| Gene Symbol | HNRNPAB |
| Entrez ID | 3182 |
| Uniprot ID | Q99729 |
| Description | heterogeneous nuclear ribonucleoprotein A/B |
| Chromosomal Location | chr5: 178,204,507-178,211,163 |
| Ontology | GO ID | GO Term | Definition | Evidence |
|---|---|---|---|---|
|
BP |
GO:0001837 |
epithelial to mesenchymal transition |
A transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell. |
ISS |
|
BP |
GO:0045893 |
positive regulation of transcription, DNA-templated |
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription. |
ISS |
|
CC |
GO:0005634 |
nucleus |
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
ISS |
|
CC |
GO:0005654 |
nucleoplasm |
That part of the nuclear content other than the chromosomes or the nucleolus. |
IDA |
|
CC |
GO:0005737 |
cytoplasm |
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
ISS |
|
CC |
GO:0030529 |
intracellular ribonucleoprotein complex |
An intracellular macromolecular complex containing both protein and RNA molecules. |
IDA |
|
CC |
GO:0090575 |
RNA polymerase II transcription factor complex |
A transcription factor complex that acts at promoters of genes transcribed by RNA polymerase II. |
ISS |
|
MF |
GO:0000166 |
nucleotide binding |
Interacting selectively and non-covalently with a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose or deoxyribose. |
IEA |
|
MF |
GO:0003700 |
transcription factor activity, sequence-specific DNA binding |
Interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription. The transcription factor may or may not also interact selectively with a protein or macromolecular complex. |
ISS |
|
MF |
GO:0003723 |
RNA binding |
Interacting selectively and non-covalently with an RNA molecule or a portion thereof. |
TAS |
|
MF |
GO:0003729 |
mRNA binding |
Interacting selectively and non-covalently with messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns. |
TAS |
|
MF |
GO:0005515 |
protein binding |
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules). |
IPI |
|
MF |
GO:0043565 |
sequence-specific DNA binding |
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding. |
ISS |
|
MF |
GO:0044822 |
poly(A) RNA binding |
Interacting non-covalently with a poly(A) RNA, a RNA molecule which has a tail of adenine bases. |
IDA |
| Domain ID | Description |
|---|---|
|
IPR000504 |
RNA recognition motif domain |
|
IPR012956 |
CARG-binding factor, N-terminal |
| Pathway ID | Pathway Term | Pathway Source |
|---|---|---|
|
WP411 |
mRNA Processing |
WikiPathways |
|
WP3527 |
Preimplantation Embryo |
WikiPathways |
| UMLS CUI | UMLS Term |
|---|---|
|
C0024668 |
Mammary Neoplasms, Experimental |
| Tissue | Cell Type |
|---|---|
|
adrenal gland |
glandular cells |
|
appendix |
glandular cells |
|
bone marrow |
hematopoietic cells |
|
breast |
adipocytes |
|
breast |
glandular cells |
|
breast |
myoepithelial cells |
|
bronchus |
respiratory epithelial cells |
|
caudate |
glial cells |
|
caudate |
neuronal cells |
|
cerebellum |
cells in granular layer |
|
cerebellum |
cells in molecular layer |
|
cerebellum |
Purkinje cells |
|
cerebral cortex |
endothelial cells |
|
cerebral cortex |
glial cells |
|
cerebral cortex |
neuronal cells |
|
cervix, uterine |
glandular cells |
|
cervix, uterine |
squamous epithelial cells |
|
colon |
endothelial cells |
|
colon |
glandular cells |
|
colon |
peripheral nerve/ganglion |
|
duodenum |
glandular cells |
|
endometrium |
cells in endometrial stroma |
|
endometrium |
glandular cells |
|
epididymis |
glandular cells |
|
esophagus |
squamous epithelial cells |
|
fallopian tube |
glandular cells |
|
gallbladder |
glandular cells |
|
heart muscle |
myocytes |
|
hippocampus |
neuronal cells |
|
kidney |
cells in glomeruli |
|
kidney |
cells in tubules |
|
liver |
bile duct cells |
|
liver |
hepatocytes |
|
lung |
macrophages |
|
lung |
pneumocytes |
|
lymph node |
germinal center cells |
|
lymph node |
non-germinal center cells |
|
nasopharynx |
respiratory epithelial cells |
|
oral mucosa |
squamous epithelial cells |
|
ovary |
ovarian stroma cells |
|
pancreas |
exocrine glandular cells |
|
pancreas |
islets of Langerhans |
|
parathyroid gland |
glandular cells |
|
placenta |
decidual cells |
|
placenta |
trophoblastic cells |
|
prostate |
glandular cells |
|
rectum |
glandular cells |
|
salivary gland |
glandular cells |
|
seminal vesicle |
glandular cells |
|
skeletal muscle |
myocytes |
|
skin |
fibroblasts |
|
skin |
keratinocytes |
|
skin |
Langerhans |
|
skin |
melanocytes |
|
skin |
epidermal cells |
|
small intestine |
glandular cells |
|
smooth muscle |
smooth muscle cells |
|
soft tissue |
adipocytes |
|
soft tissue |
chondrocytes |
|
soft tissue |
fibroblasts |
|
soft tissue |
peripheral nerve |
|
spleen |
cells in red pulp |
|
spleen |
cells in white pulp |
|
stomach |
glandular cells |
|
testis |
cells in seminiferous ducts |
|
testis |
Leydig cells |
|
thyroid gland |
glandular cells |
|
tonsil |
germinal center cells |
|
tonsil |
non-germinal center cells |
|
tonsil |
squamous epithelial cells |
|
urinary bladder |
urothelial cells |
|
vagina |
squamous epithelial cells |
| Pubmed ID | Author | Year | Title |
|---|---|---|---|
|
22617121 |
Ouandaogo et al. |
2012 |
Differences in transcriptomic profiles of human cumulus cells isolated from oocytes at GV, MI and MII stages after in vivo andin vitro oocyte maturation |
| Gene Symbol | Entrez ID | Uniprot ID | Score |
|---|---|---|---|
|
ATP6AP1 |
537 |
Q15904 |
0.49 |
|
IL7R |
3575 |
P16871 |
0.49 |
|
SNAP23 |
8773 |
O00161 |
0.49 |
|
MRPS18B |
28973 |
Q9Y676 |
0.49 |
|
MRPS7 |
51081 |
Q9Y2R9 |
0.49 |
|
MRPS25 |
64432 |
P82663 |
0.49 |
|
ACTB |
60 |
P60709 |
0.52 |
|
HOXC13 |
3229 |
P31276 |
0.63 |
|
HOXD4 |
3233 |
P09016 |
0.63 |
|
PTBP1 |
5725 |
P26599 |
0.63 |
|
RBFOX2 |
23543 |
O43251 |
0.63 |
|
PTBP2 |
58155 |
Q9UKA9 |
0.63 |
|
UBE2O |
63893 |
Q9C0C9 |
0.63 |
|
DEDD2 |
162989 |
Q8WXF8 |
0.63 |
|
EIF4EBP1 |
1978 |
Q13541 |
0.49 |
|
EWSR1 |
2130 |
Q01844 |
0.49 |
|
HSD17B10 |
3028 |
Q99714 |
0.49 |
|
HNRNPH1 |
3187 |
P31943 |
0.49 |
|
UBE2G2 |
7327 |
P60604 |
0.49 |
|
HIST3H3 |
8290 |
Q16695 |
0.49 |
|
HNRNPA0 |
10949 |
Q13151 |
0.49 |
|
AHNAK |
79026 |
Q09666 |
0.49 |
|
HNRNPA3 |
220988 |
P51991 |
0.49 |
|
YWHAG |
7532 |
P61981 |
0.52 |
|
CD247 |
919 |
P20963 |
0.56 |
|
HNRNPA2B1 |
3181 |
P22626 |
0.59 |
|
POLR3D |
661 |
P05423 |
0.63 |
|
ELAVL2 |
1993 |
Q12926 |
0.63 |
|
ERBB3 |
2065 |
P21860 |
0.63 |
|
ESR1 |
2099 |
P03372 |
0.63 |
|
EZH2 |
2146 |
Q15910 |
0.63 |
|
FN1 |
2335 |
P02751 |
0.63 |
|
HSPA5 |
3309 |
P11021 |
0.63 |
|
ITGA4 |
3676 |
P13612 |
0.63 |
|
JUN |
3725 |
P05412 |
0.63 |
|
LDHB |
3945 |
P07195 |
0.63 |
|
MCM2 |
4171 |
P49736 |
0.63 |
|
MDM2 |
4193 |
Q00987 |
0.63 |
|
MOV10 |
4343 |
Q9HCE1 |
0.63 |
|
NEDD8 |
4738 |
Q15843 |
0.63 |
|
YBX1 |
4904 |
P67809 |
0.63 |
|
NTRK1 |
4914 |
P04629 |
0.63 |
|
RNF2 |
6045 |
Q99496 |
0.63 |
|
RPA1 |
6117 |
P27694 |
0.63 |
|
RPA2 |
6118 |
P15927 |
0.63 |
|
RPA3 |
6119 |
P35244 |
0.63 |
|
SHMT2 |
6472 |
P34897 |
0.63 |
|
STAU1 |
6780 |
O95793 |
0.63 |
|
SUMO1 |
7341 |
P63165 |
0.63 |
|
VCAM1 |
7412 |
P19320 |
0.63 |
|
VHL |
7428 |
P40337 |
0.63 |
|
WHSC1 |
7468 |
O96028 |
0.63 |
|
SF1 |
7536 |
Q15637 |
0.63 |
|
CUL5 |
8065 |
Q93034 |
0.63 |
|
SF3A2 |
8175 |
Q15428 |
0.63 |
|
UBL4A |
8266 |
P11441 |
0.63 |
|
CUL4B |
8450 |
Q13620 |
0.63 |
|
CUL4A |
8451 |
Q13619 |
0.63 |
|
CUL3 |
8452 |
Q13618 |
0.63 |
|
CUL2 |
8453 |
Q13617 |
0.63 |
|
CUL1 |
8454 |
Q13616 |
0.63 |
|
EED |
8726 |
O75530 |
0.63 |
|
BTRC |
8945 |
Q9Y297 |
0.63 |
|
ATG12 |
9140 |
O94817 |
0.63 |
|
KIAA0101 |
9768 |
Q15004 |
0.63 |
|
CUL7 |
9820 |
Q14999 |
0.63 |
|
PAN2 |
9924 |
Q504Q3 |
0.63 |
|
NXF1 |
10482 |
Q9UBU9 |
0.63 |
|
IVNS1ABP |
10625 |
Q9Y6Y0 |
0.63 |
|
USP19 |
10869 |
O94966 |
0.63 |
|
COPS6 |
10980 |
Q7L5N1 |
0.63 |
|
COPS5 |
10987 |
Q92905 |
0.63 |
|
GABARAP |
11337 |
O95166 |
0.63 |
|
GABARAPL2 |
11345 |
P60520 |
0.63 |
|
SNW1 |
22938 |
Q13573 |
0.63 |
|
FBXW11 |
23291 |
Q9UKB1 |
0.63 |
|
OBSL1 |
23363 |
O75147 |
0.63 |
|
TARDBP |
23435 |
Q13148 |
0.63 |
|
GABARAPL1 |
23710 |
Q9H0R8 |
0.63 |
|
DROSHA |
29102 |
Q9NRR4 |
0.63 |
|
EEF2K |
29904 |
O00418 |
0.63 |
|
DDX41 |
51428 |
Q9UJV9 |
0.63 |
|
DCUN1D1 |
54165 |
Q96GG9 |
0.63 |
|
RIOK2 |
55781 |
Q9BVS4 |
0.63 |
|
CAND1 |
55832 |
Q86VP6 |
0.63 |
|
USE1 |
55850 |
Q9NZ43 |
0.63 |
|
SMURF1 |
57154 |
Q9HCE7 |
0.63 |
|
POLR1E |
64425 |
Q9GZS1 |
0.63 |
|
LIN28A |
79727 |
Q9H9Z2 |
0.63 |
|
MAP1LC3B |
81631 |
Q9GZQ8 |
0.63 |
|
MAP1LC3A |
84557 |
Q9H492 |
0.63 |
|
UNK |
85451 |
Q9C0B0 |
0.63 |
|
SCARNA22 |
677770 |
N/A |
0.63 |
|
ERG |
2078 |
P11308 |
0.68 |
|
H2AFX |
3014 |
P16104 |
0.72 |
|
HMGA1 |
3159 |
P17096 |
0.72 |
|
HNRNPU |
3192 |
Q00839 |
0.72 |
|
IFIT2 |
3433 |
P09913 |
0.72 |
|
IFIT3 |
3437 |
O14879 |
0.72 |
|
PTTG1 |
9232 |
O95997 |
0.72 |
|
EMC2 |
9694 |
Q15006 |
0.72 |
|
SYNCRIP |
10492 |
O60506 |
0.72 |
|
MEPCE |
56257 |
Q7L2J0 |
0.72 |
|
SGO1 |
151648 |
Q5FBB7 |
0.72 |
|
SUMO2 |
6613 |
P61956 |
0.73 |
|
AES |
166 |
Q08117 |
0.76 |
|
ARHGDIA |
396 |
P52565 |
0.76 |
|
CNBP |
7555 |
P62633 |
0.76 |
|
HNRNPD |
3184 |
Q14103 |
0.82 |
|
HNRNPA1 |
3178 |
P09651 |
0.87 |
|
TP63 |
8626 |
Q9H3D4 |
0.89 |