| Gene Symbol | NFKB1 |
| Entrez ID | 4790 |
| Uniprot ID | P19838 |
| Description | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 |
| Chromosomal Location | chr4: 102,501,329-102,617,302 |
| Ontology | GO ID | GO Term | Definition | Evidence |
|---|---|---|---|---|
|
BP |
GO:0000122 |
negative regulation of transcription from RNA polymerase II promoter |
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription from an RNA polymerase II promoter. |
IC|IGI|IMP |
|
BP |
GO:0002223 |
stimulatory C-type lectin receptor signaling pathway |
Any series of molecular signals generated as a consequence of binding to a C-type lectin receptor capable of cellular activation. |
TAS |
|
BP |
GO:0006366 |
transcription from RNA polymerase II promoter |
The synthesis of RNA from a DNA template by RNA polymerase II, originating at an RNA polymerase II promoter. Includes transcription of messenger RNA (mRNA) and certain small nuclear RNAs (snRNAs). |
TAS |
|
BP |
GO:0006915 |
apoptotic process |
A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died. |
IEA |
|
BP |
GO:0006954 |
inflammatory response |
The immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The process is characterized by local vasodilation, extravasation of plasma into intercellular spaces and accumulation of white blood cells and macrophages. |
TAS |
|
BP |
GO:0007249 |
I-kappaB kinase/NF-kappaB signaling |
The process in which a signal is passed on to downstream components within the cell through the I-kappaB-kinase (IKK)-dependent activation of NF-kappaB. The cascade begins with activation of a trimeric IKK complex (consisting of catalytic kinase subunits IKKalpha and/or IKKbeta, and the regulatory scaffold protein NEMO) and ends with the regulation of transcription of target genes by NF-kappaB. In a resting state, NF-kappaB dimers are bound to I-kappaB proteins, sequestering NF-kappaB in the cytoplasm. Phosphorylation of I-kappaB targets I-kappaB for ubiquitination and proteasomal degradation, thus releasing the NF-kappaB dimers, which can translocate to the nucleus to bind DNA and regulate transcription. |
IBA |
|
BP |
GO:0010629 |
negative regulation of gene expression |
Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form. |
IDA |
|
BP |
GO:0010744 |
positive regulation of macrophage derived foam cell differentiation |
Any process that increases the rate, frequency or extent of macrophage derived foam cell differentiation. Macrophage derived foam cell differentiation is the process in which a macrophage acquires the specialized features of a foam cell. A foam cell is a type of cell containing lipids in small vacuoles and typically seen in atherosclerotic lesions, as well as other conditions. |
IC |
|
BP |
GO:0010884 |
positive regulation of lipid storage |
Any process that increases the rate, frequency or extent of lipid storage. Lipid storage is the accumulation and maintenance in cells or tissues of lipids, compounds soluble in organic solvents but insoluble or sparingly soluble in aqueous solvents. Lipid reserves can be accumulated during early developmental stages for mobilization and utilization at later stages of development. |
IC |
|
BP |
GO:0010956 |
negative regulation of calcidiol 1-monooxygenase activity |
Any process that decreases the rate, frequency or extent of calcidiol 1-monooxygenase activity. Calcidiol 1-monooxygenase activity is the catalysis of the reaction: calcidiol + NADPH + H+ + O2 = calcitriol + NADP+ + H2O. |
IDA |
|
BP |
GO:0010957 |
negative regulation of vitamin D biosynthetic process |
Any process that decreases the rate, frequency or extent of a vitamin D biosynthetic process. Vitamin D biosynthesis is the chemical reactions and pathways resulting in the formation of vitamin D, any of a group of related, fat-soluble compounds that are derived from delta-5,7 steroids and play a central role in calcium metabolism. Specific forms of vitamin D include calciferol (ergocalciferol; vitamin D2) and cholecalciferol (calciol; vitamin D3). |
IC |
|
BP |
GO:0031293 |
membrane protein intracellular domain proteolysis |
The proteolytic cleavage of a transmembrane protein leading to the release of an intracellular domain. |
TAS |
|
BP |
GO:0032269 |
negative regulation of cellular protein metabolic process |
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving a protein, occurring at the level of an individual cell. |
IC |
|
BP |
GO:0032375 |
negative regulation of cholesterol transport |
Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of cholesterol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. |
IC |
|
BP |
GO:0032481 |
positive regulation of type I interferon production |
Any process that activates or increases the frequency, rate, or extent of type I interferon production. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families. |
TAS |
|
BP |
GO:0035994 |
response to muscle stretch |
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a myofibril being extended beyond its slack length. |
IEA |
|
BP |
GO:0038061 |
NIK/NF-kappaB signaling |
The process in which a signal is passed on to downstream components within the cell through the NIK-dependent processing and activation of NF-KappaB. Begins with activation of the NF-KappaB-inducing kinase (NIK), which in turn phosphorylates and activates IkappaB kinase alpha (IKKalpha). IKKalpha phosphorylates the NF-Kappa B2 protein (p100) leading to p100 processing and release of an active NF-KappaB (p52). |
IBA |
|
BP |
GO:0038095 |
Fc-epsilon receptor signaling pathway |
A series of molecular signals initiated by the binding of the Fc portion of immunoglobulin E (IgE) to an Fc-epsilon receptor on the surface of a signal-receiving cell, and ending with regulation of a downstream cellular process, e.g. transcription. The Fc portion of an immunoglobulin is its C-terminal constant region. |
TAS |
|
BP |
GO:0043066 |
negative regulation of apoptotic process |
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process. |
TAS |
|
BP |
GO:0045083 |
negative regulation of interleukin-12 biosynthetic process |
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-12. |
IEA |
|
BP |
GO:0045087 |
innate immune response |
Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens. |
IBA |
|
BP |
GO:0045893 |
positive regulation of transcription, DNA-templated |
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription. |
IDA|IMP|NAS |
|
BP |
GO:0045944 |
positive regulation of transcription from RNA polymerase II promoter |
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter. |
IDA|IMP |
|
BP |
GO:0050728 |
negative regulation of inflammatory response |
Any process that stops, prevents, or reduces the frequency, rate or extent of the inflammatory response. |
IEA |
|
BP |
GO:0050852 |
T cell receptor signaling pathway |
A series of molecular signals initiated by the cross-linking of an antigen receptor on a T cell. |
TAS |
|
BP |
GO:0051092 |
positive regulation of NF-kappaB transcription factor activity |
Any process that activates or increases the frequency, rate or extent of activity of the transcription factor NF-kappaB. |
TAS |
|
BP |
GO:0051403 |
stress-activated MAPK cascade |
A series of molecular signals in which a stress-activated MAP kinase cascade relays one or more of the signals; MAP kinase cascades involve at least three protein kinase activities and culminate in the phosphorylation and activation of a MAP kinase. |
TAS |
|
BP |
GO:0071222 |
cellular response to lipopolysaccharide |
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipopolysaccharide stimulus; lipopolysaccharide is a major component of the cell wall of gram-negative bacteria. |
IMP |
|
BP |
GO:0071260 |
cellular response to mechanical stimulus |
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mechanical stimulus. |
IEP |
|
BP |
GO:0071316 |
cellular response to nicotine |
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nicotine stimulus. |
IMP |
|
BP |
GO:0071347 |
cellular response to interleukin-1 |
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-1 stimulus. |
IEP |
|
BP |
GO:0071354 |
cellular response to interleukin-6 |
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-6 stimulus. |
IMP |
|
BP |
GO:0071359 |
cellular response to dsRNA |
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a double-stranded RNA stimulus. |
IEA |
|
BP |
GO:0071375 |
cellular response to peptide hormone stimulus |
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide hormone stimulus. A peptide hormone is any of a class of peptides that are secreted into the blood stream and have endocrine functions in living animals. |
IMP |
|
BP |
GO:0090263 |
positive regulation of canonical Wnt signaling pathway |
Any process that increases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin, the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes. |
IMP |
|
BP |
GO:1900127 |
positive regulation of hyaluronan biosynthetic process |
Any process that activates or increases the frequency, rate or extent of hyaluronan biosynthetic process. |
IDA |
|
BP |
GO:2000630 |
positive regulation of miRNA metabolic process |
Any process that activates or increases the frequency, rate or extent of miRNA metabolic process. |
IMP |
|
CC |
GO:0005634 |
nucleus |
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
IDA |
|
CC |
GO:0005654 |
nucleoplasm |
That part of the nuclear content other than the chromosomes or the nucleolus. |
IDA|TAS |
|
CC |
GO:0005737 |
cytoplasm |
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
IDA |
|
CC |
GO:0005739 |
mitochondrion |
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration. |
IDA |
|
CC |
GO:0005829 |
cytosol |
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. |
IBA|TAS |
|
CC |
GO:0033256 |
I-kappaB/NF-kappaB complex |
A protein complex containing an inhibitory-kappaB (I-kappaB/IKB) protein and one or more copies of an NF-kappaB protein. In the resting state, NF-kappaB dimers are bound to I-kappaB proteins, sequestering NF-kappaB in the cytoplasm. |
TAS |
|
MF |
GO:0000975 |
regulatory region DNA binding |
Interacting selectively and non-covalently with a DNA region that regulates a DNA-based process. Such processes include transcription, DNA replication, and DNA repair. |
IDA |
|
MF |
GO:0000976 |
transcription regulatory region sequence-specific DNA binding |
Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls transcription of that section of the DNA. The transcribed region might be described as a gene, cistron, or operon. |
IDA |
|
MF |
GO:0000977 |
RNA polymerase II regulatory region sequence-specific DNA binding |
Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls the transcription of a gene or cistron by RNA polymerase II. |
IDA |
|
MF |
GO:0000980 |
RNA polymerase II distal enhancer sequence-specific DNA binding |
Interacting selectively and non-covalently with a RNA polymerase II (Pol II) distal enhancer. In mammalian cells, enhancers are distal sequences that increase the utilization of some promoters, and can function in either orientation and in any location (upstream or downstream) relative to the core promoter. |
IDA |
|
MF |
GO:0001205 |
transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding |
Interacting selectively and non-covalently with a sequence of DNA that is in a distal enhancer region for RNA polymerase II (RNAP II) in order to activate or increase the frequency, rate or extent of transcription from the RNAP II promoter. |
IDA |
|
MF |
GO:0001227 |
transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding |
Interacting selectively and non-covalently with a sequence of DNA that is in the regulatory region for RNA polymerase II (RNAP II) in order to stop, prevent, or reduce the frequency, rate or extent of transcription from an RNA polymerase II promoter. |
IDA |
|
MF |
GO:0003682 |
chromatin binding |
Interacting selectively and non-covalently with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase. |
IBA |
|
MF |
GO:0003700 |
transcription factor activity, sequence-specific DNA binding |
Interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription. The transcription factor may or may not also interact selectively with a protein or macromolecular complex. |
IDA |
|
MF |
GO:0005515 |
protein binding |
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules). |
IPI |
|
MF |
GO:0008134 |
transcription factor binding |
Interacting selectively and non-covalently with a transcription factor, any protein required to initiate or regulate transcription. |
IDA |
|
MF |
GO:0042802 |
identical protein binding |
Interacting selectively and non-covalently with an identical protein or proteins. |
IPI |
|
MF |
GO:0042803 |
protein homodimerization activity |
Interacting selectively and non-covalently with an identical protein to form a homodimer. |
IEA |
|
MF |
GO:0042805 |
actinin binding |
Interacting selectively and non-covalently with actinin, any member of a family of proteins that crosslink F-actin. |
IPI |
|
MF |
GO:0044212 |
transcription regulatory region DNA binding |
Interacting selectively and non-covalently with a DNA region that regulates the transcription of a region of DNA, which may be a gene, cistron, or operon. Binding may occur as a sequence specific interaction or as an interaction observed only once a factor has been recruited to the DNA by other factors. |
IDA |
|
MF |
GO:0046982 |
protein heterodimerization activity |
Interacting selectively and non-covalently with a nonidentical protein to form a heterodimer. |
IDA |
| Domain ID | Description |
|---|---|
|
IPR000451 |
NF-kappa-B/Dorsal |
|
IPR000488 |
Death domain |
|
IPR002110 |
Ankyrin repeat |
|
IPR002909 |
IPT domain |
|
IPR008967 |
p53-like transcription factor, DNA-binding |
|
IPR011029 |
Death-like domain |
|
IPR011539 |
Rel homology domain (RHD), DNA-binding domain |
|
IPR013783 |
Immunoglobulin-like fold |
|
IPR014756 |
Immunoglobulin E-set |
|
IPR020683 |
Ankyrin repeat-containing domain |
|
IPR030492 |
Rel homology domain, conserved site |
|
IPR030503 |
Nuclear factor NF-kappa-B, p105 subunit |
|
IPR032397 |
Rel homology dimerisation domain |
|
IPR033926 |
NFkappaB IPT domain |
| Pathway ID | Pathway Term | Pathway Source |
|---|---|---|
|
hsa01523 |
Antifolate resistance |
KEGG |
|
hsa04010 |
MAPK signaling pathway |
KEGG |
|
hsa04014 |
Ras signaling pathway |
KEGG |
|
hsa04024 |
cAMP signaling pathway |
KEGG |
|
hsa04062 |
Chemokine signaling pathway |
KEGG |
|
hsa04064 |
NF-kappa B signaling pathway |
KEGG |
|
hsa04066 |
HIF-1 signaling pathway |
KEGG |
|
hsa04071 |
Sphingolipid signaling pathway |
KEGG |
|
hsa04151 |
PI3K-Akt signaling pathway |
KEGG |
|
hsa04210 |
Apoptosis |
KEGG |
|
hsa04211 |
Longevity regulating pathway |
KEGG |
|
hsa04380 |
Osteoclast differentiation |
KEGG |
|
hsa04620 |
Toll-like receptor signaling pathway |
KEGG |
|
hsa04621 |
NOD-like receptor signaling pathway |
KEGG |
|
hsa04622 |
RIG-I-like receptor signaling pathway |
KEGG |
|
hsa04623 |
Cytosolic DNA-sensing pathway |
KEGG |
|
hsa04657 |
IL-17 signaling pathway |
KEGG |
|
hsa04658 |
Th1 and Th2 cell differentiation |
KEGG |
|
hsa04659 |
Th17 cell differentiation |
KEGG |
|
hsa04660 |
T cell receptor signaling pathway |
KEGG |
|
hsa04662 |
B cell receptor signaling pathway |
KEGG |
|
hsa04668 |
TNF signaling pathway |
KEGG |
|
hsa04722 |
Neurotrophin signaling pathway |
KEGG |
|
hsa04917 |
Prolactin signaling pathway |
KEGG |
|
hsa04920 |
Adipocytokine signaling pathway |
KEGG |
|
hsa04931 |
Insulin resistance |
KEGG |
|
hsa04932 |
Non-alcoholic fatty liver disease (NAFLD) |
KEGG |
|
hsa04933 |
AGE-RAGE signaling pathway in diabetic complications |
KEGG |
|
hsa05030 |
Cocaine addiction |
KEGG |
|
hsa05120 |
Epithelial cell signaling in Helicobacter pylori infection |
KEGG |
|
hsa05131 |
Shigellosis |
KEGG |
|
hsa05132 |
Salmonella infection |
KEGG |
|
hsa05133 |
Pertussis |
KEGG |
|
hsa05134 |
Legionellosis |
KEGG |
|
hsa05140 |
Leishmaniasis |
KEGG |
|
hsa05142 |
Chagas disease (American trypanosomiasis) |
KEGG |
|
hsa05145 |
Toxoplasmosis |
KEGG |
|
hsa05146 |
Amoebiasis |
KEGG |
|
hsa05152 |
Tuberculosis |
KEGG |
|
hsa05160 |
Hepatitis C |
KEGG |
|
hsa05161 |
Hepatitis B |
KEGG |
|
hsa05162 |
Measles |
KEGG |
|
hsa05164 |
Influenza A |
KEGG |
|
hsa05166 |
HTLV-I infection |
KEGG |
|
hsa05168 |
Herpes simplex infection |
KEGG |
|
hsa05169 |
Epstein-Barr virus infection |
KEGG |
|
hsa05200 |
Pathways in cancer |
KEGG |
|
hsa05202 |
Transcriptional misregulation in cancer |
KEGG |
|
hsa05203 |
Viral carcinogenesis |
KEGG |
|
hsa05206 |
MicroRNAs in cancer |
KEGG |
|
hsa05212 |
Pancreatic cancer |
KEGG |
|
hsa05215 |
Prostate cancer |
KEGG |
|
hsa05220 |
Chronic myeloid leukemia |
KEGG |
|
hsa05221 |
Acute myeloid leukemia |
KEGG |
|
hsa05222 |
Small cell lung cancer |
KEGG |
|
hsa05321 |
Inflammatory bowel disease (IBD) |
KEGG |
|
hsa05418 |
Fluid shear stress and atherosclerosis |
KEGG |
|
WP23 |
B Cell Receptor Signaling Pathway |
WikiPathways |
|
WP1533 |
Vitamin B12 Metabolism |
WikiPathways |
|
WP3941 |
Oxidative Damage |
WikiPathways |
|
WP195 |
IL-1 signaling pathway |
WikiPathways |
|
WP560 |
TGF-beta Receptor Signaling |
WikiPathways |
|
WP1984 |
Integrated Breast Cancer Pathway |
WikiPathways |
|
WP706 |
Sudden Infant Death Syndrome (SIDS) Susceptibility Pathways |
WikiPathways |
|
WP15 |
Selenium Micronutrient Network |
WikiPathways |
|
WP2865 |
IL1 and megakaryocytes in obesity |
WikiPathways |
|
WP3929 |
Chemokine signaling pathway |
WikiPathways |
|
WP262 |
EBV LMP1 signaling |
WikiPathways |
|
WP3646 |
Hepatitis C and Hepatocellular Carcinoma |
WikiPathways |
|
WP3298 |
Melatonin metabolism and effects |
WikiPathways |
|
WP2324 |
AGE/RAGE pathway |
WikiPathways |
|
WP3863 |
T-Cell antigen Receptor (TCR) pathway during Staphylococcus aureus infection |
WikiPathways |
|
WP1559 |
TFs Regulate miRNAs related to cardiac hypertrophy |
WikiPathways |
|
WP75 |
Toll-like Receptor Signaling Pathway |
WikiPathways |
|
WP3630 |
NAD metabolism, sirtuins and aging |
WikiPathways |
|
WP2355 |
Corticotropin-releasing hormone signaling pathway |
WikiPathways |
|
WP2064 |
Neural Crest Differentiation |
WikiPathways |
|
WP384 |
Apoptosis Modulation by HSP70 |
WikiPathways |
|
WP2036 |
TNF related weak inducer of apoptosis (TWEAK) Signaling Pathway |
WikiPathways |
|
WP3303 |
Rac1/Pak1/p38/MMP-2 pathway |
WikiPathways |
|
WP289 |
Myometrial Relaxation and Contraction Pathways |
WikiPathways |
|
WP3877 |
Simplified Depiction of MYD88 Distinct Input-Output Pathway |
WikiPathways |
|
WP2034 |
Leptin signaling pathway |
WikiPathways |
|
WP710 |
DNA Damage Response (only ATM dependent) |
WikiPathways |
|
WP3878 |
ATM Signaling Network in Development and Disease |
WikiPathways |
|
WP3414 |
Initiation of transcription and translation elongation at the HIV-1 LTR |
WikiPathways |
|
WP3617 |
Photodynamic therapy-induced NF-kB survival signaling |
WikiPathways |
|
WP2435 |
Quercetin and Nf-kB/ AP-1 Induced Cell Apoptosis |
WikiPathways |
|
WP61 |
Notch Signaling Pathway |
WikiPathways |
|
WP2637 |
Structural Pathway of Interleukin 1 (IL-1) |
WikiPathways |
|
WP3849 |
MAPK and NFkB Signalling Pathways Inhibited by Yersinia YopJ |
WikiPathways |
|
WP28 |
Selenium Metabolism and Selenoproteins |
WikiPathways |
|
WP1449 |
Regulation of toll-like receptor signaling pathway |
WikiPathways |
|
WP2112 |
IL17 signaling pathway |
WikiPathways |
|
WP3851 |
TLR4 Signaling and Tolerance |
WikiPathways |
|
WP2374 |
Oncostatin M Signaling Pathway |
WikiPathways |
|
WP3850 |
Factors and pathways affecting insulin-like growth factor (IGF1)-Akt signaling |
WikiPathways |
|
WP3858 |
Toll-like Receptor Signaling |
WikiPathways |
|
WP3865 |
RIG-I-like Receptor Signaling |
WikiPathways |
|
WP382 |
MAPK Signaling Pathway |
WikiPathways |
|
WP2037 |
Prolactin Signaling Pathway |
WikiPathways |
|
WP1434 |
Osteopontin Signaling |
WikiPathways |
|
WP176 |
Folate Metabolism |
WikiPathways |
|
WP1544 |
MicroRNAs in cardiomyocyte hypertrophy |
WikiPathways |
|
WP2583 |
T-Cell Receptor and Co-stimulatory Signaling |
WikiPathways |
|
WP408 |
Oxidative Stress |
WikiPathways |
|
WP254 |
Apoptosis |
WikiPathways |
|
WP2586 |
Aryl Hydrocarbon Receptor |
WikiPathways |
|
WP231 |
TNF alpha Signaling Pathway |
WikiPathways |
|
WP1772 |
Apoptosis Modulation and Signaling |
WikiPathways |
|
WP2018 |
RANKL/RANK (Receptor activator of NFKB (ligand)) Signaling Pathway |
WikiPathways |
|
WP712 |
Estrogen signaling pathway |
WikiPathways |
|
WP2795 |
Cardiac Hypertrophic Response |
WikiPathways |
|
WP2864 |
Apoptosis-related network due to altered Notch3 in ovarian cancer |
WikiPathways |
|
WP2380 |
Brain-Derived Neurotrophic Factor (BDNF) signaling pathway |
WikiPathways |
|
WP395 |
IL-4 Signaling Pathway |
WikiPathways |
|
WP69 |
T-Cell antigen Receptor (TCR) Signaling Pathway |
WikiPathways |
|
WP3888 |
VEGFA-VEGFR2 Signaling Pathway |
WikiPathways |
|
h_RELAPathway |
Acetylation and Deacetylation of RelA in The Nucleus |
BioCarta |
|
h_pkcPathway |
Activation of PKC through G protein coupled receptor |
BioCarta |
|
h_aktPathway |
AKT Signaling Pathway |
BioCarta |
|
h_atmPathway |
ATM Signaling Pathway |
BioCarta |
|
h_ranklPathway |
Bone Remodelling |
BioCarta |
|
h_cdMacPathway |
Cadmium induces DNA synthesis and proliferation in macrophages |
BioCarta |
|
h_cd40Pathway |
CD40L Signaling Pathway |
BioCarta |
|
h_ceramidePathway |
Ceramide Signaling Pathway |
BioCarta |
|
h_tidPathway |
Chaperones modulate interferon Signaling Pathway |
BioCarta |
|
h_gcrPathway |
Corticosteroids and cardioprotection |
BioCarta |
|
h_cxcr4Pathway |
CXCR4 Signaling Pathway |
BioCarta |
|
h_rnaPathway |
Double Stranded RNA Induced Gene Expression |
BioCarta |
|
h_eponfkbPathway |
Erythropoietin mediated neuroprotection through NF-kB |
BioCarta |
|
h_fMLPpathway |
fMLP induced chemokine gene expression in HMC-1 cells |
BioCarta |
|
h_freePathway |
Free Radical Induced Apoptosis |
BioCarta |
|
h_HivnefPathway |
HIV-I Nef: negative effector of Fas and TNF |
BioCarta |
|
h_hcmvPathway |
Human Cytomegalovirus and Map Kinase Pathways |
BioCarta |
|
h_gsk3Pathway |
Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages |
BioCarta |
|
h_deathPathway |
Induction of apoptosis through DR3 and DR4/5 Death Receptors |
BioCarta |
|
h_RacCycDPathway |
Influence of Ras and Rho proteins on G1 to S Transition |
BioCarta |
|
h_keratinocytePathway |
Keratinocyte Differentiation |
BioCarta |
|
h_mapkPathway |
MAPKinase Signaling Pathway |
BioCarta |
|
h_vipPathway |
Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells |
BioCarta |
|
h_nthiPathway |
NFkB activation by Nontypeable Hemophilus influenzae |
BioCarta |
|
h_nfkbPathway |
NF-kB Signaling Pathway |
BioCarta |
|
h_rasPathway |
Ras Signaling Pathway |
BioCarta |
|
h_cardiacegfPathway |
Role of EGF Receptor Transactivation by GPCRs in Cardiac Hypertrophy |
BioCarta |
|
h_il1rPathway |
Signal transduction through IL1R |
BioCarta |
|
h_tcrPathway |
T Cell Receptor Signaling Pathway |
BioCarta |
|
h_tall1Pathway |
TACI and BCMA stimulation of B cell immune responses |
BioCarta |
|
h_41bbPathway |
The 4-1BB-dependent immune response |
BioCarta |
|
h_pcafpathway |
The information-processing pathway at the IFN-beta enhancer |
BioCarta |
|
h_stressPathway |
TNF/Stress Related Signaling |
BioCarta |
|
h_tnfr2Pathway |
TNFR2 Signaling Pathway |
BioCarta |
|
h_tollPathway |
Toll-Like Receptor Pathway |
BioCarta |
| UMLS CUI | UMLS Term |
|---|---|
|
C0001418 |
Adenocarcinoma |
|
C0007621 |
Neoplastic Cell Transformation |
|
C0007786 |
Brain Ischemia |
|
C0009324 |
Ulcerative Colitis |
|
C0009375 |
Colonic Neoplasms |
|
C0009447 |
Common Variable Immunodeficiency |
|
C0011860 |
Diabetes Mellitus, Non-Insulin-Dependent |
|
C0018843 |
Heat Stroke |
|
C0020500 |
Hyperoxaluria |
|
C0022661 |
Kidney Failure, Chronic |
|
C0023892 |
Biliary Cirrhosis |
|
C0023895 |
Liver Diseases |
|
C0029927 |
Ovarian Cysts |
|
C0036341 |
Schizophrenia |
| Tissue | Cell Type |
|---|---|
|
bone marrow |
hematopoietic cells |
|
lymph node |
germinal center cells |
|
lymph node |
non-germinal center cells |
|
tonsil |
germinal center cells |
|
tonsil |
non-germinal center cells |
|
urinary bladder |
urothelial cells |
| Pubmed ID | Author | Year | Title |
|---|---|---|---|
|
22617121 |
Ouandaogo et al. |
2012 |
Differences in transcriptomic profiles of human cumulus cells isolated from oocytes at GV, MI and MII stages after in vivo andin vitro oocyte maturation |
|
22951915 |
Haozi et al. |
2012 |
Altered gene expression profile in cumulus cells of mature MII oocytes from patients with polycystic ovary syndrome |
| Gene Symbol | Entrez ID | Uniprot ID | Score |
|---|---|---|---|
|
RBPJ |
3516 |
Q06330 |
0.00 |
|
PIK3CA |
5290 |
P42336 |
0.00 |
|
PIK3R1 |
5295 |
P27986 |
0.00 |
|
PLD1 |
5337 |
Q13393 |
0.00 |
|
PRKACG |
5568 |
P22612 |
0.00 |
|
PRKCD |
5580 |
Q05655 |
0.00 |
|
PRKCI |
5584 |
P41743 |
0.00 |
|
PRKCZ |
5590 |
Q05513 |
0.00 |
|
SRC |
6714 |
P12931 |
0.00 |
|
TLR2 |
7097 |
O60603 |
0.00 |
|
TLR3 |
7098 |
O15455 |
0.00 |
|
TLR5 |
7100 |
O60602 |
0.00 |
|
VCAM1 |
7412 |
P19320 |
0.00 |
|
TRADD |
8717 |
Q15628 |
0.00 |
|
RIPK2 |
8767 |
O43353 |
0.00 |
|
TNFRSF10B |
8795 |
O14763 |
0.00 |
|
TNFRSF10A |
8797 |
O00220 |
0.00 |
|
NOD2 |
64127 |
Q9HC29 |
0.00 |
|
APLP2 |
334 |
Q06481 |
0.49 |
|
ATP5J |
522 |
P18859 |
0.49 |
|
ERCC6 |
2074 |
Q03468 |
0.49 |
|
PLS3 |
5358 |
P13797 |
0.49 |
|
SPTAN1 |
6709 |
Q13813 |
0.49 |
|
SPTBN1 |
6711 |
Q01082 |
0.49 |
|
DDX46 |
9879 |
Q7L014 |
0.49 |
|
VPS4A |
27183 |
Q9UN37 |
0.49 |
|
SARAF |
51669 |
Q96BY9 |
0.49 |
|
BIRC3 |
330 |
Q13489 |
0.52 |
|
IRF1 |
3659 |
P10914 |
0.52 |
|
CD82 |
3732 |
P27701 |
0.52 |
|
POLR2A |
5430 |
P24928 |
0.52 |
|
UBE2D3 |
7323 |
P61077 |
0.52 |
|
IL2RA |
3559 |
P01589 |
0.55 |
|
MPP6 |
51678 |
Q9NZW5 |
0.56 |
|
ACACA |
31 |
Q13085 |
0.63 |
|
ACTA2 |
59 |
P62736 |
0.63 |
|
ACTB |
60 |
P60709 |
0.63 |
|
ACTG1 |
71 |
P63261 |
0.63 |
|
ADSL |
158 |
P30566 |
0.63 |
|
ALB |
213 |
P02768 |
0.63 |
|
ALOX12B |
242 |
O75342 |
0.63 |
|
ALPI |
248 |
P09923 |
0.63 |
|
SLC25A4 |
291 |
P12235 |
0.63 |
|
ANXA1 |
301 |
P04083 |
0.63 |
|
ANXA2 |
302 |
P07355 |
0.63 |
|
APRT |
353 |
P07741 |
0.63 |
|
ARF4 |
378 |
P18085 |
0.63 |
|
ATP1A1 |
476 |
P05023 |
0.63 |
|
ATP5A1 |
498 |
P25705 |
0.63 |
|
ATP5B |
506 |
P06576 |
0.63 |
|
ATP5C1 |
509 |
P36542 |
0.63 |
|
AZGP1 |
563 |
P25311 |
0.63 |
|
BLMH |
642 |
Q13867 |
0.63 |
|
BSG |
682 |
P35613 |
0.63 |
|
C1QBP |
708 |
Q07021 |
0.63 |
|
CAD |
790 |
P27708 |
0.63 |
|
CALM2 |
805 |
P62158 |
0.63 |
|
CALM3 |
808 |
P62158 |
0.63 |
|
CAT |
847 |
P04040 |
0.63 |
|
CDK1 |
983 |
P06493 |
0.63 |
|
CDSN |
1041 |
Q15517 |
0.63 |
|
CFL1 |
1072 |
P23528 |
0.63 |
|
CHD3 |
1107 |
Q12873 |
0.63 |
|
CKB |
1152 |
P12277 |
0.63 |
|
CLU |
1191 |
P10909 |
0.63 |
|
CLTC |
1213 |
Q00610 |
0.63 |
|
SLC25A10 |
1468 |
Q9UBX3 |
0.63 |
|
DBT |
1629 |
P11182 |
0.63 |
|
DSP |
1832 |
P15924 |
0.63 |
|
EEF1A1 |
1915 |
P68104 |
0.63 |
|
EEF1A2 |
1917 |
Q05639 |
0.63 |
|
EEF1D |
1936 |
P29692 |
0.63 |
|
EEF1G |
1937 |
P26641 |
0.63 |
|
EIF4A1 |
1973 |
P60842 |
0.63 |
|
ELAVL1 |
1994 |
Q15717 |
0.63 |
|
ENO1 |
2023 |
P06733 |
0.63 |
|
EPHA5 |
2044 |
P54756 |
0.63 |
|
FBL |
2091 |
P22087 |
0.63 |
|
ETFA |
2108 |
P13804 |
0.63 |
|
FARSA |
2193 |
Q9Y285 |
0.63 |
|
FLNB |
2317 |
O75369 |
0.63 |
|
GAPDH |
2597 |
P04406 |
0.63 |
|
GNAS |
2778 |
Q5JWF2 |
0.63 |
|
H1F0 |
3005 |
P07305 |
0.63 |
|
HIST1H1C |
3006 |
P16403 |
0.63 |
|
HIST1H1B |
3009 |
P16401 |
0.63 |
|
HIST1H2BB |
3018 |
P33778 |
0.63 |
|
HIST1H1A |
3024 |
Q02539 |
0.63 |
|
HDAC2 |
3066 |
Q92769 |
0.63 |
|
HK1 |
3098 |
P19367 |
0.63 |
|
HNRNPA2B1 |
3181 |
P22626 |
0.63 |
|
HNRNPF |
3185 |
P52597 |
0.63 |
|
HNRNPH1 |
3187 |
P31943 |
0.63 |
|
HNRNPK |
3190 |
P61978 |
0.63 |
|
HNRNPU |
3192 |
Q00839 |
0.63 |
|
HOXC8 |
3224 |
P31273 |
0.63 |
|
HPRT1 |
3251 |
P00492 |
0.63 |
|
DNAJA1 |
3301 |
P31689 |
0.63 |
|
HSPA2 |
3306 |
P54652 |
0.63 |
|
HSP90AA1 |
3320 |
P07900 |
0.63 |
|
HSP90AB3P |
3327 |
Q58FF7 |
0.63 |
|
HSPD1 |
3329 |
P10809 |
0.63 |
|
IGHA1 |
3493 |
P01876 |
0.63 |
|
JCHAIN |
3512 |
P01591 |
0.63 |
|
IGKC |
3514 |
P01834 |
0.63 |
|
IGLC2 |
3538 |
P0CG05 |
0.63 |
|
IMPDH2 |
3615 |
P12268 |
0.63 |
|
KPNA1 |
3836 |
P52294 |
0.63 |
|
KPNA2 |
3838 |
P52292 |
0.63 |
|
KPNA3 |
3840 |
O00505 |
0.63 |
|
LMNB1 |
4001 |
P20700 |
0.63 |
|
LYZ |
4069 |
P61626 |
0.63 |
|
MCM7 |
4176 |
P33993 |
0.63 |
|
MSH2 |
4436 |
P43246 |
0.63 |
|
MTHFD1 |
4522 |
P11586 |
0.63 |
|
MYH9 |
4627 |
P35579 |
0.63 |
|
MYH10 |
4628 |
P35580 |
0.63 |
|
MYL6 |
4637 |
P60660 |
0.63 |
|
NDUFA10 |
4705 |
O95299 |
0.63 |
|
NPM1 |
4869 |
P06748 |
0.63 |
|
OAT |
4942 |
P04181 |
0.63 |
|
PRDX1 |
5052 |
Q06830 |
0.63 |
|
PC |
5091 |
P11498 |
0.63 |
|
PCBD1 |
5092 |
P61457 |
0.63 |
|
PCBP1 |
5093 |
Q15365 |
0.63 |
|
PCBP2 |
5094 |
Q15366 |
0.63 |
|
PCCA |
5095 |
P05165 |
0.63 |
|
PCCB |
5096 |
P05166 |
0.63 |
|
PCMT1 |
5110 |
P22061 |
0.63 |
|
PDHA1 |
5160 |
P08559 |
0.63 |
|
PDHB |
5162 |
P11177 |
0.63 |
|
PFKP |
5214 |
Q01813 |
0.63 |
|
SLC25A3 |
5250 |
Q00325 |
0.63 |
|
PIP |
5304 |
P12273 |
0.63 |
|
PKM |
5315 |
P14618 |
0.63 |
|
PRPH |
5630 |
P41219 |
0.63 |
|
PRPS1 |
5631 |
P60891 |
0.63 |
|
PRPSAP2 |
5636 |
O60256 |
0.63 |
|
PRSS1 |
5644 |
P07477 |
0.63 |
|
PRSS3 |
5646 |
P35030 |
0.63 |
|
PSMC2 |
5701 |
P35998 |
0.63 |
|
PSMC3 |
5702 |
P17980 |
0.63 |
|
PSMD2 |
5708 |
Q13200 |
0.63 |
|
PTPRF |
5792 |
P10586 |
0.63 |
|
RAN |
5901 |
P62826 |
0.63 |
|
RPL11 |
6135 |
P62913 |
0.63 |
|
RPS3A |
6189 |
P61247 |
0.63 |
|
RPS4X |
6191 |
P62701 |
0.63 |
|
RPS8 |
6202 |
P62241 |
0.63 |
|
RPS10 |
6204 |
P46783 |
0.63 |
|
RPS14 |
6208 |
P62263 |
0.63 |
|
RPS15A |
6210 |
P62244 |
0.63 |
|
RPS16 |
6217 |
P62249 |
0.63 |
|
RPS18 |
6222 |
P62269 |
0.63 |
|
RPS28 |
6234 |
P62857 |
0.63 |
|
SEMG1 |
6406 |
P04279 |
0.63 |
|
SEMG2 |
6407 |
Q02383 |
0.63 |
|
SLC1A5 |
6510 |
Q15758 |
0.63 |
|
SNRPB |
6628 |
P14678 |
0.63 |
|
SPRR1A |
6698 |
P35321 |
0.63 |
|
SSR1 |
6745 |
P43307 |
0.63 |
|
STAT5A |
6776 |
P42229 |
0.63 |
|
TCP1 |
6950 |
P17987 |
0.63 |
|
PRDX2 |
7001 |
P32119 |
0.63 |
|
TFAM |
7019 |
Q00059 |
0.63 |
|
TPR |
7175 |
P12270 |
0.63 |
|
CCT3 |
7203 |
P49368 |
0.63 |
|
DNAJC7 |
7266 |
Q99615 |
0.63 |
|
TUBA4A |
7277 |
P68366 |
0.63 |
|
TUBB2A |
7280 |
Q13885 |
0.63 |
|
TUBG1 |
7283 |
P23258 |
0.63 |
|
TUFM |
7284 |
P49411 |
0.63 |
|
UBA52 |
7311 |
P62987 |
0.63 |
|
UBE2L3 |
7332 |
P68036 |
0.63 |
|
UQCRC2 |
7385 |
P22695 |
0.63 |
|
VARS |
7407 |
P26640 |
0.63 |
|
VCP |
7415 |
P55072 |
0.63 |
|
VTN |
7448 |
P04004 |
0.63 |
|
ZFP36 |
7538 |
P26651 |
0.63 |
|
TUBA1A |
7846 |
Q71U36 |
0.63 |
|
ALDH5A1 |
7915 |
P51649 |
0.63 |
|
HSD17B8 |
7923 |
Q92506 |
0.63 |
|
HIST1H2BC; HIST1H2BE; HIST1H2BF; HIST1H2BG; HIST1H2BI |
8339 |
P62807 |
0.63 |
|
TTF2 |
8458 |
Q9UNY4 |
0.63 |
|
IRS4 |
8471 |
O14654 |
0.63 |
|
SLC25A12 |
8604 |
O75746 |
0.63 |
|
DPM1 |
8813 |
O60762 |
0.63 |
|
DNAJA3 |
9093 |
Q96EY1 |
0.63 |
|
INA |
9118 |
Q16352 |
0.63 |
|
AIFM1 |
9131 |
O95831 |
0.63 |
|
DDX21 |
9188 |
Q9NR30 |
0.63 |
|
VAPB |
9217 |
O95292 |
0.63 |
|
VAPA |
9218 |
Q9P0L0 |
0.63 |
|
NPEPPS |
9520 |
P55786 |
0.63 |
|
BAG2 |
9532 |
O95816 |
0.63 |
|
ISG15 |
9636 |
P05161 |
0.63 |
|
MATR3 |
9782 |
P43243 |
0.63 |
|
CKAP5 |
9793 |
Q14008 |
0.63 |
|
RAD50 |
10111 |
Q92878 |
0.63 |
|
LRPPRC |
10128 |
P42704 |
0.63 |
|
TRAP1 |
10131 |
Q12931 |
0.63 |
|
SLC25A13 |
10165 |
Q9UJS0 |
0.63 |
|
DDX39A |
10212 |
O00148 |
0.63 |
|
MRPS31 |
10240 |
Q92665 |
0.63 |
|
STUB1 |
10273 |
Q9UNE7 |
0.63 |
|
TUBA1B |
10376 |
P68363 |
0.63 |
|
TUBB3 |
10381 |
Q13509 |
0.63 |
|
TUBB4B |
10383 |
P68371 |
0.63 |
|
RACK1 |
10399 |
P63244 |
0.63 |
|
SYNCRIP |
10492 |
O60506 |
0.63 |
|
DDX17 |
10521 |
Q92841 |
0.63 |
|
CCT2 |
10576 |
P78371 |
0.63 |
|
AHSA1 |
10598 |
O95433 |
0.63 |
|
MYL12A |
10627 |
P19105 |
0.63 |
|
RGS14 |
10636 |
O43566 |
0.63 |
|
IGF2BP1 |
10642 |
Q9NZI8 |
0.63 |
|
YWHAQ |
10971 |
P27348 |
0.63 |
|
CEP162 |
22832 |
Q5TB80 |
0.63 |
|
TARDBP |
23435 |
Q13148 |
0.63 |
|
FKBP8 |
23770 |
Q14318 |
0.63 |
|
DHRS7B |
25979 |
Q6IAN0 |
0.63 |
|
RBMXL2 |
27288 |
O75526 |
0.63 |
|
RBMX |
27316 |
P38159 |
0.63 |
|
C18orf8 |
29919 |
Q96DM3 |
0.63 |
|
GMPPA |
29926 |
Q96IJ6 |
0.63 |
|
NSDHL |
50814 |
Q15738 |
0.63 |
|
DIRAS2 |
54769 |
Q96HU8 |
0.63 |
|
NSUN2 |
54888 |
Q08J23 |
0.63 |
|
C4orf27 |
54969 |
Q9NWY4 |
0.63 |
|
RIF1 |
55183 |
Q5UIP0 |
0.63 |
|
ATAD3A |
55210 |
Q9NVI7 |
0.63 |
|
C4orf19 |
55286 |
Q8IY42 |
0.63 |
|
NAGK |
55577 |
Q9UJ70 |
0.63 |
|
MCCC1 |
56922 |
Q96RQ3 |
0.63 |
|
TOMM22 |
56993 |
Q9NS69 |
0.63 |
|
CCAR2 |
57805 |
Q8N163 |
0.63 |
|
MCCC2 |
64087 |
Q9HCC0 |
0.63 |
|
GGCT |
79017 |
O75223 |
0.63 |
|
SLC25A22 |
79751 |
Q9H936 |
0.63 |
|
TUBB1 |
81027 |
Q9H4B7 |
0.63 |
|
SEH1L |
81929 |
Q96EE3 |
0.63 |
|
FRMD8 |
83786 |
Q9BZ67 |
0.63 |
|
SLF1 |
84250 |
Q9BQI6 |
0.63 |
|
TUBB6 |
84617 |
Q9BUF5 |
0.63 |
|
TUBA1C |
84790 |
Q9BQE3 |
0.63 |
|
NAV3 |
89795 |
Q8IVL0 |
0.63 |
|
TIMM50 |
92609 |
Q3ZCQ8 |
0.63 |
|
RPS10P5 |
93144 |
Q9NQ39 |
0.63 |
|
SFXN1 |
94081 |
Q9H9B4 |
0.63 |
|
HIST1H4A; HIST1H4B; HIST1H4C; HIST1H4D; HIST1H4E; HIST1H4F; HIST1H4H; HIST1H4I; HIST1H4J; HIST1H4K; HIST1H4L; HIST2H4A; HIST2H4B; HIST4H4 |
121504 |
P62805 |
0.63 |
|
SCLT1 |
132320 |
Q96NL6 |
0.63 |
|
RBBP8NL |
140893 |
Q8NC74 |
0.63 |
|
A2ML1 |
144568 |
A8K2U0 |
0.63 |
|
ANKRD24 |
170961 |
Q8TF21 |
0.63 |
|
CEP112 |
201134 |
Q8N8E3 |
0.63 |
|
ZBTB9 |
221504 |
Q96C00 |
0.63 |
|
HIST1H2AA |
221613 |
Q96QV6 |
0.63 |
|
STXBP4 |
252983 |
Q6ZWJ1 |
0.63 |
|
HIST1H2BA |
255626 |
Q96A08 |
0.63 |
|
SYPL2 |
284612 |
Q5VXT5 |
0.63 |
|
LRRIQ4 |
344657 |
A6NIV6 |
0.63 |
|
ACTBL2 |
345651 |
Q562R1 |
0.63 |
|
TUBB2B |
347733 |
Q9BVA1 |
0.63 |
|
SBSN |
374897 |
Q6UWP8 |
0.63 |
|
CCDC42B |
387885 |
A6NFT4 |
0.63 |
|
HSP90AB2P |
391634 |
Q58FF8 |
0.63 |
|
ANKHD1 |
404734 |
Q8IWZ3 |
0.63 |
|
POTEKP |
440915 |
Q9BYX7 |
0.63 |
|
TRIM72 |
493829 |
Q6ZMU5 |
0.63 |
|
HIST1H2AB; HIST1H2AE |
3012 |
P04908 |
0.63 |
|
TUBA3C; TUBA3D |
113457 |
Q13748 |
0.63 |
|
BRCA1 |
672 |
P38398 |
0.65 |
|
PML |
5371 |
P29590 |
0.65 |
|
CFLAR |
8837 |
O15519 |
0.65 |
|
HSPA4 |
3308 |
P34932 |
0.68 |
|
PPARG |
5468 |
P37231 |
0.68 |
|
PSMD10 |
5716 |
O75832 |
0.68 |
|
HDAC5 |
10014 |
Q9UQL6 |
0.68 |
|
NONO |
4841 |
Q15233 |
0.70 |
|
SFPQ |
6421 |
P23246 |
0.70 |
|
PDCD11 |
22984 |
Q14690 |
0.70 |
|
SIN3A |
25942 |
Q96ST3 |
0.72 |
|
TBK1 |
29110 |
Q9UHD2 |
0.72 |
|
TNIP3 |
79931 |
Q96KP6 |
0.72 |
|
HMGB1 |
3146 |
P09429 |
0.75 |
|
IRF8 |
3394 |
Q02556 |
0.75 |
|
IRF2 |
3660 |
P14316 |
0.75 |
|
IRF9 |
10379 |
Q00978 |
0.75 |
|
PELP1 |
27043 |
Q8IZL8 |
0.75 |
|
KPNA4 |
3839 |
O00629 |
0.78 |
|
FBXW11 |
23291 |
Q9UKB1 |
0.78 |
|
LYL1 |
4066 |
P12980 |
0.79 |
|
EP300 |
2033 |
Q09472 |
0.81 |
|
SLC25A5 |
292 |
P05141 |
0.82 |
|
SLC25A6 |
293 |
P12236 |
0.82 |
|
HSPA1A |
3303 |
P0DMV8 |
0.82 |
|
HSPA1B |
3304 |
P0DMV9 |
0.82 |
|
HSPA5 |
3309 |
P11021 |
0.82 |
|
HSPA6 |
3310 |
P17066 |
0.82 |
|
HSPA8 |
3312 |
P11142 |
0.82 |
|
HSPA9 |
3313 |
P38646 |
0.82 |
|
HNRNPM |
4670 |
P52272 |
0.82 |
|
PRKDC |
5591 |
P78527 |
0.82 |
|
VIM |
7431 |
P08670 |
0.82 |
|
RUVBL1 |
8607 |
Q9Y265 |
0.82 |
|
TUBB4A |
10382 |
P04350 |
0.82 |
|
TUBB |
203068 |
P07437 |
0.82 |
|
HSPA1L |
3305 |
P34931 |
0.84 |
|
HSP90AB1 |
3326 |
P08238 |
0.84 |
|
HIF1AN |
55662 |
Q9NWT6 |
0.86 |
|
BTRC |
8945 |
Q9Y297 |
0.88 |
|
RUVBL2 |
10856 |
Q9Y230 |
0.88 |
|
CHUK |
1147 |
O15111 |
0.89 |
|
NR3C1 |
2908 |
P04150 |
0.89 |
|
IKBKG |
8517 |
Q9Y6K9 |
0.89 |
|
COPB2 |
9276 |
P35606 |
0.89 |
|
TNIP1 |
10318 |
Q15025 |
0.89 |
|
MEN1 |
4221 |
O00255 |
0.90 |
|
REL |
5966 |
Q04864 |
0.90 |
|
STAT3 |
6774 |
P40763 |
0.90 |
|
NFKBIB |
4793 |
Q15653 |
0.94 |
|
NFKBIE |
4794 |
O00221 |
0.95 |
|
BCL3 |
602 |
P20749 |
0.97 |
|
NFKB2 |
4791 |
Q00653 |
0.97 |
|
NFKBIA |
4792 |
P25963 |
0.97 |
|
RELA |
5970 |
Q04206 |
0.97 |
|
RELB |
5971 |
Q01201 |
0.97 |
|
NFKB1 |
4790 |
P19838 |
0.99 |
|
BIRC2 |
329 |
Q13490 |
0.00 |
|
CASP3 |
836 |
P42574 |
0.00 |
|
CASP8 |
841 |
Q14790 |
0.00 |
|
CD14 |
929 |
P08571 |
0.00 |
|
CD40 |
958 |
P25942 |
0.00 |
|
MAPK14 |
1432 |
Q16539 |
0.00 |
|
CSF2 |
1437 |
P04141 |
0.00 |
|
CSNK1A1 |
1452 |
P48729 |
0.00 |
|
FCER2 |
2208 |
P06734 |
0.00 |
|
GLI2 |
2736 |
P10070 |
0.00 |
|
IL1R1 |
3554 |
P14778 |
0.00 |
|
IL6 |
3569 |
P05231 |
0.00 |
|
CXCL8 |
3576 |
P10145 |
0.00 |
|
IL12A |
3592 |
P29459 |
0.00 |
|
IL12B |
3593 |
P29460 |
0.00 |
|
JAK2 |
3717 |
O60674 |
0.00 |
|
LTBR |
4055 |
P36941 |
0.00 |
|
MAP3K1 |
4214 |
Q13233 |
0.00 |
|
MYC |
4609 |
P01106 |
0.00 |
|
MAP2K1 |
5604 |
Q02750 |
0.00 |
|
CCL3 |
6348 |
P10147 |
0.00 |
|
CCL5 |
6352 |
P13501 |
0.00 |
|
CCL11 |
6356 |
P51671 |
0.00 |
|
MAP3K7 |
6885 |
O43318 |
0.00 |
|
IL1R2 |
7850 |
P27930 |
0.00 |
|
CUL1 |
8454 |
Q13616 |
0.00 |
|
FADD |
8772 |
Q13158 |
0.00 |
|
ARHGEF7 |
8874 |
Q14155 |
0.00 |
|
BCL10 |
8915 |
O95999 |
0.00 |
|
IKBKE |
9641 |
Q14164 |
0.00 |
|
AKT3 |
10000 |
Q9Y243 |
0.00 |
|
MALT1 |
10892 |
Q9UDY8 |
0.00 |
|
IRAK4 |
51135 |
Q9NWZ3 |
0.00 |
|
CARD11 |
84433 |
Q9BXL7 |
0.00 |
|
DST |
667 |
Q03001 |
0.49 |
|
GRB14 |
2888 |
Q14449 |
0.49 |
|
HMGB2 |
3148 |
P26583 |
0.49 |
|
IFNGR1 |
3459 |
P15260 |
0.49 |
|
CARM1 |
10498 |
Q86X55 |
0.49 |
|
TNRC6B |
23112 |
Q9UPQ9 |
0.49 |
|
INTS3 |
65123 |
Q68E01 |
0.49 |
|
C1orf52 |
148423 |
Q8N6N3 |
0.49 |
|
JAKMIP1 |
152789 |
Q96N16 |
0.49 |
|
ATF3 |
467 |
P18847 |
0.52 |
|
FOS |
2353 |
P01100 |
0.52 |
|
UBE2K |
3093 |
P61086 |
0.52 |
|
NFRKB |
4798 |
Q6P4R8 |
0.52 |
|
PRKACA |
5566 |
P17612 |
0.52 |
|
SPI1 |
6688 |
P17947 |
0.52 |
|
RIPK1 |
8737 |
Q13546 |
0.52 |
|
CDK9 |
1025 |
P50750 |
0.55 |
|
TNFSF11 |
8600 |
O14788 |
0.55 |
|
G3BP2 |
9908 |
Q9UN86 |
0.55 |
|
NCF1 |
653361 |
P14598 |
0.55 |
|
HMGA1 |
3159 |
P17096 |
0.56 |
|
SRF |
6722 |
P11831 |
0.56 |
|
COMMD7 |
149951 |
Q86VX2 |
0.56 |
|
SERPINA3 |
12 |
P01011 |
0.63 |
|
ANXA4 |
307 |
P09525 |
0.63 |
|
GLUL |
2752 |
P15104 |
0.63 |
|
NR4A1 |
3164 |
P22736 |
0.63 |
|
NOV |
4856 |
P48745 |
0.63 |
|
PSMA4 |
5685 |
P25789 |
0.63 |
|
SUMO1 |
7341 |
P63165 |
0.63 |
|
XPO1 |
7514 |
O14980 |
0.63 |
|
XRCC4 |
7518 |
Q13426 |
0.63 |
|
YY1 |
7528 |
P25490 |
0.63 |
|
CUL5 |
8065 |
Q93034 |
0.63 |
|
DPF1 |
8193 |
Q92782 |
0.63 |
|
NCOA3 |
8202 |
Q9Y6Q9 |
0.63 |
|
CUL4B |
8450 |
Q13620 |
0.63 |
|
CUL4A |
8451 |
Q13619 |
0.63 |
|
CUL3 |
8452 |
Q13618 |
0.63 |
|
TP63 |
8626 |
Q9H3D4 |
0.63 |
|
SOCS3 |
9021 |
O14543 |
0.63 |
|
RPS6KA5 |
9252 |
O75582 |
0.63 |
|
HDAC4 |
9759 |
P56524 |
0.63 |
|
PPARGC1A |
10891 |
Q9UBK2 |
0.63 |
|
COPS6 |
10980 |
Q7L5N1 |
0.63 |
|
GABARAPL2 |
11345 |
P60520 |
0.63 |
|
SIRT1 |
23411 |
Q96EB6 |
0.63 |
|
BRMS1 |
25855 |
Q9HCU9 |
0.63 |
|
PPME1 |
51400 |
Q9Y570 |
0.63 |
|
DCUN1D1 |
54165 |
Q96GG9 |
0.63 |
|
BANP |
54971 |
Q8N9N5 |
0.63 |
|
PHF10 |
55274 |
Q8WUB8 |
0.63 |
|
MAP1LC3B |
81631 |
Q9GZQ8 |
0.63 |
|
MAP1LC3A |
84557 |
Q9H492 |
0.63 |
|
SPPL2A |
84888 |
Q8TCT8 |
0.63 |
|
AR |
367 |
P10275 |
0.65 |
|
ETS1 |
2113 |
P14921 |
0.65 |
|
NCOR2 |
9612 |
Q9Y618 |
0.65 |
|
RNF123 |
63891 |
Q5XPI4 |
0.65 |
|
KAT5 |
10524 |
Q92993 |
0.67 |
|
SF1 |
7536 |
Q15637 |
0.68 |
|
DPF3 |
8110 |
Q92784 |
0.68 |
|
COMMD3 |
23412 |
Q9UBI1 |
0.68 |
|
COMMD5 |
28991 |
Q9GZQ3 |
0.68 |
|
COMMD9 |
29099 |
Q9P000 |
0.68 |
|
COMMD2 |
51122 |
Q86X83 |
0.68 |
|
ECSIT |
51295 |
Q9BQ95 |
0.68 |
|
COMMD10 |
51397 |
Q9Y6G5 |
0.68 |
|
COMMD4 |
54939 |
Q9H0A8 |
0.68 |
|
COMMD8 |
54951 |
Q9NX08 |
0.68 |
|
COMMD1 |
150684 |
Q8N668 |
0.68 |
|
COMMD6 |
170622 |
Q7Z4G1 |
0.68 |
|
GSK3B |
2932 |
P49841 |
0.69 |
|
TRIP4 |
9325 |
Q15650 |
0.70 |
|
SMAD4 |
4089 |
Q13485 |
0.72 |
|
VPS26A |
9559 |
O75436 |
0.72 |
|
NCOR1 |
9611 |
O75376 |
0.72 |
|
HTT |
3064 |
P42858 |
0.73 |
|
TP53BP1 |
7158 |
Q12888 |
0.73 |
|
MXD3 |
83463 |
Q9BW11 |
0.73 |
|
UNC5CL |
222643 |
Q8IV45 |
0.73 |
|
PPP4C |
5531 |
P60510 |
0.74 |
|
RSF1 |
51773 |
Q96T23 |
0.74 |
|
RXRA |
6256 |
P19793 |
0.75 |
|
HDAC3 |
8841 |
O15379 |
0.75 |
|
NCOA6 |
23054 |
Q14686 |
0.75 |
|
PLD3 |
23646 |
Q8IV08 |
0.75 |
|
NKRF |
55922 |
O15226 |
0.75 |
|
MTPN |
136319 |
P58546 |
0.75 |
|
CEBPB |
1051 |
P17676 |
0.76 |
|
ABCC2 |
1244 |
Q92887 |
0.76 |
|
DPF2 |
5977 |
Q92785 |
0.78 |
|
HMGA2 |
8091 |
P52926 |
0.78 |
|
TAB2 |
23118 |
Q9NYJ8 |
0.78 |
|
TSC22D3 |
1831 |
Q99576 |
0.79 |
|
E2F1 |
1869 |
Q01094 |
0.79 |
|
STAT6 |
6778 |
P42226 |
0.79 |
|
ITGB3BP |
23421 |
Q13352 |
0.79 |
|
ESR1 |
2099 |
P03372 |
0.80 |
|
AURKA |
6790 |
O14965 |
0.82 |
|
COPS5 |
10987 |
Q92905 |
0.82 |
|
KLF5 |
688 |
Q13887 |
0.85 |
|
ELF1 |
1997 |
P32519 |
0.85 |
|
NCOA1 |
8648 |
Q15788 |
0.85 |
|
PARP1 |
142 |
P09874 |
0.87 |
|
CTNNB1 |
1499 |
P35222 |
0.87 |
|
RPS3 |
6188 |
P23396 |
0.87 |
|
ELF3 |
1999 |
P78545 |
0.88 |
|
SP1 |
6667 |
P08047 |
0.88 |
|
TXN |
7295 |
P10599 |
0.88 |
|
SPAG9 |
9043 |
O60271 |
0.88 |
|
IKBKB |
3551 |
O14920 |
0.89 |
|
MAP3K8 |
1326 |
P41279 |
0.90 |
|
NOTCH1 |
4851 |
P46531 |
0.90 |
|
TNIP2 |
79155 |
Q8NFZ5 |
0.90 |
|
NFKBIZ |
64332 |
Q9BYH8 |
0.94 |
|
HDAC1 |
3065 |
Q13547 |
0.97 |