PCOSBase

Protein Description

Gene Symbol	DRG1
Entrez ID	4733
Uniprot ID	Q9Y295
Description	developmentally regulated GTP binding protein 1
Chromosomal Location	chr22: 31,399,523-31,530,634

Ontology	GO ID	GO Term	Definition	Evidence
BP	GO:0006351	transcription, DNA-templated	The cellular synthesis of RNA on a template of DNA.	TAS
BP	GO:0007275	multicellular organism development	The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).	TAS
CC	GO:0005737	cytoplasm	All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.	IEA
CC	GO:0005844	polysome	A multiribosomal structure representing a linear array of ribosomes held together by messenger RNA. They represent the active complexes in cellular protein synthesis and are able to incorporate amino acids into polypeptides both in vivo and in vitro.	IDA
CC	GO:0016020	membrane	A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.	IDA
MF	GO:0005515	protein binding	Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).	IPI
MF	GO:0005525	GTP binding	Interacting selectively and non-covalently with GTP, guanosine triphosphate.	IEA
MF	GO:0008134	transcription factor binding	Interacting selectively and non-covalently with a transcription factor, any protein required to initiate or regulate transcription.	TAS

Domain ID	Description
IPR004095	TGS
IPR005225	Small GTP-binding protein domain
IPR006073	GTP binding domain
IPR006074	GTP1/OBG, conserved site
IPR012675	Beta-grasp domain
IPR012676	TGS-like
IPR027417	P-loop containing nucleoside triphosphate hydrolase
IPR031167	OBG-type guanine nucleotide-binding (G) domain
IPR031662	GTP binding protein, second domain

Pubmed ID	Author	Year	Title
22951915	Haozi et al.	2012	Altered gene expression profile in cumulus cells of mature MII oocytes from patients with polycystic ovary syndrome

Gene Symbol	Entrez ID	Uniprot ID	Score
DRG1	4733	Q9Y295	0.06
IFRD2	7866	Q12894	0.49
KIF23	9493	Q02241	0.49
CAND2	23066	O75155	0.49
CAND1	55832	Q86VP6	0.49
NAA15	80155	Q9BXJ9	0.49
LYL1	4066	P12980	0.52
SKIL	6498	P12757	0.63
TAL1	6886	P17542	0.63
COIL	8161	P38432	0.63
STK16	8576	O75716	0.63
CLDN1	9076	O95832	0.63
BCL2L11	10018	O43521	0.63
LRRC41	10489	Q15345	0.63
NTMT1	28989	Q9BV86	0.63
HAO1	54363	Q9UJM8	0.63
SSX2IP	117178	Q9Y2D8	0.63
PHC2	1912	Q8IXK0	0.73
ZC3H15	55854	Q8WU90	0.89
FEN1	2237	P39748	0.49
UBE2I	7329	P63279	0.52
BARD1	580	Q99728	0.63
BRCA1	672	P38398	0.63
CAPNS1	826	P04632	0.63
CDC5L	988	Q99459	0.63
FN1	2335	P02751	0.63
SFN	2810	P31947	0.63
GRB2	2885	P62993	0.63
HDGF	3068	P51858	0.63
HLA-B	3106	P30480	0.63
HSPA4	3308	P34932	0.63
ITGA4	3676	P13612	0.63
JUN	3725	P05412	0.63
MCC	4163	P23508	0.63
NTRK1	4914	P04629	0.63
SUMO2	6613	P61956	0.63
STAU1	6780	O95793	0.63
STK4	6789	Q13043	0.63
SUMO1	7341	P63165	0.63
XPO1	7514	O14980	0.63
YWHAZ	7534	P63104	0.63
CUL2	8453	Q13617	0.63
KIAA0101	9768	Q15004	0.63
CUL7	9820	Q14999	0.63
UBD	10537	O15205	0.63
SNW1	22938	Q13573	0.63
PAXIP1	22976	Q6ZW49	0.63
FTSJ1	24140	Q9UET6	0.63
WWOX	51741	Q9NZC7	0.63
RIOK2	55781	Q9BVS4	0.63
HECW2	57520	Q9P2P5	0.63
CCDC8	83987	Q9H0W5	0.63
SRPK2	6733	P78362	0.70
ABL1	25	P00519	0.72
PHKG2	5261	P15735	0.72
RPL10	6134	P27635	0.72
MAST3	23031	O60307	0.72
VCAM1	7412	P19320	0.82
RWDD1	51389	Q9H446	0.95