| Gene Symbol | AGFG1 |
| Entrez ID | 3267 |
| Uniprot ID | P52594 |
| Description | ArfGAP with FG repeats 1 |
| Chromosomal Location | chr2: 227,472,152-227,561,214 |
| Ontology | GO ID | GO Term | Definition | Evidence |
|---|---|---|---|---|
BP | GO:0001675 | acrosome assembly |
The formation of the acrosome from the spermatid Golgi. | IEA |
BP | GO:0006406 | mRNA export from nucleus |
The directed movement of mRNA from the nucleus to the cytoplasm. | TAS |
BP | GO:0007275 | multicellular organism development |
The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult). | IEA |
BP | GO:0007289 | spermatid nucleus differentiation |
The specialization of the spermatid nucleus during the development of a spermatid into a mature male gamete competent for fertilization. | IEA |
BP | GO:0043547 | positive regulation of GTPase activity |
Any process that activates or increases the activity of a GTPase. | IEA |
BP | GO:0045109 | intermediate filament organization |
Control of the spatial distribution of intermediate filaments; includes organizing filaments into meshworks, bundles, or other structures, as by cross-linking. | IEA |
CC | GO:0005643 | nuclear pore |
Any of the numerous similar discrete openings in the nuclear envelope of a eukaryotic cell, where the inner and outer nuclear membranes are joined. | TAS |
CC | GO:0016023 | cytoplasmic, membrane-bounded vesicle |
A membrane-bounded vesicle found in the cytoplasm of the cell. | IEA |
CC | GO:0042995 | cell projection |
A prolongation or process extending from a cell, e.g. a flagellum or axon. | IEA |
CC | GO:0043025 | neuronal cell body |
The portion of a neuron that includes the nucleus, but excludes cell projections such as axons and dendrites. | IEA |
CC | GO:0043231 | intracellular membrane-bounded organelle |
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane. | IDA |
MF | GO:0003677 | DNA binding |
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). | IEA |
MF | GO:0003723 | RNA binding |
Interacting selectively and non-covalently with an RNA molecule or a portion thereof. | TAS |
MF | GO:0005096 | GTPase activator activity |
Binds to and increases the activity of a GTPase, an enzyme that catalyzes the hydrolysis of GTP. | IEA |
MF | GO:0005515 | protein binding |
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules). | IPI |
MF | GO:0046872 | metal ion binding |
Interacting selectively and non-covalently with any metal ion. | IEA |
| Domain ID | Description |
|---|---|
IPR001164 | Arf GTPase activating protein |
| Pathway ID | Pathway Term | Pathway Source |
|---|---|---|
hsa05164 | Influenza A | KEGG |
| Tissue | Cell Type |
|---|---|
placenta | trophoblastic cells |
| Pubmed ID | Author | Year | Title |
|---|---|---|---|
22951915 | Haozi et al. | 2012 | Altered gene expression profile in cumulus cells of mature MII oocytes from patients with polycystic ovary syndrome |
| Gene Symbol | Entrez ID | Uniprot ID | Score |
|---|---|---|---|
SUCLA2 | 8803 | Q9P2R7 | 0.49 |
AGFG1 | 3267 | P52594 | 0.52 |
APP | 351 | P05067 | 0.56 |
NYAP2 | 57624 | Q9P242 | 0.63 |
POLE2 | 5427 | P56282 | 0.63 |
SURF2 | 6835 | Q15527 | 0.63 |
OGT | 8473 | O15294 | 0.63 |
ZPR1 | 8882 | O75312 | 0.63 |
GPN1 | 11321 | Q9HCN4 | 0.63 |
HSPBP1 | 23640 | Q9NZL4 | 0.63 |
TPRKB | 51002 | Q9Y3C4 | 0.63 |
SH3GLB1 | 51100 | Q9Y371 | 0.63 |
IPO11 | 51194 | Q9UI26 | 0.63 |
PPME1 | 51400 | Q9Y570 | 0.63 |
CEP170 | 9859 | Q5SW79 | 0.49 |
RNF216 | 54476 | Q9NWF9 | 0.52 |
ALAD | 210 | P13716 | 0.63 |
APC | 324 | P25054 | 0.63 |
ESR1 | 2099 | P03372 | 0.63 |
FCGR2A | 2212 | P12318 | 0.63 |
ITGA4 | 3676 | P13612 | 0.63 |
LPP | 4026 | Q93052 | 0.63 |
PKIA | 5569 | P61925 | 0.63 |
ARPC1A | 10552 | Q92747 | 0.63 |
DBNL | 28988 | Q9UJU6 | 0.63 |
LAP3 | 51056 | P28838 | 0.63 |
NIF3L1 | 60491 | Q9GZT8 | 0.63 |
P3H1 | 64175 | Q32P28 | 0.63 |
FSD1 | 79187 | Q9BTV5 | 0.63 |
RDH12 | 145226 | Q96NR8 | 0.63 |
EPS15L1 | 58513 | Q9UBC2 | 0.65 |
ITSN1 | 6453 | Q15811 | 0.7 |
MPP1 | 4354 | Q00013 | 0.72 |
VAMP7 | 6845 | P51809 | 0.78 |
VCAM1 | 7412 | P19320 | 0.82 |
XPO1 | 7514 | O14980 | 0.83 |
EPS15 | 2060 | P42566 | 0.9 |