PCOSBase

Protein Description

Gene Symbol	HNRNPH2
Entrez ID	3188
Uniprot ID	P55795
Description	heterogeneous nuclear ribonucleoprotein H2 (H')
Chromosomal Location	chrX: 101,408,295-101,414,133

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Ontology	GO ID	GO Term	Definition	Evidence
BP	GO:0000398	mRNA splicing, via spliceosome	The joining together of exons from one or more primary transcripts of messenger RNA (mRNA) and the excision of intron sequences, via a spliceosomal mechanism, so that mRNA consisting only of the joined exons is produced.	TAS
BP	GO:0010467	gene expression	The process in which a gene's sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.	TAS
CC	GO:0005634	nucleus	A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.	TAS
CC	GO:0005654	nucleoplasm	That part of the nuclear content other than the chromosomes or the nucleolus.	IDA\|TAS
CC	GO:0005737	cytoplasm	All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.	IDA
CC	GO:0016020	membrane	A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.	IDA
CC	GO:0030529	intracellular ribonucleoprotein complex	An intracellular macromolecular complex containing both protein and RNA molecules.	IDA
MF	GO:0000166	nucleotide binding	Interacting selectively and non-covalently with a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose or deoxyribose.	IEA
MF	GO:0003723	RNA binding	Interacting selectively and non-covalently with an RNA molecule or a portion thereof.	TAS
MF	GO:0005515	protein binding	Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).	IPI
MF	GO:0044822	poly(A) RNA binding	Interacting non-covalently with a poly(A) RNA, a RNA molecule which has a tail of adenine bases.	IDA

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Domain ID	Description
IPR000504	RNA recognition motif domain
IPR012996	Zinc finger, CHHC-type

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Pathway ID	Pathway Term	Pathway Source
WP411	mRNA Processing	WikiPathways

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No diseases found.

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Tissue	Cell Type
adrenal gland	glandular cells
appendix	glandular cells
bone marrow	hematopoietic cells
breast	glandular cells
bronchus	respiratory epithelial cells
caudate	neuronal cells
cerebellum	cells in granular layer
cerebellum	cells in molecular layer
cerebral cortex	glial cells
cerebral cortex	neuronal cells
cervix, uterine	squamous epithelial cells
colon	endothelial cells
colon	glandular cells
colon	peripheral nerve/ganglion
duodenum	glandular cells
endometrium	glandular cells
epididymis	glandular cells
gallbladder	glandular cells
hippocampus	neuronal cells
kidney	cells in glomeruli
kidney	cells in tubules
nasopharynx	respiratory epithelial cells
oral mucosa	squamous epithelial cells
pancreas	exocrine glandular cells
pancreas	islets of Langerhans
parathyroid gland	glandular cells
placenta	decidual cells
placenta	trophoblastic cells
prostate	glandular cells
rectum	glandular cells
salivary gland	glandular cells
seminal vesicle	glandular cells
skeletal muscle	myocytes
skin	fibroblasts
skin	keratinocytes
skin	Langerhans
skin	melanocytes
skin	epidermal cells
small intestine	glandular cells
smooth muscle	smooth muscle cells
stomach	glandular cells
testis	cells in seminiferous ducts
testis	Leydig cells
thyroid gland	glandular cells
urinary bladder	urothelial cells

No databases found.

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Pubmed ID	Author	Year	Title
22951915	Haozi et al.	2012	Altered gene expression profile in cumulus cells of mature MII oocytes from patients with polycystic ovary syndrome

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Gene Symbol	Entrez ID	Uniprot ID	Score
SERPINH1	871	P50454	0.49
MAX	4149	P61244	0.49
PDCD6	10016	O75340	0.49
HNRNPH2	3188	P55795	0.63
QKI	9444	Q96PU8	0.63
TOB1	10140	P50616	0.63
RACK1	10399	P63244	0.63
RBFOX2	23543	O43251	0.63
ZSWIM5	57643	Q9P217	0.63
ZSWIM6	57688	Q9HCJ5	0.63
TEKT1	83659	Q969V4	0.63
MSI2	124540	Q96DH6	0.63
LYST	1130	Q99698	0.72
DDX1	1653	Q92499	0.72
HNRNPD	3184	Q14103	0.72
HNRNPF	3185	P52597	0.72
HNRNPH3	3189	P31942	0.72
HNRNPK	3190	P61978	0.72
MOV10	4343	Q9HCE1	0.72
PLOD2	5352	O00469	0.72
PRCP	5547	P42785	0.72
PYCR1	5831	P32322	0.72
TNK1	8711	Q13470	0.72
PLOD3	8985	O60568	0.72
APOBEC3B	9582	Q9UH17	0.72
SYNCRIP	10492	O60506	0.72
FASTK	10922	Q14296	0.72
FAM120A	23196	Q9NZB2	0.72
TARDBP	23435	Q13148	0.72
RUSC1	23623	Q9BVN2	0.72
EPC2	26122	Q52LR7	0.72
RBMX	27316	P38159	0.72
PKN3	29941	Q6P5Z2	0.72
QSER1	79832	Q2KHR3	0.72
NUDT16L1	84309	Q9BRJ7	0.72
MAK16	84549	Q9BXY0	0.72
HNRNPUL2	221092	Q1KMD3	0.72
RBM12B	389677	Q8IXT5	0.72
HNRNPM	4670	P52272	0.79
CIRBP	1153	Q14011	0.49
CNN2	1265	Q99439	0.49
CRKL	1399	P46109	0.49
DLD	1738	P09622	0.49
GMFB	2764	P60983	0.49
MCM3	4172	P25205	0.49
LGMN	5641	Q99538	0.49
YARS	8565	P54577	0.49
HNRNPDL	9987	O14979	0.49
CLIC4	25932	Q9Y696	0.49
HIBCH	26275	Q6NVY1	0.49
ISYNA1	51477	Q9NPH2	0.49
IARS2	55699	Q9NSE4	0.49
HNRNPA1L2	144983	Q32P51	0.49
C19orf25	148223	Q9UFG5	0.49
ESR2	2100	Q92731	0.55
GRB2	2885	P62993	0.56
CRY1	1407	Q16526	0.63
DDX5	1655	P17844	0.63
ERBB2	2064	P04626	0.63
ERBB3	2065	P21860	0.63
ESR1	2099	P03372	0.63
HSPA5	3309	P11021	0.63
ILF3	3609	Q12906	0.63
JUN	3725	P05412	0.63
MBNL1	4154	Q9NR56	0.63
MCM2	4171	P49736	0.63
MDM2	4193	Q00987	0.63
NEDD8	4738	Q15843	0.63
RAD21	5885	O60216	0.63
RBM4	5936	Q9BWF3	0.63
SNRPC	6631	P09234	0.63
STAU1	6780	O95793	0.63
SUMO1	7341	P63165	0.63
VCP	7415	P55072	0.63
VHL	7428	P40337	0.63
CUL5	8065	Q93034	0.63
RBM10	8241	P98175	0.63
UBL4A	8266	P11441	0.63
CUL4B	8450	Q13620	0.63
CUL3	8452	Q13618	0.63
CUL2	8453	Q13617	0.63
CUL1	8454	Q13616	0.63
EED	8726	O75530	0.63
RBM39	9584	Q14498	0.63
KIAA0101	9768	Q15004	0.63
CUL7	9820	Q14999	0.63
HDAC5	10014	Q9UQL6	0.63
PQBP1	10084	O60828	0.63
PRPF8	10594	Q6P2Q9	0.63
COPS6	10980	Q7L5N1	0.63
COPS5	10987	Q92905	0.63
HNRNPUL1	11100	Q9BUJ2	0.63
GABARAP	11337	O95166	0.63
GABARAPL2	11345	P60520	0.63
FBXW11	23291	Q9UKB1	0.63
OBSL1	23363	O75147	0.63
GABARAPL1	23710	Q9H0R8	0.63
PRPF31	26121	Q8WWY3	0.63
FBXO6	26270	Q9NRD1	0.63
AGO1	26523	Q9UL18	0.63
DDX41	51428	Q9UJV9	0.63
DCUN1D1	54165	Q96GG9	0.63
CAND1	55832	Q86VP6	0.63
SMURF1	57154	Q9HCE7	0.63
MAP1LC3B	81631	Q9GZQ8	0.63
WDR83	84292	Q9BRX9	0.63
MAP1LC3A	84557	Q9H492	0.63
UBASH3B	84959	Q8TF42	0.63
YWHAZ	7534	P63104	0.68
ARRB2	409	P32121	0.72
FN1	2335	P02751	0.72
MAGOH	4116	P61326	0.72
SRPK2	6733	P78362	0.72
EIF4A3	9775	P38919	0.72
MATR3	9782	P43243	0.72
GPN1	11321	Q9HCN4	0.72
PRMT6	55170	Q96LA8	0.72
MEPCE	56257	Q7L2J0	0.72
HSPB1	3315	P04792	0.73
SF1	7536	Q15637	0.73
HNRNPA1	3178	P09651	0.79
HNRNPA2B1	3181	P22626	0.82
PLOD1	5351	Q02809	0.82
HNRNPA3	220988	P51991	0.82
HNRNPH1	3187	P31943	0.83
HNRNPA0	10949	Q13151	0.86