Gene Symbol | APOA1 |
Entrez ID | 335 |
Uniprot ID | P02647 |
Description | apolipoprotein A-I |
Chromosomal Location | chr11: 116,835,751-116,837,950 |
Ontology | GO ID | GO Term | Definition | Evidence |
---|---|---|---|---|
BP |
GO:0001523 |
retinoid metabolic process |
The chemical reactions and pathways involving retinoids, any member of a class of isoprenoids that contain or are derived from four prenyl groups linked head-to-tail. Retinoids include retinol and retinal and structurally similar natural derivatives or synthetic compounds, but need not have vitamin A activity. |
TAS |
BP |
GO:0001932 |
regulation of protein phosphorylation |
Any process that modulates the frequency, rate or extent of addition of phosphate groups into an amino acid in a protein. |
IEA |
BP |
GO:0001935 |
endothelial cell proliferation |
The multiplication or reproduction of endothelial cells, resulting in the expansion of a cell population. Endothelial cells are thin flattened cells which line the inside surfaces of body cavities, blood vessels, and lymph vessels, making up the endothelium. |
IEA |
BP |
GO:0002576 |
platelet degranulation |
The regulated exocytosis of secretory granules containing preformed mediators such as histamine and serotonin by a platelet. |
TAS |
BP |
GO:0002740 |
negative regulation of cytokine secretion involved in immune response |
Any process that stops, prevents, or reduces the frequency, rate, or extent of cytokine secretion contributing to an immune response. |
IDA |
BP |
GO:0006644 |
phospholipid metabolic process |
The chemical reactions and pathways involving phospholipids, any lipid containing phosphoric acid as a mono- or diester. |
IEA |
BP |
GO:0006656 |
phosphatidylcholine biosynthetic process |
The chemical reactions and pathways resulting in the formation of phosphatidylcholines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of choline. |
IDA |
BP |
GO:0006695 |
cholesterol biosynthetic process |
The chemical reactions and pathways resulting in the formation of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones. |
IBA |
BP |
GO:0006898 |
receptor-mediated endocytosis |
An endocytosis process in which cell surface receptors ensure specificity of transport. A specific receptor on the cell surface binds tightly to the extracellular macromolecule (the ligand) that it recognizes; the plasma-membrane region containing the receptor-ligand complex then undergoes endocytosis, forming a transport vesicle containing the receptor-ligand complex and excluding most other plasma-membrane proteins. Receptor-mediated endocytosis generally occurs via clathrin-coated pits and vesicles. |
TAS |
BP |
GO:0007186 |
G-protein coupled receptor signaling pathway |
A series of molecular signals that proceeds with an activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction, or for basal GPCR signaling the pathway begins with the receptor activating its G protein in the absence of an agonist, and ends with regulation of a downstream cellular process, e.g. transcription. The pathway can start from the plasma membrane, Golgi or nuclear membrane (PMID:24568158 and PMID:16902576). |
IDA |
BP |
GO:0007229 |
integrin-mediated signaling pathway |
A series of molecular signals initiated by the binding of extracellular ligand to an integrin on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription. |
IDA |
BP |
GO:0007584 |
response to nutrient |
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nutrient stimulus. |
IEA |
BP |
GO:0008203 |
cholesterol metabolic process |
The chemical reactions and pathways involving cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones. It is a component of the plasma membrane lipid bilayer and of plasma lipoproteins and can be found in all animal tissues. |
IMP |
BP |
GO:0008211 |
glucocorticoid metabolic process |
The chemical reactions and pathways involving glucocorticoids, hormonal C21 corticosteroids synthesized from cholesterol. Glucocorticoids act primarily on carbohydrate and protein metabolism, and have anti-inflammatory effects. |
IEA |
BP |
GO:0010804 |
negative regulation of tumor necrosis factor-mediated signaling pathway |
Any process that decreases the rate or extent of the tumor necrosis factor-mediated signaling pathway. The tumor necrosis factor-mediated signaling pathway is the series of molecular signals generated as a consequence of tumor necrosis factor binding to a cell surface receptor. |
IDA |
BP |
GO:0010873 |
positive regulation of cholesterol esterification |
Any process that increases the frequency, rate or extent of cholesterol esterification. Cholesterol esterification is the lipid modification process in which a sterol ester is formed by the combination of a carboxylic acid (often a fatty acid) and cholesterol. In the blood this process is associated with the conversion of free cholesterol into cholesteryl ester, which is then sequestered into the core of a lipoprotein particle. |
IDA |
BP |
GO:0010898 |
positive regulation of triglyceride catabolic process |
Any process that increases the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of triglyceride. |
IBA |
BP |
GO:0010903 |
negative regulation of very-low-density lipoprotein particle remodeling |
Any process that decreases the rate, frequency or extent of very-low-density lipoprotein particle remodeling. Very-low-density lipoprotein particle remodeling is the acquisition, loss or modification of a protein or lipid within a very-low-density lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase or lipoprotein lipase and the subsequent loss of free fatty acid. |
IDA |
BP |
GO:0014012 |
peripheral nervous system axon regeneration |
The regrowth of axons outside the central nervous system (outside the brain and spinal cord) following an axonal injury. |
IEA |
BP |
GO:0018158 |
protein oxidation |
The modification of a protein amino acid by oxidation. |
IDA |
BP |
GO:0018206 |
peptidyl-methionine modification |
The modification of peptidyl-methionine. |
IDA |
BP |
GO:0019433 |
triglyceride catabolic process |
The chemical reactions and pathways resulting in the breakdown of a triglyceride, any triester of glycerol. |
IBA |
BP |
GO:0019915 |
lipid storage |
The accumulation and maintenance in cells or tissues of lipids, compounds soluble in organic solvents but insoluble or sparingly soluble in aqueous solvents. Lipid reserves can be accumulated during early developmental stages for mobilization and utilization at later stages of development. |
IEA |
BP |
GO:0030300 |
regulation of intestinal cholesterol absorption |
Any process that modulates the frequency, rate or extent of absorption of cholesterol into the blood, and the exclusion of other sterols from absorption. |
IBA |
BP |
GO:0030301 |
cholesterol transport |
The directed movement of cholesterol, cholest-5-en-3-beta-ol, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. |
IDA |
BP |
GO:0030325 |
adrenal gland development |
The process whose specific outcome is the progression of the adrenal gland over time, from its formation to the mature structure. This gland can either be a discrete structure located bilaterally above each kidney, or a cluster of cells in the head kidney that perform the functions of the adrenal gland. In either case, this organ consists of two cells types, aminergic chromaffin cells and steroidogenic cortical cells. |
IEA |
BP |
GO:0031100 |
animal organ regeneration |
The regrowth of a lost or destroyed animal organ. |
IEA |
BP |
GO:0031102 |
neuron projection regeneration |
The regrowth of neuronal processes such as axons or dendrites in response to their loss or damage. |
IBA |
BP |
GO:0032489 |
regulation of Cdc42 protein signal transduction |
Any process that modulates the frequency, rate or extent of Cdc42 protein signal transduction. |
IDA |
BP |
GO:0033344 |
cholesterol efflux |
The directed movement of cholesterol, cholest-5-en-3-beta-ol, out of a cell or organelle. |
IDA|IMP |
BP |
GO:0033700 |
phospholipid efflux |
The directed movement of a phospholipid out of a cell or organelle. |
IDA |
BP |
GO:0034115 |
negative regulation of heterotypic cell-cell adhesion |
Any process that stops, prevents, or reduces the frequency, rate, or extent of heterotypic cell-cell adhesion. |
IDA |
BP |
GO:0034375 |
high-density lipoprotein particle remodeling |
The acquisition, loss or modification of a protein or lipid within a high-density lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase, with the subsequent loss of free fatty acid, and the transfer of cholesterol esters from LDL to a triglyceride-rich lipoprotein particle by cholesteryl ester transfer protein (CETP), with the simultaneous transfer of triglyceride to LDL. |
IC|IDA |
BP |
GO:0034380 |
high-density lipoprotein particle assembly |
The aggregation and arrangement of proteins and lipids to form a high-density lipoprotein particle. |
IDA |
BP |
GO:0034384 |
high-density lipoprotein particle clearance |
The process in which a high-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded. |
IC |
BP |
GO:0035025 |
positive regulation of Rho protein signal transduction |
Any process that activates or increases the frequency, rate or extent of Rho protein signal transduction. |
IDA |
BP |
GO:0042157 |
lipoprotein metabolic process |
The chemical reactions and pathways involving any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids. |
IBA|TAS |
BP |
GO:0042158 |
lipoprotein biosynthetic process |
The chemical reactions and pathways resulting in the formation of any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids. |
TAS |
BP |
GO:0042493 |
response to drug |
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a drug stimulus. A drug is a substance used in the diagnosis, treatment or prevention of a disease. |
IEA |
BP |
GO:0042632 |
cholesterol homeostasis |
Any process involved in the maintenance of an internal steady state of cholesterol within an organism or cell. |
IDA|IMP |
BP |
GO:0043534 |
blood vessel endothelial cell migration |
The orderly movement of an endothelial cell into the extracellular matrix in order to form new blood vessels during angiogenesis. |
IEA |
BP |
GO:0043627 |
response to estrogen |
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by an estrogen, C18 steroid hormones that can stimulate the development of female sexual characteristics. |
IEA |
BP |
GO:0043691 |
reverse cholesterol transport |
The directed movement of peripheral cell cholesterol, cholest-5-en-3-beta-ol, towards the liver for catabolism. |
IMP |
BP |
GO:0044267 |
cellular protein metabolic process |
The chemical reactions and pathways involving a specific protein, rather than of proteins in general, occurring at the level of an individual cell. Includes cellular protein modification. |
TAS |
BP |
GO:0045723 |
positive regulation of fatty acid biosynthetic process |
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of fatty acids. |
IBA |
BP |
GO:0050713 |
negative regulation of interleukin-1 beta secretion |
Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of interleukin-1 beta from a cell. |
IDA |
BP |
GO:0050728 |
negative regulation of inflammatory response |
Any process that stops, prevents, or reduces the frequency, rate or extent of the inflammatory response. |
IDA |
BP |
GO:0050821 |
protein stabilization |
Any process involved in maintaining the structure and integrity of a protein and preventing it from degradation or aggregation. |
IDA |
BP |
GO:0050919 |
negative chemotaxis |
The directed movement of a motile cell or organism towards a lower concentration of a chemical. |
IDA |
BP |
GO:0051006 |
positive regulation of lipoprotein lipase activity |
Any process that activates or increases the activity of the enzyme lipoprotein lipase. |
IBA |
BP |
GO:0051180 |
vitamin transport |
The directed movement of vitamins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A vitamin is one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body. |
IMP |
BP |
GO:0051345 |
positive regulation of hydrolase activity |
Any process that activates or increases the frequency, rate or extent of hydrolase activity, the catalysis of the hydrolysis of various bonds. |
IDA |
BP |
GO:0051496 |
positive regulation of stress fiber assembly |
Any process that activates or increases the frequency, rate or extent of the assembly of a stress fiber, a bundle of microfilaments and other proteins found in fibroblasts. |
IDA |
BP |
GO:0055085 |
transmembrane transport |
The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other |
TAS |
BP |
GO:0055091 |
phospholipid homeostasis |
Any process involved in the maintenance of an internal steady state of phospholipid within an organism or cell. |
IDA |
BP |
GO:0060192 |
negative regulation of lipase activity |
Any process that decreases the frequency, rate or extent of lipase activity, the hydrolysis of a lipid or phospholipid. |
IEA |
BP |
GO:0060354 |
negative regulation of cell adhesion molecule production |
Any process that decreases the rate, frequency or extent of cell adhesion molecule production. Cell adhesion molecule production is the appearance of a cell adhesion molecule as a result of its biosynthesis or a decrease in its catabolism. |
IDA |
BP |
GO:0060761 |
negative regulation of response to cytokine stimulus |
Any process that decreases the rate, frequency, or extent of a response to cytokine stimulus. |
IDA |
BP |
GO:0070328 |
triglyceride homeostasis |
Any process involved in the maintenance of an internal steady state of triglyceride within an organism or cell. |
IDA |
BP |
GO:0070508 |
cholesterol import |
The directed movement of cholesterol into a cell or organelle. |
IMP |
BP |
GO:1900026 |
positive regulation of substrate adhesion-dependent cell spreading |
Any process that activates or increases the frequency, rate or extent of substrate adhesion-dependent cell spreading. |
IDA |
CC |
GO:0005576 |
extracellular region |
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite. |
TAS |
CC |
GO:0005615 |
extracellular space |
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid. |
IDA|ISS |
CC |
GO:0005634 |
nucleus |
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
IEA |
CC |
GO:0005769 |
early endosome |
A membrane-bounded organelle that receives incoming material from primary endocytic vesicles that have been generated by clathrin-dependent and clathrin-independent endocytosis; vesicles fuse with the early endosome to deliver cargo for sorting into recycling or degradation pathways. |
TAS |
CC |
GO:0005788 |
endoplasmic reticulum lumen |
The volume enclosed by the membranes of the endoplasmic reticulum. |
TAS |
CC |
GO:0005829 |
cytosol |
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. |
TAS |
CC |
GO:0005886 |
plasma membrane |
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
TAS |
CC |
GO:0009986 |
cell surface |
The external part of the cell wall and/or plasma membrane. |
IEA |
CC |
GO:0030139 |
endocytic vesicle |
A membrane-bounded intracellular vesicle formed by invagination of the plasma membrane around an extracellular substance. Endocytic vesicles fuse with early endosomes to deliver the cargo for further sorting. |
IDA |
CC |
GO:0031410 |
cytoplasmic vesicle |
A vesicle found in the cytoplasm of a cell. |
IDA |
CC |
GO:0034361 |
very-low-density lipoprotein particle |
A triglyceride-rich lipoprotein particle that is typically composed of APOB100, APOE and APOCs and has a density of about 1.006 g/ml and a diameter of between 20-80 nm. It is found in blood and transports endogenous products (newly synthesized cholesterol and triglycerides) from the liver. |
IDA |
CC |
GO:0034364 |
high-density lipoprotein particle |
A lipoprotein particle with a high density (typically 1.063-1.21 g/ml) and a diameter of 5-10 nm that contains APOAs and may contain APOCs and APOE; found in blood and carries lipids from body tissues to the liver as part of the reverse cholesterol transport process. |
IDA |
CC |
GO:0034365 |
discoidal high-density lipoprotein particle |
A newly formed high-density lipoprotein particle; consists of a phospholipid bilayer surrounded by two or more APOA1 molecules. The discoidal HDL particle is formed when lipid-free or lipid-poor APOA1 acquires phospholipids and unesterified cholesterol from either cell membranes or triglyceride-rich lipoproteins (undergoing lipolysis by lipoprotein lipase). |
IEA |
CC |
GO:0034366 |
spherical high-density lipoprotein particle |
A mature high-density lipoprotein (HDL) particle, converted from discoidal HDL particles following the esterification of cholesterol in the particle by phosphatidylcholine-sterol O-acyltransferase (lecithin cholesterol acyltransferase; LCAT). |
IDA |
CC |
GO:0034774 |
secretory granule lumen |
The volume enclosed by the membrane of a secretory granule. |
TAS |
CC |
GO:0042627 |
chylomicron |
A large lipoprotein particle (diameter 75-1200 nm) composed of a central core of triglycerides and cholesterol surrounded by a protein-phospholipid coating. The proteins include one molecule of apolipoprotein B-48 and may include a variety of apolipoproteins, including APOAs, APOCs and APOE. Chylomicrons are found in blood or lymph and carry lipids from the intestines into other body tissues. |
IBA |
CC |
GO:0070062 |
extracellular exosome |
A membrane-bounded vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm. |
IDA |
CC |
GO:0071682 |
endocytic vesicle lumen |
The volume enclosed by the membrane of an endocytic vesicle. |
TAS |
CC |
GO:0072562 |
blood microparticle |
A phospholipid microvesicle that is derived from any of several cell types, such as platelets, blood cells, endothelial cells, or others, and contains membrane receptors as well as other proteins characteristic of the parental cell. Microparticles are heterogeneous in size, and are characterized as microvesicles free of nucleic acids. |
IDA |
CC |
GO:1903561 |
extracellular vesicle |
Any vesicle that is part of the extracellular region. |
IDA |
MF |
GO:0001540 |
beta-amyloid binding |
Interacting selectively and non-covalently with beta-amyloid peptide/protein and/or its precursor. |
IDA |
MF |
GO:0005515 |
protein binding |
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules). |
IPI |
MF |
GO:0005543 |
phospholipid binding |
Interacting selectively and non-covalently with phospholipids, a class of lipids containing phosphoric acid as a mono- or diester. |
IDA |
MF |
GO:0005548 |
phospholipid transporter activity |
Enables the directed movement of phospholipids into, out of or within a cell, or between cells. Phospholipids are a class of lipids containing phosphoric acid as a mono- or diester. |
IEA |
MF |
GO:0008035 |
high-density lipoprotein particle binding |
Interacting selectively and non-covalently with high-density lipoprotein particle, a lipoprotein particle with a high density (typically 1.063-1.21 g/ml) and a diameter of 5-10 nm that contains APOAs and may contain APOCs and APOE. |
IEA |
MF |
GO:0015485 |
cholesterol binding |
Interacting selectively and non-covalently with cholesterol (cholest-5-en-3-beta-ol); the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones. |
IDA |
MF |
GO:0017127 |
cholesterol transporter activity |
Enables the directed movement of cholesterol into, out of or within a cell, or between cells. Cholesterol is the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones. |
IDA|IMP |
MF |
GO:0019899 |
enzyme binding |
Interacting selectively and non-covalently with any enzyme. |
IPI |
MF |
GO:0031210 |
phosphatidylcholine binding |
Interacting selectively and non-covalently with phosphatidylcholine, a class of glycophospholipids in which a phosphatidyl group is esterified to the hydroxyl group of choline. |
IBA |
MF |
GO:0034190 |
apolipoprotein receptor binding |
Interacting selectively and non-covalently with an apolipoprotein receptor. |
IPI |
MF |
GO:0034191 |
apolipoprotein A-I receptor binding |
Interacting selectively and non-covalently with an apolipoprotein A-I receptor. |
IPI |
MF |
GO:0042802 |
identical protein binding |
Interacting selectively and non-covalently with an identical protein or proteins. |
IPI |
MF |
GO:0045499 |
chemorepellent activity |
Providing the environmental signal that initiates the directed movement of a motile cell or organism towards a lower concentration of that signal. |
IDA |
MF |
GO:0055102 |
lipase inhibitor activity |
Stops, prevents or reduces the activity of a lipase, an enzyme that catalyzes of the hydrolysis of a lipid. |
IEA |
MF |
GO:0060228 |
phosphatidylcholine-sterol O-acyltransferase activator activity |
Increases the activity of phosphatidylcholine-sterol O-acyltransferase, an enzyme that converts cholesterol and phosphatidylcholine (lecithins) to cholesteryl esters and lyso-phosphatidylcholines. |
IDA |
MF |
GO:0070653 |
high-density lipoprotein particle receptor binding |
Interacting selectively and non-covalently with a high-density lipoprotein receptor. |
IPI |
Domain ID | Description |
---|---|
IPR000074 |
Apolipoprotein A/E |
Pathway ID | Pathway Term | Pathway Source |
---|---|---|
hsa03320 |
PPAR signaling pathway |
KEGG |
hsa04975 |
Fat digestion and absorption |
KEGG |
hsa04977 |
Vitamin digestion and absorption |
KEGG |
hsa05143 |
African trypanosomiasis |
KEGG |
WP1533 |
Vitamin B12 Metabolism |
WikiPathways |
WP15 |
Selenium Micronutrient Network |
WikiPathways |
WP430 |
Statin Pathway |
WikiPathways |
WP2878 |
PPAR Alpha Pathway |
WikiPathways |
WP3942 |
PPAR signaling pathway |
WikiPathways |
WP176 |
Folate Metabolism |
WikiPathways |
WP3601 |
Composition of Lipid Particles |
WikiPathways |
h_pparaPathway |
Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha) |
BioCarta |
UMLS CUI | UMLS Term |
---|---|
C0001418 |
Adenocarcinoma |
C0003130 |
Anoxia |
C0004943 |
Behcet Syndrome |
C0011065 |
Cessation Of Life |
C0011609 |
Drug Eruptions |
C0013604 |
Edema |
C0017665 |
Membranous Glomerulonephritis |
C0019693 |
HIV Infections |
C0020538 |
Hypertensive Disease |
C0021368 |
Inflammation |
C0024121 |
Lung Neoplasms |
C0038356 |
Stomach Neoplasms |
C0038454 |
Cerebrovascular Accident |
C0242488 |
Acute Lung Injury |
C0473527 |
Hypoalphalipoproteinemias |
C0853897 |
Diabetic Cardiomyopathies |
C0860207 |
Drug-Induced Liver Injury |
C1704429 |
Hypoalphalipoproteinemia, Familial |
C2239176 |
Liver Carcinoma |
Database Name |
---|
DisGeNET |
DISEASES |
DGA |
Pubmed ID | Author | Year | Title |
---|---|---|---|
15308691 |
Jansen et al. |
2004 |
Abnormal Gene Expression Profiles in Human Ovaries from Polycystic Ovary Syndrome Patients |
17557764 |
Ma et al. |
2007 |
Proteomic analysis of human ovaries from normal and polycystic ovarian syndrome |
18156650 |
Corton et al. |
2008 |
Proteomic analysis of human omental adipose tissue in the polycystic ovary syndrome using two-dimensional difference gel electrophoresis and mass spectrometry |
20426491 |
Choi et al. |
2010 |
The Apolipoprotein A-I Level Is Downregulated in the Granulosa Cells of Patients with Polycystic Ovary Syndrome and Affects Steroidogenesis |
22935150 |
Dai & Lu |
2012 |
Different protein expression patterns associated with polycystic ovary syndrome in human follicular fluid during controlled ovarian hyperstimulation |
25393639 |
Ambekar et al. |
2014 |
Proteomics of follicular fluid from women with polycystic ovary syndrome suggests molecular defects in follicular development |
Gene Symbol | Entrez ID | Uniprot ID | Score |
---|---|---|---|
RXRG |
6258 |
P48443 |
0.00 |
APOD |
347 |
P05090 |
0.49 |
DGAT1 |
8694 |
O75907 |
0.49 |
HPR |
3250 |
P00739 |
0.52 |
APOF |
319 |
Q13790 |
0.58 |
ATP5B |
506 |
P06576 |
0.62 |
CETP |
1071 |
P11597 |
0.62 |
CFHR1 |
100293069 |
Q03591 |
0.62 |
AKT2 |
208 |
P31751 |
0.63 |
FBLN1 |
2192 |
P23142 |
0.63 |
PCMT1 |
5110 |
P22061 |
0.63 |
PDE1A |
5136 |
P54750 |
0.63 |
SPP1 |
6696 |
P10451 |
0.63 |
VCP |
7415 |
P55072 |
0.63 |
BRAP |
8315 |
Q7Z569 |
0.63 |
TNFRSF10C |
8794 |
O14798 |
0.63 |
TOMM20 |
9804 |
Q15388 |
0.63 |
IGKV2-40 |
28916 |
N/A |
0.63 |
ZNRD1 |
30834 |
Q9P1U0 |
0.63 |
CMTM5 |
116173 |
Q96DZ9 |
0.63 |
ERVK-10 |
100616101 |
P10266 |
0.63 |
KV201_HUMAN |
N/A |
P01614 |
0.63 |
APOA2 |
336 |
P02652 |
0.66 |
APOC3 |
345 |
P02656 |
0.72 |
C1QA |
712 |
P02745 |
0.72 |
C1QC |
714 |
P02747 |
0.72 |
CLU |
1191 |
P10909 |
0.72 |
CP |
1356 |
P00450 |
0.72 |
CTSL |
1514 |
P07711 |
0.72 |
DNTT |
1791 |
P04053 |
0.72 |
FN1 |
2335 |
P02751 |
0.72 |
HBA1 HBA2 |
3039 |
P69905 |
0.72 |
IGKC |
3514 |
P01834 |
0.72 |
KRT1 |
3848 |
P04264 |
0.72 |
KRT9 |
3857 |
P35527 |
0.72 |
KRT16 |
3868 |
P08779 |
0.72 |
PDE4B |
5142 |
Q07343 |
0.72 |
QDPR |
5860 |
P09417 |
0.72 |
SAFB2 |
9667 |
Q14151 |
0.72 |
SMPDL3A |
10924 |
Q92484 |
0.72 |
LECT1 |
11061 |
O75829 |
0.72 |
NLRP1 |
22861 |
Q9C000 |
0.72 |
SETX |
23064 |
Q7Z333 |
0.72 |
RRP1B |
23076 |
Q14684 |
0.72 |
ABCA6 |
23460 |
Q8N139 |
0.72 |
FAM169A |
26049 |
Q9Y6X4 |
0.72 |
SERTAD3 |
29946 |
Q9UJW9 |
0.72 |
MOCOS |
55034 |
Q96EN8 |
0.72 |
ROBO3 |
64221 |
Q96MS0 |
0.72 |
TNS3 |
64759 |
Q68CZ2 |
0.72 |
SPEF2 |
79925 |
Q9C093 |
0.72 |
TXNDC2 |
84203 |
Q86VQ3 |
0.72 |
PTPN5 |
84867 |
P54829 |
0.72 |
FAM83C |
128876 |
Q9BQN1 |
0.72 |
KIAA0754 |
643314 |
O94854 |
0.72 |
LBP |
3929 |
P18428 |
0.73 |
MAP7D1 |
55700 |
Q3KQU3 |
0.73 |
APOB |
338 |
P04114 |
0.75 |
ABCA1 |
19 |
O95477 |
0.78 |
FGA |
2243 |
P02671 |
0.83 |
TTR |
7276 |
P02766 |
0.83 |
APOC1 |
341 |
P02654 |
0.86 |
PLTP |
5360 |
P55058 |
0.86 |
APP |
351 |
P05067 |
0.88 |
APOA1 |
335 |
P02647 |
0.90 |
PON1 |
5444 |
P27169 |
0.52 |
ABCA13 |
154664 |
Q86UQ4 |
0.56 |
ALDH2 |
217 |
P05091 |
0.63 |
ATP4A |
495 |
P20648 |
0.63 |
IGHA1 |
3493 |
P01876 |
0.63 |
IGHG1 |
3500 |
P01857 |
0.63 |
IGHM |
3507 |
P01871 |
0.63 |
JAK3 |
3718 |
P52333 |
0.63 |
MAPK6 |
5597 |
Q16659 |
0.63 |
TF |
7018 |
P02787 |
0.63 |
DDX19B |
11269 |
Q9UMR2 |
0.63 |
UCHL5 |
51377 |
Q9Y5K5 |
0.63 |
VKORC1 |
79001 |
Q9BQB6 |
0.63 |
NAXE |
128240 |
Q8NCW5 |
0.63 |
ZNF558 |
148156 |
Q96NG5 |
0.63 |
GDPD1 |
284161 |
Q8N9F7 |
0.63 |
CLEC4G |
339390 |
Q6UXB4 |
0.63 |
APOL1 |
8542 |
O14791 |
0.68 |
ALB |
213 |
P02768 |
0.72 |
CD40LG |
959 |
P29965 |
0.72 |
HP |
3240 |
P00738 |
0.72 |
MIS12 |
79003 |
Q9H081 |
0.72 |
GPLD1 |
2822 |
P80108 |
0.79 |
SCARB1 |
949 |
Q8WTV0 |
0.81 |
LCAT |
3931 |
P04180 |
0.90 |