Protein Description

Gene Symbol KRT13
Entrez ID 3860
Uniprot ID P13646
Description keratin 13, type I
Chromosomal Location chr17: 41,500,981-41,505,705
Ontology GO ID GO Term Definition Evidence

BP

GO:0007010

cytoskeleton organization

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures.

IDA

BP

GO:0009314

response to radiation

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electromagnetic radiation stimulus. Electromagnetic radiation is a propagating wave in space with electric and magnetic components. These components oscillate at right angles to each other and to the direction of propagation.

IEA

BP

GO:0043587

tongue morphogenesis

The process in which the anatomical structures of the tongue are generated and organized. The tongue is the movable, muscular organ on the floor of the mouth of most vertebrates, in man other mammals is the principal organ of taste, aids in the prehension of food, in swallowing, and in modifying the voice as in speech.

IEA

BP

GO:0071300

cellular response to retinoic acid

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a retinoic acid stimulus.

IEA

CC

GO:0005634

nucleus

A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

IDA

CC

GO:0045095

keratin filament

A filament composed of acidic and basic keratins (types I and II), typically expressed in epithelial cells. The keratins are the most diverse classes of IF proteins, with a large number of keratin isoforms being expressed. Each type of epithelium always expresses a characteristic combination of type I and type II keratins.

IDA

CC

GO:0045111

intermediate filament cytoskeleton

Cytoskeletal structure made from intermediate filaments, typically organized in the cytosol as an extended system that stretches from the nuclear envelope to the plasma membrane. Some intermediate filaments run parallel to the cell surface, while others traverse the cytosol; together they form an internal framework that helps support the shape and resilience of the cell.

IDA

CC

GO:0070062

extracellular exosome

A membrane-bounded vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.

IDA

MF

GO:0005198

structural molecule activity

The action of a molecule that contributes to the structural integrity of a complex or assembly within or outside a cell.

IEA

Domain ID Description

IPR001664

Intermediate filament protein

IPR002957

Keratin, type I

IPR018039

Intermediate filament protein, conserved site

No pathways found.

UMLS CUI UMLS Term

C1721005

Leukokeratosis, Hereditary Mucosal

Tissue Cell Type

cervix, uterine

squamous epithelial cells

esophagus

squamous epithelial cells

oral mucosa

squamous epithelial cells

No databases found.

Pubmed ID Author Year Title

23824412

Piltonen et al.

2013

Mesenchymal Stem/Progenitors and Other Endometrial Cell Types From Women With Polycystic Ovary Syndrome (PCOS) Display Inflammatory and Oncogenic Potential

Gene Symbol Entrez ID Uniprot ID Score

KRT7

3855

P08729

0.52

APC

324

P25054

0.63

MOS

4342

P00540

0.63

MYH1

4619

P12882

0.63

PSMB1

5689

P20618

0.63

PSMB2

5690

P49721

0.63

TMSB4X

7114

P62328

0.63

TSG101

7251

Q99816

0.63

EIF4E2

9470

O60573

0.63

CEP57

9702

Q86XR8

0.63

ABI2

10152

Q9NYB9

0.63

FARS2

10667

O95363

0.63

BLOC1S6

26258

Q9UL45

0.63

ABI3

51225

Q9P2A4

0.63

AMOTL2

51421

Q9Y2J4

0.63

KRT20

54474

P35900

0.63

CCHCR1

54535

Q8TD31

0.63

C1orf109

54955

Q9NX04

0.63

EXOSC5

56915

Q9NQT4

0.63

LSM2

57819

Q9Y333

0.63

ANKRD36BP1

84832

Q96IX9

0.63

FBF1

85302

Q8TES7

0.63

KLC4

89953

Q9NSK0

0.63

IFT20

90410

Q8IY31

0.63

KRT71

112802

Q3SY84

0.63

SGF29

112869

Q96ES7

0.63

C1orf216

127703

Q8TAB5

0.63

KLC3

147700

Q6P597

0.63

ALS2CR11

151254

Q53TS8

0.63

PPP1R18

170954

Q6NYC8

0.63

TXLNA

200081

P40222

0.63

CEP57L1

285753

Q8IYX8

0.63

KRT6C

286887

P48668

0.63

TRIM42

287015

Q8IWZ5

0.63

KRT79

338785

Q5XKE5

0.63

GOLGA8EP

390535

N/A

0.63

FAM127C

441518

Q17RB0

0.63

AES

166

Q08117

0.63

ATP5O

539

P48047

0.63

CCNC

892

P24863

0.63

ESR1

2099

P03372

0.63

GFAP

2670

P14136

0.63

KRT2

3849

P35908

0.63

KRT4

3851

P19013

0.63

KRT6A

3853

P02538

0.63

KRT6B

3854

P04259

0.63

KRT8

3856

P05787

0.63

NEDD8

4738

Q15843

0.63

RPS6KB2

6199

Q9UBS0

0.63

SHC1

6464

P29353

0.63

CUL5

8065

Q93034

0.63

CUL4B

8450

Q13620

0.63

CUL3

8452

Q13618

0.63

CUL2

8453

Q13617

0.63

CUL1

8454

Q13616

0.63

COPS5

10987

Q92905

0.63

GABARAP

11337

O95166

0.63

GABARAPL2

11345

P60520

0.63

GABARAPL1

23710

Q9H0R8

0.63

CAND1

55832

Q86VP6

0.63

MAP1LC3B

81631

Q9GZQ8

0.63

MAP1LC3A

84557

Q9H492

0.63

ALB

213

P02768

0.72