Gene Symbol | MKLN1 |
Entrez ID | 4289 |
Uniprot ID | Q9UL63 |
Description | muskelin 1 |
Chromosomal Location | chr7: 131,110,096-131,496,636 |
Ontology | GO ID | GO Term | Definition | Evidence |
---|---|---|---|---|
BP |
GO:0007160 |
cell-matrix adhesion |
The binding of a cell to the extracellular matrix via adhesion molecules. |
ISS |
BP |
GO:0007165 |
signal transduction |
The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell. |
NAS |
BP |
GO:0008360 |
regulation of cell shape |
Any process that modulates the surface configuration of a cell. |
ISS |
BP |
GO:0031532 |
actin cytoskeleton reorganization |
A process that is carried out at the cellular level which results in dynamic structural changes to the arrangement of constituent parts of cytoskeletal structures comprising actin filaments and their associated proteins. |
ISS |
CC |
GO:0001726 |
ruffle |
Projection at the leading edge of a crawling cell; the protrusions are supported by a microfilament meshwork. |
ISS |
CC |
GO:0005829 |
cytosol |
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. |
ISS |
CC |
GO:0005938 |
cell cortex |
The region of a cell that lies just beneath the plasma membrane and often, but not always, contains a network of actin filaments and associated proteins. |
ISS |
Domain ID | Description |
---|---|
IPR006594 |
LIS1 homology motif |
IPR006595 |
CTLH, C-terminal LisH motif |
IPR006652 |
Kelch repeat type 1 |
IPR008979 |
Galactose-binding domain-like |
IPR010565 |
Muskelin, N-terminal |
IPR011043 |
Galactose oxidase/kelch, beta-propeller |
IPR015915 |
Kelch-type beta propeller |
IPR015916 |
Galactose oxidase, beta-propeller |
Tissue | Cell Type |
---|---|
appendix |
glandular cells |
caudate |
neuronal cells |
cerebellum |
cells in granular layer |
cerebellum |
Purkinje cells |
cerebral cortex |
neuropil |
colon |
glandular cells |
duodenum |
glandular cells |
gallbladder |
glandular cells |
kidney |
cells in tubules |
parathyroid gland |
glandular cells |
stomach |
glandular cells |
Pubmed ID | Author | Year | Title |
---|---|---|---|
22617121 |
Ouandaogo et al. |
2012 |
Differences in transcriptomic profiles of human cumulus cells isolated from oocytes at GV, MI and MII stages after in vivo andin vitro oocyte maturation |
22951915 |
Haozi et al. |
2012 |
Altered gene expression profile in cumulus cells of mature MII oocytes from patients with polycystic ovary syndrome |
Gene Symbol | Entrez ID | Uniprot ID | Score |
---|---|---|---|
NUDCD2 |
134492 |
Q8WVJ2 |
0.49 |
MKLN1 |
4289 |
Q9UL63 |
0.63 |
MAEA |
10296 |
Q7L5Y9 |
0.63 |
GID8 |
54994 |
Q9NWU2 |
0.68 |
RMND5A |
64795 |
Q9H871 |
0.73 |
ADCYAP1 |
116 |
P18509 |
0.63 |
ELAVL1 |
1994 |
Q15717 |
0.63 |
GDNF |
2668 |
P39905 |
0.63 |
GPS2 |
2874 |
Q13227 |
0.63 |
HLA-DPB1 |
3115 |
P04440 |
0.63 |
MMP7 |
4316 |
P09237 |
0.63 |
PRG2 |
5553 |
P13727 |
0.63 |
SFRP2 |
6423 |
Q96HF1 |
0.63 |
SOX2 |
6657 |
P48431 |
0.63 |
TDGF1 |
6997 |
P13385 |
0.63 |
GGH |
8836 |
Q92820 |
0.63 |
NR1H3 |
10062 |
Q13133 |
0.63 |
IFI30 |
10437 |
P13284 |
0.63 |
LAMTOR5 |
10542 |
O43504 |
0.63 |
ARMC8 |
25852 |
Q8IUR7 |
0.63 |
MRPL4 |
51073 |
Q9BYD3 |
0.63 |
SLX4 |
84464 |
Q8IY92 |
0.63 |
UNK |
85451 |
Q9C0B0 |
0.63 |
GLIPR1L2 |
144321 |
Q4G1C9 |
0.63 |
PTGER3 |
5733 |
P43115 |
0.68 |
DYNC1H1 |
1778 |
Q14204 |
0.72 |
MYC |
4609 |
P01106 |
0.76 |
RNPS1 |
10921 |
Q15287 |
0.76 |
RANBP9 |
10048 |
Q96S59 |
0.87 |