BP

GO:0007399

nervous system development

The process whose specific outcome is the progression of nervous tissue over time, from its formation to its mature state.

ISS

BP

GO:0030514

negative regulation of BMP signaling pathway

Any process that stops, prevents, or reduces the frequency, rate or extent of the BMP signaling pathway.

IDA

BP

GO:0035582

sequestering of BMP in extracellular matrix

Confining a bone morphogenetic protein (BMP) to the extracellular matrix (ECM), such that it is separated from other components of the signaling pathway, including its cell surface receptor. Bone morphogenetic proteins (BMPs) are secreted as homodimers, non-covalently associated with N-terminal pro-peptides, and are targeted to the extracellular matrix through interaction with matrix proteins.

ISS

BP

GO:0038098

sequestering of BMP from receptor via BMP binding

Binding to a bone morphogenetic protein (BMP) in the extracellular region, and inhibiting BMP signaling by preventing BMP from binding to its cell surface receptor.

IDA

BP

GO:0045666

positive regulation of neuron differentiation

Any process that activates or increases the frequency, rate or extent of neuron differentiation.

ISS

BP

GO:0048263

determination of dorsal identity

Determination of the identity of part of an organism or organ where those parts are of the type that occur in the dorsal region. Identity is considered to be the aggregate of characteristics by which a structure is recognized.

ISS

BP

GO:0048812

neuron projection morphogenesis

The process in which the anatomical structures of a neuron projection are generated and organized. A neuron projection is any process extending from a neural cell, such as axons or dendrites.

ISS

BP

GO:0090027

negative regulation of monocyte chemotaxis

Any process that decreases the frequency, rate, or extent of monocyte chemotaxis.

ISS

CC

GO:0005615

extracellular space

That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.

IC

MF

GO:0016015

morphogen activity

Acts as a trigger for a pattern specification process when present at a specific concentration within a gradient.

ISS

MF

GO:0036122

BMP binding

Interacting selectively and non-covalently with a member of the bone morphogenetic protein (BMP) family.

ISS

MF

GO:0042803

protein homodimerization activity

Interacting selectively and non-covalently with an identical protein to form a homodimer.

IMP