Protein Description

Gene Symbol HDLBP
Entrez ID 3069
Uniprot ID Q00341
Description high density lipoprotein binding protein
Chromosomal Location chr2: 241,227,264-241,317,061
Ontology GO ID GO Term Definition Evidence

BP

GO:0006869

lipid transport

The directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Lipids are compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent.

IEA

BP

GO:0008203

cholesterol metabolic process

The chemical reactions and pathways involving cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones. It is a component of the plasma membrane lipid bilayer and of plasma lipoproteins and can be found in all animal tissues.

IEA

BP

GO:0098609

cell-cell adhesion

The attachment of one cell to another cell via adhesion molecules.

IEA

CC

GO:0005634

nucleus

A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

IEA

CC

GO:0005737

cytoplasm

All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

IDA

CC

GO:0005886

plasma membrane

The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

TAS

CC

GO:0005913

cell-cell adherens junction

An adherens junction which connects a cell to another cell.

IDA

CC

GO:0034364

high-density lipoprotein particle

A lipoprotein particle with a high density (typically 1.063-1.21 g/ml) and a diameter of 5-10 nm that contains APOAs and may contain APOCs and APOE; found in blood and carries lipids from body tissues to the liver as part of the reverse cholesterol transport process.

IEA

MF

GO:0008289

lipid binding

Interacting selectively and non-covalently with a lipid.

TAS

MF

GO:0044822

poly(A) RNA binding

Interacting non-covalently with a poly(A) RNA, a RNA molecule which has a tail of adenine bases.

IDA

MF

GO:0098641

cadherin binding involved in cell-cell adhesion

Any cadherin binding that occurs as part of the process of cell-cell adhesion.

IDA

Domain ID Description

IPR004087

K Homology domain

IPR004088

K Homology domain, type 1

IPR015946

K homology domain-like, alpha/beta

No pathways found.

UMLS CUI UMLS Term

C0004352

Autistic Disorder

Tissue Cell Type

pancreas

exocrine glandular cells

placenta

decidual cells

placenta

trophoblastic cells

No databases found.

Pubmed ID Author Year Title

22951915

Haozi et al.

2012

Altered gene expression profile in cumulus cells of mature MII oocytes from patients with polycystic ovary syndrome

Gene Symbol Entrez ID Uniprot ID Score

ZW10

9183

O43264

0.49

VPS26A

9559

O75436

0.49

GLMN

11146

Q92990

0.49

SAC3D1

29901

A6NKF1

0.49

VPS36

51028

Q86VN1

0.49

VPS29

51699

Q9UBQ0

0.49

DDX43

55510

Q9NXZ2

0.49

VPS35

55737

Q96QK1

0.49

VPS25

84313

Q9BRG1

0.49

ZNF598

90850

Q86UK7

0.49

CLUH

23277

O75153

0.56

FAU

2197

P62861

0.63

FLNC

2318

Q14315

0.63

XRCC5

7520

P13010

0.63

IKBKG

8517

Q9Y6K9

0.63

DYNLL1

8655

P63167

0.63

EIF2A

83939

Q9BY44

0.63

PRKDC

5591

P78527

0.72

ADAR

103

P55265

0.73

DHX9

1660

Q08211

0.73

CTCF

10664

P49711

0.75

CSNK2A1

1457

P68400

0.76

PLAUR

5329

Q03405

0.49

UPF1

5976

Q92900

0.49

S100A10

6281

P60903

0.49

S100A11

6282

P31949

0.49

SMS

6611

P52788

0.49

TTC4

7268

O95801

0.49

TTK

7272

P33981

0.49

TYRO3

7301

Q06418

0.49

UBE2A

7319

P49459

0.49

UBE4B

10277

O95155

0.49

TOPBP1

11073

Q92547

0.49

ATP6V1B2

526

P21281

0.56

ESR1

2099

P03372

0.56

PSMD12

5718

O00232

0.56

MEX3C

51320

Q5U5Q3

0.56

UBA6

55236

A0AVT1

0.59

ACTL6A

86

O96019

0.63

ARF6

382

P62330

0.63

BPGM

669

P07738

0.63

CDC5L

988

Q99459

0.63

CDK2

1017

P24941

0.63

CYP1A1

1543

P04798

0.63

ERBB2

2064

P04626

0.63

FLNB

2317

O75369

0.63

HSPA9

3313

P38646

0.63

HSPB1

3315

P04792

0.63

JUN

3725

P05412

0.63

SMAD4

4089

Q13485

0.63

MDM2

4193

Q00987

0.63

NTRK1

4914

P04629

0.63

SERPINB5

5268

P36952

0.63

SERPINB3

6317

P29508

0.63

SUMO2

6613

P61956

0.63

SOS1

6654

Q07889

0.63

STK4

6789

Q13043

0.63

SUV39H1

6839

O43463

0.63

VCP

7415

P55072

0.63

WHSC1

7468

O96028

0.63

COPS5

10987

Q92905

0.63

SNW1

22938

Q13573

0.63

OBSL1

23363

O75147

0.63

CBX5

23468

P45973

0.63

SIRT7

51547

Q9NRC8

0.63

WWOX

51741

Q9NZC7

0.63

LGR4

55366

Q9BXB1

0.63

KCMF1

56888

Q9P0J7

0.63

SLC25A32

81034

Q9H2D1

0.63

CCDC8

83987

Q9H0W5

0.63

ZCCHC7

84186

Q8N3Z6

0.63

TMEM171

134285

Q8WVE6

0.63

PTCRA

171558

Q6ISU1

0.63

SCARNA22

677770

N/A

0.63

ARRB1

408

P49407

0.72

KIF11

3832

P52732

0.72

MLH1

4292

P40692

0.72

FAM46A

55603

Q96IP4

0.73

XPOT

11260

O43592

0.75

MAGEA6

4105

P43360

0.76

AKTIP

64400

Q9H8T0

0.76

YBX1

4904

P67809

0.82