Protein Description

Gene Symbol NAP1L1
Entrez ID 4673
Uniprot ID P55209
Description nucleosome assembly protein 1-like 1
Chromosomal Location chr12: 76,036,587-76,085,033
Ontology GO ID GO Term Definition Evidence

BP

GO:0006260

DNA replication

The cellular metabolic process in which a cell duplicates one or more molecules of DNA. DNA replication begins when specific sequences, known as origins of replication, are recognized and bound by initiation proteins, and ends when the original DNA molecule has been completely duplicated and the copies topologically separated. The unit of replication usually corresponds to the genome of the cell, an organelle, or a virus. The template for replication can either be an existing DNA molecule or RNA.

TAS

BP

GO:0006334

nucleosome assembly

The aggregation, arrangement and bonding together of a nucleosome, the beadlike structural units of eukaryotic chromatin composed of histones and DNA.

IEA

BP

GO:0008284

positive regulation of cell proliferation

Any process that activates or increases the rate or extent of cell proliferation.

TAS

CC

GO:0005634

nucleus

A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

IEA

CC

GO:0016020

membrane

A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.

IDA

CC

GO:0042470

melanosome

A tissue-specific, membrane-bounded cytoplasmic organelle within which melanin pigments are synthesized and stored. Melanosomes are synthesized in melanocyte cells.

IEA

MF

GO:0005515

protein binding

Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).

IPI

MF

GO:0044822

poly(A) RNA binding

Interacting non-covalently with a poly(A) RNA, a RNA molecule which has a tail of adenine bases.

IDA

Domain ID Description

IPR002164

Nucleosome assembly protein (NAP)

No pathways found.

UMLS CUI UMLS Term

C0028754

Obesity

Tissue Cell Type

adrenal gland

glandular cells

appendix

glandular cells

appendix

lymphoid tissue

bone marrow

hematopoietic cells

breast

glandular cells

breast

myoepithelial cells

bronchus

respiratory epithelial cells

cerebellum

Purkinje cells

cerebral cortex

neuropil

cervix, uterine

glandular cells

colon

endothelial cells

colon

glandular cells

colon

peripheral nerve/ganglion

duodenum

glandular cells

endometrium

cells in endometrial stroma

endometrium

glandular cells

epididymis

glandular cells

esophagus

squamous epithelial cells

fallopian tube

glandular cells

gallbladder

glandular cells

kidney

cells in glomeruli

kidney

cells in tubules

nasopharynx

respiratory epithelial cells

oral mucosa

squamous epithelial cells

pancreas

exocrine glandular cells

placenta

trophoblastic cells

prostate

glandular cells

rectum

glandular cells

salivary gland

glandular cells

seminal vesicle

glandular cells

skin

keratinocytes

skin

Langerhans

skin

melanocytes

skin

epidermal cells

small intestine

glandular cells

soft tissue

peripheral nerve

soft tissue

fibroblasts

stomach

glandular cells

testis

cells in seminiferous ducts

thyroid gland

glandular cells

tonsil

germinal center cells

tonsil

squamous epithelial cells

urinary bladder

urothelial cells

vagina

squamous epithelial cells

No databases found.

Pubmed ID Author Year Title

22617121

Ouandaogo et al.

2012

Differences in transcriptomic profiles of human cumulus cells isolated from oocytes at GV, MI and MII stages after in vivo andin vitro oocyte maturation

Gene Symbol Entrez ID Uniprot ID Score

SMAD2

4087

Q15796

0.49

MDM2

4193

Q00987

0.49

MYC

4609

P01106

0.49

NPM1

4869

P06748

0.49

RAC3

5881

P60763

0.49

RBBP4

5928

Q09028

0.49

RPL5

6125

P46777

0.49

RPL11

6135

P62913

0.49

RPL12

6136

P30050

0.49

RPL15

6138

P61313

0.49

RPL31

6160

P62899

0.49

RPS3

6188

P23396

0.49

RPS3A

6189

P61247

0.49

RPS4X

6191

P62701

0.49

SET

6418

Q01105

0.49

SUPT4H1

6827

P63272

0.49

RPL14

9045

P50914

0.49

UBA2

10054

Q9UBT2

0.49

PDCD4

27250

Q53EL6

0.49

SCHIP1

29970

Q9P0W5

0.49

RPS10P5

93144

Q9NQ39

0.49

RPL9; RPL9P7; RPL9P8; RPL9P9

6133

P32969

0.49

RPL10A

4736

P62906

0.56

RPL37A

6168

P61513

0.56

RPS6

6194

P62753

0.56

SP1

6667

P08047

0.56

TP53

7157

P04637

0.59

EIF1AX

1964

P47813

0.63

FNTA

2339

P49354

0.63

FNTB

2342

P49356

0.63

HLA-B

3106

P30480

0.63

HSPB1

3315

P04792

0.63

RPL17

6139

P18621

0.63

RPL23A

6147

P62750

0.63

RPL24

6152

P83731

0.63

RPL36AL

6166

Q969Q0

0.63

RPS15

6209

P62841

0.63

TPX2

22974

Q9ULW0

0.63

NOP16

51491

Q9Y3C1

0.63

RIC8B

55188

Q9NVN3

0.63

EPB41L5

57669

Q9HCM4

0.63

UBE2O

63893

Q9C0C9

0.63

FSD1

79187

Q9BTV5

0.63

MED10

84246

Q9BTT4

0.63

PES1

23481

O00541

0.65

RPL36A

6173

P83881

0.70

SDAD1

55153

Q9NVU7

0.70

HIST1H2AG; HIST1H2AI; HIST1H2AK; HIST1H2AL; HIST1H2AM

8329

P0C0S8

0.70

HIST2H2AB

317772

Q8IUE6

0.72

TTLL10

254173

Q6ZVT0

0.73

NAP1L4

4676

Q99733

0.74

CREBBP

1387

Q92793

0.75

NR2F6

2063

P10588

0.75

COPS2

9318

P61201

0.75

EP300

2033

Q09472

0.86

NAP1L1

4673

P55209

0.88

DCTN1

1639

Q14203

0.49

GTF2F2

2963

P13984

0.49

NCL

4691

P19338

0.49

EIF3C

8663

Q99613

0.49

EIF3H

8667

O15372

0.49

CDC23

8697

Q9UJX2

0.49

ALYREF

10189

Q86V81

0.49

SMAP

10944

O00193

0.49

WDR43

23160

Q15061

0.49

RPGRIP1

57096

Q96KN7

0.49

SPICE1

152185

Q8N0Z3

0.49

CEP120

153241

Q8N960

0.49

LCA5

167691

Q86VQ0

0.49

CD247

919

P20963

0.56

GTF2B

2959

Q00403

0.56

PHB

5245

P35232

0.56

SSRP1

6749

Q08945

0.56

SUPT16H

11198

Q9Y5B9

0.56

IPO9

55705

Q96P70

0.56

CAPZA2

830

P47755

0.63

CSNK2B

1460

P67870

0.63

DBN1

1627

Q16643

0.63

DLST

1743

P36957

0.63

ELAVL1

1994

Q15717

0.63

FUS

2521

P35637

0.63

HBA1 HBA2

3039

P69905

0.63

JUN

3725

P05412

0.63

KCND3

3752

Q9UK17

0.63

LGALS3

3958

P17931

0.63

MCM2

4171

P49736

0.63

MTNR1A

4543

P48039

0.63

MYH9

4627

P35579

0.63

NOS2

4843

P35228

0.63

NTRK1

4914

P04629

0.63

OSBP

5007

P22059

0.63

RAD21

5885

O60216

0.63

SUMO2

6613

P61956

0.63

TFE3

7030

P19532

0.63

TRAF6

7189

Q9Y4K3

0.63

SUMO1

7341

P63165

0.63

XPO1

7514

O14980

0.63

CUL5

8065

Q93034

0.63

CUL4B

8450

Q13620

0.63

CUL3

8452

Q13618

0.63

CUL2

8453

Q13617

0.63

CUL1

8454

Q13616

0.63

RANBP3

8498

Q9H6Z4

0.63

ATG5

9474

Q9H1Y0

0.63

BAG3

9531

O95817

0.63

IKBKE

9641

Q14164

0.63

KIAA0101

9768

Q15004

0.63

CUL7

9820

Q14999

0.63

HUWE1

10075

Q7Z6Z7

0.63

COPS5

10987

Q92905

0.63

GABARAP

11337

O95166

0.63

GABARAPL2

11345

P60520

0.63

LARP1

23367

Q6PKG0

0.63

GABARAPL1

23710

Q9H0R8

0.63

FTSJ1

24140

Q9UET6

0.63

POT1

25913

Q9NUX5

0.63

FBXO25

26260

Q8TCJ0

0.63

CHORDC1

26973

Q9UHD1

0.63

SIRT7

51547

Q9NRC8

0.63

THUMPD1

55623

Q9NXG2

0.63

RIOK2

55781

Q9BVS4

0.63

CAND1

55832

Q86VP6

0.63

PCDHB15

56121

Q9Y5E8

0.63

NOM1

64434

Q5C9Z4

0.63

LRRK1

79705

Q38SD2

0.63

MYO19

80179

Q96H55

0.63

EIF2A

83939

Q9BY44

0.63

MAP1LC3A

84557

Q9H492

0.63

ZNF622

90441

Q969S3

0.63

QSOX2

169714

Q6ZRP7

0.63

ANKRD23

200539

Q86SG2

0.63

HIST1H2BA

255626

Q96A08

0.63

ASPM

259266

Q8IZT6

0.63

NAP1L5

266812

Q96NT1

0.63

C1QTNF9

338872

P0C862

0.63

CSNK2A1

1457

P68400

0.68

CDK2

1017

P24941

0.70

PSMD4

5710

P55036

0.70

NOP56

10528

O00567

0.70

ARRB2

409

P32121

0.72

ILK

3611

Q13418

0.72

JAK2

3717

O60674

0.72

JAK3

3718

P52333

0.72

TNFRSF1A

7132

P19438

0.72

TRAF1

7185

Q13077

0.72

TRAF2

7186

Q12933

0.72

TRADD

8717

Q15628

0.72

IQCB1

9657

Q15051

0.72

TANK

10010

Q92844

0.72

RPL6

6128

Q02878

0.73

MAGED2

10916

Q9UNF1

0.73

TERF1

7013

P54274

0.75