Protein Description

Gene Symbol AGFG1
Entrez ID 3267
Uniprot ID P52594
Description ArfGAP with FG repeats 1
Chromosomal Location chr2: 227,472,152-227,561,214
Ontology GO ID GO Term Definition Evidence

BP

GO:0001675

acrosome assembly

The formation of the acrosome from the spermatid Golgi.

IEA

BP

GO:0006406

mRNA export from nucleus

The directed movement of mRNA from the nucleus to the cytoplasm.

TAS

BP

GO:0007275

multicellular organism development

The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).

IEA

BP

GO:0007289

spermatid nucleus differentiation

The specialization of the spermatid nucleus during the development of a spermatid into a mature male gamete competent for fertilization.

IEA

BP

GO:0043547

positive regulation of GTPase activity

Any process that activates or increases the activity of a GTPase.

IEA

BP

GO:0045109

intermediate filament organization

Control of the spatial distribution of intermediate filaments; includes organizing filaments into meshworks, bundles, or other structures, as by cross-linking.

IEA

CC

GO:0005643

nuclear pore

Any of the numerous similar discrete openings in the nuclear envelope of a eukaryotic cell, where the inner and outer nuclear membranes are joined.

TAS

CC

GO:0016023

cytoplasmic, membrane-bounded vesicle

A membrane-bounded vesicle found in the cytoplasm of the cell.

IEA

CC

GO:0042995

cell projection

A prolongation or process extending from a cell, e.g. a flagellum or axon.

IEA

CC

GO:0043025

neuronal cell body

The portion of a neuron that includes the nucleus, but excludes cell projections such as axons and dendrites.

IEA

CC

GO:0043231

intracellular membrane-bounded organelle

Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.

IDA

MF

GO:0003677

DNA binding

Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).

IEA

MF

GO:0003723

RNA binding

Interacting selectively and non-covalently with an RNA molecule or a portion thereof.

TAS

MF

GO:0005096

GTPase activator activity

Binds to and increases the activity of a GTPase, an enzyme that catalyzes the hydrolysis of GTP.

IEA

MF

GO:0005515

protein binding

Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).

IPI

MF

GO:0046872

metal ion binding

Interacting selectively and non-covalently with any metal ion.

IEA

Domain ID Description

IPR001164

Arf GTPase activating protein

Pathway ID Pathway Term Pathway Source

hsa05164

Influenza A

KEGG

No diseases found.

Tissue Cell Type

placenta

trophoblastic cells

No databases found.

Pubmed ID Author Year Title

22951915

Haozi et al.

2012

Altered gene expression profile in cumulus cells of mature MII oocytes from patients with polycystic ovary syndrome

Gene Symbol Entrez ID Uniprot ID Score

SUCLA2

8803

Q9P2R7

0.49

AGFG1

3267

P52594

0.52

APP

351

P05067

0.56

NYAP2

57624

Q9P242

0.63

POLE2

5427

P56282

0.63

SURF2

6835

Q15527

0.63

OGT

8473

O15294

0.63

ZPR1

8882

O75312

0.63

GPN1

11321

Q9HCN4

0.63

HSPBP1

23640

Q9NZL4

0.63

TPRKB

51002

Q9Y3C4

0.63

SH3GLB1

51100

Q9Y371

0.63

IPO11

51194

Q9UI26

0.63

PPME1

51400

Q9Y570

0.63

CEP170

9859

Q5SW79

0.49

RNF216

54476

Q9NWF9

0.52

ALAD

210

P13716

0.63

APC

324

P25054

0.63

ESR1

2099

P03372

0.63

FCGR2A

2212

P12318

0.63

ITGA4

3676

P13612

0.63

LPP

4026

Q93052

0.63

PKIA

5569

P61925

0.63

ARPC1A

10552

Q92747

0.63

DBNL

28988

Q9UJU6

0.63

LAP3

51056

P28838

0.63

NIF3L1

60491

Q9GZT8

0.63

P3H1

64175

Q32P28

0.63

FSD1

79187

Q9BTV5

0.63

RDH12

145226

Q96NR8

0.63

EPS15L1

58513

Q9UBC2

0.65

ITSN1

6453

Q15811

0.70

MPP1

4354

Q00013

0.72

VAMP7

6845

P51809

0.78

VCAM1

7412

P19320

0.82

XPO1

7514

O14980

0.83

EPS15

2060

P42566

0.90