ID | Uniprot ID | Score |
---|---|---|---|
CPE |
1363 |
P16870 |
0.52 |
ARRB2 |
409 |
P32121 |
0.55 |
NTSR2 |
23620 |
O95665 |
0.65 |
MEP1A |
4224 |
Q16819 |
0.67 |
SORT1 |
6272 |
Q99523 |
0.85 |
NTSR1 |
4923 |
P30989 |
0.89 |
PREP |
5550 |
P48147 |
0.52 |
ACE2 |
59272 |
Q9BYF1 |
0.52 |
NLN |
57486 |
Q9BYT8 |
0.63 |