Protein Description

Gene Symbol ILF2
Entrez ID 3608
Uniprot ID Q12905
Description interleukin enhancer binding factor 2
Chromosomal Location chr1: 153,661,788-153,671,048
Ontology GO ID GO Term Definition Evidence

BP

GO:0006351

transcription, DNA-templated

The cellular synthesis of RNA on a template of DNA.

IDA

BP

GO:0006955

immune response

Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat.

IEA

BP

GO:0045893

positive regulation of transcription, DNA-templated

Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.

IDA

CC

GO:0005634

nucleus

A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

IDA

CC

GO:0005654

nucleoplasm

That part of the nuclear content other than the chromosomes or the nucleolus.

IDA

CC

GO:0005730

nucleolus

A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.

IDA

CC

GO:0005737

cytoplasm

All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

IEA

CC

GO:0016020

membrane

A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.

IDA

CC

GO:0030529

intracellular ribonucleoprotein complex

An intracellular macromolecular complex containing both protein and RNA molecules.

IDA

MF

GO:0003677

DNA binding

Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).

IDA

MF

GO:0003725

double-stranded RNA binding

Interacting selectively and non-covalently with double-stranded RNA.

IDA

MF

GO:0005515

protein binding

Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).

IPI

MF

GO:0005524

ATP binding

Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.

IEA

MF

GO:0016740

transferase activity

Catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2.

IEA

MF

GO:0044822

poly(A) RNA binding

Interacting non-covalently with a poly(A) RNA, a RNA molecule which has a tail of adenine bases.

IDA

Domain ID Description

IPR006116

2-5-oligoadenylate synthetase, N-terminal

IPR006561

DZF domain

Pathway ID Pathway Term Pathway Source

WP23

B Cell Receptor Signaling Pathway

WikiPathways

UMLS CUI UMLS Term

C0019693

HIV Infections

Tissue Cell Type

adrenal gland

glandular cells

appendix

glandular cells

appendix

lymphoid tissue

bone marrow

hematopoietic cells

breast

adipocytes

breast

glandular cells

breast

myoepithelial cells

bronchus

respiratory epithelial cells

caudate

glial cells

caudate

neuronal cells

cerebellum

cells in granular layer

cerebellum

cells in molecular layer

cerebellum

Purkinje cells

cerebral cortex

endothelial cells

cerebral cortex

glial cells

cerebral cortex

neuronal cells

cervix, uterine

glandular cells

colon

endothelial cells

colon

glandular cells

colon

peripheral nerve/ganglion

duodenum

glandular cells

endometrium

cells in endometrial stroma

endometrium

glandular cells

epididymis

glandular cells

esophagus

squamous epithelial cells

fallopian tube

glandular cells

gallbladder

glandular cells

heart muscle

myocytes

hippocampus

glial cells

hippocampus

neuronal cells

kidney

cells in glomeruli

kidney

cells in tubules

liver

bile duct cells

lung

macrophages

lung

pneumocytes

lymph node

germinal center cells

lymph node

non-germinal center cells

nasopharynx

respiratory epithelial cells

oral mucosa

squamous epithelial cells

ovary

ovarian stroma cells

pancreas

exocrine glandular cells

pancreas

islets of Langerhans

placenta

decidual cells

placenta

trophoblastic cells

prostate

glandular cells

rectum

glandular cells

salivary gland

glandular cells

seminal vesicle

glandular cells

skeletal muscle

myocytes

skin

fibroblasts

skin

keratinocytes

skin

Langerhans

skin

melanocytes

skin

epidermal cells

small intestine

glandular cells

smooth muscle

smooth muscle cells

soft tissue

adipocytes

soft tissue

fibroblasts

soft tissue

peripheral nerve

spleen

cells in red pulp

spleen

cells in white pulp

stomach

glandular cells

testis

cells in seminiferous ducts

testis

Leydig cells

thyroid gland

glandular cells

tonsil

germinal center cells

tonsil

non-germinal center cells

tonsil

squamous epithelial cells

urinary bladder

urothelial cells

vagina

squamous epithelial cells

No databases found.

Pubmed ID Author Year Title

12734205

Wood et al.

2003

The Molecular Phenotype of Polycystic Ovary Syndrome (PCOS) Theca Cells and New Candidate PCOS Genes Defined by Microarray Analysis

23824412

Piltonen et al.

2013

Mesenchymal Stem/Progenitors and Other Endometrial Cell Types From Women With Polycystic Ovary Syndrome (PCOS) Display Inflammatory and Oncogenic Potential

Gene Symbol Entrez ID Uniprot ID Score

RHOB

388

P62745

0.49

DDOST

1650

P39656

0.49

IL7R

3575

P16871

0.49

JUP

3728

P14923

0.49

LAMP1

3916

P11279

0.49

LBR

3930

Q14739

0.49

MTR

4548

Q99707

0.49

PC

5091

P11498

0.49

ALDH18A1

5832

P54886

0.49

RANBP2

5903

P49792

0.49

RAP1B

5908

P61224

0.49

RCN1

5954

Q15293

0.49

RPL4

6124

P36578

0.49

RPL5

6125

P46777

0.49

RPL7

6129

P18124

0.49

RPL7A

6130

P62424

0.49

RPL8

6132

P62917

0.49

RPL10

6134

P27635

0.49

RPL11

6135

P62913

0.49

RPL17

6139

P18621

0.49

RPL18

6141

Q07020

0.49

RPL19

6143

P84098

0.49

RPL21

6144

P46778

0.49

RPL23A

6147

P62750

0.49

MRPL23

6150

Q16540

0.49

RPL31

6160

P62899

0.49

RPLP0

6175

P05388

0.49

RPS2

6187

P15880

0.49

RPS3

6188

P23396

0.49

RPS4X

6191

P62701

0.49

RPS6

6194

P62753

0.49

RPS8

6202

P62241

0.49

RPS13

6207

P62277

0.49

RPS15A

6210

P62244

0.49

RPS16

6217

P62249

0.49

RPS20

6224

P60866

0.49

RPS23

6228

P62266

0.49

RPS24

6229

P62847

0.49

RPS26

6231

P62854

0.49

SRSF3

6428

P84103

0.49

SRSF5

6430

Q13243

0.49

SRSF7

6432

Q16629

0.49

TRA2B

6434

P62995

0.49

SOAT1

6646

P35610

0.49

SON

6651

P18583

0.49

SPTAN1

6709

Q13813

0.49

SPTBN2

6712

O15020

0.49

SSR4

6748

P51571

0.49

SUPT5H

6829

O00267

0.49

TPM4

7171

P67936

0.49

VTN

7448

P04004

0.49

YES1

7525

P07947

0.49

LAGE3

8270

Q14657

0.49

LAMTOR3

8649

Q9UHA4

0.49

SNAP23

8773

O00161

0.49

RPL14

9045

P50914

0.49

RPL23

9349

P62829

0.49

PPT2

9374

Q9UMR5

0.49

PTBP3

9991

O95758

0.49

MPHOSPH6

10200

Q99547

0.49

SF3B4

10262

Q15427

0.49

RBM14

10432

Q96PK6

0.49

MRPL28

10573

Q13084

0.49

PUF60

22827

Q9UHX1

0.49

EMC1

23065

Q8N766

0.49

SCFD1

23256

Q8WVM8

0.49

SF3B1

23451

O75533

0.49

SRRM2

23524

Q9UQ35

0.49

TXN2

25828

Q99757

0.49

MYOF

26509

Q9NZM1

0.49

TIMM13

26517

Q9Y5L4

0.49

SND1

27044

Q7KZF4

0.49

MRPS28

28957

Q9Y2Q9

0.49

NENF

29937

Q9UMX5

0.49

WDR44

54521

Q5JSH3

0.49

MRPL50

54534

Q8N5N7

0.49

SARS2

54938

Q9NP81

0.49

TBC1D2

55357

Q9BYX2

0.49

MFN1

55669

Q8IWA4

0.49

IARS2

55699

Q9NSE4

0.49

TOMM22

56993

Q9NS69

0.49

MIF4GD

57409

A9UHW6

0.49

MRPL17

63875

Q9NRX2

0.49

MRPS26

64949

Q9BYN8

0.49

MRPL38

64978

Q96DV4

0.49

MRPS34

65993

P82930

0.49

MRPL24

79590

Q96A35

0.49

PYROXD1

79912

Q8WU10

0.49

TRIM56

81844

Q9BRZ2

0.49

RAB6C

84084

Q9H0N0

0.49

SFXN1

94081

Q9H9B4

0.49

PRKCDBP

112464

Q969G5

0.49

SFXN2

118980

Q96NB2

0.49

MRPL55

128308

Q7Z7F7

0.49

MRPL21

219927

Q7Z2W9

0.49

RPLP0P6

220717

Q8NHW5

0.49

PTRF

284119

Q6NZI2

0.49

ZBTB8B

728116

Q8NAP8

0.49

RPL9; RPL9P7; RPL9P8; RPL9P9

6133

P32969

0.49

DDX3X

1654

O00571

0.63

DDX6

1656

P26196

0.63

EEF2

1938

P13639

0.63

ELAVL2

1993

Q12926

0.63

XRCC6

2547

P12956

0.63

HNRNPC

3183

P07910

0.63

HSPA1A

3303

P0DMV8

0.63

HSPA1B

3304

P0DMV9

0.63

MCM3

4172

P25205

0.63

MCM4

4173

P33991

0.63

MCM6

4175

Q14566

0.63

NOP2

4839

P46087

0.63

NVL

4931

O15381

0.63

ORC2

4999

Q13416

0.63

PTBP1

5725

P26599

0.63

UPF1

5976

Q92900

0.63

TRIM27

5987

P14373

0.63

RPL15

6138

P61313

0.63

SHMT2

6472

P34897

0.63

SRP72

6731

O76094

0.63

TARBP2

6895

Q15633

0.63

XRCC5

7520

P13010

0.63

ZNF22

7570

P17026

0.63

PABPN1

8106

Q86U42

0.63

PRKRA

8575

O75569

0.63

RUVBL1

8607

Q9Y265

0.63

PABPC4

8761

Q13310

0.63

DDX18

8886

Q9NVP1

0.63

MORF4L2

9643

Q15014

0.63

PUM3

9933

Q15397

0.63

CEBPZ

10153

Q03701

0.63

SRRM1

10250

Q8IYB3

0.63

MYBBP1A

10514

Q9BQG0

0.63

PAIP1

10605

Q9H074

0.63

IGF2BP3

10643

O00425

0.63

IGF2BP2

10644

Q9Y6M1

0.63

RUVBL2

10856

Q9Y230

0.63

MORF4L1

10933

Q9UBU8

0.63

DHX30

22907

Q7L2E3

0.63

RALY

22913

Q9UKM9

0.63

RRP1B

23076

Q14684

0.63

FAM120A

23196

Q9NZB2

0.63

PUM2

23369

Q8TB72

0.63

RRP8

23378

O43159

0.63

DICER1

23405

Q9UPY3

0.63

GTPBP4

23560

Q9BZE4

0.63

CCNDBP1

23582

O95273

0.63

ORC3

23595

Q9UBD5

0.63

PTCD1

26024

O75127

0.63

NOC2L

26155

Q9Y3T9

0.63

STAU2

27067

Q9NUL3

0.63

CCDC59

29080

Q9P031

0.63

MTERF3

51001

Q96E29

0.63

RPL26L1

51121

Q9UNX3

0.63

CDC40

51362

O60508

0.63

NIP7

51388

Q9Y221

0.63

RBM28

55131

Q9NW13

0.63

PRMT6

55170

Q96LA8

0.63

BRIX1

55299

Q8TDN6

0.63

LYAR

55646

Q9NX58

0.63

PPAN

56342

Q9NQ55

0.63

DDX31

64794

Q9H8H2

0.63

RPF2

84154

Q9H7B2

0.63

GLYR1

84656

Q49A26

0.63

ZCCHC3

85364

Q9NUD5

0.63

YTHDC1

91746

Q96MU7

0.63

IMP4

92856

Q96G21

0.63

FTSJ3

117246

Q8IY81

0.63

CENPV

201161

Q7Z7K6

0.63

KNOP1

400506

Q1ED39

0.63

RBMXL1

494115

Q96E39

0.63

STRBP

55342

Q96SI9

0.70

RAD50

10111

Q92878

0.72

EEF1A1

1915

P68104

0.73

EEF1G

1937

P26641

0.73

MCM2

4171

P49736

0.73

MOV10

4343

Q9HCE1

0.73

MRE11A

4361

P49959

0.73

RPL10A

4736

P62906

0.73

RPL6

6128

Q02878

0.73

EP300

2033

Q09472

0.75

ZFR

51663

Q96KR1

0.79

HNRNPU

3192

Q00839

0.82

PRKDC

5591

P78527

0.86

EIF4A1

1973

P60842

0.49

EWSR1

2130

Q01844

0.49

FLNA

2316

P21333

0.49

HNRNPH1

3187

P31943

0.49

HSPA5

3309

P11021

0.49

ICT1

3396

Q14197

0.49

HNRNPUL1

11100

Q9BUJ2

0.49

OSGEP

55644

Q9NPF4

0.49

DDX28

55794

Q9NUL7

0.49

ZFR2

23217

Q9UPR6

0.56

MEX3C

51320

Q5U5Q3

0.56

ABCF1

23

Q8NE71

0.63

APEX1

328

P27695

0.63

BIRC2

329

Q13490

0.63

BMI1

648

P35226

0.63

CDK2

1017

P24941

0.63

CSF2

1437

P04141

0.63

DDX1

1653

Q92499

0.63

EGFR

1956

P00533

0.63

EZH2

2146

Q15910

0.63

FKBP3

2287

Q00688

0.63

FN1

2335

P02751

0.63

ICAM1

3383

P05362

0.63

ITGA4

3676

P13612

0.63

JUN

3725

P05412

0.63

MCM7

4176

P33993

0.63

NEDD8

4738

Q15843

0.63

NMT1

4836

P30419

0.63

NTRK1

4914

P04629

0.63

PRKAA1

5562

Q13131

0.63

RFC4

5984

P35249

0.63

RPA1

6117

P27694

0.63

RPA2

6118

P15927

0.63

RPA3

6119

P35244

0.63

SUMO3

6612

P55854

0.63

AURKA

6790

O14965

0.63

TADA2A

6871

O75478

0.63

SUMO1

7341

P63165

0.63

WHSC1

7468

O96028

0.63

YWHAE

7531

P62258

0.63

CUL5

8065

Q93034

0.63

SF3A2

8175

Q15428

0.63

UBL4A

8266

P11441

0.63

CUL4B

8450

Q13620

0.63

CUL3

8452

Q13618

0.63

CUL2

8453

Q13617

0.63

CUL1

8454

Q13616

0.63

YBX3

8531

P16989

0.63

EED

8726

O75530

0.63

EIF2B3

8891

Q9NR50

0.63

EIF2B2

8892

P49770

0.63

KIAA0101

9768

Q15004

0.63

CUL7

9820

Q14999

0.63

SGSM2

9905

O43147

0.63

HDAC5

10014

Q9UQL6

0.63

HUWE1

10075

Q7Z6Z7

0.63

NOP56

10528

O00567

0.63

UBD

10537

O15205

0.63

IVNS1ABP

10625

Q9Y6Y0

0.63

COPS5

10987

Q92905

0.63

GABARAP

11337

O95166

0.63

GABARAPL2

11345

P60520

0.63

SNW1

22938

Q13573

0.63

OBSL1

23363

O75147

0.63

TARDBP

23435

Q13148

0.63

SUZ12

23512

Q15022

0.63

EDC4

23644

Q6P2E9

0.63

GABARAPL1

23710

Q9H0R8

0.63

NELFB

25920

Q8WX92

0.63

FBXO6

26270

Q9NRD1

0.63

AGO1

26523

Q9UL18

0.63

AGO2

27161

Q9UKV8

0.63

DIMT1

27292

Q9UNQ2

0.63

RTCB

51493

Q9Y3I0

0.63

SIRT7

51547

Q9NRC8

0.63

C14orf166

51637

Q9Y224

0.63

DCUN1D1

54165

Q96GG9

0.63

RIOK2

55781

Q9BVS4

0.63

CAND1

55832

Q86VP6

0.63

USE1

55850

Q9NZ43

0.63

MAP1LC3B

81631

Q9GZQ8

0.63

CCDC8

83987

Q9H0W5

0.63

MAP1LC3A

84557

Q9H492

0.63

IGSF8

93185

Q969P0

0.63

SREK1

140890

Q8WXA9

0.63

SCARNA22

677770

N/A

0.63

ESR1

2099

P03372

0.67

ERG

2078

P11308

0.68

SMURF2

64750

Q9HAU4

0.70

CDK9

1025

P50750

0.72

IFIT2

3433

P09913

0.72

IFIT1

3434

P09914

0.72

MAGOH

4116

P61326

0.72

NFKB2

4791

Q00653

0.72

RELA

5970

Q04206

0.72

MAP3K14

9020

Q99558

0.72

MATR3

9782

P43243

0.72

CBX6

23466

O95503

0.72

MEPCE

56257

Q7L2J0

0.72

CBX8

57332

Q9HC52

0.72

KHDRBS2

202559

Q5VWX1

0.72

STAU1

6780

O95793

0.73

SYNCRIP

10492

O60506

0.73

SUMO2

6613

P61956

0.74

HNRNPR

10236

O43390

0.74

PPID

5481

Q08752

0.76

H2AFX

3014

P16104

0.82

MCM5

4174

P33992

0.82

VCAM1

7412

P19320

0.82

EIF4A3

9775

P38919

0.82

LARP1

23367

Q6PKG0

0.82

DHX9

1660

Q08211

0.83

EIF2AK2

5610

P19525

0.83

HNRNPA1

3178

P09651

0.87

CDC5L

988

Q99459

0.88

YBX1

4904

P67809

0.89

ILF3

3609

Q12906

0.94