Protein Description

Gene Symbol ILF3
Entrez ID 3609
Uniprot ID Q12906
Description interleukin enhancer binding factor 3
Chromosomal Location chr19: 10,654,261-10,692,417
Ontology GO ID GO Term Definition Evidence

BP

GO:0006351

transcription, DNA-templated

The cellular synthesis of RNA on a template of DNA.

IEA

BP

GO:0006468

protein phosphorylation

The process of introducing a phosphate group on to a protein.

IDA

BP

GO:0017148

negative regulation of translation

Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA.

ISS

BP

GO:0045071

negative regulation of viral genome replication

Any process that stops, prevents, or reduces the frequency, rate or extent of viral genome replication.

ISS

BP

GO:0045892

negative regulation of transcription, DNA-templated

Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.

IDA

BP

GO:0045893

positive regulation of transcription, DNA-templated

Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.

IDA

BP

GO:0051607

defense response to virus

Reactions triggered in response to the presence of a virus that act to protect the cell or organism.

IEA

CC

GO:0005634

nucleus

A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

IDA|NAS

CC

GO:0005654

nucleoplasm

That part of the nuclear content other than the chromosomes or the nucleolus.

IDA

CC

GO:0005730

nucleolus

A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.

IDA

CC

GO:0005737

cytoplasm

All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

IDA

CC

GO:0005739

mitochondrion

A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.

IDA

CC

GO:0016020

membrane

A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.

IDA

CC

GO:0030529

intracellular ribonucleoprotein complex

An intracellular macromolecular complex containing both protein and RNA molecules.

IDA

MF

GO:0003677

DNA binding

Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).

IDA

MF

GO:0003723

RNA binding

Interacting selectively and non-covalently with an RNA molecule or a portion thereof.

NAS

MF

GO:0003725

double-stranded RNA binding

Interacting selectively and non-covalently with double-stranded RNA.

IDA

MF

GO:0005515

protein binding

Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).

IPI

MF

GO:0044822

poly(A) RNA binding

Interacting non-covalently with a poly(A) RNA, a RNA molecule which has a tail of adenine bases.

IDA

Domain ID Description

IPR006561

DZF domain

IPR014720

Double-stranded RNA-binding domain

IPR033099

Interleukin enhancer-binding factor 3

No pathways found.

No diseases found.

Tissue Cell Type

adrenal gland

glandular cells

appendix

glandular cells

appendix

lymphoid tissue

bone marrow

hematopoietic cells

caudate

glial cells

caudate

neuronal cells

cerebellum

cells in granular layer

cerebellum

cells in molecular layer

cerebellum

Purkinje cells

cerebral cortex

endothelial cells

cerebral cortex

glial cells

cerebral cortex

neuronal cells

cervix, uterine

glandular cells

cervix, uterine

squamous epithelial cells

colon

endothelial cells

colon

glandular cells

duodenum

glandular cells

endometrium

cells in endometrial stroma

endometrium

glandular cells

epididymis

glandular cells

esophagus

squamous epithelial cells

fallopian tube

glandular cells

gallbladder

glandular cells

heart muscle

myocytes

hippocampus

glial cells

hippocampus

neuronal cells

kidney

cells in glomeruli

kidney

cells in tubules

liver

bile duct cells

lung

macrophages

lung

pneumocytes

lymph node

germinal center cells

lymph node

non-germinal center cells

nasopharynx

respiratory epithelial cells

oral mucosa

squamous epithelial cells

ovary

follicle cells

ovary

ovarian stroma cells

pancreas

exocrine glandular cells

pancreas

islets of Langerhans

parathyroid gland

glandular cells

placenta

decidual cells

placenta

trophoblastic cells

prostate

glandular cells

rectum

glandular cells

salivary gland

glandular cells

seminal vesicle

glandular cells

skeletal muscle

myocytes

skin

fibroblasts

skin

keratinocytes

skin

Langerhans

skin

melanocytes

skin

epidermal cells

small intestine

glandular cells

smooth muscle

smooth muscle cells

soft tissue

adipocytes

soft tissue

chondrocytes

soft tissue

fibroblasts

soft tissue

peripheral nerve

spleen

cells in red pulp

spleen

cells in white pulp

stomach

glandular cells

testis

cells in seminiferous ducts

testis

Leydig cells

thyroid gland

glandular cells

tonsil

germinal center cells

tonsil

non-germinal center cells

tonsil

squamous epithelial cells

urinary bladder

urothelial cells

vagina

squamous epithelial cells

No databases found.

Pubmed ID Author Year Title

22617121

Ouandaogo et al.

2012

Differences in transcriptomic profiles of human cumulus cells isolated from oocytes at GV, MI and MII stages after in vivo andin vitro oocyte maturation

22951915

Haozi et al.

2012

Altered gene expression profile in cumulus cells of mature MII oocytes from patients with polycystic ovary syndrome

Gene Symbol Entrez ID Uniprot ID Score

DHODH

1723

Q02127

0.49

STOM

2040

P27105

0.49

GAA

2548

P10253

0.49

IL7R

3575

P16871

0.49

JUP

3728

P14923

0.49

KRT17

3872

Q04695

0.49

LAMP1

3916

P11279

0.49

LETM1

3954

O95202

0.49

LMNB1

4001

P20700

0.49

LMO7

4008

Q8WWI1

0.49

MOV10

4343

Q9HCE1

0.49

MYH10

4628

P35580

0.49

MYO1C

4641

O00159

0.49

MYO1E

4643

Q12965

0.49

NCL

4691

P19338

0.49

NDUFA2

4695

O43678

0.49

NDUFB9

4715

Q9Y6M9

0.49

NDUFV1

4723

P49821

0.49

NDUFS6

4726

O75380

0.49

NDUFV3

4731

P56181

0.49

RPL10A

4736

P62906

0.49

OPA1

4976

O60313

0.49

PC

5091

P11498

0.49

PLP2

5355

Q04941

0.49

POLR2A

5430

P24928

0.49

PRPH

5630

P41219

0.49

PTPN1

5770

P18031

0.49

ALDH18A1

5832

P54886

0.49

RAB2A

5862

P61019

0.49

RALA

5898

P11233

0.49

RAP1A

5906

P62834

0.49

RCN1

5954

Q15293

0.49

RCN2

5955

Q14257

0.49

RPL4

6124

P36578

0.49

RPL5

6125

P46777

0.49

RPL6

6128

Q02878

0.49

RPL7

6129

P18124

0.49

RPL7A

6130

P62424

0.49

RPL8

6132

P62917

0.49

RPL11

6135

P62913

0.49

RPL12

6136

P30050

0.49

RPL13

6137

P26373

0.49

RPL15

6138

P61313

0.49

RPL17

6139

P18621

0.49

RPL18

6141

Q07020

0.49

RPL19

6143

P84098

0.49

RPL21

6144

P46778

0.49

RPL22

6146

P35268

0.49

MRPL23

6150

Q16540

0.49

RPL24

6152

P83731

0.49

RPL27

6155

P61353

0.49

RPL29

6159

P47914

0.49

RPL31

6160

P62899

0.49

RPL32

6161

P62910

0.49

RPL37A

6168

P61513

0.49

MRPL12

6182

P52815

0.49

RPN1

6184

P04843

0.49

RPN2

6185

P04844

0.49

RPS3

6188

P23396

0.49

RPS3A

6189

P61247

0.49

RPS4X

6191

P62701

0.49

RPS6

6194

P62753

0.49

RPS8

6202

P62241

0.49

RPS13

6207

P62277

0.49

RPS14

6208

P62263

0.49

RPS15A

6210

P62244

0.49

RPS16

6217

P62249

0.49

RPS17

6218

P08708

0.49

RPS20

6224

P60866

0.49

RPS23

6228

P62266

0.49

RPS24

6229

P62847

0.49

RPS25

6230

P62851

0.49

RPS26

6231

P62854

0.49

RPS28

6234

P62857

0.49

RRBP1

6238

Q9P2E9

0.49

SFPQ

6421

P23246

0.49

SRSF3

6428

P84103

0.49

SRSF5

6430

Q13243

0.49

TRA2B

6434

P62995

0.49

SLC12A4

6560

Q9UP95

0.49

SNCG

6623

O76070

0.49

SNRNP70

6625

P08621

0.49

SON

6651

P18583

0.49

SSBP1

6742

Q04837

0.49

SSR1

6745

P43307

0.49

SSR4

6748

P51571

0.49

VAMP2

6844

P63027

0.49

TMPO

7112

P42166

0.49

TPM4

7171

P67936

0.49

TUBA4A

7277

P68366

0.49

UQCRC1

7384

P31930

0.49

UQCRH

7388

P07919

0.49

VTN

7448

P04004

0.49

PICALM

8301

Q13492

0.49

DHX16

8449

O60231

0.49

PLPP1

8611

O14494

0.49

RAB11A

8766

P62491

0.49

RPL14

9045

P50914

0.49

SART1

9092

O43290

0.49

RPL23

9349

P62829

0.49

PPT2

9374

Q9UMR5

0.49

RBM39

9584

Q14498

0.49

PDIA4

9601

P13667

0.49

SPCS2

9789

Q15005

0.49

NUP58

9818

Q9BVL2

0.49

PTBP3

9991

O95758

0.49

LRPPRC

10128

P42704

0.49

SLC25A17

10478

O43808

0.49

PGRMC1

10857

O00264

0.49

RNPS1

10921

Q15287

0.49

RAB31

11031

Q13636

0.49

EMC1

23065

Q8N766

0.49

MRPS27

23107

Q92552

0.49

NOMO1

23420

Q15155

0.49

SF3B1

23451

O75533

0.49

SRRM2

23524

Q9UQ35

0.49

TXN2

25828

Q99757

0.49

PTCD1

26024

O75127

0.49

SENP3

26168

Q9H4L4

0.49

LSM3

27258

P62310

0.49

LAMTOR2

28956

Q9Y2Q5

0.49

MRPL42

28977

Q9Y6G3

0.49

MRPL15

29088

Q9P015

0.49

RPS27L

51065

Q71UM5

0.49

MRPL4

51073

Q9BYD3

0.49

RAB14

51552

P61106

0.49

SF3B6

51639

Q9Y3B4

0.49

MRPL39

54148

Q9NYK5

0.49

SARS2

54938

Q9NP81

0.49

MRPL20

55052

Q9BYC9

0.49

MRPS10

55173

P82664

0.49

RMDN3

55177

Q96TC7

0.49

LRRC59

55379

Q96AG4

0.49

IARS2

55699

Q9NSE4

0.49

NCLN

56926

Q969V3

0.49

MFF

56947

Q9GZY8

0.49

TOMM22

56993

Q9NS69

0.49

RTN4

57142

Q9NQC3

0.49

SERINC1

57515

Q9NRX5

0.49

LSM2

57819

Q9Y333

0.49

MRPS35

60488

P82673

0.49

MRPL17

63875

Q9NRX2

0.49

MRPS14

63931

O60783

0.49

NUCKS1

64710

Q9H1E3

0.49

MRPS9

64965

P82933

0.49

MRPS5

64969

P82675

0.49

MRPL41

64975

Q8IXM3

0.49

MRPL40

64976

Q9NQ50

0.49

MRPL38

64978

Q96DV4

0.49

MRPL32

64983

Q9BYC8

0.49

MRPL11

65003

Q9Y3B7

0.49

MRPL9

65005

Q9BYD2

0.49

MRPL1

65008

Q9BYD6

0.49

MRPL44

65080

Q9H9J2

0.49

LPCAT1

79888

Q8NF37

0.49

PYROXD1

79912

Q8WU10

0.49

PTDSS2

81490

Q9BVG9

0.49

TRIM56

81844

Q9BRZ2

0.49

SLIRP

81892

Q9GZT3

0.49

SF3B5

83443

Q9BWJ5

0.49

MRPL45

84311

Q9BRJ2

0.49

SFXN1

94081

Q9H9B4

0.49

PRKCDBP

112464

Q969G5

0.49

MRPL10

124995

Q7Z7H8

0.49

MRPL55

128308

Q7Z7F7

0.49

NUP35

129401

Q8NFH5

0.49

CHCHD4

131474

Q8N4Q1

0.49

OCIAD2

132299

Q56VL3

0.49

NFXL1

152518

Q6ZNB6

0.49

QSOX2

169714

Q6ZRP7

0.49

RPLP0P6

220717

Q8NHW5

0.49

PTRF

284119

Q6NZI2

0.49

ZNF326

284695

Q5BKZ1

0.49

RPL9; RPL9P7; RPL9P8; RPL9P9

6133

P32969

0.49

ACTG1

71

P63261

0.63

EEF1A1

1915

P68104

0.63

HIST1H1E

3008

P10412

0.63

HNRNPH2

3188

P55795

0.63

HSP90AA1

3320

P07900

0.63

IGKC

3514

P01834

0.63

KIF5C

3800

O60282

0.63

MT-TA

4553

N/A

0.63

RMRP

6023

N/A

0.63

RPL10

6134

P27635

0.63

VEGFA

7422

P15692

0.63

RNF113A

7737

O15541

0.63

HIST2H2BE

8349

Q16778

0.63

NXF1

10482

Q9UBU9

0.63

IGF2BP2

10644

Q9Y6M1

0.63

RBPMS

11030

Q93062

0.63

SNORD50A

26799

N/A

0.63

RNU5A-1

26831

N/A

0.63

RNU5B-1

26832

N/A

0.63

RNU2-4P

26853

N/A

0.63

XAB2

56949

Q9HCS7

0.63

ELOVL7

79993

A1L3X0

0.63

PCBD2

84105

Q9H0N5

0.63

ZNF830

91603

Q96NB3

0.63

UNC45B

146862

Q8IWX7

0.63

KIAA0825

285600

Q8IV33

0.63

MALAT1

378938

Q9UHZ2

0.63

SNORD95

619570

N/A

0.63

SNORD10

652966

N/A

0.63

SCARNA22

677770

N/A

0.63

SNORA2C

677815

N/A

0.63

SNORA71D

677840

N/A

0.63

SNORD1C

677850

N/A

0.63

SNORD50B

692088

N/A

0.63

SNORD19

692089

N/A

0.63

SNORA57

692158

N/A

0.63

SNORD88C

692204

N/A

0.63

SNORD3C

780853

N/A

0.63

SNORD116-1

100033413

N/A

0.63

SNORD116-18

100033430

N/A

0.63

SNORD116-22

100033433

N/A

0.63

SNORD116-24

100033435

N/A

0.63

SNORD116-29

100033821

N/A

0.63

HIST1H2AG; HIST1H2AI; HIST1H2AK; HIST1H2AL; HIST1H2AM

8329

P0C0S8

0.63

SMN1; SMN2

6606

Q16637

0.67

HNRNPC

3183

P07910

0.72

MDFI

4188

Q99750

0.73

RPL3

6122

P39023

0.73

RPL18A

6142

Q02543

0.73

RPL23A

6147

P62750

0.73

RPS2

6187

P15880

0.73

PHB2

11331

Q99623

0.73

PABPC1

26986

P11940

0.73

KRTAP4-12

83755

Q9BQ66

0.73

PLSCR1

5359

O15162

0.74

FUS

2521

P35637

0.87

DHX9

1660

Q08211

0.88

EIF2AK2

5610

P19525

0.90

XPO5

57510

Q9HAV4

0.90

ILF2

3608

Q12905

0.94

PRMT1

3276

Q99873

0.97

HNRNPK

3190

P61978

0.49

HSPA5

3309

P11021

0.49

HNRNPR

10236

O43390

0.49

SYNCRIP

10492

O60506

0.49

DHX30

22907

Q7L2E3

0.49

GRB2

2885

P62993

0.56

APEX1

328

P27695

0.63

BIRC2

329

Q13490

0.63

BMI1

648

P35226

0.63

CDK2

1017

P24941

0.63

CRY1

1407

Q16526

0.63

CSF2

1437

P04141

0.63

DDX3X

1654

O00571

0.63

DDX6

1656

P26196

0.63

EGFR

1956

P00533

0.63

EZH2

2146

Q15910

0.63

NR5A2

2494

O00482

0.63

XRCC6

2547

P12956

0.63

GDF9

2661

O60383

0.63

GRK5

2869

P34947

0.63

ICAM1

3383

P05362

0.63

ITGA4

3676

P13612

0.63

JUN

3725

P05412

0.63

MAGEA11

4110

P43364

0.63

MCM2

4171

P49736

0.63

NEDD8

4738

Q15843

0.63

NTRK1

4914

P04629

0.63

MAPK13

5603

O15264

0.63

RNF2

6045

Q99496

0.63

RPA1

6117

P27694

0.63

RPA2

6118

P15927

0.63

RPA3

6119

P35244

0.63

SNRPC

6631

P09234

0.63

AURKA

6790

O14965

0.63

TADA2A

6871

O75478

0.63

SUMO1

7341

P63165

0.63

VHL

7428

P40337

0.63

WHSC1

7468

O96028

0.63

SF1

7536

Q15637

0.63

CUL5

8065

Q93034

0.63

PABPN1

8106

Q86U42

0.63

SF3A2

8175

Q15428

0.63

UBL4A

8266

P11441

0.63

HIST1H3A

8350

P68431

0.63

CUL3

8452

Q13618

0.63

CUL2

8453

Q13617

0.63

CUL1

8454

Q13616

0.63

RAE1

8480

P78406

0.63

EED

8726

O75530

0.63

BAG2

9532

O95816

0.63

KIAA0101

9768

Q15004

0.63

CUL7

9820

Q14999

0.63

HDAC5

10014

Q9UQL6

0.63

HUWE1

10075

Q7Z6Z7

0.63

RBM5

10181

P52756

0.63

NOP56

10528

O00567

0.63

UBD

10537

O15205

0.63

IVNS1ABP

10625

Q9Y6Y0

0.63

COPS5

10987

Q92905

0.63

GABARAP

11337

O95166

0.63

GABARAPL2

11345

P60520

0.63

SNW1

22938

Q13573

0.63

UNC13A

23025

Q9UPW8

0.63

OBSL1

23363

O75147

0.63

LARP1

23367

Q6PKG0

0.63

TARDBP

23435

Q13148

0.63

CBX6

23466

O95503

0.63

SUZ12

23512

Q15022

0.63

GABARAPL1

23710

Q9H0R8

0.63

FBXO6

26270

Q9NRD1

0.63

AGO1

26523

Q9UL18

0.63

AGO2

27161

Q9UKV8

0.63

DCUN1D1

54165

Q96GG9

0.63

DGCR8

54487

Q8WYQ5

0.63

LGR4

55366

Q9BXB1

0.63

RIOK2

55781

Q9BVS4

0.63

CAND1

55832

Q86VP6

0.63

SMARCAD1

56916

Q9H4L7

0.63

MAP1LC3B

81631

Q9GZQ8

0.63

EIF2A

83939

Q9BY44

0.63

CCDC8

83987

Q9H0W5

0.63

MAP1LC3A

84557

Q9H492

0.63

LNX1

84708

Q8TBB1

0.63

IGSF8

93185

Q969P0

0.63

EP300

2033

Q09472

0.68

ERG

2078

P11308

0.68

HNRNPL

3191

P14866

0.68

YY1

7528

P25490

0.68

ABL1

25

P00519

0.72

ARRB2

409

P32121

0.72

FN1

2335

P02751

0.72

HNRNPU

3192

Q00839

0.72

IFIT2

3433

P09913

0.72

IFIT3

3437

O14879

0.72

ILK

3611

Q13418

0.72

MAGOH

4116

P61326

0.72

PPP1CB

5500

P62140

0.72

PPP1CC

5501

P36873

0.72

SNCA

6622

P37840

0.72

SRPK1

6732

Q96SB4

0.72

TNK1

8711

Q13470

0.72

EIF4A3

9775

P38919

0.72

MATR3

9782

P43243

0.72

SGK2

10110

Q9HBY8

0.72

RAD50

10111

Q92878

0.72

RRP1B

23076

Q14684

0.72

RPAP1

26015

Q9BWH6

0.72

MPHOSPH8

54737

Q99549

0.72

MEPCE

56257

Q7L2J0

0.72

CBX8

57332

Q9HC52

0.72

KHDRBS2

202559

Q5VWX1

0.72

MDM2

4193

Q00987

0.73

SUMO3

6612

P55854

0.73

SUMO2

6613

P61956

0.73

STAU1

6780

O95793

0.73

TRIP6

7205

Q15654

0.73

SF3B4

10262

Q15427

0.73

NDRG1

10397

Q92597

0.73

FBXW11

23291

Q9UKB1

0.73

ZNF346

23567

Q9UL40

0.75

ESR1

2099

P03372

0.78

MCM5

4174

P33992

0.82

MCM7

4176

P33993

0.82

YBX1

4904

P67809

0.82

VCAM1

7412

P19320

0.82

PRKDC

5591

P78527

0.85

HNRNPA1

3178

P09651

0.87