PCOSBase

Protein Description

Gene Symbol	HNRNPU
Entrez ID	3192
Uniprot ID	Q00839
Description	heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
Chromosomal Location	chr1: 244,840,638-244,864,560

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Ontology	GO ID	GO Term	Definition	Evidence
BP	GO:0000398	mRNA splicing, via spliceosome	The joining together of exons from one or more primary transcripts of messenger RNA (mRNA) and the excision of intron sequences, via a spliceosomal mechanism, so that mRNA consisting only of the joined exons is produced.	IC\|TAS
BP	GO:0001649	osteoblast differentiation	The process whereby a relatively unspecialized cell acquires the specialized features of an osteoblast, a mesodermal or neural crest cell that gives rise to bone.	IDA
BP	GO:0006396	RNA processing	Any process involved in the conversion of one or more primary RNA transcripts into one or more mature RNA molecules.	TAS
BP	GO:0010467	gene expression	The process in which a gene's sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.	TAS
BP	GO:0010628	positive regulation of gene expression	Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.	IEA
BP	GO:0032211	negative regulation of telomere maintenance via telomerase	Any process that stops, prevents, or reduces the frequency, rate or extent of the addition of telomeric repeats by telomerase.	IMP
BP	GO:0032922	circadian regulation of gene expression	Any process that modulates the frequency, rate or extent of gene expression such that an expression pattern recurs with a regularity of approximately 24 hours.	ISS
BP	GO:0055013	cardiac muscle cell development	The process whose specific outcome is the progression of a cardiac muscle cell over time, from its formation to the mature state.	IEA
BP	GO:0070934	CRD-mediated mRNA stabilization	An mRNA stabilization process in which one or more RNA-binding proteins associate with a sequence in the open reading frame called the coding region instability determinant (CRD).	IMP
BP	GO:0071549	cellular response to dexamethasone stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dexamethasone stimulus.	IEA
BP	GO:2000373	positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity	Any process that activates or increases the frequency, rate or extent of DNA topoisomerase (ATP-hydrolyzing) activity.	IEA
CC	GO:0005634	nucleus	A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.	IDA
CC	GO:0005654	nucleoplasm	That part of the nuclear content other than the chromosomes or the nucleolus.	IDA\|TAS
CC	GO:0005697	telomerase holoenzyme complex	Telomerase is a ribonucleoprotein enzyme complex, with a minimal catalytic core composed of a catalytic reverse transcriptase subunit and an RNA subunit that provides the template for telomeric DNA addition. In vivo, the holoenzyme complex often contains additional subunits.	IDA
CC	GO:0009986	cell surface	The external part of the cell wall and/or plasma membrane.	IEA
CC	GO:0016020	membrane	A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.	IDA
CC	GO:0030529	intracellular ribonucleoprotein complex	An intracellular macromolecular complex containing both protein and RNA molecules.	IDA
CC	GO:0031012	extracellular matrix	A structure lying external to one or more cells, which provides structural support for cells or tissues.	IDA
CC	GO:0036464	cytoplasmic ribonucleoprotein granule	A ribonucleoprotein granule located in the cytoplasm.	IDA
CC	GO:0070937	CRD-mediated mRNA stability complex	A protein complex that binds to, and promotes stabilization of, mRNA molecules containing the coding region instability determinant (CRD). In human, IGF2BP1 and at least four additional proteins: HNRNPU, SYNCRIP, YBX1, and DHX9.	IDA
CC	GO:0071013	catalytic step 2 spliceosome	A spliceosomal complex that contains three snRNPs, including U5, bound to a splicing intermediate in which the first catalytic cleavage of the 5' splice site has occurred. The precise subunit composition differs significantly from that of the catalytic step 1, or activated, spliceosome, and includes many proteins in addition to those found in the associated snRNPs.	IDA
MF	GO:0001047	core promoter binding	Interacting selectively and non-covalently with the regulatory region composed of the transcription start site and binding sites for the basal transcription machinery. Binding may occur as a sequence specific interaction or as an interaction observed only once a factor has been recruited to the DNA by other factors.	ISS
MF	GO:0003677	DNA binding	Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).	TAS
MF	GO:0003723	RNA binding	Interacting selectively and non-covalently with an RNA molecule or a portion thereof.	TAS
MF	GO:0005515	protein binding	Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).	IPI
MF	GO:0005524	ATP binding	Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.	IEA
MF	GO:0034046	poly(G) binding	Interacting selectively and non-covalently with a sequence of guanine residues in an RNA molecule.	IEA
MF	GO:0035326	enhancer binding	Interacting selectively and non-covalently with an enhancer, a transcription regulatory region that is somewhat distal from the core promoter and which enhances transcription from that promoter.	IEA
MF	GO:0043021	ribonucleoprotein complex binding	Interacting selectively and non-covalently with any complex of RNA and protein.	IEA
MF	GO:0044822	poly(A) RNA binding	Interacting non-covalently with a poly(A) RNA, a RNA molecule which has a tail of adenine bases.	IDA
MF	GO:0070034	telomerase RNA binding	Interacting selectively and non-covalently with the telomerase RNA template.	IPI

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Domain ID	Description
IPR001870	B30.2/SPRY domain
IPR003034	SAP domain
IPR003877	SPRY domain
IPR013320	Concanavalin A-like lectin/glucanase domain
IPR026745	Heterogeneous nuclear ribonucleoprotein U
IPR027417	P-loop containing nucleoside triphosphate hydrolase

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Pathway ID	Pathway Term	Pathway Source
hsa03040	Spliceosome	KEGG
WP411	mRNA Processing	WikiPathways
WP3594	Circadian rythm related genes	WikiPathways

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No diseases found.

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Tissue	Cell Type
adrenal gland	glandular cells
appendix	glandular cells
appendix	lymphoid tissue
bone marrow	hematopoietic cells
breast	adipocytes
breast	glandular cells
breast	myoepithelial cells
bronchus	respiratory epithelial cells
caudate	glial cells
caudate	neuronal cells
cerebellum	cells in molecular layer
cerebellum	Purkinje cells
cerebral cortex	endothelial cells
cerebral cortex	glial cells
cerebral cortex	neuronal cells
cervix, uterine	glandular cells
cervix, uterine	squamous epithelial cells
colon	endothelial cells
colon	glandular cells
duodenum	glandular cells
endometrium	glandular cells
epididymis	glandular cells
esophagus	squamous epithelial cells
fallopian tube	glandular cells
gallbladder	glandular cells
heart muscle	myocytes
hippocampus	glial cells
hippocampus	neuronal cells
kidney	cells in glomeruli
kidney	cells in tubules
lung	macrophages
lung	pneumocytes
lymph node	germinal center cells
lymph node	non-germinal center cells
nasopharynx	respiratory epithelial cells
oral mucosa	squamous epithelial cells
pancreas	exocrine glandular cells
pancreas	islets of Langerhans
placenta	decidual cells
placenta	trophoblastic cells
prostate	glandular cells
rectum	glandular cells
salivary gland	glandular cells
seminal vesicle	glandular cells
skeletal muscle	myocytes
skin	fibroblasts
skin	keratinocytes
skin	Langerhans
skin	melanocytes
skin	epidermal cells
small intestine	glandular cells
smooth muscle	smooth muscle cells
soft tissue	chondrocytes
soft tissue	fibroblasts
spleen	cells in red pulp
stomach	glandular cells
testis	cells in seminiferous ducts
testis	Leydig cells
thyroid gland	glandular cells
tonsil	germinal center cells
tonsil	non-germinal center cells
tonsil	squamous epithelial cells
urinary bladder	urothelial cells
vagina	squamous epithelial cells

No databases found.

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Pubmed ID	Author	Year	Title
17148555	Wood et al.	2007	Molecular Abnormalities in Oocytes from Women with Polycystic Ovary Syndrome Revealed by Microarray Analysis
22617121	Ouandaogo et al.	2012	Differences in transcriptomic profiles of human cumulus cells isolated from oocytes at GV, MI and MII stages after in vivo andin vitro oocyte maturation
22951915	Haozi et al.	2012	Altered gene expression profile in cumulus cells of mature MII oocytes from patients with polycystic ovary syndrome

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Gene Symbol	Entrez ID	Uniprot ID	Score
RHOB	388	P62745	0.49
ATP6V1B1	525	P15313	0.49
CALR	811	P27797	0.49
SEPT7	989	Q16181	0.49
GTF3C1	2975	Q12789	0.49
ICT1	3396	Q14197	0.49
IK	3550	Q13123	0.49
IL7R	3575	P16871	0.49
ITGA5	3678	P08648	0.49
ITGB4	3691	P16144	0.49
EIF6	3692	P56537	0.49
KRT3	3850	P12035	0.49
KRT14	3861	P02533	0.49
LAMP2	3920	P13473	0.49
LBR	3930	Q14739	0.49
LIMS1	3987	P48059	0.49
LMAN1	3998	P49257	0.49
MARCKS	4082	P29966	0.49
MYH9	4627	P35579	0.49
SEPT2	4735	Q15019	0.49
NFIA	4774	Q12857	0.49
SNU13	4809	P55769	0.49
NONO	4841	Q15233	0.49
PCDH7	5099	O60245	0.49
PDHA2	5161	P29803	0.49
PRPH	5630	P41219	0.49
PTPN1	5770	P18031	0.49
UPF1	5976	Q92900	0.49
RPL12	6136	P30050	0.49
MRPL23	6150	Q16540	0.49
RPLP1	6176	P05386	0.49
RPN1	6184	P04843	0.49
RPS23	6228	P62266	0.49
RPS26	6231	P62854	0.49
S100A9	6280	P06702	0.49
SRSF1	6426	Q07955	0.49
SRSF3	6428	P84103	0.49
SRSF7	6432	Q16629	0.49
TRA2B	6434	P62995	0.49
SNRNP70	6625	P08621	0.49
SNRPA	6626	P09012	0.49
SNRPA1	6627	P09661	0.49
SNRPD1	6632	P62314	0.49
TPBG	7162	Q13641	0.49
TPR	7175	P12270	0.49
HSP90B1	7184	P14625	0.49
U2AF1	7307	Q01081	0.49
VDAC2	7417	P45880	0.49
VTN	7448	P04004	0.49
SLC7A5	8140	Q01650	0.49
SART1	9092	O43290	0.49
PRPF4	9128	O43172	0.49
SRSF11	9295	Q05519	0.49
EFTUD2	9343	Q15029	0.49
LAPTM4A	9741	Q15012	0.49
PSMD6	9861	Q15008	0.49
THRAP3	9967	Q9Y2W1	0.49
SAP18	10284	O00422	0.49
SF3A1	10291	Q15459	0.49
SLC25A17	10478	O43808	0.49
PRPF8	10594	Q6P2Q9	0.49
USP39	10713	Q53GS9	0.49
UTP14A	10813	Q9BVJ6	0.49
PGRMC1	10857	O00264	0.49
RNPS1	10921	Q15287	0.49
U2AF2	11338	P26368	0.49
RALY	22913	Q9UKM9	0.49
SNRNP200	23020	O75643	0.49
RRS1	23212	Q15050	0.49
NCSTN	23385	Q92542	0.49
SRRM2	23524	Q9UQ35	0.49
MTCH1	23787	Q9NZJ7	0.49
MTCH2	23788	Q9Y6C9	0.49
PTCD1	26024	O75127	0.49
LSM14A	26065	Q8ND56	0.49
PABPC1	26986	P11940	0.49
RRP7A	27341	Q9Y3A4	0.49
MRPS28	28957	Q9Y2Q9	0.49
MRPL42	28977	Q9Y6G3	0.49
MRPL13	28998	Q9BYD1	0.49
TRA2A	29896	Q13595	0.49
MRPS16	51021	Q9Y3D3	0.49
TMX2	51075	Q9Y320	0.49
MRPL51	51258	Q4U2R6	0.49
MRPL48	51642	Q96GC5	0.49
LUC7L3	51747	O95232	0.49
SMU1	55234	Q2TAY7	0.49
PCDHA2	56146	Q9Y5H9	0.49
WDR18	57418	Q9BV38	0.49
MRPL44	65080	Q9H9J2	0.49
SLC25A32	81034	Q9H2D1	0.49
WBSCR16	81554	Q96I51	0.49
TRIM55	84675	Q9BYV6	0.49
KIAA2013	90231	Q8IYS2	0.49
MRPL52	122704	Q86TS9	0.49
ZC3H18	124245	Q86VM9	0.49
MRPL10	124995	Q7Z7H8	0.49
RPL10L	140801	Q96L21	0.49
HNRNPA3	220988	P51991	0.49
GRIN2D	2906	O15399	0.52
GTF2H1	2965	P32780	0.52
SYK	6850	P43405	0.52
ELL	8178	P55199	0.52
CD5	921	P06127	0.55
RPLP2	6181	P05387	0.59
FLNC	2318	Q14315	0.63
HNRNPH3	3189	P31942	0.63
HSPB1	3315	P04792	0.63
RPSA	3921	P08865	0.63
MAX	4149	P61244	0.63
MRE11A	4361	P49959	0.63
MYC	4609	P01106	0.63
NFKBIA	4792	P25963	0.63
RPL17	6139	P18621	0.63
RPL26	6154	P61254	0.63
TPD52	7163	P55327	0.63
G3BP1	10146	Q13283	0.63
FCF1	51077	Q9Y324	0.63
MRPL27	51264	Q9P0M9	0.63
DDX24	57062	Q9GZR7	0.63
DDX31	64794	Q9H8H2	0.63
C12orf43	64897	Q96C57	0.63
KRBA2	124751	Q6ZNG9	0.63
POC1B	282809	Q8TC44	0.63
RPS21	100291837	P63220	0.63
SMN1; SMN2	6606	Q16637	0.65
UBQLN2	29978	Q9UHD9	0.68
CACNA2D1	781	P54289	0.72
CHD1	1105	O14646	0.72
DDX5	1655	P17844	0.72
EIF2B1	1967	Q14232	0.72
ERCC6	2074	Q03468	0.72
FBL	2091	P22087	0.72
HIST1H1B	3009	P16401	0.72
HNRNPA2B1	3181	P22626	0.72
HNRNPAB	3182	Q99729	0.72
HNRNPC	3183	P07910	0.72
HNRNPL	3191	P14866	0.72
HSD17B4	3295	P51659	0.72
IFI16	3428	Q16666	0.72
IGHMBP2	3508	P38935	0.72
ILF3	3609	Q12906	0.72
RPL10A	4736	P62906	0.72
NVL	4931	O15381	0.72
EXOSC10	5394	Q01780	0.72
RFC1	5981	P35251	0.72
RFC2	5982	P35250	0.72
RFC3	5983	P40938	0.72
RFC5	5985	P40937	0.72
RPL3	6122	P39023	0.72
RPL4	6124	P36578	0.72
RPL8	6132	P62917	0.72
RPL11	6135	P62913	0.72
RPL13	6137	P26373	0.72
RPL15	6138	P61313	0.72
RPL21	6144	P46778	0.72
RPL24	6152	P83731	0.72
RPL27	6155	P61353	0.72
RPL27A	6157	P46776	0.72
RPL28	6158	P46779	0.72
RPL32	6161	P62910	0.72
RPL36A	6173	P83881	0.72
RPS5	6193	P46782	0.72
RPS7	6201	P62081	0.72
RPS9	6203	P46781	0.72
RPS10	6204	P46783	0.72
RPS12	6206	P25398	0.72
RPS15	6209	P62841	0.72
RPS17	6218	P08708	0.72
RPS18	6222	P62269	0.72
RPS19	6223	P39019	0.72
SRP72	6731	O76094	0.72
SURF6	6838	O75683	0.72
TOP2A	7153	P11388	0.72
UBA52	7311	P62987	0.72
UBTF	7343	P17480	0.72
DAP3	7818	P51398	0.72
HIST1H2BL	8340	Q99880	0.72
SMARCA5	8467	O60264	0.72
PABPC4	8761	Q13310	0.72
DDX18	8886	Q9NVP1	0.72
EIF2B4	8890	Q9UI10	0.72
H1FX	8971	Q92522	0.72
BAZ1B	9031	Q9UIG0	0.72
DDX21	9188	Q9NR30	0.72
RPL23	9349	P62829	0.72
TTC37	9652	Q6PGP7	0.72
PHF14	9678	O94880	0.72
ESPL1	9700	Q14674	0.72
PUM3	9933	Q15397	0.72
HNRNPDL	9987	O14979	0.72
CEBPZ	10153	Q03701	0.72
ALYREF	10189	Q86V81	0.72
HNRNPR	10236	O43390	0.72
NPM3	10360	O75607	0.72
MYBBP1A	10514	Q9BQG0	0.72
RPP38	10557	P78345	0.72
TBL3	10607	Q12788	0.72
IGF2BP1	10642	Q9NZI8	0.72
WDR3	10885	Q9UNX4	0.72
POP1	10940	Q99575	0.72
EBNA1BP2	10969	Q99848	0.72
KRR1	11103	Q13601	0.72
SUPT16H	11198	Q9Y5B9	0.72
XRN2	22803	Q9H0D6	0.72
DHX30	22907	Q7L2E3	0.72
PDCD11	22984	Q14690	0.72
RBM34	23029	P42696	0.72
RRP1B	23076	Q14684	0.72
MRPS27	23107	Q92552	0.72
PHF8	23133	Q9UPP1	0.72
METAP1	23173	P53582	0.72
FAM120A	23196	Q9NZB2	0.72
RRP12	23223	Q5JTH9	0.72
LARP1	23367	Q6PKG0	0.72
RPL13A	23521	P40429	0.72
GTPBP4	23560	Q9BZE4	0.72
NEPRO	25871	Q6NW34	0.72
RPL36	25873	Q9Y3U8	0.72
SPATS2L	26010	Q9NUQ6	0.72
SERBP1	26135	Q8NC51	0.72
NOC2L	26155	Q9Y3T9	0.72
FBXL6	26233	Q8N531	0.72
GNL3	26354	Q9BVP2	0.72
AATF	26574	Q9NY61	0.72
MRPL46	26589	Q9H2W6	0.72
TRUB2	26995	O95900	0.72
STAU2	27067	Q9NUL3	0.72
C19orf53	28974	Q9UNZ5	0.72
UHRF1	29128	Q96T88	0.72
GNL2	29889	Q13823	0.72
PKN3	29941	Q6P5Z2	0.72
HP1BP3	50809	Q5SSJ5	0.72
RRP15	51018	Q9Y3B9	0.72
UTP18	51096	Q9Y5J1	0.72
MRPS2	51116	Q9Y399	0.72
MRTO4	51154	Q9UKD2	0.72
HERC5	51191	Q9UII4	0.72
DDX47	51202	Q9H0S4	0.72
NIP7	51388	Q9Y221	0.72
RTCB	51493	Q9Y3I0	0.72
ESF1	51575	Q9H501	0.72
MRPS33	51650	Q9Y291	0.72
DHX29	54505	Q7Z478	0.72
GNL3L	54552	Q9NVN8	0.72
GTPBP2	54676	Q9BX10	0.72
FOCAD	54914	Q5VW36	0.72
FAM120C	54954	Q9NX05	0.72
CDCA4	55038	Q9BXL8	0.72
RBM28	55131	Q9NW13	0.72
SRBD1	55133	Q8N5C6	0.72
NAT10	55226	Q9H0A0	0.72
BRIX1	55299	Q8TDN6	0.72
LYAR	55646	Q9NX58	0.72
DDX27	55661	Q96GQ7	0.72
TSR1	55720	Q2NL82	0.72
NKRF	55922	O15226	0.72
MEPCE	56257	Q7L2J0	0.72
BCCIP	56647	Q9P287	0.72
PNO1	56902	Q9NRX1	0.72
DHX33	56919	Q9H6R0	0.72
AVEN	57099	Q9NQS1	0.72
REXO4	57109	Q9GZR2	0.72
THAP11	57215	Q96EK4	0.72
CBX8	57332	Q9HC52	0.72
USP36	57602	Q9P275	0.72
MRPS35	60488	P82673	0.72
EEFSEC	60678	P57772	0.72
MRPS14	63931	O60783	0.72
NOC3L	64318	Q8WTT2	0.72
MRPS25	64432	P82663	0.72
YTHDC2	64848	Q9H6S0	0.72
MRPS15	64960	P82914	0.72
MRPS9	64965	P82933	0.72
MRPL38	64978	Q96DV4	0.72
NBEAL1	65065	Q6ZS30	0.72
NOL6	65083	Q9H6R4	0.72
KRI1	65095	Q8N9T8	0.72
SPATS2	65244	Q86XZ4	0.72
DDX50	79009	Q9BQ39	0.72
DDX54	79039	Q8TDD1	0.72
CCDC86	79080	Q9H6F5	0.72
NO66	79697	Q9H6W3	0.72
MUS81	80198	Q96NY9	0.72
PRR3	80742	P79522	0.72
TRMT1L	81627	Q7Z2T5	0.72
C18orf21	83608	Q32NC0	0.72
UTP23	84294	Q9BRU9	0.72
GLYR1	84656	Q49A26	0.72
MINA	84864	Q8IUF8	0.72
LTV1	84946	Q96GA3	0.72
SAMD1	90378	Q6SPF0	0.72
TADA1	117143	Q96BN2	0.72
WDR36	134430	Q8NI36	0.72
RPP25L	138716	Q8N5L8	0.72
EME1	146956	Q96AY2	0.72
CENPV	201161	Q7Z7K6	0.72
CCDC137	339230	Q6PK04	0.72
RPL9; RPL9P7; RPL9P8; RPL9P9	6133	P32969	0.72
NR3C1	2908	P04150	0.73
HSPA9	3313	P38646	0.73
MCM5	4174	P33992	0.73
PTBP1	5725	P26599	0.73
RPL19	6143	P84098	0.73
EIF4A3	9775	P38919	0.73
NDN	4692	Q99608	0.74
CDKN2A	1029	P42771	0.76
EP300	2033	Q09472	0.79
POU3F4	5456	P49335	0.80
NOP2	4839	P46087	0.82
RPL5	6125	P46777	0.82
RPL6	6128	Q02878	0.82
RPL7	6129	P18124	0.82
RPL7A	6130	P62424	0.82
RPL18A	6142	Q02543	0.82
RPL30	6156	P62888	0.82
RPLP0	6175	P05388	0.82
RPS2	6187	P15880	0.82
RPS3	6188	P23396	0.82
RPS4X	6191	P62701	0.82
RPS8	6202	P62241	0.82
RPS11	6205	P62280	0.82
RPS13	6207	P62277	0.82
RPS14	6208	P62263	0.82
RPS15A	6210	P62244	0.82
RPS16	6217	P62249	0.82
RPS24	6229	P62847	0.82
HNRNPA0	10949	Q13151	0.82
RSL1D1	26156	O76021	0.82
NOP58	51602	Q9Y2X3	0.82
MRPS34	65993	P82930	0.82
FTSJ3	117246	Q8IY81	0.82
HNRNPA1	3178	P09651	0.83
RFC4	5984	P35249	0.83
RPL23A	6147	P62750	0.83
RPS6	6194	P62753	0.83
SND1	27044	Q7KZF4	0.83
STAU1	6780	O95793	0.84
CDK7	1022	P50613	0.86
HNRNPD	3184	Q14103	0.86
POLR2A	5430	P24928	0.86
ZNF622	90441	Q969S3	0.86
SYNCRIP	10492	O60506	0.87
RPL18	6141	Q07020	0.89
E2F3	1871	O00716	0.07
SLC25A5	292	P05141	0.49
ATP5A1	498	P25705	0.49
HSPA5	3309	P11021	0.49
RAB2A	5862	P61019	0.49
SAFB	6294	Q15424	0.49
EIF3J	8669	O75822	0.49
TRIP10	9322	Q15642	0.49
MDC1	9656	Q14676	0.49
MATR3	9782	P43243	0.49
PDCD6	10016	O75340	0.49
WRAP53	55135	Q9BUR4	0.49
PPP4R3B	57223	Q5MIZ7	0.49
BTF3L4	91408	Q96K17	0.49
CR2	1380	P20023	0.52
GRIN1	2902	Q05586	0.52
PTPN11	5781	Q06124	0.52
UBE2I	7329	P63279	0.52
CASP3	836	P42574	0.55
YAP1	10413	P46937	0.55
CD247	919	P20963	0.56
HNRNPK	3190	P61978	0.59
ABCF1	23	Q8NE71	0.63
ADRB2	154	P07550	0.63
ADRBK1	156	P25098	0.63
CD81	975	P60033	0.63
CDC5L	988	Q99459	0.63
CDK2	1017	P24941	0.63
CENPA	1058	P49450	0.63
CRY1	1407	Q16526	0.63
MAPK14	1432	Q16539	0.63
CSNK1A1	1452	P48729	0.63
CSNK1E	1454	P49674	0.63
CSNK2A2	1459	P19784	0.63
DDX1	1653	Q92499	0.63
ESR1	2099	P03372	0.63
FKBP3	2287	Q00688	0.63
FN1	2335	P02751	0.63
NR5A1	2516	Q13285	0.63
GALE	2582	Q14376	0.63
GRK5	2869	P34947	0.63
HTR7	3363	P34969	0.63
ICAM1	3383	P05362	0.63
ILK	3611	Q13418	0.63
INPPL1	3636	O15357	0.63
ITGA4	3676	P13612	0.63
JUN	3725	P05412	0.63
KRT18	3875	P05783	0.63
LGALS3BP	3959	Q08380	0.63
MCM2	4171	P49736	0.63
NEDD8	4738	Q15843	0.63
NFKB1	4790	P19838	0.63
NFKBIB	4793	Q15653	0.63
NFX1	4799	Q12986	0.63
NMT1	4836	P30419	0.63
NTRK1	4914	P04629	0.63
PARK2	5071	O60260	0.63
PHKG2	5261	P15735	0.63
PITX2	5308	Q99697	0.63
PLCG1	5335	P19174	0.63
PML	5371	P29590	0.63
PRKAA1	5562	Q13131	0.63
EIF2AK2	5610	P19525	0.63
PTEN	5728	P60484	0.63
RAD21	5885	O60216	0.63
RARA	5914	P10276	0.63
RNF2	6045	Q99496	0.63
RPA1	6117	P27694	0.63
RPA2	6118	P15927	0.63
RPA3	6119	P35244	0.63
RPS6KA1	6195	Q15418	0.63
RPS6KB2	6199	Q9UBS0	0.63
SUMO3	6612	P55854	0.63
AURKA	6790	O14965	0.63
TP53	7157	P04637	0.63
TUBG1	7283	P23258	0.63
VHL	7428	P40337	0.63
WHSC1	7468	O96028	0.63
SHFM1	7979	P60896	0.63
CUL5	8065	Q93034	0.63
GAN	8139	Q9H2C0	0.63
SF3A2	8175	Q15428	0.63
UBL4A	8266	P11441	0.63
DYRK2	8445	Q92630	0.63
CUL3	8452	Q13618	0.63
CUL2	8453	Q13617	0.63
CUL1	8454	Q13616	0.63
YBX3	8531	P16989	0.63
EIF3C	8663	Q99613	0.63
EIF3D	8664	O15371	0.63
EED	8726	O75530	0.63
EIF2B3	8891	Q9NR50	0.63
EIF2B2	8892	P49770	0.63
AURKB	9212	Q96GD4	0.63
BAG3	9531	O95817	0.63
BAG2	9532	O95816	0.63
ISG15	9636	P05161	0.63
MORF4L2	9643	Q15014	0.63
CEP57	9702	Q86XR8	0.63
KIAA0101	9768	Q15004	0.63
CUL7	9820	Q14999	0.63
PAN2	9924	Q504Q3	0.63
HUWE1	10075	Q7Z6Z7	0.63
TUBGCP3	10426	Q96CW5	0.63
NXF1	10482	Q9UBU9	0.63
STK25	10494	O00506	0.63
UBD	10537	O15205	0.63
AHSA1	10598	O95433	0.63
IVNS1ABP	10625	Q9Y6Y0	0.63
MAGED2	10916	Q9UNF1	0.63
MORF4L1	10933	Q9UBU8	0.63
COPS5	10987	Q92905	0.63
CEP250	11190	Q9BV73	0.63
RPL35	11224	P42766	0.63
PNKP	11284	Q96T60	0.63
GABARAP	11337	O95166	0.63
GABARAPL2	11345	P60520	0.63
KDM4B	23030	O94953	0.63
PHLPP1	23239	O60346	0.63
OBSL1	23363	O75147	0.63
TARDBP	23435	Q13148	0.63
TRIM29	23650	Q14134	0.63
GABARAPL1	23710	Q9H0R8	0.63
NELFB	25920	Q8WX92	0.63
AGO1	26523	Q9UL18	0.63
AGO2	27161	Q9UKV8	0.63
TUBGCP4	27229	Q9UGJ1	0.63
MACROD1	28992	Q9BQ69	0.63
DDX41	51428	Q9UJV9	0.63
WWOX	51741	Q9NZC7	0.63
STK26	51765	Q9P289	0.63
DCUN1D1	54165	Q96GG9	0.63
DGCR8	54487	Q8WYQ5	0.63
HAUS2	55142	Q9NVX0	0.63
MRGBP	55257	Q9NV56	0.63
LGR4	55366	Q9BXB1	0.63
CAND1	55832	Q86VP6	0.63
USE1	55850	Q9NZ43	0.63
PBK	55872	Q96KB5	0.63
PRMT8	56341	Q9NR22	0.63
SMARCAD1	56916	Q9H4L7	0.63
SMURF1	57154	Q9HCE7	0.63
TXNDC16	57544	Q9P2K2	0.63
CEP76	79959	Q8TAP6	0.63
CEP70	80321	Q8NHQ1	0.63
UBXN6	80700	Q9BZV1	0.63
MAP1LC3B	81631	Q9GZQ8	0.63
RNF146	81847	Q9NTX7	0.63
CCDC8	83987	Q9H0W5	0.63
PHF6	84295	Q8IWS0	0.63
DOT1L	84444	Q8TEK3	0.63
UNK	85451	Q9C0B0	0.63
IGSF8	93185	Q969P0	0.63
TP53RK	112858	Q96S44	0.63
NEDD1	121441	Q8NHV4	0.63
SREK1	140890	Q8WXA9	0.63
SCARNA22	677770	N/A	0.63
ZNF689	115509	Q96CS4	0.65
NEDD4	4734	P46934	0.68
PIN1	5300	Q13526	0.68
PPP2R2B	5521	Q00005	0.68
TOP1	7150	P11387	0.68
YWHAZ	7534	P63104	0.68
KAT2B	8850	Q92831	0.68
TCERG1	10915	O14776	0.68
WBP4	11193	O75554	0.68
PRPF40A	55660	O75400	0.68
ARRB1	408	P49407	0.72
ARRB2	409	P32121	0.72
CDK9	1025	P50750	0.72
HDGF	3068	P51858	0.72
HNRNPH1	3187	P31943	0.72
IFIT3	3437	O14879	0.72
MAGOH	4116	P61326	0.72
NFKB2	4791	Q00653	0.72
POLR2J	5439	P52435	0.72
RELA	5970	Q04206	0.72
RELB	5971	Q01201	0.72
RPL10	6134	P27635	0.72
TNFRSF1B	7133	P20333	0.72
IKBKG	8517	Q9Y6K9	0.72
MAP3K14	9020	Q99558	0.72
TANK	10010	Q92844	0.72
RUVBL2	10856	Q9Y230	0.72
GPN1	11321	Q9HCN4	0.72
EXOSC4	54512	Q9NPD3	0.72
MRPL50	54534	Q8N5N7	0.72
CDKN2AIP	55602	Q9NXV6	0.72
EMD	2010	P50402	0.73
FUS	2521	P35637	0.73
SUMO2	6613	P61956	0.73
RBM39	9584	Q14498	0.73
NDRG1	10397	Q92597	0.73
MDM2	4193	Q00987	0.74
FBXW11	23291	Q9UKB1	0.74
SFN	2810	P31947	0.76
BTRC	8945	Q9Y297	0.76
PRMT1	3276	Q99873	0.77
ERG	2078	P11308	0.78
GRB2	2885	P62993	0.78
SUMO1	7341	P63165	0.78
GAS7	8522	O60861	0.78
ACTB	60	P60709	0.81
GTF2F1	2962	P35269	0.82
ILF2	3608	Q12905	0.82
RPL22	6146	P35268	0.82
RPS3A	6189	P61247	0.82
RPS25	6230	P62851	0.82
RPS27	6232	P42677	0.82
VCAM1	7412	P19320	0.82
NOP56	10528	O00567	0.82
IGF2BP3	10643	O00425	0.82
DIMT1	27292	Q9UNQ2	0.82
C14orf166	51637	Q9Y224	0.82
RIOK2	55781	Q9BVS4	0.82
MAP1LC3A	84557	Q9H492	0.82
NPM1	4869	P06748	0.83
YBX1	4904	P67809	0.83
RPS29	6235	P62273	0.83
SNW1	22938	Q13573	0.84
IKBKB	3551	O14920	0.86
DHX9	1660	Q08211	0.87