| Gene Symbol | MYBPC1 |
| Entrez ID | 4604 |
| Uniprot ID | Q00872 |
| Description | myosin binding protein C, slow type |
| Chromosomal Location | chr12: 101,568,353-101,686,018 |
| Ontology | GO ID | GO Term | Definition | Evidence |
|---|---|---|---|---|
BP | GO:0007155 | cell adhesion |
The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules. | IEA |
BP | GO:0030049 | muscle filament sliding |
The sliding of actin thin filaments and myosin thick filaments past each other in muscle contraction. This involves a process of interaction of myosin located on a thick filament with actin located on a thin filament. During this process ATP is split and forces are generated. | TAS |
BP | GO:1903955 | positive regulation of protein targeting to mitochondrion |
Any process that activates or increases the frequency, rate or extent of protein targeting to mitochondrion. | IMP |
CC | GO:0005829 | cytosol |
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. | TAS |
CC | GO:0030016 | myofibril |
The contractile element of skeletal and cardiac muscle; a long, highly organized bundle of actin, myosin, and other proteins that contracts by a sliding filament mechanism. | ISS |
CC | GO:0032982 | myosin filament |
A protein complex containing myosin heavy chains, plus associated light chains and other proteins, in which the myosin heavy chains are arranged into a filament. | IEA |
MF | GO:0003779 | actin binding |
Interacting selectively and non-covalently with monomeric or multimeric forms of actin, including actin filaments. | IEA |
MF | GO:0008307 | structural constituent of muscle |
The action of a molecule that contributes to the structural integrity of a muscle fiber. | TAS |
MF | GO:0031432 | titin binding |
Interacting selectively and non-covalently with titin, any of a family of giant proteins found in striated and smooth muscle. In striated muscle, single titin molecules span half the sarcomere, with their N- and C-termini in the Z-disc and M-line, respectively. | ISS |
| Domain ID | Description |
|---|---|
IPR003598 | Immunoglobulin subtype 2 |
IPR003599 | Immunoglobulin subtype |
IPR003961 | Fibronectin type III |
IPR007110 | Immunoglobulin-like domain |
IPR013098 | Immunoglobulin I-set |
IPR013783 | Immunoglobulin-like fold |
| Pathway ID | Pathway Term | Pathway Source |
|---|---|---|
WP383 | Striated Muscle Contraction | WikiPathways |
| Tissue | Cell Type |
|---|---|
skeletal muscle | myocytes |
| Pubmed ID | Author | Year | Title |
|---|---|---|---|
22617121 | Ouandaogo et al. | 2012 | Differences in transcriptomic profiles of human cumulus cells isolated from oocytes at GV, MI and MII stages after in vivo andin vitro oocyte maturation |
| Gene Symbol | Entrez ID | Uniprot ID | Score |
|---|---|---|---|
FLNB | 2317 | O75369 | 0.63 |
MYBPC2 | 4606 | Q14324 | 0.63 |
C1QTNF9 | 338872 | P0C862 | 0.63 |
TTN | 7273 | Q8WZ42 | 0.75 |
CALM2 | 805 | P62158 | 0.56 |
CALM3 | 808 | P62158 | 0.56 |
ACO1 | 48 | P21399 | 0.63 |
CAPN3 | 825 | P20807 | 0.63 |
MEOX2 | 4223 | P50222 | 0.63 |
RAF1 | 5894 | P04049 | 0.63 |
SGCG | 6445 | Q13326 | 0.63 |
DYSF | 8291 | O75923 | 0.63 |
ASH2L | 9070 | Q9UBL3 | 0.63 |
DNAJB6 | 10049 | O75190 | 0.63 |
KLHL41 | 10324 | O60662 | 0.63 |
DNAJB5 | 25822 | O75953 | 0.63 |
ANKRD1 | 27063 | Q15327 | 0.63 |
CLIP4 | 79745 | Q8N3C7 | 0.63 |
TRIM55 | 84675 | Q9BYV6 | 0.63 |
TRIM63 | 84676 | Q969Q1 | 0.63 |
AMOT | 154796 | Q4VCS5 | 0.63 |
NCF1 | 653361 | P14598 | 0.63 |
FHL2 | 2274 | Q14192 | 0.72 |
FHL3 | 2275 | Q13643 | 0.72 |
USP25 | 29761 | Q9UHP3 | 0.72 |
FHL1 | 2273 | Q13642 | 0.88 |