Protein Description

Gene Symbol GRSF1
Entrez ID 2926
Uniprot ID Q12849
Description G-rich RNA sequence binding factor 1
Chromosomal Location chr4: 70,815,782-70,839,945
Ontology GO ID GO Term Definition Evidence

BP

GO:0006378

mRNA polyadenylation

The enzymatic addition of a sequence of 40-200 adenylyl residues at the 3' end of a eukaryotic mRNA primary transcript.

TAS

BP

GO:0008033

tRNA processing

The process in which a pre-tRNA molecule is converted to a mature tRNA, ready for addition of an aminoacyl group.

IEA

BP

GO:0009952

anterior/posterior pattern specification

The regionalization process in which specific areas of cell differentiation are determined along the anterior-posterior axis. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism.

IEA

BP

GO:0016331

morphogenesis of embryonic epithelium

The process in which the anatomical structures of embryonic epithelia are generated and organized.

IEA

CC

GO:0005737

cytoplasm

All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

TAS

CC

GO:0005739

mitochondrion

A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.

IDA

CC

GO:0035770

ribonucleoprotein granule

A non-membranous macromolecular complex containing proteins and translationally silenced mRNAs. RNA granules contain proteins that control the localization, stability, and translation of their RNA cargo. Different types of RNA granules (RGs) exist, depending on the cell type and cellular conditions.

IDA

CC

GO:0042645

mitochondrial nucleoid

The region of a mitochondrion to which the DNA is confined.

IDA

MF

GO:0000166

nucleotide binding

Interacting selectively and non-covalently with a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose or deoxyribose.

IEA

MF

GO:0003723

RNA binding

Interacting selectively and non-covalently with an RNA molecule or a portion thereof.

TAS

MF

GO:0003729

mRNA binding

Interacting selectively and non-covalently with messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns.

TAS

MF

GO:0044822

poly(A) RNA binding

Interacting non-covalently with a poly(A) RNA, a RNA molecule which has a tail of adenine bases.

IDA

Domain ID Description

IPR000504

RNA recognition motif domain

IPR033106

G-rich sequence factor 1

IPR034424

GRSF-1, RNA recognition motif 2

IPR034425

GRSF-1, RNA recognition motif 1

IPR034426

GRSF-1, RNA recognition motif 3

No pathways found.

No diseases found.

Tissue Cell Type

adrenal gland

glandular cells

colon

glandular cells

duodenum

glandular cells

esophagus

squamous epithelial cells

gallbladder

glandular cells

kidney

cells in tubules

lymph node

germinal center cells

nasopharynx

respiratory epithelial cells

salivary gland

glandular cells

stomach

glandular cells

thyroid gland

glandular cells

tonsil

germinal center cells

No databases found.

Pubmed ID Author Year Title

22951915

Haozi et al.

2012

Altered gene expression profile in cumulus cells of mature MII oocytes from patients with polycystic ovary syndrome

Gene Symbol Entrez ID Uniprot ID Score

ATP5B

506

P06576

0.63

ATP5O

539

P48047

0.63

BDKRB2

624

P30411

0.63

C1QBP

708

Q07021

0.63

HSD17B10

3028

Q99714

0.63

HADHA

3030

P40939

0.63

HSPA9

3313

P38646

0.63

MDH2

4191

P40926

0.63

NME4

4833

O00746

0.63

RPL28

6158

P46779

0.63

TFAM

7019

Q00059

0.63

DAP3

7818

P51398

0.63

RPL14

9045

P50914

0.63

MRPS31

10240

Q92665

0.63

MRPL28

10573

Q13084

0.63

PDLIM5

10611

Q96HC4

0.63

DHX30

22907

Q7L2E3

0.63

MRPS27

23107

Q92552

0.63

HARS2

23438

P49590

0.63

ACOT9

23597

Q9Y305

0.63

MRPS28

28957

Q9Y2Q9

0.63

MRPL2

51069

Q5T653

0.63

MRPL4

51073

Q9BYD3

0.63

MRPS7

51081

Q9Y2R9

0.63

MRPS2

51116

Q9Y399

0.63

MRPL48

51642

Q96GC5

0.63

PTCD3

55037

Q96EY7

0.63

MTPAP

55149

Q9NVV4

0.63

MRM3

55178

Q9HC36

0.63

MRPS22

56945

P82650

0.63

MRPL47

57129

Q9HD33

0.63

MRPS25

64432

P82663

0.63

MRPS26

64949

Q9BYN8

0.63

MRPS15

64960

P82914

0.63

MRPL11

65003

Q9Y3B7

0.63

MRPS34

65993

P82930

0.63

MRPL24

79590

Q96A35

0.63

PNPT1

87178

Q8TCS8

0.63

MRPL21

219927

Q7Z2W9

0.63

IARS2

55699

Q9NSE4

0.49

ICT1

3396

Q14197

0.63

NEDD8

4738

Q15843

0.63

RPS6KA1

6195

Q15418

0.63

SUMO1

7341

P63165

0.63

CUL5

8065

Q93034

0.63

CUL3

8452

Q13618

0.63

CUL2

8453

Q13617

0.63

CUL1

8454

Q13616

0.63

KIAA0101

9768

Q15004

0.63

NXF1

10482

Q9UBU9

0.63

GABARAP

11337

O95166

0.63

TARDBP

23435

Q13148

0.63

FTSJ1

24140

Q9UET6

0.63

TRMT10C

54931

Q7L0Y3

0.63

CAND1

55832

Q86VP6

0.63

PSMD10

5716

O75832

0.68

RPS6KA2

6196

Q15349

0.72