Protein Description

Gene Symbol MYBPC1
Entrez ID 4604
Uniprot ID Q00872
Description myosin binding protein C, slow type
Chromosomal Location chr12: 101,568,353-101,686,018
Ontology GO ID GO Term Definition Evidence

BP

GO:0007155

cell adhesion

The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules.

IEA

BP

GO:0030049

muscle filament sliding

The sliding of actin thin filaments and myosin thick filaments past each other in muscle contraction. This involves a process of interaction of myosin located on a thick filament with actin located on a thin filament. During this process ATP is split and forces are generated.

TAS

BP

GO:1903955

positive regulation of protein targeting to mitochondrion

Any process that activates or increases the frequency, rate or extent of protein targeting to mitochondrion.

IMP

CC

GO:0005829

cytosol

The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

TAS

CC

GO:0030016

myofibril

The contractile element of skeletal and cardiac muscle; a long, highly organized bundle of actin, myosin, and other proteins that contracts by a sliding filament mechanism.

ISS

CC

GO:0032982

myosin filament

A protein complex containing myosin heavy chains, plus associated light chains and other proteins, in which the myosin heavy chains are arranged into a filament.

IEA

MF

GO:0003779

actin binding

Interacting selectively and non-covalently with monomeric or multimeric forms of actin, including actin filaments.

IEA

MF

GO:0008307

structural constituent of muscle

The action of a molecule that contributes to the structural integrity of a muscle fiber.

TAS

MF

GO:0031432

titin binding

Interacting selectively and non-covalently with titin, any of a family of giant proteins found in striated and smooth muscle. In striated muscle, single titin molecules span half the sarcomere, with their N- and C-termini in the Z-disc and M-line, respectively.

ISS

Domain ID Description

IPR003598

Immunoglobulin subtype 2

IPR003599

Immunoglobulin subtype

IPR003961

Fibronectin type III

IPR007110

Immunoglobulin-like domain

IPR013098

Immunoglobulin I-set

IPR013783

Immunoglobulin-like fold

Pathway ID Pathway Term Pathway Source

WP383

Striated Muscle Contraction

WikiPathways

No diseases found.

Tissue Cell Type

skeletal muscle

myocytes

No databases found.

Pubmed ID Author Year Title

22617121

Ouandaogo et al.

2012

Differences in transcriptomic profiles of human cumulus cells isolated from oocytes at GV, MI and MII stages after in vivo andin vitro oocyte maturation

Gene Symbol Entrez ID Uniprot ID Score

FLNB

2317

O75369

0.63

MYBPC2

4606

Q14324

0.63

C1QTNF9

338872

P0C862

0.63

TTN

7273

Q8WZ42

0.75

CALM2

805

P62158

0.56

CALM3

808

P62158

0.56

ACO1

48

P21399

0.63

CAPN3

825

P20807

0.63

MEOX2

4223

P50222

0.63

RAF1

5894

P04049

0.63

SGCG

6445

Q13326

0.63

DYSF

8291

O75923

0.63

ASH2L

9070

Q9UBL3

0.63

DNAJB6

10049

O75190

0.63

KLHL41

10324

O60662

0.63

DNAJB5

25822

O75953

0.63

ANKRD1

27063

Q15327

0.63

CLIP4

79745

Q8N3C7

0.63

TRIM55

84675

Q9BYV6

0.63

TRIM63

84676

Q969Q1

0.63

AMOT

154796

Q4VCS5

0.63

NCF1

653361

P14598

0.63

FHL2

2274

Q14192

0.72

FHL3

2275

Q13643

0.72

USP25

29761

Q9UHP3

0.72

FHL1

2273

Q13642

0.88