Gene Symbol | FAS |
Entrez ID | 355 |
Uniprot ID | P25445 |
Description | Fas cell surface death receptor |
Chromosomal Location | chr10: 88,990,582-89,015,785 |
Ontology | GO ID | GO Term | Definition | Evidence |
---|---|---|---|---|
BP |
GO:0002377 |
immunoglobulin production |
The appearance of immunoglobulin due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. |
IEA |
BP |
GO:0003014 |
renal system process |
A organ system process carried out by any of the organs or tissues of the renal system. The renal system maintains fluid balance, and contributes to electrolyte balance, acid/base balance, and disposal of nitrogenous waste products. In humans, the renal system comprises a pair of kidneys, a pair of ureters, urinary bladder, urethra, sphincter muscle and associated blood vessels; in other species, the renal system may comprise related structures (e.g., nephrocytes and malpighian tubules in Drosophila). |
IEA |
BP |
GO:0006461 |
protein complex assembly |
The aggregation, arrangement and bonding together of a set of components to form a protein complex. |
TAS |
BP |
GO:0006915 |
apoptotic process |
A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died. |
IDA |
BP |
GO:0006919 |
activation of cysteine-type endopeptidase activity involved in apoptotic process |
Any process that initiates the activity of the inactive enzyme cysteine-type endopeptidase in the context of an apoptotic process. |
TAS |
BP |
GO:0006924 |
activation-induced cell death of T cells |
A T cell apoptotic process that occurs towards the end of the expansion phase following the initial activation of mature T cells by antigen and is triggered by T cell receptor stimulation and signals transmitted via various surface-expressed members of the TNF receptor family such as Fas ligand, Fas, and TNF and the p55 and p75 TNF receptors. |
IEA |
BP |
GO:0006925 |
inflammatory cell apoptotic process |
Any apoptotic process in an inflammatory cell, any cell participating in the inflammatory response to a foreign substance e.g. neutrophil, macrophage. |
IEA |
BP |
GO:0006954 |
inflammatory response |
The immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The process is characterized by local vasodilation, extravasation of plasma into intercellular spaces and accumulation of white blood cells and macrophages. |
IBA |
BP |
GO:0006955 |
immune response |
Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat. |
IBA |
BP |
GO:0007165 |
signal transduction |
The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell. |
TAS |
BP |
GO:0007420 |
brain development |
The process whose specific outcome is the progression of the brain over time, from its formation to the mature structure. Brain development begins with patterning events in the neural tube and ends with the mature structure that is the center of thought and emotion. The brain is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.). |
IBA |
BP |
GO:0007623 |
circadian rhythm |
Any biological process in an organism that recurs with a regularity of approximately 24 hours. |
IEA |
BP |
GO:0008625 |
extrinsic apoptotic signaling pathway via death domain receptors |
A series of molecular signals in which a signal is conveyed from the cell surface to trigger the apoptotic death of a cell. The pathway starts with a ligand binding to a death domain receptor on the cell surface, and ends when the execution phase of apoptosis is triggered. |
IBA |
BP |
GO:0009636 |
response to toxic substance |
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a toxic stimulus. |
IEA |
BP |
GO:0010467 |
gene expression |
The process in which a gene's sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form. |
IEA |
BP |
GO:0019724 |
B cell mediated immunity |
Any process involved with the carrying out of an immune response by a B cell, through, for instance, the production of antibodies or cytokines, or antigen presentation to T cells. |
IEA |
BP |
GO:0032464 |
positive regulation of protein homooligomerization |
Any process that activates or increases the frequency, rate or extent of protein homooligomerization. |
IEA |
BP |
GO:0032496 |
response to lipopolysaccharide |
Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipopolysaccharide stimulus; lipopolysaccharide is a major component of the cell wall of gram-negative bacteria. |
IBA |
BP |
GO:0033209 |
tumor necrosis factor-mediated signaling pathway |
A series of molecular signals initiated by the binding of a tumor necrosis factor to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. |
IEA |
BP |
GO:0042127 |
regulation of cell proliferation |
Any process that modulates the frequency, rate or extent of cell proliferation. |
IBA |
BP |
GO:0042981 |
regulation of apoptotic process |
Any process that modulates the occurrence or rate of cell death by apoptotic process. |
NAS|TAS |
BP |
GO:0043065 |
positive regulation of apoptotic process |
Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process. |
IDA|IMP |
BP |
GO:0043066 |
negative regulation of apoptotic process |
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process. |
TAS |
BP |
GO:0043281 |
regulation of cysteine-type endopeptidase activity involved in apoptotic process |
Any process that modulates the activity of a cysteine-type endopeptidase involved in apoptosis. |
IBA |
BP |
GO:0043410 |
positive regulation of MAPK cascade |
Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the MAPK cascade. |
IBA |
BP |
GO:0045060 |
negative thymic T cell selection |
The process of elimination of immature T cells in the thymus which react strongly with self-antigens. |
IEA |
BP |
GO:0045619 |
regulation of lymphocyte differentiation |
Any process that modulates the frequency, rate or extent of lymphocyte differentiation. |
IEA |
BP |
GO:0045637 |
regulation of myeloid cell differentiation |
Any process that modulates the frequency, rate or extent of myeloid cell differentiation. |
IEA |
BP |
GO:0048536 |
spleen development |
The process whose specific outcome is the progression of the spleen over time, from its formation to the mature structure. The spleen is a large vascular lymphatic organ composed of white and red pulp, involved both in hemopoietic and immune system functions. |
IEA |
BP |
GO:0050869 |
negative regulation of B cell activation |
Any process that stops, prevents, or reduces the frequency, rate or extent of B cell activation. |
IEA |
BP |
GO:0051260 |
protein homooligomerization |
The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of identical component monomers. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer. |
IEA |
BP |
GO:0051384 |
response to glucocorticoid |
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucocorticoid stimulus. Glucocorticoids are hormonal C21 corticosteroids synthesized from cholesterol with the ability to bind with the cortisol receptor and trigger similar effects. Glucocorticoids act primarily on carbohydrate and protein metabolism, and have anti-inflammatory effects. |
IEA |
BP |
GO:0070230 |
positive regulation of lymphocyte apoptotic process |
Any process that activates or increases the frequency, rate or extent of lymphocyte death by apoptotic process. |
IEA |
BP |
GO:0071260 |
cellular response to mechanical stimulus |
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mechanical stimulus. |
IEP |
BP |
GO:0071285 |
cellular response to lithium ion |
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lithium (Li+) ion stimulus. |
IEA |
BP |
GO:0071455 |
cellular response to hyperoxia |
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating increased oxygen tension. |
IMP |
BP |
GO:0097049 |
motor neuron apoptotic process |
Any apoptotic process in a motor neuron, an efferent neuron that passes from the central nervous system or a ganglion toward or to a muscle and conducts an impulse that causes movement. |
IEA |
BP |
GO:0097190 |
apoptotic signaling pathway |
A series of molecular signals which triggers the apoptotic death of a cell. The pathway starts with reception of a signal, and ends when the execution phase of apoptosis is triggered. |
TAS |
BP |
GO:0097191 |
extrinsic apoptotic signaling pathway |
A series of molecular signals in which a signal is conveyed from the cell surface to trigger the apoptotic death of a cell. The pathway starts with either a ligand binding to a cell surface receptor, or a ligand being withdrawn from a cell surface receptor (e.g. in the case of signaling by dependence receptors), and ends when the execution phase of apoptosis is triggered. |
IMP |
BP |
GO:0097192 |
extrinsic apoptotic signaling pathway in absence of ligand |
A series of molecular signals in which a signal is conveyed from the cell surface to trigger the apoptotic death of a cell. The pathway starts with withdrawal of a ligand from a cell surface receptor, and ends when the execution phase of apoptosis is triggered. |
IEA |
BP |
GO:0097284 |
hepatocyte apoptotic process |
Any apoptotic process in a hepatocyte, the main structural component of the liver. |
IEA |
BP |
GO:0097296 |
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway |
Any process that initiates the activity of an inactive cysteine-type endopeptidase involved in the apoptotic signaling pathway. |
TAS |
BP |
GO:0097527 |
necroptotic signaling pathway |
A series of molecular signals which triggers the necroptotic death of a cell. The pathway starts with reception of a signal, is characterized by activation of receptor-interacting serine/threonine-protein kinase 1 and/or 3 (RIPK1/3, also called RIP1/3), and ends when the execution phase of necroptosis is triggered. |
IMP |
BP |
GO:1902041 |
regulation of extrinsic apoptotic signaling pathway via death domain receptors |
Any process that modulates the frequency, rate or extent of extrinsic apoptotic signaling pathway via death domain receptors. |
TAS |
BP |
GO:1902042 |
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors |
Any process that stops, prevents or reduces the frequency, rate or extent of extrinsic apoptotic signaling pathway via death domain receptors. |
TAS |
BP |
GO:2001241 |
positive regulation of extrinsic apoptotic signaling pathway in absence of ligand |
Any process that activates or increases the frequency, rate or extent of extrinsic apoptotic signaling pathway in absence of ligand. |
IEA |
CC |
GO:0005634 |
nucleus |
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
IBA|IDA |
CC |
GO:0005737 |
cytoplasm |
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
IDA |
CC |
GO:0005829 |
cytosol |
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. |
NAS |
CC |
GO:0005886 |
plasma membrane |
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
IDA|IMP|TAS |
CC |
GO:0005887 |
integral component of plasma membrane |
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
IBA |
CC |
GO:0009897 |
external side of plasma membrane |
The leaflet of the plasma membrane that faces away from the cytoplasm and any proteins embedded or anchored in it or attached to its surface. |
IEA |
CC |
GO:0009986 |
cell surface |
The external part of the cell wall and/or plasma membrane. |
IDA |
CC |
GO:0031264 |
death-inducing signaling complex |
A protein complex formed by the association of signaling proteins with a death receptor upon ligand binding. The complex includes procaspases and death domain-containing proteins in addition to the ligand-bound receptor, and may control the activation of caspases 8 and 10. |
IDA |
CC |
GO:0031265 |
CD95 death-inducing signaling complex |
A protein complex formed upon binding of Fas/CD95/APO-1 to its ligand. The complex includes FADD/Mort1, procaspase-8/10 and c-FLIP in addition to the ligand-bound receptor. |
IDA |
CC |
GO:0043005 |
neuron projection |
A prolongation or process extending from a nerve cell, e.g. an axon or dendrite. |
IBA |
CC |
GO:0045121 |
membrane raft |
Any of the small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes. Small rafts can sometimes be stabilized to form larger platforms through protein-protein and protein-lipid interactions. |
IDA |
CC |
GO:0070062 |
extracellular exosome |
A membrane-bounded vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm. |
IDA |
MF |
GO:0004871 |
signal transducer activity |
Conveys a signal across a cell to trigger a change in cell function or state. A signal is a physical entity or change in state that is used to transfer information in order to trigger a response. |
TAS |
MF |
GO:0004872 |
receptor activity |
Combining with an extracellular or intracellular messenger to initiate a change in cell activity. |
NAS |
MF |
GO:0005031 |
tumor necrosis factor-activated receptor activity |
Combining with tumor necrosis factor, a proinflammatory cytokine produced by monocytes and macrophages, to initiate a change in cell function. |
IBA |
MF |
GO:0005515 |
protein binding |
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules). |
IPI |
MF |
GO:0019900 |
kinase binding |
Interacting selectively and non-covalently with a kinase, any enzyme that catalyzes the transfer of a phosphate group. |
IPI |
Domain ID | Description |
---|---|
IPR000488 |
Death domain |
IPR001368 |
TNFR/NGFR cysteine-rich region |
IPR008063 |
Fas receptor |
IPR011029 |
Death-like domain |
IPR033998 |
Fas receptor, death domain |
IPR033999 |
Fas receptor, N-terminal |
Pathway ID | Pathway Term | Pathway Source |
---|---|---|
hsa01524 |
Platinum drug resistance |
KEGG |
hsa04010 |
MAPK signaling pathway |
KEGG |
hsa04060 |
Cytokine-cytokine receptor interaction |
KEGG |
hsa04115 |
p53 signaling pathway |
KEGG |
hsa04210 |
Apoptosis |
KEGG |
hsa04650 |
Natural killer cell mediated cytotoxicity |
KEGG |
hsa04668 |
TNF signaling pathway |
KEGG |
hsa04932 |
Non-alcoholic fatty liver disease (NAFLD) |
KEGG |
hsa04940 |
Type I diabetes mellitus |
KEGG |
hsa05010 |
Alzheimer's disease |
KEGG |
hsa05142 |
Chagas disease (American trypanosomiasis) |
KEGG |
hsa05143 |
African trypanosomiasis |
KEGG |
hsa05161 |
Hepatitis B |
KEGG |
hsa05162 |
Measles |
KEGG |
hsa05164 |
Influenza A |
KEGG |
hsa05168 |
Herpes simplex infection |
KEGG |
hsa05200 |
Pathways in cancer |
KEGG |
hsa05205 |
Proteoglycans in cancer |
KEGG |
hsa05320 |
Autoimmune thyroid disease |
KEGG |
hsa05330 |
Allograft rejection |
KEGG |
hsa05332 |
Graft-versus-host disease |
KEGG |
WP707 |
DNA Damage Response |
WikiPathways |
WP2059 |
Alzheimers Disease |
WikiPathways |
WP2328 |
Allograft Rejection |
WikiPathways |
WP3611 |
Photodynamic therapy-induced AP-1 survival signaling. |
WikiPathways |
WP384 |
Apoptosis Modulation by HSP70 |
WikiPathways |
WP2507 |
Nanomaterial induced apoptosis |
WikiPathways |
WP236 |
Adipogenesis |
WikiPathways |
WP1530 |
miRNA Regulation of DNA Damage Response |
WikiPathways |
WP382 |
MAPK Signaling Pathway |
WikiPathways |
WP3594 |
Circadian rythm related genes |
WikiPathways |
WP254 |
Apoptosis |
WikiPathways |
WP1772 |
Apoptosis Modulation and Signaling |
WikiPathways |
WP314 |
Fas Ligand (FasL) pathway and Stress induction of Heat Shock Proteins (HSP) regulation |
WikiPathways |
WP69 |
T-Cell antigen Receptor (TCR) Signaling Pathway |
WikiPathways |
WP3888 |
VEGFA-VEGFR2 Signaling Pathway |
WikiPathways |
h_asbcellPathway |
Antigen Dependent B Cell Activation |
BioCarta |
h_bbcellPathway |
Bystander B Cell Activation |
BioCarta |
h_ctlPathway |
CTL mediated immune response against target cells |
BioCarta |
h_fasPathway |
FAS signaling pathway ( CD95 ) |
BioCarta |
h_tcapoptosisPathway |
HIV Induced T Cell Apoptosis |
BioCarta |
h_HivnefPathway |
HIV-I Nef: negative effector of Fas and TNF |
BioCarta |
h_il2rbPathway |
IL-2 Receptor Beta Chain in T cell Activation |
BioCarta |
h_keratinocytePathway |
Keratinocyte Differentiation |
BioCarta |
h_pmlPathway |
Regulation of transcriptional activity by PML |
BioCarta |
h_hsp27Pathway |
Stress Induction of HSP Regulation |
BioCarta |
UMLS CUI | UMLS Term |
---|---|
C0004364 |
Autoimmune Diseases |
C0005695 |
Bladder Neoplasm |
C0007193 |
Cardiomyopathy, Dilated |
C0011853 |
Diabetes Mellitus, Experimental |
C0011860 |
Diabetes Mellitus, Non-Insulin-Dependent |
C0018939 |
Hematological Disease |
C0020532 |
Hypersplenism |
C0023434 |
Chronic Lymphocytic Leukemia |
C0023467 |
Leukemia, Myelocytic, Acute |
C0024121 |
Lung Neoplasms |
C0024535 |
Malaria, Falciparum |
C0026896 |
Myasthenia Gravis |
C0027540 |
Necrosis |
C0032963 |
Pregnancy Complications, Cardiovascular |
C0039338 |
Taste Disorders |
C0079744 |
Diffuse Large B-Cell Lymphoma |
C0079773 |
Lymphoma, T-Cell, Cutaneous |
C0162557 |
Liver Failure, Acute |
C0242488 |
Acute Lung Injury |
C0242698 |
Ventricular Dysfunction, Left |
C0400966 |
Non-Alcoholic Fatty Liver Disease |
C0878544 |
Cardiomyopathies |
C1328840 |
Autoimmune Lymphoproliferative Syndrome |
Tissue | Cell Type |
---|---|
appendix |
glandular cells |
colon |
glandular cells |
gallbladder |
glandular cells |
rectum |
glandular cells |
small intestine |
glandular cells |
testis |
Leydig cells |
Database Name |
---|
DisGeNET |
Pubmed ID | Author | Year | Title |
---|---|---|---|
22951915 |
Haozi et al. |
2012 |
Altered gene expression profile in cumulus cells of mature MII oocytes from patients with polycystic ovary syndrome |
Gene Symbol | Entrez ID | Uniprot ID | Score |
---|---|---|---|
APAF1 |
317 |
O14727 |
0.52 |
CTNNB1 |
1499 |
P35222 |
0.52 |
ARHGDIA |
396 |
P52565 |
0.55 |
MET |
4233 |
P08581 |
0.55 |
MSN |
4478 |
P26038 |
0.55 |
PTPN6 |
5777 |
P29350 |
0.55 |
TNFRSF1A |
7132 |
P19438 |
0.55 |
TNFRSF10B |
8795 |
O14763 |
0.55 |
INPP5D |
3635 |
Q92835 |
0.56 |
TRAF3 |
7187 |
Q13114 |
0.56 |
ARF5 |
381 |
P84085 |
0.63 |
ATP6V0B |
533 |
Q99437 |
0.63 |
CCND3 |
896 |
P30281 |
0.63 |
CRMP1 |
1400 |
Q14194 |
0.63 |
GADD45A |
1647 |
P24522 |
0.63 |
DPH1 |
1801 |
Q9BZG8 |
0.63 |
PEX1 |
5189 |
O43933 |
0.63 |
RB1 |
5925 |
P06400 |
0.63 |
SRC |
6714 |
P12931 |
0.63 |
TUBB2A |
7280 |
Q13885 |
0.63 |
UGDH |
7358 |
O60701 |
0.63 |
WRB |
7485 |
O00258 |
0.63 |
CDYL |
9425 |
Q9Y232 |
0.63 |
CHD1L |
9557 |
Q86WJ1 |
0.63 |
TUBB3 |
10381 |
Q13509 |
0.63 |
TUBB4A |
10382 |
P04350 |
0.63 |
EHD1 |
10938 |
Q9H4M9 |
0.63 |
C14orf1 |
11161 |
Q9UKR5 |
0.63 |
RHOBTB3 |
22836 |
O94955 |
0.63 |
PDXDC1 |
23042 |
Q6P996 |
0.63 |
GPD1L |
23171 |
Q8N335 |
0.63 |
MDN1 |
23195 |
Q9NU22 |
0.63 |
FAF2 |
23197 |
Q96CS3 |
0.63 |
MOCS3 |
27304 |
O95396 |
0.63 |
ACAD9 |
28976 |
Q9H845 |
0.63 |
UBQLN1 |
29979 |
Q9UMX0 |
0.63 |
NDUFAF1 |
51103 |
Q9Y375 |
0.63 |
COX16 |
51241 |
Q9P0S2 |
0.63 |
ECSIT |
51295 |
Q9BQ95 |
0.63 |
METTL13 |
51603 |
Q8N6R0 |
0.63 |
RIF1 |
55183 |
Q5UIP0 |
0.63 |
MAP1S |
55201 |
Q66K74 |
0.63 |
UFSP2 |
55325 |
Q9NUQ7 |
0.63 |
WDR11 |
55717 |
Q9BZH6 |
0.63 |
LRIF1 |
55791 |
Q5T3J3 |
0.63 |
INTS2 |
57508 |
Q9H0H0 |
0.63 |
C17orf75 |
64149 |
Q9HAS0 |
0.63 |
SPATA5L1 |
79029 |
Q9BVQ7 |
0.63 |
FAM118B |
79607 |
Q9BPY3 |
0.63 |
RUFY1 |
80230 |
Q96T51 |
0.63 |
TMX1 |
81542 |
Q9H3N1 |
0.63 |
ABHD11 |
83451 |
Q8NFV4 |
0.63 |
PRAM1 |
84106 |
Q96QH2 |
0.63 |
C19orf52 |
90580 |
Q9BSF4 |
0.63 |
SFXN5 |
94097 |
Q8TD22 |
0.63 |
APOA5 |
116519 |
Q6Q788 |
0.63 |
ALDH16A1 |
126133 |
Q8IZ83 |
0.63 |
FAM91A1 |
157769 |
Q658Y4 |
0.63 |
ALDH1L2 |
160428 |
Q3SY69 |
0.63 |
SPATA5 |
166378 |
Q8NB90 |
0.63 |
TUBB2B |
347733 |
Q9BVA1 |
0.63 |
CTU2 |
348180 |
Q2VPK5 |
0.63 |
PRKCA |
5578 |
P17252 |
0.65 |
RHOA |
387 |
P61586 |
0.68 |
BID |
637 |
P55957 |
0.68 |
MAPK8 |
5599 |
P45983 |
0.68 |
CALM2 |
805 |
P62158 |
0.71 |
CALM3 |
808 |
P62158 |
0.71 |
RAP1A |
5906 |
P62834 |
0.71 |
EZR |
7430 |
P15311 |
0.78 |
MAP3K5 |
4217 |
Q99683 |
0.83 |
CFLAR |
8837 |
O15519 |
0.87 |
FAS |
355 |
P25445 |
0.88 |
CASP10 |
843 |
Q92851 |
0.88 |
BTK |
695 |
Q06187 |
0.52 |
CD47 |
961 |
Q08722 |
0.52 |
EGFR |
1956 |
P00533 |
0.55 |
BMX |
660 |
P51813 |
0.63 |
EEF1A1 |
1915 |
P68104 |
0.63 |
HNRNPC |
3183 |
P07910 |
0.63 |
PRKAG1 |
5571 |
P54619 |
0.63 |
RARA |
5914 |
P10276 |
0.63 |
TNF |
7124 |
P01375 |
0.63 |
YES1 |
7525 |
P07947 |
0.63 |
BAG6 |
7917 |
P46379 |
0.63 |
TCAP |
8557 |
O15273 |
0.63 |
TP63 |
8626 |
Q9H3D4 |
0.63 |
SQSTM1 |
8878 |
Q13501 |
0.63 |
MBD4 |
8930 |
O95243 |
0.63 |
BRE |
9577 |
Q9NXR7 |
0.63 |
FAIM2 |
23017 |
Q9BWQ8 |
0.63 |
UBA7 |
7318 |
P41226 |
0.65 |
ANK3 |
288 |
Q12955 |
0.67 |
FEM1B |
10116 |
Q9UK73 |
0.67 |
KRIT1 |
889 |
O00522 |
0.68 |
CAV1 |
857 |
Q03135 |
0.73 |
CASP8AP2 |
9994 |
Q9UKL3 |
0.73 |
FBF1 |
85302 |
Q8TES7 |
0.73 |
RIPK1 |
8737 |
Q13546 |
0.75 |
TNFSF13 |
8741 |
O75888 |
0.75 |
PML |
5371 |
P29590 |
0.76 |
TRADD |
8717 |
Q15628 |
0.76 |
HIPK3 |
10114 |
Q9H422 |
0.83 |
LCK |
3932 |
P06239 |
0.85 |
FYN |
2534 |
P06241 |
0.87 |
SUMO1 |
7341 |
P63165 |
0.89 |
PDCD6 |
10016 |
O75340 |
0.89 |
FASLG |
356 |
P48023 |
0.90 |
PTPN13 |
5783 |
Q12923 |
0.90 |
UBE2I |
7329 |
P63279 |
0.95 |
FAF1 |
11124 |
Q9UNN5 |
0.95 |
CASP8 |
841 |
Q14790 |
0.96 |
DAXX |
1616 |
Q9UER7 |
0.97 |
FADD |
8772 |
Q13158 |
0.97 |