Gene Symbol | HOXA1 |
Entrez ID | 3198 |
Uniprot ID | P49639 |
Description | homeobox A1 |
Chromosomal Location | chr7: 27,092,993-27,095,996 |
Ontology | GO ID | GO Term | Definition | Evidence |
---|---|---|---|---|
BP |
GO:0006351 |
transcription, DNA-templated |
The cellular synthesis of RNA on a template of DNA. |
IEA |
BP |
GO:0006355 |
regulation of transcription, DNA-templated |
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription. |
IEA |
BP |
GO:0007275 |
multicellular organism development |
The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult). |
TAS |
BP |
GO:0007605 |
sensory perception of sound |
The series of events required for an organism to receive an auditory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Sonic stimuli are detected in the form of vibrations and are processed to form a sound. |
IDA |
BP |
GO:0007634 |
optokinetic behavior |
The behavior of an organism pertaining to movement of the eyes and of objects in the visual field, as in nystagmus. |
IDA |
BP |
GO:0009653 |
anatomical structure morphogenesis |
The process in which anatomical structures are generated and organized. Morphogenesis pertains to the creation of form. |
IMP |
BP |
GO:0021599 |
abducens nerve formation |
The process that gives rise to the abducens nerve. This process pertains to the initial formation of a structure from unspecified parts. The motor function of the abducens nerve is to contract the lateral rectus which results in abduction of the eye. |
IMP |
BP |
GO:0042473 |
outer ear morphogenesis |
The process in which the anatomical structures of the outer ear are generated and organized. The outer ear is the part of the ear external to the tympanum (eardrum). It consists of a tube (the external auditory meatus) that directs sound waves on to the tympanum, and may also include the external pinna, which extends beyond the skull. |
IDA |
BP |
GO:0048702 |
embryonic neurocranium morphogenesis |
The process in which the anatomical structures of the neurocranium are generated and organized during the embryonic phase. The neurocranium is the portion of the vertebrate skull surrounding the brain. |
IMP |
BP |
GO:0048839 |
inner ear development |
The process whose specific outcome is the progression of the inner ear over time, from its formation to the mature structure. |
IMP |
BP |
GO:0048844 |
artery morphogenesis |
The process in which the anatomical structures of arterial blood vessels are generated and organized. Arteries are blood vessels that transport blood from the heart to the body and its organs. |
IMP |
BP |
GO:0050795 |
regulation of behavior |
Any process that modulates the frequency, rate or extent of behavior, the internally coordinated responses (actions or inactions) of whole living organisms (individuals or groups) to internal or external stimuli. |
IDA |
BP |
GO:0050890 |
cognition |
The operation of the mind by which an organism becomes aware of objects of thought or perception; it includes the mental activities associated with thinking, learning, and memory. |
IDA |
BP |
GO:0050905 |
neuromuscular process |
Any process pertaining to the functions of the nervous and muscular systems of an organism. |
IDA |
BP |
GO:0060840 |
artery development |
The progression of the artery over time, from its initial formation to the mature structure. An artery is a blood vessel that carries blood away from the heart to a capillary bed. |
IMP |
BP |
GO:0060876 |
semicircular canal formation |
The developmental process pertaining to the initial formation of the semicircular canal from the otic vesicle. This process begins with the regionalization of the vesicle that specifies the area where the vesicles will form and continues through the process of fusion which forms the initial tubes. |
IMP |
BP |
GO:0090102 |
cochlea development |
The progression of the cochlea over time from its formation to the mature structure. The cochlea is the snail-shaped portion of the inner ear that is responsible for the detection of sound. |
IMP |
BP |
GO:0090103 |
cochlea morphogenesis |
The process in which the cochlea is generated and organized. |
IMP |
CC |
GO:0005634 |
nucleus |
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
IEA |
MF |
GO:0005515 |
protein binding |
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules). |
IPI |
MF |
GO:0043565 |
sequence-specific DNA binding |
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding. |
IEA |
Domain ID | Description |
---|---|
IPR001356 |
Homeobox domain |
IPR009057 |
Homeobox domain-like |
IPR017970 |
Homeobox, conserved site |
IPR020479 |
Homeobox domain, metazoa |
Pathway ID | Pathway Term | Pathway Source |
---|---|---|
WP2064 |
Neural Crest Differentiation |
WikiPathways |
WP2853 |
Endoderm Differentiation |
WikiPathways |
UMLS CUI | UMLS Term |
---|---|
C0004352 |
Autistic Disorder |
C0018798 |
Congenital Heart Defects |
C0376634 |
Craniofacial Abnormalities |
C0497552 |
Congenital Neurologic Anomalies |
Pubmed ID | Author | Year | Title |
---|---|---|---|
22951915 |
Haozi et al. |
2012 |
Altered gene expression profile in cumulus cells of mature MII oocytes from patients with polycystic ovary syndrome |
Gene Symbol | Entrez ID | Uniprot ID | Score |
---|---|---|---|
TCF3 |
6929 |
P15923 |
0.52 |
KRT31 |
3881 |
Q15323 |
0.63 |
PBX1 |
5087 |
P40424 |
0.63 |
PBX2 |
5089 |
P40425 |
0.63 |
PCSK5 |
5125 |
Q92824 |
0.63 |
SDCBP |
6386 |
O00560 |
0.63 |
TLE1 |
7088 |
Q04724 |
0.63 |
TRAF1 |
7185 |
Q13077 |
0.63 |
BLZF1 |
8548 |
Q9H2G9 |
0.63 |
CHRD |
8646 |
Q9H2X0 |
0.63 |
KRT38 |
8687 |
O76015 |
0.63 |
CHIC2 |
26511 |
Q9UKJ5 |
0.63 |
RGS17 |
26575 |
Q9UGC6 |
0.63 |
ALG13 |
79868 |
Q9NP73 |
0.63 |
CCDC33 |
80125 |
Q8N5R6 |
0.63 |
ZNF703 |
80139 |
Q9H7S9 |
0.63 |
KRTAP9-2 |
83899 |
Q9BYQ4 |
0.63 |
PRRC2B |
84726 |
Q5JSZ5 |
0.63 |
ZNF503 |
84858 |
Q96F45 |
0.63 |
KRTAP9-4 |
85280 |
Q9BYQ2 |
0.63 |
KRTAP4-2 |
85291 |
Q9BYR5 |
0.63 |
KRT40 |
125115 |
Q6A162 |
0.63 |
HSFY1 |
159119 |
Q96LI6 |
0.63 |
LCE4A |
199834 |
Q5TA78 |
0.63 |
TRIM42 |
287015 |
Q8IWZ5 |
0.63 |
LCE1B |
353132 |
Q5T7P3 |
0.63 |
LCE3E |
353145 |
Q5T5B0 |
0.63 |
KRTAP12-2 |
353323 |
P59991 |
0.63 |
KRTAP12-1 |
353332 |
P59990 |
0.63 |
TBC1D10C |
374403 |
Q8IV04 |
0.63 |
KRTAP10-9 |
386676 |
P60411 |
0.63 |
KRTAP10-1 |
386677 |
P60331 |
0.63 |
KRTAP10-11 |
386678 |
P60412 |
0.63 |
KRTAP10-5 |
386680 |
P60370 |
0.63 |
KRTAP10-8 |
386681 |
P60410 |
0.63 |
KRTAP10-3 |
386682 |
P60369 |
0.63 |
KRTAP12-4 |
386684 |
P60329 |
0.63 |
NOTCH2NL |
388677 |
Q7Z3S9 |
0.63 |
KRTAP5-6 |
440023 |
Q6L8G9 |
0.63 |
KRTAP4-11 |
653240 |
Q9BYQ6 |
0.63 |
DUSP22 |
56940 |
Q9NRW4 |
0.63 |
KDM1A |
23028 |
O60341 |
0.72 |
PRMT6 |
55170 |
Q96LA8 |
0.72 |
SPRY1 |
10252 |
O43609 |
0.73 |
KRTAP3-2 |
83897 |
Q9BYR7 |
0.82 |
KRTAP26-1 |
388818 |
Q6PEX3 |
0.82 |
HOXA1 |
3198 |
P49639 |
0.83 |
PLSCR1 |
5359 |
O15162 |
0.83 |
TRIP6 |
7205 |
Q15654 |
0.83 |
PKNOX1 |
5316 |
P55347 |
0.84 |
LPXN |
9404 |
O60711 |
0.86 |
TRAPPC6A |
79090 |
O75865 |
0.86 |
MDFI |
4188 |
Q99750 |
0.87 |
EFEMP2 |
30008 |
O95967 |
0.87 |
KRTAP4-12 |
83755 |
Q9BQ66 |
0.87 |
KRTAP4-7 |
100132476 |
Q9BYR0 |
0.63 |
TRIM23 |
373 |
P36406 |
0.63 |
GATA1 |
2623 |
P15976 |
0.63 |
PIK3R1 |
5295 |
P27986 |
0.63 |
TRAF2 |
7186 |
Q12933 |
0.63 |
ZBTB16 |
7704 |
Q05516 |
0.63 |
PDLIM7 |
9260 |
Q9NR12 |
0.63 |
RBCK1 |
10616 |
Q9BYM8 |
0.63 |
KDM5B |
10765 |
Q9UGL1 |
0.63 |
ZBTB32 |
27033 |
Q9Y2Y4 |
0.63 |
SMOC1 |
64093 |
Q9H4F8 |
0.63 |
HOXD3 |
3232 |
P31249 |
0.72 |
KRT81 |
3887 |
Q14533 |
0.72 |
LIMS1 |
3987 |
P48059 |
0.72 |
PITX2 |
5308 |
Q99697 |
0.72 |
RAB33A |
9363 |
Q14088 |
0.72 |
FHL5 |
9457 |
Q5TD97 |
0.72 |
PDCD6IP |
10015 |
Q8WUM4 |
0.72 |
IKZF2 |
22807 |
Q9UKS7 |
0.72 |
ZZZ3 |
26009 |
Q8IYH5 |
0.72 |
PLSCR4 |
57088 |
Q9NRQ2 |
0.72 |
ABHD17A |
81926 |
Q96GS6 |
0.72 |
CRACR2A |
84766 |
Q9BSW2 |
0.72 |
C1orf94 |
84970 |
Q6P1W5 |
0.72 |
SAXO1 |
158297 |
Q8IYX7 |
0.72 |
LNX2 |
222484 |
Q8N448 |
0.72 |
GP9 |
2815 |
P14770 |
0.73 |
GRN |
2896 |
P28799 |
0.74 |
SUV39H1 |
6839 |
O43463 |
0.76 |
PRNP |
5621 |
P04156 |
0.78 |
RGS20 |
8601 |
O76081 |
0.82 |
N4BP2L2 |
10443 |
Q92802 |
0.82 |
RBPMS |
11030 |
Q93062 |
0.82 |
KRTAP5-9 |
3846 |
P26371 |
0.86 |
LGALS13 |
29124 |
Q9UHV8 |
0.86 |
ADAMTSL4 |
54507 |
Q6UY14 |
0.86 |
MGAT5B |
146664 |
Q3V5L5 |
0.86 |